An effective natural uroantiseptic that is absolutely safe for the body is the product. Kanaferon. Its composition consists exclusively of plant components:
- Centaury herb, which has anti-inflammatory and antimicrobial effects.
- Lovage root, which has diuretic, antispasmodic, analgesic, anti-inflammatory, antibacterial properties.
- Rosemary leaves, which help activate the immune system and reduce the proliferation of pathogenic microorganisms
The drug Canephron N, the instructions indicate this, is available in two forms, which are available without a prescription. This:
- Kanaferon tablets are orange tablets with a biconvex round shape.
- Canephron drops are transparent with a slight yellowish-brown color.
Compound
The composition of Canephron N, produced in the form of dragees, includes 18 mg of dried centaury herb , rosemary leaves and medicinal lovage roots (in powder form), as well as corn starch (Maydis amylum), colloidal silicon dioxide (Silicium dioxide colloidal), lactose monohydrate ( Lactose monohydrate), povidone, modified corn starch (Modified maydis amylum), riboflafin (E101; Riboflavin), calcium carbonate (Calcium carbonate), dextrose (Dextrose), titanium dioxide (Titanium dioxide), talc (Talc), sucrose (Saccharose), shellac (Shellac), corn oil (Oleum maydis), red iron oxide (E172), glycol rock wax.
The composition of 100 grams of Canephron N drops includes 29 grams of aqueous-alcoholic extract prepared using the herb Centaury , rosemary leaves and medicinal lovage roots (to prepare 100 ml of extract, 600 mg of medicinal raw materials from each plant component is used) and excipients: 16- 19.5 vol.% ethanol (Ethanol) and purified water (Aqua purificata).
Release form
The annotation for the drug indicates that Canephron N is available in the form of dragees and in the form of a solution for use per os (orally).
- The dragees are biconvex and have a round shape. Their surface is smooth and their color is orange. The dragees are sold packaged in 20 pieces in blister packs, 3 packs in a cardboard box.
- The solution is a clear and slightly cloudy aromatic liquid of a yellowish-brown color. In pharmacies it is sold in 100 ml bottles equipped with a dosing drip device.
During storage, the solution may become slightly cloudy and a small amount of sediment may form at the bottom of the bottle. Neither one nor the other affects the pharmacological activity of the drug.
Pharmacodynamics and pharmacokinetics
The drug is characterized by anti-inflammatory and antispasmodic activity and is intended for the treatment of urological diseases .
Thanks to a unique combination of medicinal herbs, which are the active substances of Canephron N, the drug has a diuretic effect , reduces the intensity of inflammation, eliminates urinary tract spasm antibiotic treatment , normalizes the process of urination, and reduces the risk of developing repeated exacerbations of chronic cystitis .
Used as one of the components of complex treatment of cystitis , Canephron N helps reduce the severity of pain in the bladder and the disappearance of pain when urinating.
The drug is well tolerated and can be used in combination with antibacterial agents , even if long-term use is necessary.
Canephron N is also effective for the treatment of patients who suffer from chronic inflammatory diseases and require ongoing maintenance or anti-relapse therapy.
Numerous studies confirm that the use of the drug reduces the number of repeated exacerbations of chronic inflammatory diseases of the urinary tract , as a result of which their functional state significantly improves.
The chemical composition of the medicinal plants included in Canephron N is represented by essential oils, phenolcarboxylic acids and a number of other biologically active substances that have a pronounced antiseptic effect . A similar effect is observed when using dragees and Kanefon N solution.
The herbal components of the drug affect the system of glomeruli and tubules of the kidneys , which reduces protein excretion in patients with proteinuria .
Pharmacokinetic characteristics of the drug are not provided.
Indications
Canephron is prescribed as an independent medicine or as one of the components of complex treatment:
- for acute diseases of the kidneys and urinary tract, and also for the chronic course of the disease and as a preventive therapy;
- as an auxiliary component in the treatment of urolithiasis, as well as after stone removal.
- For cystitis, Canephron is taken as an antibacterial agent. During the process of disease in the human genitourinary system, bacteria actively and quickly multiply and enter the bladder through the urethra. This is what provokes acute pain attacks and frequent urge to urinate. Canephron helps destroy bacteria.
- In the treatment of pyelonephritis, the drug plays an auxiliary role and is prescribed in combination with other drugs.
