Troxerutin is the number one gel in the treatment of hematomas, bruises and contusions. Proof of its effectiveness is that it is included in the list of vital and important medicines in Russia. And the availability and low price of the gel allow everyone to choose it.
Author of the article / Site experts Shulepin Ivan Vladimirovich, traumatologist-orthopedist, highest qualification category
Total work experience over 25 years. In 1994 he graduated from the Moscow Institute of Medical and Social Rehabilitation, in 1997 he completed a residency in the specialty “Traumatology and Orthopedics” at the Central Research Institute of Traumatology and Orthopedics named after. N.N. Prifova.
Pharmacology
The medicine helps relax the smooth muscles of internal organs. After taking it, there is an improvement in the tone of the walls of blood vessels, they become less distensible, as a result of which blood stagnation disappears, the likelihood of edema decreases, and the severity of inflammatory processes decreases.
Capsules for oral administration are easily excreted from the stomach. The maximum concentration of the active element occurs 3-7 hours after administration. The second peak occurs approximately 28 hours later. The drug leaves the body completely within a day. Most of it is excreted by the liver, and a small part is excreted by the kidneys.
When the gel is applied locally, the constituent elements do not leak into the blood, but they still penetrate into the tissue adjacent to the skin.
Reviews from experts and consumers
Pharmacists and ordinary customers note the medicinal quality of Troxerutin gel. Reviews from almost all users agree on one thing: the gel helps eliminate bruises and swelling, and the consequences of contusions quickly and effectively. Especially if it was inflicted almost immediately after the injury. Buyers also note the availability of the product.
Summing up the advantages and disadvantages of Troxerutin gel, it can be noted that there are more of the former. This is an effectiveness proven by doctors over the years, and low cost. It is Troxerutin that will provide guaranteed first aid in case of injury.
Troxerutin is one of the cheapest remedies that can really fight varicose veins
In what cases is it used
Taking the drug is advisable in the following cases:
- varicose veins (including when carrying a child);
- chronic venous insufficiency;
- haemorrhoids;
- tissue swelling;
- influenza, measles, scarlet fever;
- vascular effects resulting from radiation exposure;
- high permeability of capillary walls.
After surgery on the veins, it can be taken for preventive purposes.
How to take capsules correctly
The tablets must be taken with food. The capsule cannot be chewed or dissolved; it must be swallowed whole with water. The permissible dose is 1 tablet three times a day. If the drug is taken as an auxiliary medicine, then you need to take 2 tablets per day. The duration of the therapeutic course is 20-28 days. Only a doctor can extend the course of treatment.
Depending on the manufacturer of the drug, there may be minor differences in the instructions for use. Taking Troxerutin Zentiva capsules is similar to the regimen described above, while Troxerutin Vramed in the first days of therapy should be taken 1 capsule no more than 3 times a day, after which switch to maintenance therapy, taking 1 tablet per day.
Troxerutin-MIC involves administering the drug intramuscularly or intravenously. One injection will require 0.5 active substance. The procedure should be carried out every other day. The course must include at least 5 injections. After the injections, you can begin treatment with tablets.
Troxerutin
Dosage form: gel for external use.
Composition per 100 g:
active ingredient: troxerutin (in terms of 100% substance) – 2.00 g;
excipients: carbomer 940 - 0.6 g, disodium edetate - 0.050 g, benzalkonium chloride - 0.0575 g, sodium hydroxide 30% - 0.700 g, purified water - up to 100 g.
Description: homogeneous transparent gel from yellow to light brown or yellow-green.
Pharmacotherapeutic group: venotonic and venoprotective agent.
ATX code: C05CA04.
pharmachologic effect
Pharmacodynamics. Troxerutin is a flavonoid (derivative of rutin), has P-vitamin activity: it has venotonic, venoprotective, decongestant, anti-inflammatory, anticoagulant and antioxidant effects. Its pharmacodynamic properties are associated with the participation of troxerutin in redox processes and inhibition of hyaluronidase. By inhibiting hyaluronidase, troxerutin stabilizes hyaluronic acid in cell membranes and reduces the permeability and fragility of capillaries, increasing their tone. It has antioxidant activity, which prevents the oxidation of ascorbic acid, adrenaline and lipids. Prevents damage to the basement membrane of endothelial cells when exposed to various factors. Troxerutin reduces exudative inflammation in the vascular wall, limiting the adhesion of platelets to its surface. As a result of treatment with troxerutin, the feeling of heaviness in the legs disappears, tissue swelling decreases, and trophism improves.
Pharmacokinetics. When the gel is applied to the affected area, the active substance quickly penetrates the epidermis, after 30 minutes it is found in the dermis, and after 2-5 hours in the subcutaneous fatty tissue.
Indications for use:
Varicose veins, chronic venous insufficiency, accompanied by swelling, pain, a feeling of heaviness in the legs, thrombophlebitis, periphlebitis, varicose dermatitis, pain and swelling after injuries (bruises, ligament damage).
Contraindications:
Hypersensitivity to the drug. Violation of the integrity of the skin. Children under 18 years of age (no experience of use).
with caution in chronic renal failure (long-term use).
Use during pregnancy and breastfeeding.
Pregnancy.
In preclinical studies, teratogenicity and fetotoxicity of drugs containing troxerutin were not noted. In the first trimester of pregnancy, the use of the drug Troxerutin is contraindicated due to the lack of experience in clinical use. In the second and third trimesters of pregnancy, the use of the drug Troxerutin is possible only if the expected benefit to the mother outweighs the potential risk to the child.
Breastfeeding period
There are no data on the penetration of troxerutin into breast milk. The drug Troxerutin should not be used during breastfeeding.
