From this article you will learn:
- What does Solcoseryl ointment help with?
- indications and regimens for use,
- application in cosmetology against wrinkles.
The article was written by a specialist with higher medical education.
Solcoseryl ointment is a preparation containing deproteinized dialysate from the blood of calves, which is an effective stimulator of healing of skin lesions and the red border of the lips. Here you need to pay attention to the fact that the drug is intended for application only to those wounds that do not have wet discharge. If the wound surface is wet or has discharge, in this case only Solcoseryl in gel form should be used.
The drug is registered as a “medicine” and is intended exclusively for external use. The drug is produced by pharma (Switzerland) and has no age restrictions, and is also not contraindicated for use in lactating and pregnant women. The latter indicates a high safety profile and a low risk of developing allergies. The ointment is a homogeneous white fatty mass, which has a characteristic smell of petroleum jelly and meat broth (the latter is associated with production technology).
Photo of the drug –
Compound
The solution for injection contains 42.5 mg/ml hemoderivate (extract) from calf blood as an active substance and water for injection (Aqua pro injectionibus) as an auxiliary component.
One gram of eye gel contains 8.3 g of active substance and auxiliary ingredients: sodium carboxymethyl cellulose (Sodium carboxymethyl cellulose), sorbitol (Sorbitol), water for injection (Aqua pro injectionibus), benzalkonium chloride (Benzalkonii chloridum).
One gram ointment contains 2.07 mg of active substance and a number of auxiliary components: methyl parahydroxybenzoate (E 218; Methyl parahydroxybenzoate), propyl parahydroxybenzoate (E 216; Propyl parahydroxybenzoate), cetyl alcohol (Cetyl spiritus), cholesterol (Cholesterol), white petroleum jelly ( Vaselinum album), water for injection (Aqua pro injectionibus).
One gram of jelly contains 4.15 mg of active substance and a number of auxiliary components: methyl parahydroxybenzoate (E 218; Methyl parahydroxybenzoate), propyl parahydroxybenzoate (E 216; Propyl parahydroxybenzoate), propylene glycol (Propylene glycol), carboxymethyl cellulose sodium salt (Sodium carboxymethyl cellulose), water for injection (Aqua pro injectionibus), calcium lactate pentahydrate (Calcii lactas pentahydrate).
Which is cheaper: Actovegin or Solcoseryl
Actovegin is a complete analogue of Solcoseryl. Its active ingredient is deproteinized calf blood dialysate. The release forms of Actovegin do not differ from those in which Solcoseryl can be found. Tablets and ampoules for intravenous administration are prescribed for the same indications. Actovegin is a prescription drug, like Solcoseryl. Therefore, they can be considered as the same substance, sold under different names. This means that when one of them is not available in the pharmacy, the pharmacist has every right to offer an analogue as a replacement. However, when comparing price categories, Solcoseryl should be given preference, because its cost is lower than Actovegina.
pharmachologic effect
Solcoseryl is a medicine that affects mainly metabolic processes in tissues. They activate tissue metabolic processes , improve trophism and stimulate tissue repair and when exposed to damaging factors.
Solcoseryl in injection form belongs to the pharmacotherapeutic group “ Hemodialysates and hemofiltrates ”, ointment and jelly - to the category of drugs used to treat wounds and ulcers (including poorly healing ones), gel - to the category of drugs used to treat ophthalmological diseases .
Pharmacodynamics and pharmacokinetics
The main component of Solcoseryl preparations are fractions of the blood of calves with natural low-molecular substances included in their composition, the molecular weight of which does not exceed 5 thousand daltons.
To date, its properties have only been partially studied. In vitro tests, as well as preclinical and clinical studies, have shown that calf blood extract:
- promotes the restoration and/or maintenance of aerobic metabolism and oxidative phosphorylation processes, and also ensures the replenishment of cells that do not receive sufficient nutrition with high-energy phosphates;
- in vitro enhances the utilization of oxygen and activates the transport of glucose into tissues and cells hypoxia and ;
- helps improve repair and regeneration processes in damaged tissues that do not receive sufficient nutrition;
- prevents the development or reduces the severity of secondary degradation and pathological changes in reversibly damaged cells and cellular systems ;
- in in vitro models activates collagen synthesis ;
- has a stimulating effect on the proliferation (reproduction) of cells and their migration (in in vitro models).