- When diagnosing a sexually transmitted infection, urethritis, antibacterial treatment is also necessary. Canephron is prescribed in combination with antibiotics. Thanks to this combination, the effect of additional disinfection is achieved, and the increased diuretic effect allows you to quickly cope with the infection. In addition, the herbal components that make up Canephron have a calming effect, reducing pain.
- In the treatment of urolithiasis, Canferon is also used in combination with other drugs. During the course of the disease, the patient experiences severe acute pain, which is provoked by sand and kidney stones. Canephron helps relieve renal colic and promotes faster removal of sand from the patient’s body.
- The drug is prescribed as an antibacterial agent for prostatitis.
In addition, Canephron is used as a prophylactic agent, as well as in the treatment of inflammation of the external genitalia, disorders of the gastrointestinal tract and other infectious diseases accompanied by acute pain.
Indications for use
What does the medicine help with? In the description of the drug, the manufacturer indicates that this product can be used both for the main (basic) treatment and as a component of complex therapy, the purpose of which is to treat acute and chronic forms of infectious diseases of the bladder and kidneys (including cystitis and pyelonephritis ).
Indications for the use of Canephron N are also chronic kidney diseases of non-infectious origin , including interstitial nephritis and glomerulonephritis .
As a prophylactic agent, Canephron N is prescribed to prevent the development of urolithiasis (the use of the drug is also indicated for patients who have undergone surgery to remove urinary stones).
Taking pills
Adult patients are prescribed 2 tablets three times a day. Children over 6 years old are prescribed 1 tablet also three times a day.
It is not necessary to chew the tablets. They are covered with a smooth shell, which makes them easy to swallow. After the acute period of the disease has passed, treatment is continued for another two to four weeks.
The drug is continued after the acute period of the disease has passed. It usually takes two to four weeks. The exact date is determined by the doctor.
Canephron treatment regimens
The standard period during which Canephron is taken is 21 days. It is during this period of time that the remedy not only manages to destroy pathogenic bacteria, but also prevents their reappearance and a new outbreak of exacerbation.
The exact course of treatment is prescribed by the doctor depending on the established diagnosis and indications. Before taking Canephron, you must undergo all tests and collect anamnesis. For example, when treating cystitis and pyelonephritis, a longer course may be required. In addition, complex treatment is often required in conjunction with other drugs, including the use of antibiotics.
Contraindications
The use of the drug Canephron N in the form of a solution is contraindicated in case of alcohol dependence, as well as in patients with hypersensitivity to the components of the drug. Also, the solution should not be prescribed to persons who have successfully completed treatment for chronic alcoholism.
It is recommended to use the drug in this dosage form with caution if the patient is diagnosed with certain liver diseases (Canephron N can be prescribed only after consultation with a doctor and assessment of the feasibility of use).
Contraindications to the administration of tablets are hypersensitivity to their constituent components, as well as age under 6 years.
In addition, both dosage forms are contraindicated:
- patients with peptic ulcers in the acute stage of the disease;
- to relieve edema in patients with renal or heart failure .
Canephron N is not advisable to use as the main agent for the treatment of patients with insufficiency of renal function .
Contraindications and side effects
Despite its herbal composition, the drug Canephron has contraindications. Tablets are allowed to be prescribed to children over 6 years of age. Since the medicine has a choleretic effect, it should not be taken for gastric ulcers in the acute stage. Contraindication is individual intolerance to the components of the drug.
Other warnings:
- Canephron solution is made on the basis of 20% ethanol. Therefore, caution must be exercised when prescribing it for the treatment of patients suffering from alcoholism.
- Only after preliminary consultation with a doctor is it permissible to treat with the drug during pregnancy and lactation. In this case, the dosage and course of treatment are selected individually.
Caution should be exercised when taking the drug in the presence of many other pathologies. All of them are indicated in the instructions for use. You need to take into account certain properties of plant components:
- Lovage can cause bleeding, which is dangerous during pregnancy, as the drug can cause a miscarriage.
- Centaury increases blood clotting. It poses certain threats to peptic ulcers.
- Rosemary can increase blood pressure and cause insomnia, as well as cause dyspepsia.
If you follow the rules for taking the drug and all the doctor’s recommendations, then adverse reactions of the body are rarely observed. The main ones are dyspeptic disorders. There may also be discomfort in the urethral area.
Side effects
Clinical studies have shown that Canephron N is well tolerated by patients.
