Getting vitamins from food is not always possible in daily quantities, since this requires a varied, balanced diet. In addition, many beneficial substances are destroyed when heated. To compensate for the deficiency of vitamins and minerals, special complexes are taken, including Vitrum.
Compound
One tablet contains:
- retinol acetate (vitamin A) and betacarotene - 6000 IU (corresponds to the content of retinol a acetate - 2 mg, betacarotene - 112 mcg);
- alpha-tocopherol acetate (vitamin E) - 45 IU (45 mg);
- phytomenadione (vitamin K1) - 10 mcg;
- cholecalciferol (vitamin D3) - 400 IU (10 mcg);
- ascorbic acid (vitamin C) - 60 mg;
- thiamine hydrochloride (vitamin B1) - 1.5 mg;
- pyridoxine hydrochloride (vitamin B6) - 3 mg;
- riboflavin (vitamin B2) - 1.7 mg;
- pantothenic acid (in the form of calcium pantothenate - vitamin B5 ) - 10 mg;
- nicotinamide (vitamin PP) - 20 mg;
- cyanocobalamin (vitamin B12) - 25 mcg;
- folic acid (vitamin B9) - 200 mcg;
- calcium ( in the form of calcium hydrogen phosphate ) - 200 mg;
- biotin (vitamin H) - 30 mcg;
- magnesium (in the form of magnesium oxide ) -100 mg;
- potassium (in the form of potassium chloride ) - 80 mg;
- phosphorus (in the form of calcium hydrogen phosphate ) - 48 mg;
- copper (in the form of copper oxide ) - 2 mg;
- iron (in the form of ferrous fumarate ) - 9 mg;
- manganese (in the form of manganese sulfate ) - 2.5 mg;
- zinc (in the form of zinc oxide ) - 15 mg;
- iodine (in the form of potassium iodide ) - 150 mcg;
- selenium (in the form of sodium selenate ) - 20 mcg;
- boron (in the form of sodium borate ) - 150 mcg;
- nickel (in the form of nickel sulfate ) - 5 mcg;
- chromium (in the form of chromium chloride ) - 100 mcg;
- molybdenum (in the form of sodium molybdate ) - 25 mcg;
- vanadium (in the form of sodium metavanadate ) - 10 mcg;
- chloride (in the form of potassium chloride ) - 72 mg;
- silicon (in the form of sodium metasilicate ) - 10 mcg.
Vitrum Century Forte includes :
- tin (in the form of tin chloride ) - 5 mcg;
- lutein - 100 mcg;
- leaves of the Ginkgo Biloba in powder form - 20 mg.
The following are used as excipients: microcrystalline cellulose, stearic acid, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate .
The shell contains: hypromellose, triacetin, titanium dioxide , black dye, sunset yellow dye, charming red dye.
Vitrum® century
Manufacturer: UNIPHARM, Inc. (USA)
◊ tab., cover. film-coated: 30, 60, 100, 120 or 130 pcs. Reg. No.: P N013531/01
Clinical and pharmacological group:
Multivitamins with macro- and microelements
Release form, composition and packaging
◊ Film-coated tablets
from light gray to dark gray, capsule-shaped, with a dividing line on one side; on a cross section - the kernel is light yellow, interspersed with darker or white color; A specific odor is allowed.
