Trental: instructions for use, price, indications for use, reviews on forums and analogues

Trental is a peripheral vasodilator. The medication is produced in solution for injections and in tablets based on the active ingredient - pentoxifylline. There are many structural analogues of Trental based on pentoxifylline on the pharmacological market.

Trental is used to treat the following disorders:

encephalopathy of atherosclerotic origin;
ischemic stroke;
disruption of blood flow in peripheral arteries due to the development of systemic atherosclerosis;
diabetic type angiopathy;
ulcers of diabetic or atherosclerotic etiology;
gangrene;
Raynaud's syndrome
varicose veins;
improper blood flow in the eyes, which can cause inflammation of the optic nerve and organ failure;
ear diseases.

Trental is not prescribed for the following reasons:

allergy to the composition;
excessive bleeding and predisposition to it;
hemorrhagic stroke and hemorrhage in the eye;
acute phase of myocardial infarction;
ulcerative destruction in the digestive tract;
hemorrhages.

The medicine is also not prescribed to pregnant women and during lactation. Adverse reactions from the use of Trental:

neurological disorders - dizziness and pain in the head, irritability and anxiety, convulsions and tremors of the arms and legs, hallucinations and paresthesia, disturbance of sleep rhythm;
dermatological reactions - urticaria and hyperemia of the epidermis, flushing of the face, swelling and fragility of the nail plate;
reactions of the digestive tract - diarrhea, nausea and vomiting, cholecystitis, hepatitis;
cardiac disorders - tachycardia and blood pressure fluctuations, edema in the periphery, arrhythmia and angina.

Compound

Trental tablets contain 100 mg of the active ingredient pentoxifylline and additional substances: silicon dioxide, starch, talc, lactose and magnesium stearate.
The shell consists of talc, titanium dioxide, sodium hydroxide, methacrylic acid copolymer, as well as macrogol 8000. The infusion solution concentrate in 1 ml contains 20 mg of the active substance pentoxifylline and additional substances: injection water and sodium chloride.

Long-acting tablets Trental 400 contain 400 mg of the active ingredient pentoxifylline and additional substances: magnesium stearate, povidone, talc, hyaetellose. The shell contains: benzyl alcohol, talc, macrogol 6000, hypromellose, titanium dioxide.

Answers to frequently asked questions

Answers to the most pressing and common questions from patients are given.

Is Trental an antibiotic or not?
No, the drug belongs to the group of drugs for improving cerebral and peripheral circulation (vasodilating agents).
What is the difference between Trental 100 or 400?
Both drugs belong to the same group and have similar effects. They differ in the amount of the active substance - pentoxifylline: in the first case it contains 100 mg, in the second - 4 times more. A low-dose drug is more often prescribed to patients with low blood pressure or a risk of low blood pressure during treatment.

Pharmacodynamics and pharmacokinetics

The drug inhibits phosphodiesterase, has a positive effect on the rheological properties of blood, improves microcirculation, increases the concentration of ATP in erythrocytes and the concentration of cAMP in platelets. At the same time, under the influence of the medication, there is a saturation of the energy potential, which leads to a decrease in peripheral vascular resistance, vasodilation, an increase in VO and SV without a significant effect on the pulse. By expanding the lumen of the coronary arteries, pentoxifylline increases the flow of oxygen to myocardial tissues, providing an antianginal effect.

The drug improves blood oxygenation by expanding the lumen of the blood vessels of the lungs. Trental increases the tone of the respiratory muscles: the diaphragm and intercostal muscles. When administered intravenously, it enhances collateral blood circulation and increases the volume of blood per unit section. The drug has a positive effect on the bioelectrical activity of the brain, increasing the concentration of ATP. Trental 400 increases the elasticity of red blood cells, promotes platelet disaggregation, and reduces blood viscosity. In areas with impaired blood supply, pentoxifylline improves microcirculation. For intermittent claudication and occlusive lesions of the peripheral arteries, the medication eliminates pain at rest, relieves night cramps in the calf muscles, and helps lengthen the walking distance.

