Regidron: what is the medicine for and how to use it correctly

Compound

Regidron includes:

• 10 g dextrose;
• 3.5 g sodium chloride;
• 2.9 g sodium citrate ;
• 2.5 g potassium chloride.

In the solution obtained by dissolving 1 dose of powder (the contents of one sachet) in 1000 mg of water, the active ingredients are contained in the following concentrations: NaCl - 59.9 mmol, KCl - 33.5 mmol, Na citrate (in the form of dihydrate) - 9.9 mmol, dextrose - 55.5 mmol, citrate ions - 9.9 mmol, Cl- - 93.4 mmol, K+ - 33.5 mmol, Na+ - 89.6 mmol.

Pharmacodynamics and pharmacokinetics

What is Regidron?

The drug solution is used to correct the loss of fluid and electrolytes by the body during vomiting and/or diarrhea.

Pharmacodynamics

The glucose contained in the drug promotes the absorption of citrates and salts, which helps maintain metabolic acidosis .

The osmolarity of the finished solution is 260 mOsm/l, and its medium is slightly alkaline (pH 8.2). Compared to standard solutions that WHO recommends for use as part of rehydration therapy , Regidron has a lower osmolarity. Its sodium content is also lower than its analogues, and the potassium concentration is slightly higher.

There is sufficient evidence that hypoosmolar solutions are more effective, lower sodium concentrations help prevent the development of hypernatremia , and increased potassium levels promote faster recovery of potassium levels.

Pharmacokinetics

The pharmacokinetics of glucose, electrolytes and water, which are part of the solution, corresponds to the nature of the pharmacokinetics of these substances in the body.

Indications for use of Regidron powder

Indications for the use of Regidron are conditions accompanied by water-electrolyte imbalance (WEB).

When asked what the drug Regidron helps with, the manufacturer in the annotation for the drug indicates that the use of the drug is advisable:

• if it is necessary to correct acidosis during diarrhea , which is accompanied by mild or moderate dehydration (for example, adults and children should drink the solution when body weight loss is from 3 to 10%);
• for heat injuries associated with EBV disorders;
• in cases of dangerous desalination of the body, when the level of chlorides in the urine does not exceed 2 g/l.

Powder - what is it used for preventive purposes?

The prophylactic use of Regidron is indicated for physical and thermal stress leading to intense sweating (when the body loses 750 grams (or more) of weight per hour), as well as in situations where a person loses over 4 kg of weight during the working day.

Why do you need Regidron for children?

Like adults, children are prescribed Regidron when there is a threat of dehydration, including vomiting and diarrhea, which are the result of gastrointestinal infections , as well as in situations where dehydration develops against the background of heat stroke.

However, if the child's stool is watery and contains bloody impurities, the body temperature has risen above 39 ° C, the child looks sleepy, lethargic and exhausted, he has stopped urinating, there is acute pain in the abdominal cavity, and diarrhea and vomiting occur more than five times per day, you need to urgently consult a doctor.

Stages of drug therapy

The standard regimen for a patient in a clinical setting is pharmacotherapy, selected individually after examination. The main steps to restore health after excessive stress are:

1. Infusion effect. For treatment, salt formulations (dropper) are used, where the components are Ringer-Lakaa solution (or, as an alternative, saline solution), anti-puffiness agents, glucose 5%, and various sorbents. The dropper acts intensively and delicately, relieving him of the consequences of poisoning.
2. Sedative pharmacotherapy. Clinics use strong sedatives and sedatives. This prescription is advisable for increased irritability, aggression, and neuroses. The treatment regimen makes it possible to improve the quality of sleep and normalize vital processes. To achieve the effect, it can be “Reliuma”, “Phenazepam”, etc.
3. Additional activities. In addition to the main compounds, others are prescribed: for seizures, to stabilize blood pressure, improve heart function, and relieve headaches. In standard practice, the course is supplemented with Pannangin, Verepamil and their analogues. Doses of magnesia, neuroleptics, and analgesics are calculated. Note that the duration of pain after withdrawal from binge drinking depends on the length of alcoholism and the age of the patient.

In some cases, quick action should not be expected. Withdrawal symptoms (especially in older adults) often last 7 to 10 days. To stop binge drinking, it is very important to monitor the patient around the clock by medical staff. This not only makes the discomfort less burdensome, but also reduces the risk of relapse.

Contraindications

The manufacturer's instructions list the following contraindications for the use of the medicine:

• intestinal obstruction;
• unconscious state;
• kidney dysfunction;
• cholera- related diarrhea;
• intolerance to Regidron components.

