Ganaton is an imported drug for regulating intestinal motility. It is original and, when used in a course, eliminates pain, vomiting, nausea, and bloating.
To purchase the medicine you need a prescription from a doctor.
Analogues of Ganaton differ in composition and mechanism, list of indications and restrictions.
Ganaton - instructions for use
Ganaton is prescribed for the treatment of adults by a doctor. The standard dosage is 1 tablet three times a day. The course is determined individually.
The maximum clinically studied duration of therapy is 8 weeks.
Possible side effects of Ganaton:
- decrease in the number of blood cells - leukocytes, platelets;
- headache, dizziness, tremor - a condition characterized by involuntary muscle contractions or twitching;
- allergic skin reactions - itching, urticaria, redness;
- changes in laboratory parameters of liver tests;
- nausea, jaundice, adverse reactions from the gastrointestinal tract;
- gynecomastia – a person’s mammary gland becomes enlarged and prolactin levels increase.
To prevent side effects, you should follow your doctor's recommendations regarding the dosage and course of treatment with Ganaton. If a reaction occurs, visit a specialist again.
Is Ganaton an antibiotic or not? No, this is a medicine to enhance gastrointestinal motility and treat dysfunctional conditions.
How to take Ganaton - before or after meals
For sufficient effect and prevention of adverse reactions, Ganaton tablets are taken before meals .
The cheapest substitutes
Below are brief reviews of Ganaton analogues, which are cheaper but no less effective.
Domperidone
Domperidone is an antiemetic drug containing an active substance with the same name. The drug is indicated for the elimination of vomiting, hiccups, nausea in patients with:
- disorders of the gastroduodenal region;
- gastric hypotension;
- GERD.
Mechanism of prokinetic action of domperidone
The drug is also used to alleviate dyspeptic disorders associated with problems with gastric emptying. Domperidone is prescribed to patients suffering from vomiting of any etiology.
The medicine is prescribed to children from 2 years of age in the form of rectal suppositories. For patients weighing 20 to 30 kg, Domperidone is prescribed in the form of oral tablets. The dosage is 0.5 tablets twice a day. Children weighing more than 30 kg are prescribed 1 tablet 2 times a day.
The dosage of the drug for adult patients depends on the severity of symptoms. The usual starting dose is 10 mg 3 or 4 times daily. In case of severe nausea or profuse vomiting, it is allowed to double the amount of the drug used. The frequency of administration remains the same.
It is important to pay attention to the column with contraindications for taking Domperidone. So, it is not prescribed for:
- gastrointestinal bleeding;
- mechanical intestinal obstruction;
- pregnancy;
- gastric perforation;
- lactation;
- hypersensitivity to domperidone or auxiliary components of the drug.
The drug in tablet form is not prescribed to children weighing less than 20 kg. Domperidone differs from Ganaton primarily in its composition and cost. The dosage regimen and side effects of each drug also differ.
Metoclopramide
Metoclopramide is a medication belonging to the group of antiemetic drugs. The active substance of the drug (similar name) has the property of blocking dopamine and serotonin receptors. Relieves nausea, eliminates vomiting and gets rid of hiccups.
Pharmacological action of Metoclopramide
The main indications for the use of Metoclopramide include:
- intestinal atony or hypotension;
- vomiting;
- nausea;
- hiccups of various origins;
- severe symptoms caused by undergoing a course of radiation therapy;
- biliary dyskinesia;
- flatulence;
- GERD;
- worsened gastric or duodenal ulcer.
Note. Metoclopramide is also used in diagnostic procedures. In particular, it is prescribed to patients who are to undergo X-ray contrast studies of the intestines.
The medicine is prescribed for early toxicosis in pregnant women as an antiemetic. But it is taken only on the recommendation of a doctor and under his careful supervision. Metoclopramide is also a very effective medication that relieves migraines. In this case, it is recommended to combine it with analgesics.