The active substance is well absorbed and metabolized. The half-life for tablets is about one and a half hours, for the solution - just over an hour. It is mainly excreted through the kidneys (more than 90 percent), and also with feces to a lesser extent.

pharmachologic effect

The drug Trental belongs to the group of vasodilating agents, including pentoxifylline. Has the following actions:

reducing blood viscosity, improving its fluidity;
reducing the adhesion of leukocytes to the walls of blood vessels, the adhesion of platelets and red blood cells;
slight relaxation and expansion of the coronary vessels;
weak improvement in the contractility of the heart muscle;
improving cerebral circulation and reducing the severity of symptoms (Trental is better for the brain at a dosage of 400 mg);
disappearance of pain at rest, elimination of night cramps and contraction of the calf muscles, lengthening of the walking distance in pathologies of the peripheral circulatory system.

A frequent question from patients is whether Trental thins the blood or not. Yes, it reduces blood viscosity and improves flow through veins and arteries. To prevent bleeding and adverse reactions when taken together with anticoagulants that perform a similar effect, regular monitoring of blood clotting parameters is necessary.

Indications for use of Trental

What does the medicine help with?

Indications for use of the drug are peripheral circulatory disorders:

obliterating endarteritis;
intermittent claudication in diabetic angiopathy .

The drug is effective in treating tissue trophic disorders:

frostbite;
gangrene;
varicose veins;
postthrombotic syndrome;
trophic ulcers of the leg.

What other indications for the use of Trental exist? The medication is used:

for Raynaud's disease ;
for cerebral atherosclerosis ;
cerebrovascular accident;
with neuroinfection of viral origin;
dyscirculatory encephalopathy;
after myocardial infarction ;
with ischemic heart disease;
with impotence of vascular origin;
bronchial asthma;
COPD;
otosclerosis;
acute disturbances of blood supply in the choroid and retina.

Actovegin or Trental

Actovegin is a drug in ampoules (for intravenous and intramuscular administration) and tablets. Improves trophic nutrition, activates metabolic processes in tissues, stimulates regeneration. Normalizes the absorption and supply of oxygen to tissues. Used to treat impaired peripheral circulation and complications, cognitive disorders, diabetic polyneuropathy.

Trental is also produced in tablets and ampoules. Used to treat diseases of peripheral and cerebral circulation. Dilates blood vessels, improves the properties of blood cells, cerebral circulation.

Which is better, Actovegin or Trental, depends on the indications and is determined by the attending physician.

Contraindications

The drug is not used for porphyria , acute myocardial infarction , intolerance to xanthine derivatives, breastfeeding, massive bleeding, hemorrhages in the retina, or hemorrhagic stroke .

Intravenous infusions are unacceptable in case of uncontrolled arterial hypotension , with severe atherosclerosis of the cerebral and coronary arteries, and with arrhythmias .

For peptic ulcers of the digestive system , for CHF, lability of blood pressure, for insufficiency of the renal and hepatic systems, after surgical interventions, pentoxifylline is prescribed with caution.

Trental is not used during pregnancy.

When to use analogue?

Trental is not well tolerated by all patients. It has a lot of side effects and contraindications. Some patients, on the recommendation of a doctor, switch to analogues in the following cases:

the presence of negative reactions of the body;
high cost, unaffordable for the patient;
desire to use a different form of release, for example, instead of injection tablets, so that the effect occurs faster.

Curantil, Cavinton, Actovegin, Pentoxifylline, Mexidol are used as a substitute. Medicines have contraindications and side effects. Therefore, they are used with the permission of a doctor, after passing tests. Otherwise, negative consequences are possible that will worsen the patient’s well-being due to decreased cerebral circulation or other pathologies.

If the doctor has prescribed an analogue of Trental, stop using it. It is impossible to take 2 drugs with identical effects at the same time. Since Trental increases blood circulation, its analogue will enhance the effect. There will be a deterioration in health with the risk of internal bleeding.

When you start taking the substitute, it is recommended to retake laboratory and instrumental tests to confirm the positive dynamics.

The new medicine is used in a strict dosage. It is not recommended to take a break from treatment. Circulatory disorders are a serious pathology. It leads to serious consequences if the cause is not eliminated in a timely manner.

