Bloating, heaviness and colic in the abdomen are often associated with the active release of gas, the molecules of which put pressure on the gastrointestinal tract and cause discomfort. To quickly relieve symptoms, use effective remedies, for example, Sub Simplex. The drug only comes into physical contact with gas bubbles and does not react chemically. Thanks to this, it can be used at any age, including given to newborns.
Pharmacological properties of the drug Sab simplex
The active component of the drug Sab Simplex is simethicone - a stable surfactant polymethylsiloxane. It reduces the surface tension of gas bubbles formed in the contents of the stomach and intestinal mucus and causes their destruction. The released gases are absorbed by the intestinal wall or removed by intestinal peristalsis. Simethicone removes foam physically, does not enter into chemical reactions and is chemically inert. Simethicone is not absorbed when taken orally and is excreted unchanged.
"Sub Simplex" for newborns: composition, description
The drug is a carminative drug based on the active ingredient called simethicone. Available in the form of a viscous white emulsion. Aroma with notes of raspberry and vanilla. Along with simethicone, it contains a number of auxiliary components - flavorings, sorbic acid, sodium cyclamate and others.
"Sab Simplex" helps reduce the formation of gases in the gastrointestinal tract and removes them, thereby eliminating the symptoms of bloating and flatulence in adults and children. It acts only physically - it reduces the surface tension of gas bubbles, which leads to their destruction. As a result, gases are absorbed by the intestinal wall and leave the abdominal cavity.
The active ingredient is not absorbed by the body because it is chemically inert (does not react with other substances). Therefore, it is excreted in the feces in the same form as it was received.
The product is produced in plastic bottles with a volume of 30 ml or more. They can be stored at normal room temperature, away from direct sunlight. Access for children is excluded. The general shelf life is 3 years from the date of production - after this period the product cannot be used.
Use of the drug Sab Simplex
Sub Simplex is best taken with or after meals and, if necessary, before bed. The drug can be given to newborns before feeding using a small spoon. Shake the bottle vigorously before use. In order for the suspension to begin to flow out of the pipette, the bottle must be turned upside down and tapped on the bottom. The duration of use depends on the clinical dynamics. Sub Simplex can be taken for a long time if necessary. Use in preparation for diagnostic examinations of the abdominal organs is facilitated if the pipette is removed from the bottle. If there are complaints related to excessive gas formation Newborns and children of the first year of life Add 15 drops (0.6 ml) of Sub Simplex to each bottle of baby food. The drug mixes well with other liquids, such as milk. If symptoms are present, use during each feeding. Children aged 1 year - 6 years: Prescribe 15 drops (0.6 ml) during or after each meal. If necessary, 15 drops can be taken before bed. Children over 6 years of age and adults School-age children are prescribed 20-30 drops (0.8-1.2 ml), adults - 30-45 drops (1.3-1.8 ml). In the indicated doses, the drug is taken every 4–6 hours; if necessary, the dose can be increased. The duration of treatment depends on the severity of flatulence. If necessary, Sub Simplex can be used for several days or even several weeks. Preparing for an x-ray examination The day before the examination, take 3–6 teaspoons (15–30 ml) of Sab Simplex in the evening. Preparation for ultrasound examination Take 3 teaspoons (15 ml) of Sab Simplex in the evening the day before the examination and 3 teaspoons 3 hours before the examination. Preparation for endoscopic examination Before endoscopy, take –1 teaspoon (2.5–5 ml) of Sab Simplex. During the examination, an additional few milliliters of Sub Simplex suspension can be injected through the endoscope to remove foam bubbles. Intoxication with detergents The dose depends on the severity of intoxication. The minimum recommended dose of Sab Simplex is 1 teaspoon (5 ml).
Contraindications and side effects
The product should not be used if there is individual hypersensitivity to the active ingredient or to any excipient. Also, administration is excluded in the presence of intestinal obstruction.
Use during pregnancy (any stage) and breastfeeding is permitted. It is also allowed for use by newborns and infants at any age. “Samplex itself” can also be used by patients suffering from diabetes (regardless of the type and stage of development of the disease), since the emulsion does not contain sugars.
In most cases, no side effects are observed. But sometimes a skin rash, itching, and redness may appear. In this case, the treatment is suspended and a doctor is consulted for a possible change in therapy. There have been no cases of overdose - the drug is safe and does not pose a threat to health.
Sab simplex 30ml suspension for oral administration
Latin name
Sab Simplex
Active ingredient: Simethicone
Compound
The composition of the drug Sab Simplex includes 6.919 grams of simethicone.
Additional ingredients: carbomer, sodium citrate dihydrate, hypromellose, citric acid monohydrate, raspberry flavor, sodium saccharinate, vanilla flavor, sodium benzoate, sorbic acid, polyglycostearyl esters, sodium cyclamate, water.
Release form
A slightly viscous white emulsion with a vanilla-raspberry scent. During storage it may turn yellow. 30 ml of emulsion in a bottle with a drip device. One bottle in a cardboard pack.
pharmachologic effect
Carminative action.
Pharmacodynamics and pharmacokinetics
The main component of the drug is simethicone, which is a surface-active stable polymethyloxane. It changes the surface tension of gas bubbles formed in the stomach and provokes their destruction. The released gases are absorbed by the intestinal wall or evacuated by peristalsis.
Removes foam physically, does not react chemically and is inert.
It is not absorbed when taken orally and is excreted unchanged by the intestines.
Indications for use
Symptomatic therapy for complaints from the digestive tract associated with increased gas formation.
Increased gas formation due to surgical interventions.
An auxiliary tool for diagnostic examinations of the abdominal organs and in preparation for fibrogastroduodenoscopy.