The drug is contraindicated in patients with intestinal bleeding, gastric pyloric stenosis, pheochromocytoma, epilepsy, dyspepsia, etc. Metoclopramide is not prescribed to women during lactation. Adult patients are prescribed 10 mg 3 times a day. The maximum permissible daily dosage of the drug is 30 mg.
Analogues of Ganaton
The list of cheaper analogues is presented for informational purposes only. The drugs have different compositions and mechanisms of action, dispensing conditions, indications and contraindications. Many substitutes require a doctor's prescription.
Substitutes and analogues of Ganaton
| Analogue | Price, in rubles | Manufacturer country |
| Ganaton | 330-1260 | Japan |
| Itopra | 400-560 | Russia |
| Domperidone | 60-230 | Russia, Hungary |
| Nolpaza | 90-840 | Russia or Slovenia |
| Cerucal | 110-280 | Germany or Croatia |
| Itomed | 390-980 | Czech Republic |
| Omez | 70-240 | India |
| Duspatalin | 500-770 | France or Russia |
| De-Nol | 280-940 | Netherlands, Russia |
| Trimedat | 270-1680 | Korea or Russia |
| Motilium | 600-940 | France |
| Motilak | 290-440 | Russia |
Domperidone
Manufacturer: Teva (Hungary), Ozone (Russia)
Release form: tablets
Active ingredient: domperidone
Synonyms: Passazhiks, Motilium, Motilak, Motonium, Domstal, etc.
An inexpensive analogue of Ganaton, Domperidone, is available in 10 mg tablets and is available with a prescription. Take 3-4 times before meals. The drug also inhibits dopamine receptors and enhances gastrointestinal motility, accelerating gastric emptying. The main indication is relief of vomiting, nausea, and hiccups. Additionally used for a feeling of heaviness, abdominal pain, and other manifestations of dyspepsia.
Nolpaza
Manufacturer: KRKA, Russia or Slovenia
Release form: tablets
Active ingredient: pantoprazole
Synonyms: Sanpraz, Pantoprazole, Panum, Controloc, Crosacid, etc.
Nolpaza inhibits the proton pump and is produced in tablets. By influencing the enzyme, it reduces the secretion of hydrochloric acid, thereby reducing the time food remains in the stomach, preventing heartburn, abdominal pain, and sour belching.
The price of the analogue of Ganaton Nolpaza depends on the dosage and number of tablets and ranges from 90 to 840 rubles. To purchase, you need a prescription from a doctor.
Cerucal
Manufacturer: Merkle (Germany), Pliva (Croatia)
Release form: ampoules, tablets
Active ingredient: metoclopramide
Synonyms: Metoclopramide
The drug Cerucal blocks dopamine receptors and has an antiemetic effect. Thanks to the injection form, it can be used urgently.
Ganaton substitute Cerucal should not be used independently, without a doctor’s prescription, due to serious side effects - spasm of the facial muscles, dyskinesia, parkinsonism, etc.
Omez
Manufacturer: Dr. Reddy s, India
Release form: capsules
Active ingredient: omeprazole
Synonyms: Omeprazole, Losek Maps, Ultop, Orthanol, etc.
The drug inhibits the proton pump and reduces the secretion of hydrochloric acid. The analogue is used as an antiulcer agent in the treatment of heartburn.
The company Dr. Reddis also produces a complex medication Omez D - a combination of omeprazole and domperidone. The medicine reduces the production of hydrochloric acid, has an antiemetic effect, and improves gastrointestinal motility.
Both forms of analogs - Omez and Omez D are available with a doctor's prescription.
Duspatalin
Manufacturer: Mylan (France), Veropharm (Russia)
Release form: tablets, capsules
Active ingredient: mebeverine
Synonyms: Mebeverine, Sparex, Niaspam
If the actual question is what can replace Ganaton for intestinal pain, there is an original remedy called Duspatalin. The conditions for dispensing from a pharmacy depend on the form (capsules or tablets) and, accordingly, the dosage. The medicine is intended to relax the smooth muscles of the gastrointestinal tract and normalize intestinal motility.
