Betaserc: instructions for use, indications, price, reviews from doctors and on forums, analogues

Has restrictions during pregnancy

Prohibited during breastfeeding

Prohibited for children

Allowed for older people

Allowed for liver problems

Allowed for kidney problems

Betaserc is a histaminergic drug that acts on the nerve fibers of the system and affects the H3 receptor of the vestibular peripheral nerve. The drug normalizes the conduction of impulses in the vestibular receptor in parts of the brain. The result of this effect is a decrease in dizziness and severe nausea, the absence of vomiting and a decrease in extraneous sounds in the ears.

Mechanism of action of Betaserc

Betaserc is an American-made drug that is an antagonist of the H1 and NZ receptors of the vestibular nucleus of the nervous system centers. The drug restores the functionality of the vestibular center after undergoing neurectomy. Reduces the severity of symptoms in Vertigo pathology and Meniere's syndrome.

The medication is used for Meniere's syndrome with severe symptoms:

dizziness, which leads to severe nausea and vomiting;
decreased hearing quality;
extraneous noise in the ears;
vertigo.

Contraindications for use in therapy are an allergy to the components in the drug, as well as age under 18 years due to the unknown danger of the drug in children.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

An artificial analogue of histamine . The effect of betahistine has not been fully studied. There are only a number of hypotheses confirmed by clinical data:

active substance – partial stimulator of H1-histamine receptors and blocker of H3-histamine receptors of the vestibular centers of the nervous system; improves histamine metabolism and its release due to the above properties;
betahistine increases blood circulation in the inner ear, relaxing vascular sphincters in this area, and also enhances microcirculation in the brain;
betahistine stimulates restoration of vestibular function after vestibular neurectomy in animals and humans;
dose-dependently reduces the generation of impulses in neurons of the vestibular nuclei.

The therapeutic effect of betahistine was demonstrated in patients with Meniere's syndrome and vestibular vertigo , which was expressed by a decrease in the severity and frequency of dizziness .

Pharmacokinetics

When taken orally, the active substance is actively absorbed from the intestine and is almost completely transformed to form a derivative of 2-pyridylacetic acid. The content of betahistine in the blood is low.

Concomitant food intake may slow down the absorption of betahistine. Reaction with blood proteins does not reach the 5% barrier. The maximum concentration of 2-pyridylacetic acid in the blood occurs 1 hour after consumption. The half-life is approximately 3 and a half hours.

The metabolite is actively evacuated in the urine. Excretion of betahistine itself through the kidneys or intestines is negligible.

Other popular analogues in composition

There are analogues of Betaserc, which are similar or identical in composition to the original medication, and are most prescribed for the treatment of diseases associated with vestibular disorders. A list of the most popular analogues is presented below.

Vestibo

The mechanism of action of betahistine in the drug Vestibo is aimed at improving microcirculation in the inner ear and increasing blood flow in the cerebral vessels. Betahistine accelerates the process of restoration of the functional duties of the vestibular system after undergoing neurectomy. This process is characterized by an increase in the metabolic reaction and the release of histamine compounds.

The properties of Vestibo enhance the therapeutic effect in the treatment of Meniere's pathology, as well as headaches and dizziness. The main component, when taken orally, is quickly absorbed by the digestive organs.

The maximum level of betahistine metabolites in the blood is 1 hour after taking the tablet. The half-life of the main substance is 3.5 hours. The medication is excreted through feces and urine.

The drug is prescribed for Meniere's disease with severe symptoms of dizziness, vomiting with severe nausea, as well as hearing loss and a sharp decrease in the quality of hearing. The daily dosage of the drug is 24-48 mg taken in 3 doses.

The effectiveness of treatment with Vestibo

The procedure for taking the medication should be distributed over equal time intervals. Vestibo is contraindicated if you are allergic to the components of the drug, as well as with pheochromocytoma.

Westinorm

Vestinorm is available only in tablet form. The active ingredient is betahistine. Vestinorm is used as part of the complex treatment of Meniere's pathology. It is also used to relieve symptoms of dizziness with uncontrollable nausea and vomiting.

The following pathologies are indicators for prescription:

insufficiency of the vertebrobasilar artery;
encephalopathy of traumatic etiology;
neuritis of the vestibular type;
atherosclerosis of cerebral arteries;
postoperative period of neurosurgical operations;
field of ophthalmological operations.

Vestinorm is not prescribed in case of sensitivity to the components, as well as in case of relapse of peptic ulcers and pheochromocytoma.

Vestinorm does not have a sedative effect, so you can drive without fear. If you take it with antihistamines, then the effect of Vestinorm is reduced by more than 50%. During pregnancy and lactation, the drug is prescribed extremely rarely and only under the supervision of a gynecologist.

The drug is taken three times a day, 8 mg during or after meals. If there is a base, then the dosage is doubled. The dosage and duration of the medication course is determined individually for each patient.

Vazoserk Duo

This drug is an analogue of Betaserc (24 mg of active ingredient in each tablet) and is used in the treatment of vestibular disorders.