Directions for use and dosage:
Outwardly! A column of gel 4-5 cm long is applied in a thin layer to the affected areas and lightly rubbed in 3-4 times a day until completely absorbed. The daily dose should not exceed 20 cm of gel. If necessary, the gel can be applied under bandages or elastic stockings. The duration of treatment is no more than 10 days.
If the symptoms of the disease worsen or do not go away after 6-7 days of daily use of the drug, you should consult a doctor who will prescribe further treatment and determine the duration of the course of therapy.
Side effect:
In rare cases, allergic skin reactions are observed - urticaria, eczema, dermatitis. These symptoms disappear quickly after stopping treatment.
Overdose:
Cases of overdose with the recommended method of use of the drug are not known. If the drug is accidentally swallowed, a burning sensation in the mouth, salivation, nausea, and vomiting may occur. In this case, lavage of the oral cavity and stomach is indicated, and, if necessary, symptomatic treatment.
In case of contact with eyes, mucous membranes and open wounds, local irritation is observed - lacrimation, hyperemia, burning, pain. The gel is washed off with a large amount of distilled water or isotonic sodium chloride solution until the complete disappearance or significant reduction in the severity of these symptoms.
Interaction with drugs:
No information available.
Special instructions:
The gel is applied only to an undamaged surface.
Avoid contact with open wounds, eyes and mucous membranes!
In conditions characterized by increased vascular permeability (including scarlet fever, influenza, measles, allergic reactions), the gel is used in combination with ascorbic acid to enhance its effect.
Features of the action of the drug when first taken or when discontinued:
No information available.
Information about the possible effect of a medicinal product for medical use on the ability to drive vehicles and machinery:
Does not affect the ability to drive vehicles or operate moving machinery.
Storage conditions:
Store in a place protected from light at a temperature not exceeding 25°C. Keep out of the reach of children.
Shelf life: 2 years.
Do not use the drug after the expiration date indicated on the package.
Release form:
Gel for external use 2%.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in orange glass jars with a triangular rim and a lid that is tensioned with a sealing element.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in polymer jars complete with lids or in polyethylene terephthalate jars with closures.
Labels made of label or writing paper, or a self-adhesive label, are glued onto jars and cardboard boxes.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in aluminum tubes, coated with BF-2 varnish, with caps made of high-density polyethylene or in polymer tubes with polyethylene screw caps.
Each jar and tube, along with instructions for use, is placed in a cardboard pack.
Vacation conditions:
Available without a prescription.
How to take Troxerutin gel
The drug in the form of a gel is intended for local application. It should be applied to the problem area 2 times a day (morning and evening). The ointment should be distributed in a thin layer over the entire damaged area, without affecting healthy skin. You need to rub the product in with smooth massaging movements until the gel is completely absorbed.
The permissible dose depends on the size of the problem skin, but should not be more than 2 g. When the ointment is applied, a bandage should be applied to the surface of the skin.
The drug in the form of an ointment, regardless of the manufacturer, has a similar treatment regimen.
Analogues of Troxerutin
What is the cost of Troxerutin and its analogues? The price of the gel depends on the manufacturer. A Russian-made product will cost the patient 43 rubles, a Bulgarian product - from 59 to 111 rubles. Preparations for external use that additionally contain horse chestnut or shark oil are more expensive.
What can replace Troxerutin gel? The most common and popular analogues are:
- Troxevasin 2% - 221 rubles;
- Troxevasin Neo - 283 rubles;
- Troxevenol - 159 rubles.
An analysis of prices for drugs with similar effects proves that Troxerutin is the cheapest drug.
Contraindications
Contraindications include:
- hypersensitivity to the constituent substances of the drug;
- chronic gastritis in the acute stage;
- stomach ulcer;
- children under 15 years of age;
- lactation period;
- 1st trimester of pregnancy.
Use with caution in case of kidney problems (if long-term treatment is necessary).
special instructions
The drug in one of its forms can be used as part of a complex treatment. In case of vein thrombosis, parallel use of appropriate medications is allowed.
Shelf life: capsules – 5 years, gel – 2 years from the date of production.
Store in a dark place. Storage temperature for gel is 10-15 degrees, for capsules - 17-25 degrees.
Sold in any pharmacy without a doctor's prescription.
Manufacturers assure that the drug is absolutely harmless. It is prescribed to people who are overweight, as well as to the fair sex who wear high-heeled shoes. The medicine is recommended for people whose work requires constant standing.
To achieve maximum effect, you need to use gel and capsules from the same manufacturer. In the absence of contraindications, it is best to use Troxerutin together with ascorbic acid for a more pronounced effect.
Properties and composition of Troxerutin
Troxerutin is known as a complex drug that provides:
- vein protection;
- restoration of blood circulation;
- reduction of inflammation;
- elimination of edema;
- antioxidant effect.
Therefore, it can rightfully be called a gel for bruises, hematomas and contusions.
On the windows of pharmacies you can find the medicine Troxerutin produced by Russian and Bulgarian pharmacological companies. It comes in the form:
- gel for external use;
- capsules for internal use.
Troxerutin is the active component of both. This is a substance of plant origin, a flavonoid. There are only 2 grams of it in 100 g of gel, and 300 mg in one capsule. The gel is packaged in aluminum tubes of 40 g, capsules - in blisters and cardboard packages of 50 pieces.
A gel is usually used to treat bruises. It costs much less, and it has fewer side effects. Excipients of the gel are carbomer, benzalkonium chloride, sodium hydroxide solution, disodium edetate, water. They create the structure of the drug, thanks to which it is easily absorbed and reliably transports the active component into the affected tissues.