Thus, Solcoseryl protects tissues that are in a state of oxygen starvation and nutritional deficiency, and accelerates the processes of their restoration and healing.
Solcoseryl eye gel is a dosage form that was developed specifically for the treatment of lesions with troma of the cornea .
The gel-like consistency of the product ensures its uniform distribution on the cornea , and good adhesive properties allow it to remain on it for a long period of time. The use of eye gel accelerates the restoration of damaged tissues and prevents scarring.
The rate and extent of absorption, distribution, as well as the rate and route of elimination of the active substance from the patient’s body cannot be determined using conventional pharmacokinetic methods, since protein-free calf blood extract has pharmacodynamic effects that are characteristic of molecules with different chemical and physical properties.
In the process of studying the pharmacokinetic characteristics of Solcoseryl solution in animals, it was found that after a bolus injection, the effect of the drug develops within half an hour. The effect lasts for three hours after administration of the solution.
Description of the drug
Solcoseryl ointment is a pharmaceutical preparation synthesized by isolating components from the blood, i.e. This is a deproteinized dialysate. The drug in question does not have proteins and antigenic parameters, and the composition is saturated with natural substances, thanks to which liniment easily penetrates deep tissue structures.
The extract from the blood is the catalyst for biochemical processes that increase the saturation of the epidermis with active oxygen. The effect is enhanced by the activation of blood flow to the site of application of the composition. As a result, the skin is actively restored and regenerated.
pharmachologic effect
Solcoseryl cream is a hemodialysate with a large amount of blood serum of dairy calves and low molecular weight compounds. The chemical properties of the listed components have not been fully studied. However, it has been clinically proven that the medication is capable of:
- increases the rate of proliferation and cell migration;
- activates the production of collagen fibers;
- promotes the formation of granulation tissue;
- saturates metabolic exhausted cells with glucose;
- stimulates cellular regeneration, oxidative phosphorylation.
Solcoseryl is fat-free, which facilitates rapid removal from the skin surface by rinsing. Auxiliary ingredients form a protective film on damaged areas of the skin. To enhance the effect, it is recommended to take vitamins A and E.
Release form and composition
To rejuvenate the skin and smooth out age-related wrinkles, it is recommended to use the medicine in the form of an ointment or gel, due to its ease of application. Clotrimazole is available in several forms:
- gel (10%) – applied externally, available in 20 g metal tubes in cardboard packaging, instructions for use included;
- ointment (5%) - used only externally, available in 20 g aluminum tubes, cardboard packaging with instructions for use.
There are also highly specialized forms of release of the drug - ophthalmic gel, dental ointment.
The drug solcoseryl is available in different forms. Composition of the pharmaceutical product:
- gel – blood dialysate, calcium lactate, propylene glycol, carmellose sodium;
- ointment - extract from the blood of calves, medical petroleum jelly, cholesterol, cetyl alcohol.
Before using the medication, you must read the instructions, recommendations for application, contraindications and side effects. You cannot use other forms of the drug for anti-aging procedures.
Indications for use
Solcoseryl injections: what are they for and what groups of patients are they prescribed for?
Solcoseryl in ampoules is indicated for patients who have been diagnosed with occlusive peripheral artery disease of the third or fourth degree according to the Fontaine classification and who have contraindications or intolerance to other vasoactive drugs .
It is also prescribed to patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , as well as to patients with disorders of cerebral metabolism .
What is Solcoseryl ointment and jelly for?
The use of ointment and jelly is advisable for the treatment of minor injuries (for example, abrasions or cuts), frostbite, first and second degree burns (thermal or solar), difficult-to-heal wounds (for example, trophic skin disorders of venous etiology or bedsores ).