1 tab. | |
retinol acetate (Vit. A) and betacarotene | 6000 IU, |
which corresponds to the content of retinol acetate | 2 mg |
which corresponds to the betacarotene content | 112 mcg |
α-tocopherol acetate (Vit. E) | 45 IU (45 mg) |
colecalciferol (vit. D3) | 400 IU (10 mcg) |
phytomenadione (Vit. K1) | 10 mcg |
ascorbic acid (vit. C) | 60 mg |
thiamine hydrochloride (vit. B1) | 1.5 mg |
riboflavin (vit. B2) | 1.7 mg |
pantothenic acid (as calcium pantothenate) (vit. B5) | 10 mg |
pyridoxine hydrochloride (vit. B6) | 3 mg |
Nicotinamide (Vit.PP) | 20 mg |
folic acid (vit. Bc) | 200 mcg |
cyanocobalamin (vit. B12) | 25 mcg |
biotin (Vit. H) | 30 mcg |
potassium (in the form of potassium chloride) | 80 mg |
calcium (in the form of calcium hydrogen phosphate) | 200 mg |
magnesium (as magnesium oxide) | 100 mg |
phosphorus (in the form of calcium hydrogen phosphate) | 48 mg |
iron (as ferrous fumarate) | 9 mg |
copper (in the form of copper oxide) | 2 mg |
zinc (in the form of zinc oxide) | 15 mg |
manganese (as manganese sulfate) | 2.5 mg |
iodine (as potassium iodide) | 150 mcg |
molybdenum (as sodium molybdate) | 25 mcg |
Selenium (as sodium selenate) | 20 mcg |
chromium (in the form of chromium chloride) | 100 mcg |
nickel (in the form of nickel sulfate) | 5 mcg |
vanadium (as sodium metavanadate) | 10 mcg |
boron (as sodium borate) | 150 mcg |
chloride (in the form of potassium chloride) | 72 mg |
silicon (in the form of sodium metasilicate) | 10 mcg |
Excipients:
microcrystalline cellulose - 41.18 mg, stearic acid - 36.29 mg, colloidal silicon dioxide - 30 mg, croscarmellose sodium - 16.67 mg, magnesium stearate - 12 mg.
Shell composition:
hypromellose - 20.738 mg, triacetin - 0.003 mg, titanium dioxide - 9.2 mg, black dye (indigo carmine (E132), sunset yellow dye (E110), charming red dye (E129)) - 0.04 mg, sunset yellow dye (E110) - 0.015 mg, charming red dye (E129) - 0.001 mg.
30 pcs. — polyethylene bottles (1) — cardboard packs. 60 pcs. — polyethylene bottles (1) — cardboard packs. 100 pieces. — polyethylene bottles (1) — cardboard packs. 120 pcs. — polyethylene bottles (1) — cardboard packs. 130 pcs. — polyethylene bottles (1) — cardboard packs.
Description of the active components of the drug "Vitrum® Century"
pharmachologic effect
A combined preparation containing vitamins and minerals in specially selected doses that meet the needs of the body of people over 50 years of age.
Indications
Prevention of hypovitaminosis and lack of minerals in people over 50 years of age, including:
- during periods of intense mental and physical stress;
- during the period of recovery after illnesses;
- with insufficient and unbalanced nutrition.
Dosage regimen
Orally 1 tablet/day after meals. The course of taking the drug is 3-4 months. Repeated courses - on the recommendation of a doctor.
Side effect
Maybe:
allergic reactions to the components of the drug.
Contraindications
- age up to 50 years;
- hypersensitivity to the components of the drug.
Pregnancy and lactation
Consultation with a physician is recommended.
special instructions
Do not exceed the recommended dose.
Impact on the ability to drive vehicles and operate machinery
Does not affect the ability to drive vehicles or control other mechanisms.
Overdose
Symptoms:
nausea, weakness, gastrointestinal disorders.
Treatment:
activated carbon orally, gastric lavage, symptomatic therapy.
In case of overdose, consult a doctor.
Drug interactions
The drug contains iron and calcium and therefore delays the absorption in the intestine of antibiotics from the tetracycline group, as well as antimicrobial agents of fluoroquinolone derivatives.
Vitamin C enhances the effect and side effects of antimicrobial agents from the sulfonamide group.
Antacids containing aluminum, magnesium, calcium, and cholestyramine reduce iron absorption.
When thiazide diuretics are prescribed simultaneously, the likelihood of hypercalcemia (increased calcium levels in the blood) increases.