De-Nol
Manufacturer: Astellas (Netherlands), R-PHARM or ZiO Zdorovye (Russia)
Release form: tablets
Active ingredient: bismuth tripotassium dicitrate
Synonyms: Bismuth tripotassium dicitrate, Ulcavis, Escape, Novobismol
The medicine De-Nol protects the gastric mucosa and heals erosions and ulcers on the surface. It has an antibacterial effect against the causative agent of gastritis and peptic ulcer Helicobacter pylori.
Dispensed freely, without a doctor's prescription.
Used in combination with antibiotics and proton pump inhibitors.
Cost of Ganaton and its analogues
The cost of Ganaton is 231 rubles. This is the minimum price that pharmacies offer today. The main analogues with prices are presented in the table.
| No. | Name of the drug | Cost (rubles) |
| 1. | Domperidone | 199 |
| 2. | Metoclopramide | 75 |
| 3. | Itomed | 348 |
| 4. | Itopra | 436 |
| 5. | Motilium | 450 |
| 6. | Cerucal | 170 |
| 7. | Zofran | 705 |
| 8. | Motilak | 305 |
Note. These are the average prices for Ganaton substitutes. It should be borne in mind that in some regions they may differ significantly, so the prices described above can only be used as a guide.
Ganaton or Itomed – which is better?
Manufacturer: Pro Honey, Czech Republic
Release form: tablets
Active ingredient: itopride
Itomed is an analogue of Ganaton in tablets of 40 and 100 pieces per package. The therapeutic effect is provided by the same active ingredient, in a dosage of 50 mg.
Medicines differ in manufacturer and price. Itomed is produced in the Czech Republic, the cost is up to 20% lower. Ganaton is an original, researched Japanese drug. The advantage is that it is packaged in 10, 40 and 70 tablets.
Reviews from doctors about the drug Ganaton and the analogue Itomed are positive. What to choose is individual, depends on personal preferences, financial capabilities, and the severity of the condition.
How can I replace the medicine Ganaton?
The drug does not always help to quickly restore intestinal motility and eliminate discomfort in the abdomen. If Ganaton is inactive, doctors select an analogue. The need to replace the medication also arises due to the high price. Patients choose cheap analogues, which are no weaker in terms of pharmacological properties and mechanism of action in the body.
Synonyms of the drug
Medicines with the same active ingredients, but different names and manufacturers, are called synonyms. Like Ganaton, they restore intestinal motility, increase the tone of the lower esophageal sphincter, and eliminate nausea and vomiting. Brief characteristics of medications popular for dyspepsia:
| Name | Compound | Mode of application | Contraindications | Side effects | Price, rubles |
| Itopra | Itopride hydrochloride. | 1 table each 3 times/day before meals. |
|
| 350–450 |
| Itomed | Itopride hydrochloride. | 50 mg (1 tablet) 3 times a day. The maximum dosage is 150 mg/day. |
|
| 390 |
Russian analogues of Ganaton
Domestic-produced intestinal motility stimulants act no weaker than expensive imported drugs. Patient reviews of Russian analogues are positive, the main thing is compliance with dosages and medical prescriptions. Brief characteristics of popular treatments:
| Name | Compound | Mode of application | Contraindications | Side effects | Price, rubles |
| Motilak | Domperidone. | 1 table each 3 times/day 30 minutes before meals. |
|
| 290 |
| Passazhiks | Domperidone. | Chronic disorders: 1 table. 3 times/day 30 minutes before meals. Acute conditions: 2 tables. 3–4 times/day. |
|
| 130 |
Cheap drug substitutes
According to the instructions, the medications presented below will normalize the function of the digestive tract just as quickly as Genaton’s expensive analogues. Generics are sold without a prescription and are more affordable:
| Name | Active ingredient | Mode of application | Contraindications | Side effects | Price, rubles |
| Domperidone | Domperidone. | 1 table each 3 times/day 30 minutes before meals. In acute cases, the single dosage is increased to 2 tablets. 3–4 times/day. |
