Pyrantel suspension for oral use 250mg/5ml 15ml No.1

Pirantel

Pyrantel is a drug that helps get rid of helminths.
Effectively affects mature individuals of nematodes (roundworms) and those that are in an early stage of development. Registered in Ukraine. Indications for use:

• enterobiasis;
• ascariasis;
• necatoriasis;
• hookworm disease;
• trichostrongyllosis;
• trichocephalosis.

Safe for children if you follow the instructions for use. Well tolerated, side effects are rare. Available in the form of tablets and suspensions.

The price in Ukrainian pharmacies ranges from 30 to 70 UAH for suspension and from 140 to 180 UAH for tablets.

Pyrantel for worms: features of the drug

This drug has been successfully used for more than 50 years in the fight against helminths.

The drug works like this: when it enters the body and encounters parasites, it causes muscle blockade in them. Thanks to this, they are easily removed without requiring additional stimulation. Moreover, individuals do not migrate because they are immobilized.

Effective for helminths at any stage of development, except for larvae that migrate in tissues.

It is important to remember that Pirantel should not be taken by people who have an individual intolerance to any substances in its composition or by patients with liver failure.

Symptoms of helminth damage

The first symptom indicating the need for examination should be any allergic reaction without obvious contact with a possible allergen. An example would be a rash that was not preceded by contact with aggressive substances or abuse of foods from a group of potential allergens. Also, long-term bronchitis, treatment of which by a therapist does not give a positive result, may indicate the presence of a parasite.

Abnormal bowel movements are another reason to get tested for helminthiasis. If the parasite has settled in the intestines, it can interfere with normal peristalsis and bowel movements. When the intestines become a haven for certain dangerous types of worms, a person may experience a lack of strength and may also develop anemia or severe lack of nutrients in the blood. This is explained by the fact that the parasite eats all the beneficial substances in the intestines faster than they can be absorbed into the blood. Therefore, weakness is also a symptom.

Pinworms infect the anus. As a result, itching in the anus is the main symptom of the presence of the parasite. The female pinworm emerges mainly at night through the anus and lays eggs in the folds of the anus, lubricating them with her secretion. The substance irritates the mucous membrane, causing itching.

Oddly enough, nighttime teeth grinding has nothing to do with helminth infection. This is an erroneous opinion based on the assumptions of older generations. A person begins to grind their teeth due to the characteristics of the nervous system.

If there are parasites in the body, the number of eosinophils in the blood increases. The number of these cells also increases with a progressive allergic reaction. Therefore, if the number of eosinophils in the biochemical blood test is higher than normal, you should be tested for helminthiasis.

Pyrantel tablets: rules of administration

In order to quickly and easily expel parasites from the body, you need to chew one tablet of the drug with water.

The timing of meals is not important; there is also no need to take any laxatives as auxiliary medications.

If you are diagnosed with enterobiasis or enterobiasis + ascariasis, you will most likely be prescribed a dose of 10 mg per kilogram of body weight.

You can follow this regimen:

1. Child from three to six years old - 250 mg;
2. Child from six to twelve years old - 500 mg;
3. Children over twelve years of age or adults weighing less than 75 kg - 750 mg;
4. Adults of any weight - 1000 mg;

Release forms

You can buy Pirantel in several forms:

• Suspension. It is prescribed to children because this form makes it easier to take.
• Pills. They are preferred by adult patients who do not have problems swallowing solid food.

5 ml of suspension contains 250 mg of active ingredient. The volume of one bottle is 15 ml. Tablets are packaged in quantities of 3 pcs. packaged. One tablet is equivalent to 250 mg of the substance. The small number of doses in one package is explained by the high effectiveness of the drug. For the treatment of most types of lesions, a single dose of a calculated dose is sufficient, the volume of which depends on the body weight and age of the patient.

The nuances of using Pirantel:

• For severe infection, a double dose is needed - 20 mg per kilogram of body weight once or twice a day. The duration of treatment is two to three days.
• Isolated ascariasis is treated with a regimen of 5 mg per kilogram of body weight once a day.
• Hookworm disease, necatoriasis, ascariasis + necatoriasis or any combination of helminth infestations can be eliminated by drinking Pirantel 10 or 20 mg per kilogram of body weight, depending on the severity of the disease, the patient’s age and weight.

It is better for adults to take the drug in tablet form. When treating a child under three years of age for helminths, it is better to give him a suspension.

Characteristics of giardiasis

Giardiasis belongs to the group of intestinal infections, and develops when Giardia enters the lumen of the small intestine. This disease is widespread, and in developed countries the incidence of giardiasis ranges from 3 to 5%. In developing countries, the prevalence of giardiasis ranges from 10 to 15%. Children attending preschool and school institutions are at increased risk of contracting this protozoal infection.

Reasons for development

By their nature, Giardia are the simplest single-celled parasites. These microorganisms feed by osmosis. The source of the spread of infection is a sick person who releases Giardia in feces into the environment. Giardiasis can also be spread by animals (guinea pigs, cats, rabbits, dogs). Favorable conditions for the spread of infection and infection of people are created in areas with low quality drinking water, insufficient personal hygiene skills among the population, as well as large overcrowding of people.