It is not recommended to use Vitrum® Centuri together with medications containing vitamins A and D, due to an increased risk of overdose of these vitamins.
Conditions for dispensing from pharmacies
The drug is approved for use as a means of OTC.
Storage conditions and periods
The drug should be stored out of the reach of children, in a dry place at a temperature of 10° to 30°C. Shelf life: 5 years.
Drug interactions
The drug contains iron and calcium and therefore delays the absorption in the intestine of antibiotics from the tetracycline group, as well as antimicrobial agents of fluoroquinolone derivatives.
Vitamin C enhances the effect and side effects of antimicrobial agents from the sulfonamide group.
Antacids containing aluminum, magnesium, calcium, and cholestyramine reduce iron absorption.
When thiazide diuretics are prescribed simultaneously, the likelihood of hypercalcemia (increased calcium levels in the blood) increases.
It is not recommended to use Vitrum® Centuri together with medications containing vitamins A and D, due to an increased risk of overdose of these vitamins.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Vitrum Centrum belongs to a group of drugs called multivitamins or multivitamin preparations. Contains all vitamins and minerals in doses required for older people over 50 years of age. Increases resistance to diseases common at this age, improves physical and mental performance. Reduces the risk of cancer and heart diseases, prevents premature aging.
- Vitamins A, E, C, beta-carotene, selenium, zinc, copper and manganese are antioxidants and protect cell elements, including chromosomes , from damage by oxygen radicals.
- Vitamin A in older people is responsible for T- and B-cell immunity , and also helps accelerate the synthesis of cytokines . Retinoic acid supports the activity of killer cells, which play a major role in antiviral and anticancer defense.
- Betacarotene is used in the body to build vitamin A and prevents damage to cell membranes by lipid peroxidation products.
- Ascorbic acid is a powerful antioxidant that increases the body's nonspecific resistance.
- Vitamin E is also a strong antioxidant, used in the biosynthesis of hemoglobin and proteins, and affects the condition of blood vessels.
- Selenium is converted in the body to glutadione peroxidase , which protects cells and tissues from organic hydroperoxides.
- Vitamins B1, B2 and B6 play an important role in normalizing protein, fat and carbohydrate metabolism.
- Vitamin B1 promotes the proper functioning of the biochemical processes of the nervous, endocrine and cardiovascular systems.
- Vitamin B2 is a component of flavin enzymes , which ensure tissue respiration and the formation of ATP in cells, as well as numerous energy-intensive redox processes.
- Vitamin B6 is involved in the metabolism of glycogen , amino acids , sphingoid bases and the production of neurotransmitters .
- Nicotinamide is a component of dehydrogenase proteins that transport hydrogen ions in cells.
- Pantothenic acid is involved in the processes of endothelial restoration and fatty acid metabolism.
- Vitamin B12 is needed for the production of nucleotides and the metabolism of fatty acids, and the passage of methylation processes in cells. Together with folic acid, it plays an important role in maintaining hematological and neurological homeostasis.
- Folic acid is a coenzyme of molecules responsible for the synthesis and destruction of amino acids and nucleic acids. Consumption of the required amount of folic acid is the prevention of a number of cancer diseases, in particular cancer of the colon and rectum, lungs, esophagus, and stomach.
- Vitamin K1 is used to prevent osteoporosis , has anti-sclerotic and anti-inflammatory effects, regulates blood glucose levels, and improves the clinical picture of Alzheimer's disease .
- Vitamin D , copper, calcium, magnesium, manganese, zinc and boron play a large role in the prevention of osteoporosis (brittle bones).
- Iodine is an important component of thyroid , which support the proper functioning of many metabolic processes and maintain immunity.
- Iron is part of hemoglobin a , which carries oxygen to organs and tissues and cellular respiration, and many other proteins ( myoglobin, flavoproteins, transferrin, lactoferrin, hemosiderin ). Improves appetite, stimulates recovery and healing processes.