Detergent poisoning.
Contraindications
The suspension should not be used if there is hypersensitivity to simethicone or to any other component of the drug, or intestinal obstruction.
Side effects
Adverse reactions when using the drug are usually not observed, but itching, skin rash, and hyperemia may potentially occur.
Instructions for use (Method and dosage)
The instructions for Sub Simplex prescribe taking the drug before bed, orally, during or after meals. Before taking, shake the container with the suspension. In order for the suspension to begin to come out of the pipette, the bottle must be turned over and tapped on the bottom. Sab Simplex mixes well with various liquids.
With increased gas formation:
children 7-15 years old are prescribed 21-30 drops of the drug;
children 1-6 years old - 15 drops;
adult patients are recommended - 31-45 drops.
The indicated doses should be taken every 5-6 hours, and if necessary they can be increased.
How to give to a newborn?
For newborns and infants, add 15 drops of the drug to each bottle of the mixture. The product is also allowed to be given to newborns in a small spoon before feeding.
If necessary, Sub Simplex can be taken for a long time.
Preparing for gastrointestinal tract examinations
To prepare for radiography, 16–30 ml of the drug is needed the day before the study in the evening.
To prepare for an ultrasound, you need to take 15 ml of the drug the day before the examination, in the evening and another 15 ml before the examination.
To prepare for endoscopy, you should take 2.5–5 ml of the medicine. During the examination, it is additionally necessary to inject a few more milliliters of Sub Simplex through the endoscope.
When treating intoxication with detergents, the dose and regimen depends on the clinical picture of the disease and is usually 5 ml.
Overdose
No similar cases have been recorded.
Interaction
There is no information about the specifics of interaction with other drugs.
Terms of sale
Over the counter.
Storage conditions
Keep away from children. Store at room temperature.
Best before date
3 years.
Instructions for use "Sub Simplex"
The drug is taken before bedtime during meals or after that. First, the bottle is inverted and shaken several times until the suspension becomes homogeneous. Then it is turned over and tapped on the bottom.
The dosage depends on the patient's age. If there are signs of increased gas formation, it is necessary to give (one-time amount indicated):
- children from 1 year to 6 years – 15 drops;
- children from 7 to 15 years old – 21-30 drops;
- adults – from 31 to 45 drops.
The drug is taken 2-3 times a day with an interval of at least 5 hours until the symptoms of bloating completely disappear. If necessary, the indicated quantities may be slightly increased.
For newborns, the drug is given in the amount of 15 drops. Can be mixed into a bottle or given in a spoon. The aroma of vanilla and raspberries is pleasant, so taking the medicine does not cause discomfort.
The drug is also taken in preparation for various types of studies:
- X-ray – take 16-30 ml the night before.
- Ultrasound - 15 ml the day before the procedure, then in the evening and another 15 ml immediately before the start.
- Endoscopy - take 3-5 ml on the eve of the procedure. Also, during endoscopy, another 3-5 ml is taken in consultation with the doctor.
To treat the effects of taking detergents, take 5 ml. However, the dosage may be increased if the symptoms are pronounced and do not go away.
Sab® simplex
Shake the bottle well before use. To dispense drops, hold the bottle upside down and gently tap the bottom of the bottle with your finger.
For complaints related to infant colic and excessive gas formation
Dosage
The indicated dose should be taken every 4 to 6 hours. If necessary, the frequency of administration can be increased for adults and children aged 6 years and older.
| Age | Single dose | Maximum daily dose |
| Newborns | 10 drops (0.4 ml) | 4×10 drops (1.6 ml) |
| Infants (>4 weeks to <12 months) | 15 drops (0.6 ml) | 6×15 drops (3.6 ml) |
| Children (> 12 months to < 6 years) | 15 drops (0.6 ml) | 23 x 15 drops (14 ml) |
| Children (>6 years to <18 years) | from 20 to 30 drops (from 0.8 to 1.2 ml) | Not applicable |
| Adults | from 30 to 45 drops (from 1.2 to 1.8 ml) | Not applicable |
The drug Sab® Simplex contains sodium benzoate as a preservative.
Mode of application
Newborns and infants (> 4 weeks to < 12 months):
Sub® Simplex can be added to a feeding bottle. Sub® Simplex mixes easily with other liquids, such as milk.
Sub® Simplex can be given with a small spoon before feeding, including before breastfeeding.
The use of Sab® Simplex in premature infants is not recommended.
Children (>12 months to <18 years) and adults:
Sub® Simplex is best taken during or after meals and, if necessary, before bed.
The duration of use depends on the dynamics of complaints. If symptoms persist or worsen, you should consult your doctor.
In preparation for diagnostic studies (radiography, ultrasound, etc.)
To prepare for x-rays, the day before the examination in the evening, take 3-6 teaspoons (15-30 ml) of Sub® Simplex.
When preparing for an ultrasound, it is recommended to take 3 teaspoons (15 ml) of Sub® Simplex in the evening the day before the examination and 3 teaspoons (15 ml) approximately 3 hours before the examination.
In preparation for esophagogastroduodenoscopy
Before endoscopy, you should take 1/2 - 1 teaspoon (2.5 - 5 ml) of Sab® Simplex. During the examination, an additional few milliliters of Sub® Simplex suspension can be injected through the endoscope to remove foam bubbles that cause irritation.
In case of acute poisoning with detergents containing tensides
The dose depends on the severity of intoxication. The recommended minimum dose of Sab® Simplex is 1 teaspoon (5 ml).
The use of the drug for the indications listed above (x-ray examination, ultrasound examination, esophagogastroduodenoscopy, detergent poisoning) is facilitated if the drip device is removed from the bottle.