Indications for use of eye gel
Solcoseryl eye gel is recommended:
- for the treatment of mechanical injuries and erosive damage to the cornea and conjunctiva ;
- to accelerate the healing processes of postoperative scars in the postoperative period (for example, after a cornea transplant , surgery to remove a cloudy lens , surgical treatment of glaucoma , etc.);
- for the treatment of burns of the cornea of various origins (thermal, chemical or radiation);
- for the treatment of ulcerative lesions of the cornea and keratitis of various etiologies ;
- for dystrophic lesions of the cornea of various etiologies, including neuroparalytic keratitis , endothelial-epithelial dystrophy ( bullous keratopathy ), etc.;
- for the treatment of corneal xerophthalmia with lagofatalmos (non-closure of the palpebral fissure);
- to improve the tolerability of contact lenses and reduce the time of adaptation to them.
Indications for use of Solcoseryl dragees
The drug in the form of pills is taken to treat trophic and radiation ulcers , bedsores , gangrene , and chronic venous insufficiency . They are also prescribed to patients with gastric and duodenal ulcers and patients who require skin and/or corneal transplantation .
What is it used for?
Solcoseryl is used to accelerate the process of restoration of the skin in case of various injuries, burns, ulcers, frostbite. The product helps eliminate the effects of acne.
In surgery, the drug is prescribed for speedy healing of sutures, treatment of bedsores and impaired venous outflow in the lower extremities. A special eye form is used to eliminate ophthalmic pathologies. In dentistry, stomatitis and periodontal damage are treated with medicine.
Due to its pronounced regenerating effect, Solcoseryl ointment and gel are successfully used in home and professional cosmetology as a component of anti-aging products.
Contraindications
Administration of the solution is contraindicated in patients with known hypersensitivity to calf blood dialysates. The solution is also contraindicated for atopy and for persons allergic to milk .
Since the ointment, jelly and solution contain derivatives of parahydroxybenzoic acid , which are used as preservatives, as well as trace concentrations of benzoic acid in free form, it is not used in the presence of allergic reactions to the above substances.
With caution, ointment and jelly are prescribed to persons with a predisposition to allergic reactions .
A contraindication to the use of eye gel is hypersensitivity to its components. Since the eye gel can cause temporary visual impairment, you should not drive a car or operate potentially dangerous machinery for half an hour after its use.
Interaction
Solcoseryl injections should not be mixed when administered with other medications, especially with phytoextracts.
The pharmaceutical incompatibility of Solcoseryl in the form of an injection solution with parenteral forms has been established:
Ginkgo biloba extract,
naftidrofuryl,
bencyclane fumarate.
As solutions for diluting Solcoseryl injection, only isotonic sodium chloride solution and 5% glucose solution should be used.
The interaction of Solcoseryl with other topical medications has not been established.
Side effects
Administration of Solcoseryl IV or IM in very rare cases (their frequency does not exceed 0.1%) provokes the development of allergic or anaphylactic reactions , which are most likely caused by class E immunoglobulins .
If body temperature rises, urticaria , swelling and hyperemia at the site of drug administration, the use of Solcoseryl is stopped, and symptomatic treatment will be prescribed to eliminate the symptoms that appear.
Since the solution contains potassium, its administration may cause pain at the injection site.
When using Solcoseryl cream, a short-term burning sensation may be felt at the site of application. Discontinuation of the drug is required only in cases where the unpleasant sensation does not disappear for a long period of time.
In isolated cases, the use of jelly and ointment can cause the development of allergic reactions . If allergy symptoms , the use of these products should be discontinued.
Toxicological studies of Solcoseryl eye gel have shown the high safety of this drug when used for its intended purpose in accordance with the instructions.
After instillation of the product, a short-term burning sensation and mild irritation may be observed, which are not reasons for stopping treatment. Repeated instillation in rare cases provokes the development of allergic reactions (a similar effect is also observed during treatment with other ophthalmic drugs for topical use).
Instructions for use of Solcoseryl (Method and dosage)
Solution for injection: instructions for use
In cases where the patient's condition allows, the drug is recommended to be used in the form of an injection solution diluted at least 50:50 with saline or glucose solution .
Solcoseryl in ampoules is intended for slow administration in the form of intravenous injections or infusions. If intravenous administration is not possible, the drug can be injected into the muscle.
Since the drug in its pure form is a hypertonic solution, it should be administered slowly.
For intravenous infusion, the drug should be pre-diluted with 0.25 l of 0.9% NaCl solution or 5% glucose solution . Solcoseryl solution is administered intravenously by drip. The rate of administration depends on the hemodynamic status of the patient.