|
| 60 |
| Domrid | Domperidone. | For nausea and vomiting, 1 tablet is prescribed. 3–4 times/day. The course of treatment is 2 days. |
| Disorders of the nervous, endocrine, cardiovascular systems, gastrointestinal tract, vision and skin. | 35 |
| Domidon | Domperidone. | 1-2 tables each. (10–20 mg) 3 times/day or before bedtime. |
|
| 60 |
| Motorix | Domperidone. | Patients over 12 years old with a body weight of 35 kg or more: 1-2 tablets. 3 times/day 30 minutes before meals. |
|
| 50–120 |
Imported analogues
Expensive stimulants of intestinal motility act more gently than Ganaton tablets. According to reviews from doctors and patients, they are less likely to cause side effects and are well tolerated by the body. Brief characteristics:
| Name | Active ingredient | Mode of application | Contraindications | Side effects | Price, rubles |
| Motillium (Belgium, England) | Domperidone. |
|
|
| 250 |
| Brulium Lingvatabs (Belgium) | Domperidone. |
| Disorders of the nervous, urinary, endocrine systems, gastrointestinal tract, and skin. | 200–250 | |
| Motilium Lingual (England) | Domperidone. | 1 table each 3 times/day for 30 minutes. before meals. |
|
| 150–300 |
Ganaton or Trimedat
Manufacturer: Valenta Pharm (Russia) or Dae Han New Pharm (Korea)
Release form: tablets
Active ingredient: trimebutine
Synonyms: Neobutin, Neobutin retard, Trimedat forte
Trimedat is used for reflux esophagitis and dyspeptic symptoms.
The instructions indicate the following indications:
- impaired intestinal motility;
- diarrhea or constipation;
- epigastric pain;
- heartburn;
- bloating, etc.
Ganaton is also used for reflux gastritis and esophagitis, when digestion is disrupted and food is thrown into the esophagus. The drug has an antiemetic effect and improves intestinal motility.
Which is better depends on the individual. The drugs have different mechanisms of action and different active ingredients. Ganaton is used in the treatment of adults, Trimedat is approved in pediatrics from 3 years of age.
Drugs with similar therapeutic effects
You can replace Ganaton not only with the previously discussed drugs. The medications described below are no less effective for vomiting and other dyspeptic disorders.
Motilium
The drug contains domperidone 10 mg per tablet. Belongs to the group of stimulants of intestinal motility. It is used to relieve dyspeptic symptoms - nausea and vomiting.
Indications for the use of Motilium
The main difference between Motilium and Ganaton is not so much its composition as its contraindications for use. So, the medicine in question is categorically unacceptable to take if:
- prolactinoma;
- disorders of the kidneys or liver;
- prolonged cardiac conduction interval;
- treatment of various pathologies using ketoconazole, erythromycin, etc.
It is not recommended for women to take the pills during pregnancy and lactation.
In the latter case, if the medicine is nevertheless prescribed by the attending physician, it is necessary to abstain from breastfeeding for the entire period of therapy. Motilium is taken 1 pc. 3 times/day. This dosage is established for adult patients and children over 12 years of age.
Cerucal
The active ingredient is metoclopramide. Tablets for oral administration and solution for injection. Inhibits the gag reflex and normalizes the tone of the intestinal muscles.
The drug is effective for heartburn, nausea and other dyspeptic disorders. Tablets are also prescribed for gastric paresis caused by diabetes mellitus. The medicine can be prescribed to children from 3 years of age. The medication is also prescribed in the 1st trimester of pregnancy to stop vomiting caused by toxicosis.
Schemes for using Cerucal
Adult patients are prescribed Cerucal tablet 3-4 times a day. For children over 3 years of age, the dosage is calculated in the following way: from 0.1 to 0.5 mg per kilogram of weight. The full course of therapy can last for 1-2 months.