Actovegin and its influence

Actovegin is a medicine containing a deproteinized hemoderivative of calf blood. This product is natural based and does not contain chemical components. Due to the active ingredients, the pharmacological effect is ensured:

elimination of oxygen deficiency due to distribution through tissues through the blood while improving rheological properties;
increased metabolism, increasing the regeneration of damaged cells;
protection of neurons from hypoxia, toxic effects, and other damaging factors;
improvement of the rheological properties of blood at the systemic level and in the area of microcirculation.

Due to the effect on the body, indications for use are formed. The medicine is prescribed for cognitive impairment, causing deterioration of mental ability, dementia. It is used for disorders of peripheral and central circulation. It helps patients improve the condition of blood vessels with diabetic polyneuropathy.

Side effects include local and systemic allergic reactions, myalgia.

The drug is contraindicated for patients with individual intolerance, heart failure in the stage of decompensation, pulmonary edema, urination problems, severe body edema, and minors. Actovegin is allowed during pregnancy. It improves blood circulation in the placenta. This prevents fetal hypoxia.

Why is Pentoxifylline needed?

Pentoxifylline is a domestic drug with the active substance of the same name. More often prescribed as an injection for intravenous or intramuscular administration. The medicine has the following effects:

improvement of microcirculation in central and peripheral vessels;
protection of the vascular endothelium from damage;
reduction of viscosity with improvement of rheological properties of blood;
destruction of aggregated platelets, improvement of red blood cell elasticity;
with a long course of use - improvement in heart rate;
expansion of the coronary arteries with increased blood flow to the heart muscle along with oxygen;
normalization of collateral circulation;
improving brain function with the prevention of hypoxia.

The drug has many indications for use. It is prescribed for disorders of peripheral circulation with congestion, impaired functionality of the vessels of the lower extremities. The drug is applicable for atherosclerosis, encephalopathy, neuroinfection, coronary heart disease, myocardial infarction, angiopathy, circulatory disorders in the retina, degeneration of cerebral vessels, chronic diseases of the bronchial tree. The drug can cause neurological disorders, dermatitis, digestive disorders, cardiovascular abnormalities, deterioration of hematopoiesis, and allergies.

Why is Mexidol better?

Mexidol is a medicine containing ethylmethylhydroxypyridine succinate. Produced in ampoules containing a solution for intravenous administration. The active substance enters directly into the systemic bloodstream, bypassing physiological barriers. Therefore, a person receives the entire dose of the drug, and the effect is observed quickly. The drug causes the following effects on the body:

protective effect against hypoxia;
preventing cell destruction;
nootropic effect;
elimination of seizures;
improving human activity, preventing the influence of various stresses;
increased metabolism with accelerated regeneration of damaged tissues;
normalization of lipid metabolism;
prevention of platelet aggregation, hemolysis.

The drug is indicated for use in cases of cerebrovascular accident, traumatic brain injury, encephalopathy, atherosclerosis, neurological disorders, glaucoma, alcohol withdrawal, acute purulent-inflammatory processes in the abdominal cavity. It can be used in combination with other medications.

The only side effects include nausea, dry mucous membranes, drowsiness, and allergies.

The drug has contraindications. It is not recommended to take it for liver and kidney diseases in the acute stage. The drug is not prescribed for individual intolerance.

Efficiency of Curantil

Curantil is a medicine containing dipyridamole. The drug is prescribed in tablets, but there is an injection form. It causes the following pharmacological action:

myotropic effect;
inhibition of platelet aggregation;
improvement of blood microcirculation;
dilatation of arterioles in the coronary blood flow system;
strengthening immune function by stimulating the production of interferon and leukocytes in the blood.

The drug is indicated for use in cases of deterioration of blood circulation, stroke, heart attack, encephalopathy, ischemic heart disease, thrombosis, thromboembolism, placental insufficiency. It is often used to prevent frequent ARVI and influenza. The following side effects are identified:

dyspeptic reactions, impaired stool formation;
thrombocytopenia with risk of bleeding;
neurological disorders with dizziness, headache, noise in the ears and head;
local and systemic allergic reactions;
arthritis, myalgia;
rhinitis, ear congestion.