Predisposing factors for the development of giardiasis include:

1. physical exhaustion;
2. children under 10 years of age;
3. chronic cholecystitis and biliary dyskinesia;
4. congenital or acquired defects of the biliary tract
5. previous gastric surgery
6. protein deficiency in the diet.

Once in the lumen of the digestive tract, the causative agents of giardiasis migrate towards the duodenum, after which they are transformed into vegetative forms. Next, Giardia reaches the proximal jejunum and attaches to the epithelial villi. This process is accompanied by mechanical damage to intestinal epithelial cells (enterocytes) and disruption of the absorption process.

Clinical symptoms

From the moment the causative agents of giardiasis penetrate the internal environment of the body until the appearance of clinical symptoms, 1 to 3 weeks pass. The main symptoms of giardiasis in adults include:

1. decreased appetite, feeling of heaviness in the stomach;
2. nausea and vomiting;
3. alternating constipation and diarrhea;
4. watery or foamy stools interspersed with fat;
5. pain in the right hypochondrium;
6. increased gas formation in the intestines (flatulence);
7. weight loss, asthenia.

The acute phase of clinical symptoms of damage to the small intestine can last from 5 to 7 days. After completion of the acute phase, giardiasis spontaneously resolves or becomes chronic subacute.

The severity of intoxication directly depends on the scale of invasive intestinal damage by Giardia. In addition to the listed symptoms, giardiasis may be accompanied by an increase in body temperature to subfebrile levels, enlargement of regional lymph nodes, fatigue, bruxism and emotional lability. If this disease develops in childhood, it is often accompanied by hyperkinesis, decreased blood pressure and fainting.

Pyrantel suspension: application features

Alternative release form. Shake the bottle before use. Take the medicine internally.

If you have enterobiasis or ascariasis, calculate the dosage at 10–12 mg per kilogram of body weight. On average, it looks like this:

• children from six months - 2.5 ml of substance per 10 kg;
• adults weighing less than 75 kg - 15 ml per dose;
• adults weighing more than 75 kg - 20 ml per dose.

Hookworm infection in severe form or in an endemic area is treated according to the following scheme:

• children from six months - 5 ml per 10 kg;
• adults weighing less than 75 kg - 30 ml per dose;
• adults weighing more than 75 kg - 40 ml per dose.

If the area is not endemic or the invasion is mild, then a double dose is not needed. It is enough to drink Pyrantel syrup at a dosage of 10 mg/kg once a day.

Pyrantel for worms: side effects and overdose

Clinical studies have proven that patients tolerate the medicine well. In rare cases, the following side effects may occur:

• epigastric discomfort, gagging, frustration, nausea, spasms;
• liver transaminases are active;
• dizziness or headache, lack of sleep, increased fatigue;
• the skin itches, hives or other rash appears.

With an overdose of the substance, adverse reactions intensify. It is necessary to rinse the stomach, monitor the condition of the body, and carry out symptomatic therapy.

Adverse reactions

Pyrantel rarely causes unpleasant symptoms in patients. But in rare cases, the following may occur:

• headache;
• drowsiness;
• sleep disorders;
• confusion;
• nausea;
• stool disorder;
• stomach pain;
• rash on the body;
• temperature increase.

The risk of adverse reactions directly depends on the single dose taken. If any symptom appears, you should consult a doctor to change the course of therapy, as well as to clarify the single daily dose. Intestinal disorders often occur when the calculation is incorrect, resulting in an overdose of the substance.

Special instructions and contraindications

For pregnant women and those who are breastfeeding, Pirantel is not dangerous. In this case, it is not recommended to drink it yourself. You should follow the instructions and dosage prescribed by your doctor. The doctor prescribes such a drug, weighing the risks to the fetus.

For children, the drug Pirantel is as effective as for adults, but it is better to take it in the form of a suspension.

For those who drive a car or any other vehicle, the tablets are safe. If you feel unwell or have adverse reactions, stop driving.

Popular questions about Pirantel

Pyrantel - how to take the drug?

The drug in the form of a suspension or tablets is taken orally at a dose of 10 mg per 1 kg of body weight.

Pirantel - how do worms get out?

Under the influence of sodium in the medicine, helminths receive muscle blockade, lose the ability to move and are excreted in the feces.

How to take Pirantel for prevention?

Adults and children can take 1 tablet at a time at the rate of 10 mg of substance per 1 kg of weight.

Note!

The description of the drug Pirantel on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Diagnostic methods

The clinical symptoms of giardiasis are nonspecific, so it is impossible to diagnose this pathology based on complaints. To diagnose giardiasis, the following examination methods are prescribed:

1. cholecystography;
2. ultrasound examination of the abdominal organs;
3. general blood analysis;
4. biochemical blood test;
5. parasitological examination of feces;
6. stool analysis for dysbacteriosis;
7. laboratory examination of duodenal contents.