Zofran
Zofran is an imported (Italian) drug containing ondansetron in the amount of 4, 8 or 16 mg in 1 tablet, or 2 mg in 1 ml of injection solution.
Ondansetron belongs to the group of selective serotonin 5HT3 receptor blockers. The exact mechanism of action of the drug has not been fully studied, but it is reliably known that it has a pronounced antiemetic effect.
The drug, unlike the previously discussed generics of Ganaton, is used primarily in oncological practice. It is used to treat vomiting and nausea in patients taking cytostatic chemotherapy drugs.
Zofran is also prescribed to patients undergoing radiation therapy. Prevention of vomiting and nausea with the help of this medication is also carried out in patients who have recently undergone surgery under general anesthesia. In the postoperative period, Zofran is used mainly in the form of rectal suppositories.
Directions for use: The tablets must be swallowed whole with a sufficient amount of liquid. Take 1 tablet 1-2 times a day. It is necessary to take into account that the amount of the active component may vary, so the dosage of the medication is determined exclusively by the attending physician.
Zofran tablets are strictly contraindicated for pregnant patients, women during lactation, and children under 18 years of age. The syrup is not prescribed to children under 2 years of age.
Zofran has many differences from Ganaton. This includes the composition, some indications and contraindications for use, price, as well as features of use. It is strictly not recommended to buy this medicine without consulting your doctor.
Motilak
Motilak is a tablet preparation containing domperidone. Tablets can be intended either for oral administration or for resorption (this option is most suitable for heartburn).
Indications and contraindications for taking the drug are the same as for Motilium. It is recommended to take 1 tablet three times a day. The medicine should be taken 30 minutes before meals.
Motilak
The tablet must be swallowed without chewing. But the medicine for resorption should be in the oral cavity until completely dissolved. Motilak is prescribed with extreme caution to patients during lactation, as well as to patients with liver failure.
Ganaton or Motilium - which is better?
Manufacturer: Janssen-Cilag, France
Release form: tablets, syrup
Active ingredient: domperidone
Synonyms: Passazhiks, Domperidone, Motilak, Motonium
Ganaton's analog Motilium is an antiemetic. Additionally, it regulates the motility of the gastrointestinal tract and is prescribed for reflux, a condition when, after food enters the esophagus, it is thrown back. As a result, the patient experiences heartburn, belching, nausea, and vomiting.
Ganaton has a different mechanism and is also used for GERD.
Both drugs are prescription drugs. Which is better depends on the patient’s condition, indications, contraindications, financial capabilities, and cause of the disease. The analogue of Ganaton Motilium is approved in pediatrics.
Composition and pharmacological action of the drug Ganaton
The drug belongs to the pharmacological group of drugs used to stimulate intestinal motility. The therapeutic effect is provided by the active substances. The active component, itopride hydrochloride, acts on the upper parts of the gastrointestinal tract and accelerates the removal of food from the stomach. In addition, it relieves attacks of nausea and vomiting. Excipients:
- lactose;
- carmellose;
- magnesium stearate;
- anhydrous silicic acid;
- corn starch;
- hypromellose;
- macrogol;
- carnauba wax;
- titanium dioxide.
When administered orally, Ganaton is quickly absorbed from the digestive tract and evenly enters the internal organs and systems. Concomitant food intake does not reduce the degree of adsorption of itopride hydrochloride. The drug is metabolized in the liver. Decomposition products are excreted by the kidneys. The half-life is 6 hours.
Ganaton or Itopra
Manufacturer: Obolensk Pharmaceutical Enterprise, Russia
Release form: tablets
Active ingredient: itopride
Itopra is an analogue cheaper than Ganaton, which is its generic. This means that the drug has the same composition, indications, and contraindications.
Ganaton is an original medicine that has many clinical trials. On their basis, instructions for use were created, the frequency of side effects and drug interactions was studied.
Both drugs are high quality. However, the Russian cheap analogue of Ganaton Itopr has no clinical studies, bioavailability, frequency of adverse reactions and effectiveness are unknown.