A relative contraindication is diabetes mellitus (type I or II).

Regidron powder, instructions for use (Method and dosage)

How to dilute the powder and how to drink Regidron solution for adults?

Regidron is taken orally at any time of the day, without reference to meal times.

To prepare a rehydration solution, the powder is dissolved in warm (optimal temperature 35-40 °C) boiled water. For medicinal purposes, 2.39 grams of powder should be diluted in 0.5 cups of liquid (100 ml), half a liter of water is taken for 11.95 grams of powder, and 1 liter for 23.9 grams.

If Regidron is taken for preventive purposes, twice as much water must be used to dissolve the powder: 200 ml, 1 and 2 liters, respectively.

How to take Regidron for adults?

For mild diarrhea, For moderate diarrhea, the daily dose is from 80 to 100 ml/kg. Treatment usually lasts 3-4 days. The signal for its cessation is the end of diarrhea.

For maintenance therapy until the damaged EBV is restored and diarrhea stops, the solution should also be taken at a rate of 80-100 ml/kg/day.

In the first six to ten hours, the patient should receive Regidron in a volume twice as large as the loss of body weight caused by indigestion. At this stage of treatment there is no need to administer other fluids.

If diarrhea continues even after correction of dehydration, the patient should receive a total of 8.3 to 27 liters of fluids per day, depending on weight. To compensate for the body's needs, Regidron, water and other liquids are used. The feeding regimen is selected by the doctor depending on the age and weight of the patient.

If you have nausea and/or vomiting, it is best to drink the liquid chilled and in small, repeatable doses. The use of a nasogastric tube is allowed, but in this case, rehydration should be carried out under the supervision of a physician.

For convulsions (thermal or caused by drinking sickness) and other EBV disorders, fractional use of Regidron is indicated - 100-150 ml each. In this case, in the first half hour the patient should receive from 0.5 to 0.9 liters of a solution of rehydration salts.

Then, until the symptoms of heat injury and water/electrolyte deficiency completely disappear, the patient should receive the same dose of solution every forty minutes,

To prevent EBV disorders during extreme physical or thermal stress, the solution is taken in small sips each time thirst appears. Stop taking it as your thirst quenches.

Use of Regidron for poisoning

In case of poisoning, Regidron is taken regardless of the time of meal, often and in small sips (a large amount of liquid taken at one time can cause another attack of vomiting).

The dose is calculated depending on the patient's weight. So, for example, an adult weighing 80 kg should receive 0.8 liters of solution (10 ml/kg) within the first hour.

As the patient's condition improves, the dose is reduced to 5 ml/kg. If symptoms recur, the volume of administered medication is again increased to the original volume.

How to breed Regidron for children?

According to the instructions for use of Regidron for children, to prepare a drink, the contents of one package should be diluted in a liter of boiled water cooled to body temperature. For diarrhea in young children, the powder should be diluted in a larger volume of water to reduce the sodium concentration in the finished solution.

The prepared solution can be used within 24 hours, but it should be stored in the refrigerator.

Children are recommended to drink Regidron solution in small sips after each loose stool.

The instructions for Regidron for children warn that the drug should not be combined with other medications or diluted in any liquid other than water.

How to take Regidron for children?

Before starting treatment, the child should be weighed to assess the degree of dehydration and weight loss.

Nutrition or breastfeeding during the period of use of the drug is not interrupted or resumed immediately after rehydration. During treatment, the diet should not contain foods rich in simple carbohydrates and fats.

The use of the drug begins as soon as the child begins to have diarrhea. Treatment, as in adults, lasts 3-4 days until stool normalizes.

In the first ten hours, Regidron for children should be used at a dose of 30-60 ml/kg (taking into account the degree of dehydration). The average dose for a child is 2-3 tbsp. spoons per kilogram of body weight. If symptoms of dehydration decrease, the dose can be reduced to 10 ml/kg.

For newborn infants and young children, the medicine is given 5-10 ml every five to ten minutes during the first four to six hours.

When vomiting, it is better to give the solution to the child chilled.

An important rule for rehydration therapy for gastrointestinal infections is the absence of abundant drinking and food. If a child asks for food, preference should be given to low-fat, light foods.

When self-medication is dangerous

Full course of pharmacotherapy - prescription of drugs and complex. They are necessary to remove the consequences of poisoning: removing toxins, stabilizing the mental and emotional background, restoring the functions of internal organs using gentle methods. Procedures can be carried out both at home and in a clinic under the constant supervision of staff. Indications for the latter option would be:

• condition that lasts longer than 7 days;
• symptoms of psychosis or pronounced neuroses;
• somatic abnormalities;
• age up to 18 years, after 70 years (according to the law, assistance to old people and adolescents is provided only in clinical settings);
• chronic diseases.