- Molybdenum is involved in the construction of sulfite kinase, xanth oxidase and aldehyde oxidase molecules, which are responsible for the destruction of some amino acids and heterocyclic bases ( purines and pyrimidines ). These processes affect the neurological status of the body.
- Chromium enhances the action of insulin .
- Nickel in the composition of special proteins regulates iron metabolism.
- Silicon is a building material for bones and collagen .
Vitrum Century Forte additionally contains:
- lutein – prevents vision loss and improves its sharpness;
- powder of the leaves of the Ginkgo Biloba is a proven remedy that increases cognitive functions (memory, numeracy, attention, and others) in older people;
- tin – improves recovery processes, regulates the activity of flavin enzymes , an integral part of the gastrin .
Pharmacokinetics
Pharmacokinetic studies of the drug have not been conducted.
Vitamins "Vitrum": composition, description
The drug is a complex of vitamins and beneficial micro- and macroelements involved in all metabolic processes of the body. The composition includes the following substances:
- vitamin A;
- vitamin E;
- vitamin PP;
- vitamins B1, B2, B6, B12;
- vitamin C;
- vitamin D3;
- magnesium;
- iron;
- calcium;
- zinc;
- phosphorus;
- manganese;
- iodine;
- chromium;
- vanadium;
- chromium;
- molybdenum.
The drug is produced in the form of tablets, which must be stored under normal room conditions: temperature no more than 25 degrees, moderate humidity (up to 60%), out of direct sunlight. The general shelf life is 5 years from the date of production.
Contraindications
Hypersensitivity to the drug and its components; hypercalcemia, hypermagnesemia, hypercalciuria, nephrolithiasis, active pulmonary tuberculosis history of sarcoidosis hypervitaminosis A, E and D , thrombophlebitis , fructose intolerance, gout , impaired copper or iron metabolism, severe renal dysfunction, hyperuricemia, erythremia, chronic cardiac failure , thyrotoxicosis , stomach or duodenal ulcer (possible increase in acidity), joint use of retinoids, selenium .
special instructions
The Vitrum vitamin complex is relatively safe, but some patients should take it with caution. The drug can cause harm to health in the presence of the following pathologies:
- chronic pancreatitis;
- diabetes mellitus of both types;
- neoplasms of various nature;
- cholelithiasis;
- pathologies of the digestive organs (stomach, duodenum, liver).
If women took large amounts of vitamin A (dosage from 10,000 IU), the course should be stopped. Further planning for conception is allowed after at least 6 months, since an excess of the vitamin can lead to problems with fetal development.
"Vitrum" contains a balanced composition of vitamins in the required daily dosage. Therefore, it is not worth taking other complexes in parallel. The drug does not affect reaction or concentration, so it can be taken daily by drivers and other workers whose activities involve the need to react quickly and make accurate decisions.
Side effects
- From the immune system: hypersensitivity , including anaphylaxis , Quincke's edema , fever in people with allergies.
- From the skin: rash, urticaria , redness of the skin, itching.
- From the gastrointestinal tract: nausea, dyspepsia, abdominal pain, belching, diarrhea , constipation, increased acidity of gastric juice, heartburn.
- From the central nervous system: dizziness, headache, excitability, drowsiness.
With long-term use in large doses, the following may appear: irritation of the digestive tract mucosa, hypercalcemia, paresthesia, hyperuricemia, hyperglycemia, renal dysfunction, temporary increase in the activity of liver enzymes and alkaline phosphatase , dry skin, seborrheic rash, hair loss.
Interaction
Since Vitrum Centuri contains iron and calcium, the absorption of tetracycline antibiotics and fluoroquinolones . Ascorbic acid enhances the effects of sulfonamides . Antacids , including magnesium, aluminum, calcium, iron absorption . Iron and silver supplements reduce the bioavailability of Vitamin E. Folic acid activates the metabolism of phenytoin .