In patients with hypersensitivity, side effects were expressed mainly in the form of hyperemia and itching of the skin , the appearance of rashes on it, and urticaria .
In some cases, side effects such as vomiting, nausea, and a laxative effect occurred.
If certain adverse reactions develop in connection with taking Canephron N, treatment with the drug should be stopped and consult a doctor. hematuria (the appearance of blood in the urine), acute urinary retention, and urinary disorders require urgent medical attention
Instructions for use of Canephron N
Both dosage forms of the drug can be recommended for long-term use. The timing of treatment depends on what the tablets or drops are prescribed for, as well as on the severity of the pathological process.
After the clinical effect is achieved, it is considered optimal to take Canephron N for another 14-18 days. According to indications, treatment courses are allowed.
Canephron N is available only in the form of an oral solution and in the form of dragees, so there is no point in looking for other dosage forms (for example, suppositories or an injection solution).
Canephron N: how to take - before or after meals?
The instructions that the manufacturer encloses with the drug do not contain clear instructions as to what time is best to take the pills and solution, as well as any information regarding the effect of food intake on the pharmacokinetic characteristics of the drug.
In this regard, the patient makes the decision when to take Canephron - before or after meals - at his own discretion.
Canephron tablets: instructions for use
The optimal dosage of the drug in the form of pills is selected individually depending on the age of the patient.
Adult patients are advised to take 2 tablets, schoolchildren - 1 tablet. The frequency of doses is 3 times a day.
The dragee should be swallowed whole with a small amount of liquid.
Canephron drops: instructions for use
Drops should be dosed depending on age. A single dose for an adult is 50 drops, for schoolchildren - 25 drops, for a preschool child - 15 drops, for an infant - 10 drops.
The frequency of doses is 3 times a day.
Before use, the drug must be diluted in a small amount of liquid. Since the solution has a bitter taste, small children are allowed to mix it with any liquids.
Instructions for use during pregnancy
Before taking Canephron N during pregnancy, it is imperative to consult with the doctor managing the pregnancy, and also carefully study the instructions included with the drug.
The frequency of administration and dose are determined by the attending physician depending on the degree of development and characteristics of the pathological process.
As a rule, the standard regimen for using Canephron N during pregnancy involves taking 6 tablets or 150 drops of solution daily. The indicated dose should be divided into 3 doses.
Depending on the doctor's decision, other options for taking the medicine are possible: for example, 30 drops three times a day or 20 drops twice a day. The dosage may also be lower in cases where the drug is prescribed for prophylactic purposes.
The duration of Canephron administration depends on the clinical situation.
Application in veterinary medicine
Canephron N is often prescribed as a cure for cystitis in cats. The standard dose is 1 tablet per day. It should be divided into 2 doses.
Taking the solution
The drug does not have a very pleasant taste, so it is recommended to either dilute the dose in water or simply drink it with a large amount of warm liquid.
Inside, diluted in a small amount of water or washed down with water. Adults: 50 drops 3 times a day. School-age children: 25 drops 3 times a day. For preschool children (over 1 year): 15 drops 3 times a day. After the severity of the disease has subsided, treatment with the drug should be continued for 2-4 weeks.
If necessary, for example, to soften the bitter taste for children, the drug can be taken with other liquids. During treatment with the drug, it is recommended to consume plenty of fluids. Shake before use!
Best before date
Shelf life for tablets is 4 years, for solution - 2 years from the date of issue. The contents of an opened bottle are suitable for use for six months. The expiration date indicated on the package of tablets determines the possibility of using them before the last day of the month.
During storage of the solution, sediment may form, which is due to the herbal components included in the preparation. This effect does not affect the safety and pharmacological properties of Canephron N.
Medicine Canephron
Thanks to the properties of the herbal components that make up the drug, Canephron in terms of effectiveness and safety is in many ways superior to analogues from the same series of drugs for problems with the health of the kidneys and genitourinary system. The active components of the drug stop inflammatory processes and have an antimicrobial effect at the same time.
Composition of Canephron
The composition of the drug is dominated by herbal components, which are supplemented and enhanced by excipients:
- centaury grass,
- lovage root
- common rosemary leaves,
Lactose monohydrate, corn starch, silicon dioxide, magnesium stearate, povidone K 25 are used as additional ingredients that enhance the effect of plant components.
Release form and dosage
The drug is produced in two versions - solution and tablets.
special instructions
During treatment with Canephron it is necessary to drink as much fluid as possible.