The drug is contraindicated in case of heart attack or stroke in the acute stage, angina pectoris, atherosclerosis of the coronary arteries, heart failure, hypotension, collapse, severe cardiac arrhythmias, renal and liver failure. It is not recommended for use in patients at risk of bleeding. Before prescribing, the doctor checks whether the patient has individual intolerance.

Treatment with Cavinton

Cavinton - tablets containing vinpocetine. The composition contains auxiliary components that the doctor should take into account if the patient has allergic reactions. When the active substance enters the body, it causes the following pharmacodynamics:

improvement of cerebral blood flow;
stimulation of metabolism in the brain with protection of nerve cells from destruction;
improvement of the rheological properties of blood.

In neurology, the drug is indicated for mental disorders, vertebrobasilar insufficiency, and dementia. In ophthalmology, the drug is prescribed for chronic diseases that cause retinal hypoxia. In otolaryngology - used to eliminate hearing loss and tinnitus. The following side effects are identified:

deterioration of hematopoietic function;
diabetes mellitus, anorexia;
depression, migraine, tremor;
swelling of the optic nerve, redness of the conjunctiva;
local and systemic allergic reactions.

The medicine is contraindicated in case of individual intolerance to the components, pregnancy, lactation, or minors. It can be used for arrhythmia, but with caution. Overdose is possible with the development of adverse reactions described in the instructions for use. Treatment is carried out by gastric lavage and the use of sorbents. Use symptomatic therapy.

How does Flexital work?

Flexital is a product based on pentoxifylline. Available in tablets for oral use. Basics of pharmacodynamics:

improving the properties of red blood cells;
eliminating platelet aggregation with reducing the risk of thrombophlebitis, thrombosis;
suppression of fibrinogen formation;
myotropic, vasodilating effect;
improving blood circulation through vessels and capillaries;
slight dilatation of the coronary vessels.

The medicine is indicated for circulatory problems due to the development of atherosclerosis and diabetes mellitus. It is used for ischemia, encephalopathy, angioneuropathy, atrophic diseases, endarteritis, retinal pathologies, and hearing impairment. It is important that these diseases develop against the background of a violation of systemic or local blood flow.

There are many side effects. More often they develop due to improper use of the drug or the use of drugs in an excessive course. There are dyspeptic disorders, cardiovascular pathologies, neuralgia, allergies, cholecystitis and hepatitis, meningitis. Hypersalivation, conjunctivitis, scotoma, weight gain, and nasal congestion may develop.

The medicine is contraindicated in case of heart attack or stroke in the acute stage, massive bleeding, pregnancy and lactation. It is not recommended for use by patients under 18 years of age. If individual intolerance is observed, the medicine is not prescribed.

Side effects

Nervous system: convulsions, anxiety, dizziness, headache, sleep disturbances.

Subcutaneous fat, skin: increased fragility of nails, swelling, “flushes” of blood flow to the face, chest, hyperemia of the skin.

Digestive tract: cholestatic hepatitis , exacerbation of cholecystitis , intestinal atony , decreased appetite, dry mouth.

Side effects from the sensory organs: visual disturbances, scotoma .

Cardiovascular system: drop in blood pressure, progression of angina , cardialgia , arrhythmia , tachycardia .

Hemostasis system, hematopoietic organs: bleeding in the intestines, stomach, mucous membranes, skin, hypofibrinogenemia , pancytopenia , leukopenia , thrombocytopenia . Allergic reactions in the form of anaphylactic shock , urticaria , itching , angioedema , hyperemia of the skin. An increase in liver enzymes and alkaline phosphatase is also recorded.

Trental or Cavinton

Cavinton is a drug that improves cerebral blood flow and metabolism in the brain. Available in ampoules and three forms of tablets - regular, enhanced with the prefix forte (10 mg) and dispersible (Comforte). Prescribed to eliminate tinnitus, dizziness, headache, unsteadiness in gait associated with vascular disorders, and atherosclerosis.

Trental is used for the same purposes, and for other indications - circulatory disorders in the extremities.