Analogs
Level 4 ATX code matches:
Vitacap
Glutamevit
Bio-Max
Menopace
Lavita
Wellman
Teravit
Gerovital
Kaltsinova
Pregnakea
Oligovit
Multi-Tabs Intensive
Multi-Tabs Junior
Multi-Tabs Perinatal
Multi-Tabs Teen
Multi-Tabs Classic
Multi-Tabs Baby
Special Dragee Merz
Pregnavite
Complivit Trimester
Analogs of the drug are vitamin complexes of similar or identical composition: Vitrum Prenatal , Multimax Kinder , Multimax Prenatal, Oligovit, Supervit and others.
Indications for use
The product is used as a biological food additive. Main indications for use:
- vitamin deficiency in one or more vitamins;
- prevention of hypovitaminosis and deficiency of micro- and macroelements;
- recovery period after operations, long-term illnesses;
- period of seasonal diseases - ARVI and others;
- period of forced diet;
- prevention of weakening of the body against the background of severe stress and psycho-emotional tension.
Vitrum Centuri price, where to buy
In Russia, the average price of Vitrum Centuri Forte (30 tablets) is close to 415 rubles, Vitrum Centuri -380 rubles; in Ukraine 79 and 70 hryvnia, respectively.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
Pharmacy Dialogue
- Vitrum Centuri plus (tab.pl.vol. No. 30)Eagle Nutritionals
555 rub. order
show more
PaniPharmacy
- Vitrum Centuri tab.
p/o No. 30, Unipharm 143 UAH. order
show more
Vitrum Plus tablets No. 60
Name
Vitrum Plus.
Release form
Pills.
Dosage
1455 mg.
pharmachologic effect
Biologically active food supplement, contains a complex of multivitamins and minerals. Reduces the risk of developing hypovitaminosis and lack of minerals. Helps increase the body's defenses during the period of recovery after various diseases, injuries, surgeries and during surges of seasonal diseases.
Indications for use
As a dietary supplement to food: - to reduce the risk of developing hypovitaminosis and lack of minerals; — during the period of recovery after various diseases, injuries, operations and during surges of seasonal diseases.
Directions for use and doses
Adults: 1 tablet/day, with meals. Duration of treatment: 2-3 weeks. If necessary, the dose can be repeated after a month.
Contraindications
Individual intolerance to product components; pregnancy; lactation.
Compound
Calcium phosphate dibasic anhydrous, magnesium oxide, carrier microcrystalline cellulose, stabilizer stearic acid, potassium chloride, vitamin C (ascorbic acid), ferric fumarate, vitamin E (D-alpha-tocopherol acetate), carrier magnesium salt of stearic acid, tablet shell Opadry II white (hydroxypropyl methylcellulose stabilizer, titanium dioxide dye, polydextrose carrier, anti-caking agent talc, maltodextrin, medium chain triglycerides), croscarmellose sodium stabilizer, silicon dioxide stabilizer, vitamin PP (niacinamide (nicotinamide)), zinc oxide, vitamin B5 (calcium D-pantothenate) , vitamin A (retinol acetate), manganese sulfate, folic acid, vitamin D3 (colecalciferol), D-biotin, vitamin B6 (pyridoxine hydrochloride), vitamin K1 (phytomenadione), copper oxide, chromium chloride, vitamin B1 (thiamine mononitrate), vitamin B2 (riboflavin), potassium iodide, sodium selenate, sodium molybdate, sodium metavanadate, vitamin B12 (cyanocobalamin).
Storage conditions
The product should be stored out of the reach of children at a temperature of 15°C to 25°C and a relative humidity of no higher than 60%. Shelf life: 2 years.
Buy Vitrum Plus tab. p/capt.ob. 1455 mg±5% No. 60 in pharmacy
Price for Vitrum Plus tab. p/capt.ob. 1455 mg±5% №60
Instructions for use for Vitrum Plus tab. p/capt.ob. 1455 mg±5% №60