When using the drug in the form of an oral solution, the bottle should be stored in an upright position. Before using the drops, the bottle with the solution must be shaken.
When using the tablet form to treat patients with diabetes , it should be remembered that 1 tablet contains less than 0.04 XE (bread units) of digestible carbohydrates.
The solution contains 16-19.5% ethyl alcohol (volume).
When used in therapeutic doses, the medicine does not affect the speed of psychomotor reactions and does not impair the ability to drive a car or any other mechanisms.
What is better - drops or tablets?
It is believed that there is no fundamental difference between Canephron drops and tablets for the kidneys . However, some doctors are inclined to argue that this opinion is not entirely accurate, and drops have a number of advantages over the tablet form.
Firstly, the contents of one bottle are enough for a full course of treatment lasting a month. A package of pills No. 60 at the same cost is enough for 10 days, and therefore the course of treatment will cost 2-3 times more.
Secondly, dragees are contraindicated for people with intolerance to the sugars they contain (glucose, lactose, sucrose, galactose). The solution contains only herbs and alcohol, so it can also be used to treat this category of patients.
Thirdly, the likelihood of allergic reactions to the tablet form of Canephron is an order of magnitude higher than to the solution. This is due to the fact that the dragee contains a larger number of components, including dyes, which often provoke allergies .
Fourthly, drops can be used from the age of one, while tablets are prescribed only from 6 years of age.
Analogues of Canephron N
Level 4 ATX code matches:
Renel
Samprost
Lingonberry leaves
Uriflorin
Gentos
Bioprost
Bearberry leaves
Testis compositum
Birch buds
Lespefril
Prostopin
Lespeflan
Phytonephrol
Lespenefril
Vitaprost Forte
Vitaprost Plus
Vitaprost
Brusniver
Speman Forte
Speman
Analogs and substitutes for Canephron N are the drugs Afala , Bioprost , Vitaprost , Ichthyol , Lespeflan , Lespefril , Prostanorm , Prostatilen , Renel , Rovatinex , Samprost , Solidago compositum S , Speman , Superlymph , Tentex Forte , Testis compositum , Uroprost , Urotravenol , zine , Flaronin , Khimkolin , Cyston , Priligy , Urological collection .
Domestic analogues are Vitaprost and Vitaprost Plus (Nizhpharm), Lespefril (ZAO Vifitech), Bioprost (IntelPharm).
Analogues in Ukraine - Apiprost , Trinephron (Zdorovye LLC); Nephrofit (Eim LLC), Uronephron (Farmak OJSC), Fitourolite (KP Lugansk FF).
The price of Canephron N analogues varies from 10 to 560 UAH. As a rule, domestically produced substitutes are more affordable than imported analogues. For example, Nephrofit , produced by the Ukrainian company Aim, will cost the buyer approximately 17-20 UAH, but the average price of the German drug Solidago Compositum C (Heel) is 370 UAH.
What can replace Canephron N during pregnancy?
Pregnant women, along with Canephron N, are prescribed the drugs Monurel , Phytolysin , Cyston .
Which is better: Canephron or Cyston?
Both Canephron and Cyston are drugs with a natural composition. They have a minimum number of contraindications and provoke a minimum of side effects.
The main advantages of Canephron over Cyston are:
- lower likelihood of developing allergic reactions (this is due to the fact that Canephron contains a smaller amount of herbal components);
- the ability to reduce the amount of protein excreted in the urine (this feature of the drug can be very useful during pregnancy);
- the presence of a dosage form that is convenient to use for the treatment of young children.
The advantages of Cyston are:
- more affordable price;
- more pronounced antibacterial effect (this is due to the richer composition of the drug);
- high efficiency in removing oxalate and phosphate urinary calculi .
Unlike Canephron, Cyston is characterized by the ability to relieve attacks of renal colic and is effective in conditions that are accompanied by an increase in the concentration of uric acid in the blood . In addition, it can be used to treat gout and urinary incontinence in women.
allergic reactions an order of magnitude more often than Canephron , which is due to its richer composition.
Although the spectrum of use of both drugs is similar, they will have different effects on different patients.
So, for example, when choosing a means for removing stones from the kidneys, it should be taken into account that for people who have kidney stones formed by uric acid salts, Canephron will be more effective, and if necessary, it is more advisable to prescribe stones formed by deposits of inorganic calcium compounds. Cyston.