Both drugs are prescription drugs produced by imported manufacturers. Improve blood flow and metabolism in tissues. Which is better depends on the desired therapeutic effects and indications.

Instructions for use of Trental (Method and dosage)

The drug is taken orally, and also administered intraarterially, intravenously, intramuscularly. The dose must be prescribed by a doctor.

For pathology of the renal system, the drug is prescribed at a dose of 50-70% of the standard dose.

Trental ampoules, instructions for use

Typically, 2 intravenous infusions are given in the morning and afternoon, 200-300 mg of the active substance together with a sodium chloride solution. Intravenous infusions are carried out slowly, 50 mg is administered over 10 minutes (together with 10 ml of sodium chloride), after which they switch to administering 100 mg on a dropper (together with 250 ml of sodium chloride, administered for at least an hour). The maximum dose per day can be 0.6 mg of active substance per 1 kg of person’s weight per hour.

Intramuscular injections are carried out deeply 2-3 times a day, 100-200 mg.

Parallel administration of oral forms of the drug is possible at a dose of 800-1200 mg per day for 2-3 doses. The initial dosage is 600 mg per day. If the dynamics are positive, the amount of pentoxifylline is reduced to 300 mg per day.

Trental tablets, instructions for use

Take 100 mg tablets orally with water, during or after meals, 3 times a day, gradually increasing the dose to 200 mg.

Instructions for use Trental 400

Typically take 1 tablet 3 times a day. The maximum dose you can take is 1200 mg of the active substance per 24 hours.

Generic tablets

There are generics of Trental in tablet form. This dosage form makes it easier to take the medication.

Chime

Curantil is a myotropic vasodilator that blocks platelet aggregation, which improves microcirculation in the cerebral arteries. The main component is dipyridamole, which has a vasodilating effect on the arterial membranes.

Curantil is used in the treatment of such diseases:

disturbance of blood flow in the cerebral arteries due to the development of ischemia;
encephalopathy;
myocardial ischemia, with aspirin intolerance;
thrombosis and thrombophlebitis;
disturbance of peripheral blood flow;
viral pathologies.

Also prescribed as a prophylaxis for thromboembolism after cardiac surgery and placental insufficiency. It is prohibited to use Curantil in therapy for these reasons:

allergy to medication;
acute form of heart attack;
hemorrhagic type stroke;
angina pectoris;
atherosclerosis of the cerebral and coronary arteries;
aortic stenosis;
collapse;
hypotension;
chronic lung pathologies;
hemorrhages;
ulcerative destruction in the digestive tract;
risks of bleeding.

The drug is prescribed to patients who are 12 years old at the time of treatment. Dosages and treatment regimen:

the dosage is prescribed based on the pathology and the stage of its progression - 3-9 tablets per day;
The daily dose should be divided into 3-4 doses.

The duration of the medication course is determined by the doctor personally for each patient.

Vazonite

Vazonite is produced in tablets with the main component – pentoxifylline. Tablets are prescribed for the following diseases:

angioneuropathy;
atherosclerotic and dyscirculatory encephalopathy;
disturbance of blood flow in parts of the brain of ischemic origin;
violation of microcirculation in the eyes;
impaired blood supply to the periphery due to the progression of diabetes, atherosclerosis;
hearing loss.

Vazonit is also prescribed for severe symptoms of microcirculation disorders in the brain regions of vascular etiology:

dizziness;
impaired memory quality;
decreased concentration and attentiveness.

It is prohibited to use Vazonit if:

allergies to medicinal composition;
internal severe bleeding;
cerebral hemorrhage;
bleeding into the eyeball;
acute phase of a heart attack;
pregnancy, breastfeeding and up to 18 years of age.

Prescribe with caution when:

atherosclerosis of cerebral and coronary arteries;
low blood pressure and disturbed myocardial rhythm;
liver and kidney dysfunctions;
ulcerative phenomena of the gastrointestinal tract;
risk of severe bleeding.

Vazonit is taken twice a day, 1 tablet. The integrity of the tablet film must not be destroyed. The maximum dosage of the drug in 24 hours is 3 tablets (1200 mg).