Vasoserc acts on histamine receptors H1 and H3 in the nuclei of the vestibular brain centers. The agonistic effect on the receptors of the arteries of the inner part of the ear promotes the process of local vasodilation, which improves blood flow.

By influencing the neurons of the vestibular nerve centers, the drug improves capillary permeability and microcirculation of the cerebral arteries, and also promotes the release of histamine. The drug does not have sedative properties and does not affect the blood pressure index.

The drug can also be used for Parkinson's disease.

Indications for use of Betaserc

Indications for use of Betaserc:

Meniere's disease;
vertebrobasilar insufficiency , atherosclerosis of the cerebral arteries , post-traumatic encephalopathy (as a component of complex therapy);
syndromes characterized by tinnitus, increasing hearing loss, dizziness , including hydrops of the inner ear , labyrinthine and vestibular disorders, labyrinthitis , vestibular neuritis, benign positional vertigo.

Analogues in other forms

It is not always convenient for patients to take medicine in tablet form, so manufacturers have developed medications to relieve symptoms of abnormalities in the functioning of the vestibular nerve in the form of a solution for internal use.

Akuver

The drug acts on the neurons of the receptor nuclei of the vestibular centers, which increases capillary permeability, as well as a greater release of histamine. The drug helps restore normal cerebral microcirculation, as well as all metabolic processes in fluids throughout the microvasculature. Transmission in neurons with the help of serotonin also increases.

Acuver is available in the form of a solution. Prescribed for Meniere's pathology, which is accompanied by severe dizziness and nausea, which activates the gag reflex. Contraindications for taking Akuvera are sensitivity to the components, pheochromocytoma.

Meniere's syndrome

When you press the pump with the medicine, 8 mg of the active component enters the body with a stream. Standard therapy is 2-3 times a day, 1 press of the pump in the medicine. The dosage can be doubled (2 presses at a time). Medication course – from 14 days to 90 days. The therapeutic effect occurs with long-term use (longer than 14 days).

Avertid

Avertid is available in solution for oral use. Indications for use are symptoms of Meniere's syndrome with severe dizziness and headache, as well as nausea, which provokes severe vomiting.

The drug is contraindicated for the following diseases:

pheochromocytoma;
sensitivity to ingredients in the medicine;
the body's reaction to ethanol.

Pheochromocytoma

In the first trimester of pregnancy, the medication is strictly prohibited, and in the 2nd and 3rd trimester - only under the supervision of a gynecologist. During lactation, it is necessary to transfer the newborn to artificial feeding before taking the medication.

The prescribed dosage should be taken during meals or after finishing meals three times a day. Using a syringe, you need to measure the required amount of medicine and take it undiluted or diluted (in 50-100 ml of water). 1 ml of solution contains 8 mg of the main component.

Betaserc tablets, instructions for use (Method and dosage)

The medicine is prescribed to be taken orally with meals. The dosage is selected individually, taking into account the response to therapy.

The daily dose for adults is usually 24-48 mg, divided into 2-3 doses. The 16 mg or 24 mg tablet is easy to split. To do this, place the dosage form on a hard surface with the notch facing up and press firmly on it with your finger.

Sometimes the drug shows its effect only after 2-3 weeks of treatment, and a confident therapeutic effect develops after several months of constant use. No dosage adjustment is required in elderly patients.

The cheapest similar products

Analogues from domestic manufacturing companies are several times cheaper than the original and its foreign analogues, but they do not differ in quality and efficiency. A list of cheap analogues of Betaserc is presented below.

Betaver

Betaver - a medication with the active component betahistine is an angioprotector that is able to correct microcirculation processes in the brain. Betaver belongs to the pharmacological group of histaminomimetics. The localization of the effect of the drug is receptors in the ear and in the vestibular centers of the brain.

Betahistine, in addition to affecting the capillaries in the ear, affects the processes of blood microcirculation in capillaries throughout the body, reducing their permeability. Under the influence of the medication, blood flow in the basilar artery improves.

Medication is prescribed for the following microcirculation disorders:

dizziness;
Meniere's disease;
headache, nausea, which provokes a gag reflex;
prevention of severe dizziness.

Betaver is not prescribed for:

pregnancy and lactation;
allergies to betahistine and other components;
ulcerative pathology in the digestive organs;
cardiac and bronchial asthma.

Cardiac asthma

The tablets are taken orally during meals. The permissible dosage per day of Betaver (8 mg) is from 3 to 6 tablets, and the drug with a dosage of 16 mg is 1 tablet three times a day.

The patient can feel the therapeutic effect after taking several tablets, and a stable, lasting effect after taking it for two weeks. The dosage of the medication and the duration of therapy are determined individually and depend on the disease and the stage of its progression.

Betagistine

Betahistine is an analogue of histamine. The drug is a weak H1 agonist but a potent H3 antagonist. The drug improves microcircular processes, both in the ear, current and vestibular parts of the brain. The drug inhibits receptors of the lateral as well as medial nuclei.

Indications for use are:

dizziness;
Meniere's disease;
tinnitus, as well as nausea, causing vomiting.