Patients with occlusive disease of peripheral arteries of the third or fourth degree according to the Fontaine classification are shown daily injection into a vein of 0.85 g (or 20 ml of undiluted solution) Solcoseryl.
The duration of use is usually up to four weeks and depends on the clinical situation.
Patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , are indicated for intravenous administration of 0.425 g (or 10 ml of undiluted solution) Solcoseryl three times a week.
The duration of the course of treatment should not exceed four weeks (it is determined depending on the nature of the disease).
To prevent the appearance of peripheral “venous” edema , therapy is supplemented by applying a pressure bandage using an elastic bandage. If the patient has skin trophic disorders, treatment is carried out by combining injections or infusions of Solcoseryl solution with the use of jelly, and then ointment.
Patients who have suffered ischemic or hemorrhagic stroke are prescribed daily intravenous administration of 0.425 or 0.85 g of Solcoseryl (10 or 20 ml of undiluted solution) as the main course. The duration of the main course is 10 days.
Further treatment involves daily administration of 85 mg (or 2 ml of undiluted solution) Solcoseryl for one month.
In severe forms of brain contusions, daily injection of 1000 mg of Solcoseryl into a vein (corresponding to 23-24 ml of undiluted solution) is prescribed for 5 days.
The drug is administered intramuscularly undiluted at a dose of 2 ml/day.
Solcoseryl jelly and ointment: instructions for use
Cream and ointment are intended for application directly to the wound surface. Before using these dosage forms, the wound is first cleaned using a disinfectant solution.
Patients with trophic ulcers , as well as in cases of purulent infection of wounds , require preliminary surgical treatment before starting treatment.
When using jelly and ointment for frostbite , as well as for the treatment of ulcers and skin injuries , it is important to remember that only sterile dressings should be used to treat damaged areas.
The gel is intended for application to fresh (including wet) wounds and weeping ulcers . The product is applied in a thin layer to a previously cleaned wound surface two or three times a day.
To treat areas where epithelization has begun, the use of ointment is indicated. The use of jelly is advisable until pronounced granulation tissue begins to form on the damaged surface of the skin and the wound begins to dry out.
The ointment is used primarily for the treatment of dry (without weeping) wounds . The product is applied in a thin layer to a previously cleaned wound surface once or twice a day. If necessary, cover the treated surface with a bandage.
The course of treatment with the drug in this dosage form continues until the wound heals and is completely healed with elastic tissue.
For patients with severe trophic damage to the skin and soft tissues, it is recommended to combine jelly and ointment with the injection form of Solcoseryl.
Experience with the use of jelly and ointment for children is limited.
The drug does not have such release forms as suppositories. However, in the complex therapy of chronic colitis (inflammation of the colon), microenemas with Solcoseryl jelly are often prescribed.
Before use, the jelly contained in the tube (all 20 g) is added to 30 ml of warm water and after the enema procedure, which is carried out to cleanse the intestines , it is administered daily for 10 days.
Solcoseryl eye gel: instructions for use
Unless otherwise instructed by the attending physician, the eye gel is instilled into the conjunctival cavity , one drop three or four times a day. It is recommended to use the product daily until complete recovery.
In particularly difficult cases, eye ointment can be used one drop per hour. If the patient is simultaneously prescribed eye drops and Solcoseryl eye gel, the gel should be applied approximately half an hour after the drops.
During the period of adaptation to contact lenses, the drug is instilled into the conjunctival cavity immediately before installing the lenses and immediately after removing them.
Dragee Solcoseryl: instructions for use
The instructions recommend taking 100 mg tablets three times a day.
How to inject Solcoseryl for gastritis
Gastritis is a disease of the gastric mucosa that can occur for various reasons. Solcoseryl ampoules will not become the main drug used in the treatment of gastritis, but it can speed up the healing process, while the prescribed therapy will relieve the patient of the source of the problem.