Bilobil

The herbal medicine Bilobil normalizes metabolism in cells, restores the properties of blood composition and improves microcirculation. By improving blood flow to parts of the brain, oxygen starvation of neurons is reduced, platelet aggregation is suspended, which prevents the formation of blood clots in intracerebral vessels

Bilobil expands the membranes of arterioles and capillaries, which restores blood movement in the periphery. The herbal medicine is prescribed for the following disorders in the blood flow system:

cognitive disorders in elderly patients, except for patients suffering from dementia, Parkinson's disease;
dizziness of vascular etiology;
vestibular rehabilitation and treatment of tinnitus.

Bilobil is not used in the treatment of patients:

with an allergy to a herbal medicine;
childhood.

According to the general treatment regimen, you need to take 1 capsule three times a day and drink 100 ml of water. It is not recommended to crush the capsule. The duration of taking capsules is prescribed by the doctor, but the average therapeutic course lasts 2-3 months.

Bilobil does not provoke adverse reactions if the patient does not exceed therapeutic dosages.

Agapurin

Agapurin is a therapeutic analogue of the drug Trental and is aimed at expanding the arterial membranes. Methylxanthine, when present in the drug, blocks the aggregation of platelet molecules and improves fibrinolysis, and also inhibits phosphodiesterase. With this action of the drug, the total peripheral resistance decreases and blood flow to the periphery and coronary vessels improves, which contributes to a greater supply of oxygen to the myocardium and neurons of the brain.

Agapurin is used in the treatment of such diseases:

encephalopathy;
stroke and ischemia;
disturbance of blood flow in the periphery during angiopathy;
obliterating atherosclerosis and endarteritis;
diabetes;
trophic destruction of tissues of the lower extremities due to venous insufficiency;
gangrene;
Raynaud's syndrome;
lack of blood flow to the eyes;
disturbances in the functioning of the inner ear.

Agapurin is not used for:

allergies to medications;
severe bleeding;
hemorrhage in the eye and brain;
hemorrhages;
heart attack and ulcerative disorders in the stomach;
pregnancy, breastfeeding and pediatrics.

Agapurin is used parenterally by intravenous administration and orally (tablets). The dosage is prescribed personally by the doctor, but there are standard dosages:

To administer the medicine using the drip method - 100-600 mg per 100-500 ml of Ringer's solution or sodium chloride. Frequent administration - 1-2 times a day.
Dosage of tablets per day – 1 (400 mg) tablet twice or thrice a day. The permissible maximum per day is 1200 mg.

Overdose

Manifested by tonic-clonic convulsions, agitation, drowsiness, tachycardia , fainting, decreased blood pressure, dizziness, weakness, vomiting “coffee grounds” and other signs of gastrointestinal bleeding .

Emergency gastric lavage, administration of enterosorbents, activated carbon , and syndromic therapy are required.

Interaction

According to the annotation, Trental enhances the effect of medications that affect blood clotting (thrombolytics, anticoagulants of direct and indirect effects), antibiotics ( cefotetan , Cefoperazone , cefamandole and other cephalosporins), valproic acid .

Pentoxifylline enhances the effect of oral hypoglycemic agents, insulin, and antihypertensive drugs. Cimetidine can increase the level of the drug in the blood and increase the severity of side effects. With the simultaneous use of other xanthines, excessive nervous excitement of patients is observed.

Trental or Detralex – which is better?

Detralex is a combined analogue based on diosmin and hesperidin. Refers to venotonic and venoprotective agents. The drug eliminates leg cramps, pain, a feeling of “fatigue,” bloating and heaviness of the lower extremities. Prescribed for varicose veins, venous trophic ulcers, swelling of the legs. Dispensed without a doctor's prescription.

Trental has a less pronounced effect on trophic ulcers and varicose veins. Can be prescribed together with Detralex.

It is difficult to determine which of the two drugs is better. The drugs belong to different groups and have different therapeutic effects.

special instructions

Monitoring of blood clotting is required during simultaneous therapy with anticoagulants.

Therapy with pentoxifylline is carried out under mandatory monitoring of blood pressure levels.

In patients with diabetes mellitus , the medication may cause hypoglycemia .