For immediate departure of a team of paramedics from a narcological clinic, the patient’s consent will be required. Observation by a specialist continues until signs of improvement appear. However, even after this, it is impossible to leave an alcoholic without control, since this is the most common cause of relapse.

Overdose

When using a solution that is too concentrated, or when taking too much of a solution, there is a high risk of developing hypernatremia . With reduced renal function, hyperkalemia and metabolic alkalosis .

Hypernatremia manifests itself:

• neuromuscular excitation;
• weakness;
• confusion;
• drowsiness;
• coma;
• stopping breathing.

Manifestations of metabolic alkalosis are neuromuscular excitation, decreased ventilation, and tetanic convulsions .

In case of severe overdose with severe symptoms of hypernatremia or metabolic alkalosis, the administration of Regidron is stopped. Further treatment is carried out taking into account the results of laboratory tests.

special instructions

In case of severe dehydration, when the loss of body weight exceeds 10%, and the patient develops anuria , treatment begins with the use of rehydration agents for intravenous administration and only after that Regidron is prescribed.

The prescribed dose should not be exceeded unless a deficiency of electrolyte ions is confirmed by laboratory tests.

Using a solution that is too concentrated may cause the development of hypernatremia , so the dosage recommended by the manufacturer should not be exceeded.

Do not add sugar or honey to the solution. Food can be consumed immediately after rehydration.

Regidron for vomiting is given to children and adults ten minutes after the attack. The medicine should be taken in small sips and slowly.

If dehydration is a consequence of diabetes mellitus , chronic renal failure or any other chronic pathology in which the electrolyte, acid-base or carbohydrate balance is disturbed, careful monitoring of the patient's condition is required when carrying out rehydration using Regidron.

The appearance of loose, bloody stools, the patient’s inability to answer questions, rapid fatigue, slow speech, drowsiness, fever up to 39 degrees or higher, anuria , diarrhea lasting more than five days in a row, as well as its sudden cessation due to the appearance of severe pain, are a reason to contact a doctor immediately.

Treatment at home in these cases is impossible and ineffective.

Regidron does not slow down the reaction rate, does not impede thinking processes and does not affect the ability to operate machinery or a vehicle.

What else you should know

Alcohol abuse for more than 3 days causes severe intoxication. At this time, the functioning of organs is disrupted. However, timely assistance to the patient by a doctor is not the only option. Equally important is the support of people close to him. Therapy in a hospital is generally similar to procedures at home. As recommended, it includes sedatives, modern antipsychotics, and possibly tranquilizers. The regimen includes anticonvulsants, detoxifiers, and hepatoprotectors. The method is supplemented with metabolic components and opioid receptor blockers. Vitamin complexes with antioxidants, natural dietary supplements, and disulfiram-based tablets are considered mandatory for recovery in a short time.

Analogues of Regidron. How to replace Regidron at home?

Level 4 ATX code matches:
Gastrolit

Synonyms of the drug are:

• Hydrovit
• Hydrovit Forte
• Trihydron
• Reosolan
• Citraglucosolan

The Orion Pharma company also produces the drug Regidron Bio . Thanks to the presence of lactobacilli Rhamnosus GG and the prebiotic maltodextrin, which stimulates their growth, this product not only replenishes fluid loss, but also helps restore and maintain the natural intestinal microflora.

Like Regidron, all of the above drugs have a balanced composition and a specific salty taste, which children often do not like. Any attempt to improve the organoleptic properties of ready-made rehydration solutions using additives (honey, sugar, etc.) leads to a change in the original composition and a decrease in efficiency.

The most suitable analogue of Regidron for children is Humana Elektrolyt , which is more adapted for use in young patients.

Intended for children from birth to three years old, it contains fennel; for children over three years of age, the manufacturer produces powders with a pleasant raspberry or banana flavor.

How to make Regidron at home?

If the situation requires rehydration therapy, but the necessary drug is not at hand, there are several ways to prepare Regidron at home.

To obtain a solution suitable for soldering a child, dissolve sugar (20-30 g), salt (3-3.5 g), baking soda (2-2.5 g) in a liter of boiled (and cooled to 35-40 ° C) water ). When all the ingredients are dissolved, the medicine is taken according to the same scheme as the pharmaceutical drug.