In the treatment of infectious diseases of the urinary system, both drugs show approximately the same effectiveness. In this situation, the fundamental selection criterion for some patients is the price of the drug.
Herbal preparation CANEPHRON in urological practice
Treatment of kidney and urinary tract diseases with medicinal plants has a long history. However, there was a period when doctors used them little. In recent years, the “well forgotten old” has regained its position.
Medicinal plants are increasingly used as therapeutic agents prescribed by internists, nephrologists and urologists.
Their advantages over synthetic drugs are obvious in most cases. Firstly, there are no complications or unwanted side effects. Secondly, there is a wide scope for maneuvering, which is provided by a rich selection of plants with different types of action. It would be irresponsible to claim that medicinal plants can cure any disease, that is, they are a panacea.
The priority of their use is dictated by the nature of pathological changes, the phase of the disease, and the presence of complications.
One of the rules of herbal medicine can be formulated as the principle of its indication and priority. Guided by this principle, the role of medicinal plants at a certain stage of the disease should be determined. It can be basic, parity and auxiliary. The second principle of herbal medicine is the principle of its individuality.
We want to share our observations about the herbal preparation canephron (Bionorica, Germany), which appeared in our country not so long ago, but has been produced in Germany since 1934. This period of use of the drug in itself already indicates its effectiveness. Canephron is a combination drug of plant origin. It contains centaury (Herba Centaurii), lovage (Radix Levistici), rosemary (Folia Rosmarini), rose hips (Fructus Cynosbati).
The substances included in the drug have an antiseptic, antispasmodic, anti-inflammatory effect on the genitourinary tract, reduce the permeability of the capillaries of the kidneys, have a diuretic effect, improve kidney function, and potentiate the effect of antibacterial therapy (see table).
| Medicinal plants and their spectrum of action | |||
| Medicinal origin | centaury | Lovage | Rosemary |
| Bitters, phenolcarbolic acids | Essential oils, phthalides | Rosmarinic acid, essential oils, flavonoids | |
| Diuretic | + | + | + |
| Antispasmodic | — | + | + |
| Anti-inflammatory | — | — | + |
| Antibacterial | + | + | + |
Centaury herb contains alkaloids, flavonoid compounds, bitter glycosides, and phenolic acids.
Rosehip peel contains a large amount of ascorbic acid, organic acids, a lot of sugar, pectic acids, organic acids (citric and malic), as well as carotene.
Lovage contains essential oils, phenolcarboxylic acids, and phthalides.
Rosemary contains rosmarinic acid, essential oils and flavonoids.
Various types of effects of canephron on the body are due to its constituent essential oils (lovage, rosemary), phenolcarboxylic acids (rosemary, lovage, centaury), phthalides (lovage), bitters (centaury).
The diuretic effect of canephron is due to the combination of various points of application of medicinal substances. Essential oils dilate the blood vessels of the kidneys, which improves blood supply to the renal epithelium, and also influence the function of the epithelium of the renal tubules. This manifests itself mainly in a decrease in the reabsorption of Na+ ions and the corresponding amount of water. The diuretic effect of phenylcarboxylic acids is explained by the osmotic effect. The principle of action is that when they enter the lumen of the renal tubules, they create high osmotic pressure (these drugs are not subject to reverse absorption), and the reabsorption of water and Na+ ions is significantly reduced.
Due to the removal of excess fluid and sodium salts from the body, canephron helps lower blood pressure. Herbal diuretics act somewhat weaker and slower than modern synthetic drugs, but they are more gentle.
As is known, the main signs of inflammation are associated with the action of inflammatory mediators (bradykinin, prostaglandins, histamine, serotonin, etc.). The anti-inflammatory properties of canephron are mainly provided by rosmarinic acid and are associated with suppressing the synthesis of inflammatory mediators or slowing down their release and activation.
All medicinal plants that make up canephron contain substances (phenolcarbolic acids, essential oils, etc.) that have an antimicrobial effect. It is important to emphasize the wide antimicrobial spectrum of medicinal plants and their activity against microflora resistant to synthetic drugs. The advantage of these medicinal plants is the combination of antimicrobial and anti-inflammatory properties, which is especially valuable for chronic processes in the urinary tract. It has been established that canephron enhances the excretion of uric acid salts. This side of the action is only partly related to the diuretic effect and is quite specific. Increasing the secretion of uric acid prevents the loss of crystals in the urinary tract, the growth of existing stones and the formation of new ones. It was also noted that this drug alkalinizes the urine, if it is sharply acidic in urate nephrolithiasis, and keeps it within 6.2–6.8, which also prevents the formation of urate stones.