After surgical interventions, monitoring of hematocrit and hemoglobin levels is necessary.

In case of unstable and low blood pressure, the dosage of the drug is reduced.

There is no reliable data on the safety and effectiveness of Trental in children.

Inhalation of tobacco smoke causes a decrease in the therapeutic effectiveness of the drug.

During intravenous infusions, the patient should be in a supine position.

Efficiency of using analogues

Trental is a high-quality drug that causes a beneficial effect on the body. It enhances central and peripheral blood circulation. It is used for different categories of patients, but the drug has side effects. If they are observed in a patient, it is better to replace the drug with an analogue. The same effect will occur, but there will be no side effects.

To check whether the effect has arisen from the use of Tental analogues, a laboratory and instrumental examination is performed. It includes a general blood test, coagulogram, and leukemia study. As part of the instrumental examination, angiography is often prescribed. If the test results show an improvement in well-being, the analogue can be used further.

It is prohibited to use Trental analogs without a doctor's permission; they affect blood circulation and can therefore cause bleeding if used uncontrolled.

If there are positive dynamics, the patient’s well-being will gradually improve. Signs of cerebral hypoxia, disorders of central and peripheral circulation will be eliminated. The patient will no longer be lethargic, pale, and drowsy. Vigor and activity will appear. If there are signs of side effects when using an analogue, stop using it. Contact a doctor to check your well-being through an examination.

Trental's analogs

Level 4 ATC code matches:
Agapurin

Vazonite

Xanthinol nicotinate

Pentoxifylline

Analogues of Trental in tablets are the following drugs:

Agapurin
Vazonite
Pentilin
Pentoxifylline

Which is better: Trental or Pentoxifylline?

Pentoxifylline is the active ingredient in Trental, but there is also a medicine with the same name that costs much less. The action of both drugs is essentially the same.

Curantil or Trental - which is better?

Analogue Curantil is an imported medicine from the group of vasodilating, antiplatelet drugs. It is used as prescribed by a doctor and is dispensed from pharmacies according to a specially issued prescription. Contains the substance dipyridamole, which has the following therapeutic effects:

improvement of microcirculation;
inhibition of platelet adhesion and adhesion to the walls of blood vessels;
dilatation of arterioles;
increasing resistance to viral infections;
improvement of decreased interferon production.

It is impossible to say for sure which is better for atherosclerosis - Trental or Curantil. Medicines have a similar effect. Can be prescribed together according to indications.

Reviews about Trental

The drug works effectively, performing the tasks for which it is intended. However, side effects such as dizziness, nausea, insomnia are common. Often, when taking this medication, you experience a headache and high blood pressure.

Very effective, really improves microcirculation, used for diabetes. You can use Trental intravenously and in tablets of 100 and 400 mg of the active substance. Side effects are common. The fluidity of the blood from the Trental solution and tablets increases, which can cause hemorrhage in the eyes, so it is better to consult an ophthalmologist before use.

Reviews about the choice of Trental and its analogues

Reviews about Trental are positive from cardiologists, neurologists and neurosurgeons, as well as from patients. Everyone notes the fast and high effect of Trental, which significantly shortens the period of therapy:

Tkachenko R.P., neurologist: “Trental is a medication that has been used for many years to restore normal microcirculation in the brain and periphery. Among the analogues, it is worth noting Curantil and Vazonit, which are no different in effectiveness from Trental.”
Roman, 57 years old: “For obliterating atherosclerosis, the doctor prescribed Trental to me. I am now taking the 2nd six-month course. My progression has stopped and no new ulcers are appearing on my legs. Now the doctor says that I need to change the drug and prescribed Pentoxifylline. So far I don’t see any difference in the drugs - no side effects, no special improvements, but I’ve only been taking it for a week.”

Trental is the most popular and time-tested medication for restoring proper blood flow in the patient’s body. Only a doctor can prescribe Trental, as well as select cheap analogues.

Trental price, where to buy

The price of Trental in tablets 100 mg is about 500 rubles per pack of 60 pcs.

The price of Trental in ampoules of 5 ml is about 2000 rubles per pack of 5 pcs.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

LuxPharma* special offer

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