Betagistine

Take the medication orally while eating. You need to take the tablets with the required amount of water. Betahistine should be taken 2-3 times a day. The dosage of the medication per day is 24 mg. If necessary, the dosage can be doubled.

A stable therapeutic effect occurs 2-3 weeks after the start of therapy. Contraindications are:

pregnancy and breastfeeding;
allergy to components;
pheochromocytoma.

Betaserc's analogs

Level 4 ATX code matches:
Betagis

Which is better: Betaserc or Betahistine?

Betahistine and the described drug are analogues with an identical active component. Their indications and contraindications are also the same. The choice should be made based on economic feasibility.

Betaserk or Vestibo – which is better?

Vestibo is a cheaper analogue of Betaserc with almost the same composition. The choice between these drugs should be made for reasons of economic feasibility.

Tagista or Betaserk – which is better?

Tagista is the Russian analogue of Betaserk. The main difference is the price: Tagista rightfully takes the place of the most affordable medicine containing betahistine.

Substitutes for therapeutic effect

Betahistine in the drug is not always suitable for patients. Then the doctor can select a medicine with a different active ingredient, but an identical mechanism of action.

Aviamarin

This medication belongs to the pharmacological group of medications that are prescribed for disorders of the functioning of the vestibular system.

The main active medical component is dimenhydrinate, which is a histamine H1 receptor blocker. The medication belongs to the ethanolamine group and has the following properties:

sedative;
antiemetic;
anticholinergic.

The drug calms the centers of the nerve plexuses, relieves severe symptoms of Meniere's disease (head pain and dizziness), and also, with the help of an antiemetic effect, vomiting receptors are inhibited, and the synthesis of the gastric and salivary glands is inhibited. The medication is effectively used to prevent seasickness (motion sickness).

You should not take the drug if:

allergies to ingredients in the composition;
renal and liver failure;
dermatoses;
epilepsy.

Epilepsy

It is also strictly forbidden to give tablets to children under 2 years of age. Young children are allowed to take Aviomarin at the rate of 5 mg per kilogram of weight. This calculation is up to 6 years, and after this age 50 mg are prescribed at intervals of 4-6 hours. Adult patients over 14 years of age are prescribed 50 to 100 mg 3-4 times a day. The maximum daily dosage is 400 mg. The tablets should be taken without being tied to meals.

Tablets for motion sickness and nausea

These tablets have an orange tint, round and flat shape. On one edge of the dragee there is an engraving “APO 50”, and on the other there are 2 marks.

Therapeutic direction of these medications:

elimination of nausea, as well as vomiting during motion sickness in transport, intoxication with medications, after anesthesia. The drug is not effective for relieving symptoms of nausea after radiation and chemotherapy;
Meniere's disease and severe symptoms of dizziness.

Contraindications to taking pills are the following pathologies:

glaucoma and high intracranial pressure;
porphyria and prostatic hyperplasia;
eclampsia and asthma;
liver and kidney failure;
epilepsy and Parkinson's disease.

A tablet (50 mg) should be taken orally half an hour to an hour before a long trip, and you can also take the medicine after 4-6 hours, but not more than 8 tablets per day. Children over 6 years old - half a tablet (25 mg) every 6-8 hours, but no more than 3 tablets per day.

Betaserk price, where to buy

The price of Betaserc 24 mg No. 20 on average in Russia is about 500 rubles, and the drug with a dosage of 16 mg No. 30 is 600 rubles.

In Ukraine, the price range is wide: a package of medicine with a dosage of 16 mg No. 30 can be bought for about 400 hryvnia.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

LuxPharma* special offer

Betaserc tablet.
24 mg 20 pcs 950 rub. order

ZdravCity

Betaserc tab. 24 mg No. 60 JSC Veropharm
RUB 1,245 order
Betaserc tab. 16mg No. 30AO Veropharm
606 rub. order
Betaserc tab. 24mg No. 20AO Veropharm
RUR 538 order
Betaserc Long tablets 48 mg 28 pcs. JSC Veropharm
RUB 1,145 order
Betaserc Long tablets 48 mg 56 pcs. JSC Veropharm
1900 rub. order

Pharmacy Dialogue

Betaserc tablets 24 mg No. 20Abbot/Veropharm
RUR 559 order
Betaserc tablets 16 mg No. 30Abbot/Veropharm
RUR 627 order
Betaserc Long tablets 48 mg No. 28 Veropharm
1122 rub. order
Betaserc tablets 24 mg No. 60Abbot/Veropharm
RUB 1,269 order
Betaserc (tab. 16 mg No. 30) Abbot/Veropharm
RUR 607 order

Pharmacy24

Betaserc 8 mg N30 tablets Abbott Healthcare SAS., France
376 UAH order
Betaserc 16mg N30 tablets Mylan Laboratories SAS, France
423 UAH. order

PaniPharmacy

Betaserc tablets Betaserc tablets 24 mg No. 20 France, Mylan Lab.
418 UAH. order
Betaserc tablets Betaserc tablets 16 mg No. 30 France, Mylan Lab.
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429 UAH. order
Betaserc tablets Betaserc tablets 8 mg No. 30 France, Mylan Lab.
432 UAH. order