The antispasmodic effect of canephron is due to flavonoids.
The pharmacologically proven effect of canephron on the tubular apparatus of the kidney clearly shows that the excretion of protein in the urine due to previously suffered pathological processes damaging the tubular apparatus is significantly reduced.
We used Canephron in the urological clinic of the I.M. Sechenov Moscow Medical Academy in various groups of patients.
Treatment with this drug was carried out in 68 patients: 18 patients suffering from chronic pyelonephritis, 15 patients with chronic cystitis, 17 patients with nephrolithiasis. In 18 patients, Canephron was used after shock wave lithotripsy.
During treatment, in 16 patients with chronic pyelonephritis, leukocyturia disappeared after a three-week course. In 15 patients with chronic cystitis, dysuria disappeared on the 10th day after treatment; on the 19th day, urine analysis returned to normal.
We also found that in patients suffering from urate nephrolithiasis, and there were 17 of them, on the 5th day the pH of urine became within the range of 6.2–6.8, and this is one of the main conditions in the treatment of urate stones and the prevention of their formation . It was also noted that the daily excretion of uric acid increased in all of these patients.
Thus, these results indicate that Canephron should be more widely used in patients suffering from urate nephrothiasis for prevention and treatment.
Thanks to the antispasmodic and diuretic effect of canephron, in patients of all groups with various diseases, daily diuresis increased to 2.2–2.5 l, while there was no change in the Na+ concentration in the biochemical blood test.
This suggests that this drug is a mild herbal diuretic.
It is known that the sooner the stones pass after shock wave lithotripsy, the better. The use of Canephron in this group of patients showed that in all patients taking the drug, the fragments passed within 4-5 days. In the control group, stones passed within 5-14 days.
Thus, the herbal preparation canephron has a wide spectrum of action, although in our study we examined only its antimicrobial, anti-inflammatory, antispasmodic and diuretic activity.
However, judging by the available data, canephron is widely used for renal failure, proteinuria, and interstitial nephritis. Canephron is indicated for a large group of patients suffering from chronic inflammatory diseases: pyelonephritis, cystitis. It should be prescribed to patients with urate nephrolithiasis, as well as for the passage of small stones after shock wave lithotripsy.
No side effects or complications were observed when using this drug for 4, 6, 8 weeks.
The drug can be recommended for both children and adults; it is also prescribed to pregnant women suffering from inflammatory diseases of the urinary system.
For children
For children over one year of age, Canephron is prescribed in the form of drops. The tablets are indicated for use from the age of six.
However, the drug is often prescribed to children under one year of age. The optimal dosage for infants is 30 drops per day, divided into 3 doses.
The medicinal plants that are part of the solution are well tolerated by children, and the concentration of alcohol in it is not so high as to harm the child’s body. Therefore, it is believed that Canephron is absolutely safe for infants under one year of age.
In this case, the drug can be used for a long time and in combination with any other medications.
The only side effects may be allergic reactions caused by individual intolerance to one or another component.
Canephron during pregnancy
Is it possible to take Canephron during pregnancy? The answer to this question is yes.
Since the drug contains a complex of medicinal plants, expectant mothers are often prescribed Canephron for cystitis , pyelonephritis and glomerulonephritis, as well as for a number of other problems with the urinary system .
Many women are also interested in whether Canephron is a diuretic or not, and whether pregnant women can take it for edema.
As the manufacturer indicates, the drug has a pronounced antimicrobial and antibacterial effect , relieves spasms, prevents the development of infections in the urinary tract , improves the functional state of the kidneys and bladder , which experience increased stress during pregnancy and often need support.
In addition, drops and tablets have a diuretic effect, which allows them to be used as a remedy for swelling that can accompany pregnancy. The drug helps reduce swelling, reduces the intensity of lower back pain and improves the overall health of women.
In some cases, the doctor may advise taking Canephron N to prevent gestosis and exacerbation of various types of renal pathologies , which are extremely undesirable during the period of bearing a child.
So, why is Canephron prescribed during pregnancy:
- for the treatment of infectious and non-infectious diseases of the urinary tract (the drug is effective for cystitis , interstitial nephritis , pyelonephritis , glomerulonephritis );
- for the prevention of nephrolithiasis (kidney stones);
- to reduce protein excretion in urine.