A slightly simpler recipe involves adding ¼ teaspoon of baking soda, a similar amount of salt, and 2 tablespoons of sugar to 0.5 liters of warm boiled water.

The difference from the original drug and the disadvantage of such drinks is the lack of potassium in them. To prepare a solution as close as possible to Regidron, potassium chloride should also be added to the water. The recipe is as follows: 4 tbsp. spoons of sugar, 0.5 teaspoons of salt, 0.5 teaspoons of baking soda and the same amount of potassium chloride per 1 liter of water.

Dr. Komarovsky recommends that mothers of small children always keep a packet of Regidron in their medicine cabinet, and if the drug is not available, use a decoction of rose hips or herbs, mineral water or dried fruit compote to water the child.

The temperature of the drink should be as close as possible to body temperature. This will allow the liquid to be absorbed into the blood as quickly as possible.

How to Know What to Do

Interrupting binge drinking on your own is an extremely difficult decision, both mentally and physiologically. And not every alcoholic can refuse a dose that, albeit for a short time, relieves pain. During this period, you need the attention of a doctor, but more support from people you trust. The problem is quite common and is covered in the press, TV, and resources on the Internet. Information for relatives is available in private and public drug treatment centers, which are ready to consult, examine and help the addict get rid of the debilitating disease. Consultations with narcologists and psychologists are available free of charge; hotlines operate 24 hours a day.

Author of the article: Yakovlev Evgeniy Anatolyevich

Narcologist, Candidate of Medical Sciences.

Reviews about Regidron

Regidron is an easy-to-use and very effective remedy for preventing dehydration during vomiting and diarrhea. Most people who leave reviews about Regidron believe that the drug should be in every first aid kit.

Many patients cite the specific taste of the solution as its only drawback. If an adult still manages to drink the required amount of medicine, then persuading a child to take even part of the required dose is often quite difficult.

For this reason, many mothers advise choosing not Regidron for children, but its analogues with a more pleasant taste (for example, Regidron Optim, which differs from Regidron in the concentration of active substances and the presence of lemon flavoring in the composition of excipients).

How to stop binge drinking without complications, what to take

There are a number of medications available over the counter in pharmacies. Their purpose is to interrupt the disease, eliminate withdrawal symptoms and convulsions, and quickly restore ability to work. Firstly, these include vitamins and in particular group B (neuromultivitis, neurobics, etc.). Secondly, Glycine and Gromecin to stabilize metabolism and brain functions. Among folk recipes, a common method is to drink milk thistle decoction, which is good for the liver (reduces load). But dangerous drinks include drinking tea or coffee, stimulating the gag reflex, and washing the stomach with a solution of potassium manganese. In the first case, blood and intracranial pressure dangerously increases, in the second, severe dehydration occurs, and in the third, significant damage to the mucous membranes is observed.

The most common are several subgroups of medications that act to achieve specific results. For this, narcology uses pills:

• reducing the need to drink;
• causing autonomic disorders at any dose (nausea, vomiting, diarrhea, skin rashes, etc.);
• painkillers that reduce anxiety;
• neutralizing ethanol.

But no matter how effective modern means are, their use is not a treatment, but the first step towards it, giving a chance for a full life. Medicines that fall into this category make it possible to regain clear thinking, in fact, to obtain consent for procedures and perform medical procedures.

How much does Regidron cost at the pharmacy?

The price of Regidron BIO in Russia is about 500 rubles (packages 6.4 g, package No. 5). The cost of 1 sachet is about 100 rubles.

The price of Regidron in Ukrainian pharmacies is about 250 UAH. (packages 18.9 g, package No. 20). You can buy Regidron Optim (10.7 g sachets, package No. 20) for an average of 300 UAH. The price of 1 sachet of Regidron is 15 UAH.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Regidron BIO powder for intravenous injection solution.
  approx. sachet 6.4g 5 pcs. SIIT srl RUR 551 order

Pharmacy Dialogue

• Regidron BIO (pack 6.4 g No. 5)SIIT srl IT

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  25 rub. order

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Pharmacy24

• Regidron Optim 10.7g N20 powder for oral solution Recipharm Parets S.L., Spain
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• Regidron Bio 6.4 g No. 10 powder sachet (A and B) Es.Ai.Ai.Ti srl, Italy for Orion Corporation, Finland

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PaniPharmacy

• Regidron Optim Regidron Optim powder for solution, sachet 10.7g No. 20 Finland, Orion

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• Regidron Regidron powder dosed 18.9g No. 20 Finland, Orion

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