One of the advantages of the medicine is that it can be safely taken for a long time, if necessary (including during breastfeeding).
In addition, the use of Canephron during lactation does not oblige a nursing mother to switch her baby to formula and cereals, but allows her to continue breastfeeding without fear of harming the baby’s health.
The standard dosage of Canephron during pregnancy is as follows - 6 tablets or 150 drops with a frequency of applications 3 times a day. However, sometimes during pregnancy the tablets are prescribed to be taken 1 twice a day, and the solution - 25-50 drops twice a day.
Despite the fact that the drug has virtually no contraindications and rarely causes unwanted side effects, it should be remembered that its main components - rosemary and lovage - have the ability to increase the tone of the uterine muscles.
In their pure form, these plants are contraindicated for pregnant women, therefore, when treating with Canephron, you should strictly adhere to the regimen prescribed by your doctor.
Reviews of Canephron N
Reviews about Canephron N left on the forums are overwhelmingly good. For many patients, the drug is a kind of lifesaver.
Its main advantages are its natural composition (and the solution also contains a minimum of auxiliary components), the absence of side effects, the ability to take tablets and drops for a long time, including during pregnancy and breastfeeding.
Reviews of Canephron during pregnancy indicate that the drug acts quickly, gently and effectively. The product quickly eliminates unpleasant symptoms, removes excess fluid from the body, normalizes the concentration of protein in the urine and improves the general condition of the kidneys and urinary tract .
For renal colic, it significantly reduces the intensity of pain, accelerates the passage of stones and prevents the development of cystitis .
Many positive reviews were also left by mothers who used Canephron N for children. Drops are prescribed to children in accordance with the instructions from the age of one year, however, in situations where this is necessary, they can also be used to treat infants.
Based on the reviews of doctors, we can conclude that the effectiveness of the drug directly depends on how correctly the treatment regimen is selected. For example, for cystitis or pyelonephritis, it is advisable to prescribe Canephron N in combination with uroseptics , antibiotics or bacteriophages .
Canephron N tablets p/o No. 20x3
Name
Canephron H tablet p/o in bl. in pack №20x3
Manufacturer
Bionorica Germany
Manufacturer country
Germany
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children.
Expiration date from date of manufacture
3 years
Product description
Orange, round, biconvex, film-coated tablets with a smooth surface.
pharmachologic effect
Diuretic of plant origin. The drug has a diuretic, antispasmodic, anti-inflammatory, and antimicrobial effect.
Indications for use
The drug is used in complex therapy in the treatment of chronic infections of the bladder (cystitis) and kidneys (pyelonephritis), for non-infectious chronic inflammation of the kidneys (glomerulonephritis, interstitial nephritis), as a means of preventing the formation of urinary stones (also after removal of urinary stones).
Use during pregnancy and lactation
The use of the drug during pregnancy and breastfeeding is possible only as prescribed by a doctor, in strict accordance with the recommendations for use and after the attending physician has assessed the risk-benefit ratio.
special instructions
For edema caused by cardiac or renal dysfunction, consuming large amounts of fluid is contraindicated. In case of impaired renal function, the drug should not be prescribed as monotherapy. In case of inflammatory kidney disease, you should consult a doctor for advice. If there is blood in the urine, pain when urinating, or acute urinary retention, you should immediately consult a doctor. The digestible carbohydrates contained in one tablet are less than 0.04 “bread units” (XU). Effect on the ability to drive vehicles and machinery The drug does not affect the ability to perform potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (including driving vehicles, working with moving mechanisms).
Contraindications
Hypersensitivity to the components of the drug. Children's age (up to 6 years). Peptic ulcer of the stomach and duodenum in the acute stage. Lactase deficiency, lactose intolerance, glucose-galactose malabsorption. Sucrase/isomaltase deficiency, fructose intolerance.
Directions for use and doses
Orally, without chewing, with water. Adults: 2 tablets 3 times a day. School-age children: 1 tablet 3 times a day. After the severity of the disease has subsided, treatment with the drug should be continued for 2 to 4 weeks. During treatment with the drug, it is recommended to consume plenty of fluids.
Overdose
At the moment, there is no data on overdose and intoxication. In case of overdose of the drug, symptomatic treatment is prescribed. Side effects: Allergic reactions are possible. Gastrointestinal disorders (nausea, vomiting, diarrhea) are possible. If signs of an allergic reaction appear, you should stop taking the drug.
Compound
In 1 tablet: Active ingredients: crushed medicinal plant materials: Centaury herb 18 mg Lovage medicinal root 18 mg Rosemary leaves 18 mg Excipients: lactose monohydrate, magnesium stearate, corn starch, povidone K 25, colloidal anhydrous silicon dioxide. Shell: calcium carbonate, castor oil, glucose, red iron oxide dye (E 172), corn starch, dextrin, mountain glycol wax, povidone K 30, riboflavin, shellac, sucrose, talc, titanium dioxide
Interaction with other drugs
Combination with antibacterial agents is possible and advisable. Interactions with other drugs are currently unknown.
Release form
Film-coated tablets. 20 film-coated tablets are placed in a blister made of aluminum foil and polyvinyl chloride/polyvinylidene chloride film. 3 or 6 blisters along with instructions for use are placed in a cardboard pack.
Dispensing the drug
Over the counter
Manufacturer's country of origin
Germany
Basic shelf life (in months)
36
Method of drug administration
Oral
Nosological classification ICD-10 (name)
Chronic nephritic syndrome (chronic glomerulonephritis); Chronic tubulointerstitial nephritis; Kidney and ureteral stones; Lower urinary tract stones; Cystitis
Nosological classification ICD-10 (code)
N03;N11;N20;N21;N30
Type of dosage form
Dragee
Heat labile drug
No
Tradename
Canephron N
Trade name in Latin
Zincteral
Active ingredients
Lovage root, rosemary leaves, centaury herb
Diseases:
Cystitis and urethritis
Amount in a package
60
Pharmacological group ATS (name)
Other drugs for the treatment of urological diseases
Pharmacological group ATS (code)
G04BX
Conditions for dispensing from pharmacies
Over the counter
Country of Origin:
Germany
Type of packaging
Cardboard pack
Manufacturer Latin
Bionorica
Floor
Male, Female
Keep away from children
Yes
Organs and systems:
Urinary system and skin
Indications for use:
Glomerulonephritis, Cystitis, Pyelonephritis, Nephritis
Target age
Elderly, Child, Middle, Adult, Teenage
Manufacturer:
Bionorics
Type of product
Medicine
Brand Latin
Canephron N
Brand
Canephron N
Minimum age from, months
72
Canephron N price
How much does Canephron cost in Ukraine?
The price of Canephron N tablets No. 60 is from 120 UAH, the price of Canephron N drops is from 109 UAH.
At the same time, the price of Canephron N in Kharkov, Kyiv, Donetsk, Odessa or Dnepropetrovsk is not fundamentally different.
Cost of tablets and drops in Russia
You can buy Canephron in tablets in Moscow and other large cities of Russia for an average of 370 rubles. The price of the solution is from 350 to 420 rubles.
The drug has only 2 forms of release - pills and solution for oral administration, other forms (suppositories, solution in ampoules for injection, etc.) are not available.
The drug is often prescribed during pregnancy (that is, for long-term use). A more economical option is a solution, but most pregnant women do not risk taking it due to the presence of ethanol in it.
In this regard, women often wonder if there are more economical packages of tablets (for example, No. 120). The answer to this question is negative.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Canephron N tab.
p/o No. 60 Rottendorf Pharma GmbH/ Bionorica SE 592 rub. order - Canephron N solution for internal use. approx. 100mlBionorica SE
RUR 551 order
- Canephron N tab. p/o 120 pcs Rottendorf Pharma GmbH/ Bionorica SE
1104 rub. order
Pharmacy Dialogue
- Canephron N tablets No. 60Bionorica
605 rub. order
- Canephron N (tab. vol. No. 120) Rottendorf Pharma GmbH/Merz Pharma GmbH and Co. KGaA
RUB 1,155 order
- Canephron N bottle 100mlBionorica
RUR 533 order
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Pharmacy24
- Canephron N 100 ml oral drops Bionorika SE, Nimechchina
189 UAH order - Canephron N N60 tablets Bionorica SE, Nimechchina
215 UAH order
PaniPharmacy
- Canephron H tablets Canephron N film-coated tablets No. 60 Germany, Bionorica
233 UAH order
- Canephron H liquid Canephron N drops 100ml Germany, Bionorica
203 UAH order
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