The gastric mucosa can become inflamed not only as a result of poor nutrition, but also as a result of infection with gastrointestinal infections. The attending physician will first conduct an examination and evaluate the test results, which will allow him to prescribe effective therapy. Solcoseryl will be used as an addition to the main treatment, as it will help the stomach tissues to regenerate faster, ulcers to heal, and inflammation to disappear.
special instructions
Studies regarding the safety of using Solcoseryl solution for the treatment of children have not been conducted, therefore the drug is not recommended for the treatment of children under the age of 18 years.
Experience in treating children with the use of eye gel and topical dosage forms of the drug is also limited.
Solcoseryl in ampoules should be administered separately from other drugs (it is especially incompatible with phytoextracts). The exceptions are isotonic 0.9% NaCl solution and 5% glucose solution . It is also not recommended to dilute the product in potassium-containing solutions for infusion.
Eye gels are characterized by the ability to stick to contact lenses, so it is recommended to stop wearing lenses during treatment with the drug.
If allergic reactions associated with the use of the drug, you should immediately report them to your doctor. If the drug is used to treat an infectious disease of the cornea , therapy is supplemented with the prescription of appropriate antimicrobial agents .
Avoid contact of the gel with soft contact lenses as it may discolor them.
If necessary, treatment with Solcoseryl can be supplemented with antibacterial , vasodilating and other drugs.
Solcoseryl in cosmetology: for the face, hands, rough elbows and heels, for the skin around the eyes
In medicine, Solcoseryl preparations are used to accelerate the healing of damaged skin; in home cosmetology, they are used as a remedy for acne, stretch marks, and wrinkles. They are used to soften the skin, increase its turgor, improve complexion and eliminate acne .
In cosmetology, the ointment can be used as a stand-alone product (it is applied pointwise to problem areas, in the form of a mask once a week before bedtime and two to three times a week on the skin around the eyes), or in combination with other products, in particular with the drug Dimexide . Let's look at how to use these medications together.
For the face, Dimexide and Solcoseryl are used as follows: on the face, neck and décolleté, previously cleaned with peeling agents (you can also do alkaline peeling using tar soap, salt and soda), apply a solution of Dimexide with water, prepared in a ratio of 1:10 (enough dilute 5 ml (teaspoon) of Dimexide in 50 ml of water); Before the product has time to be absorbed, Solcoseryl ointment is applied to it in a thick layer.
If the gel is used in cosmetology, then the mask should be periodically sprayed with thermal water (you can also use regular water through a spray bottle). The mask is left on the face for about half an hour to an hour, then washed off and a light hypoallergenic cream is applied to the skin.
According to women who have tried this mask recipe on themselves, Solcoseryl ointment is more comfortable for the face than gel (after application, you don’t have to wash it off, just remove the residue with a napkin). In addition, it is not recommended to use a gel mask more than once a month.
Used as a remedy for wrinkles around the eyes, Solcoseryl ointment has proven itself to be a very effective remedy. Applying it like a regular cream, within a week you can see that the number of wrinkles and wrinkles has decreased, the skin has tightened and smoothed, and its color has become fresher and healthier.
Dimexide and Solcoseryl are no less effective against wrinkles, and perhaps even more effective. This is due to the ability of Dimexide to enhance the penetration of the active substance of drugs deep into the tissue. After using these products in combination, skin irregularities and imperfections disappear, and the effect of the mask is comparable to the effect of Botox .
The gel and ointment can also be used to soften rough skin on the elbows and heels. It is best to apply them to problem areas before bed.
Mask with Dimexide and Solcoseryl
Solcoseryl for the face against wrinkles (reviews from cosmetologists guarantee the effectiveness of the ointment) works more actively together with Dimexide. This is explained by the fact that Dimexide promotes the transport of Solcoseryl into the deep layers of the skin, thereby enhancing the effect of the drug.
To prepare a mask of Solcoseryl with Dimexide you will need:
- 1 ml dimexide;
- 10 ml boiled water;
- Solcoseryl ointment or gel.
Dimexide must be dissolved in water. Then you should moisten a cotton pad in the resulting mixture and apply it to cleansed facial skin. After this, it is necessary to apply Solcoseryl to the face so that the skin is not visible. Then the drug is left to act for 1 hour.
After the period has passed, remove it with a damp cotton pad. After such a mask, the skin takes on a rested appearance, it is deeply moisturized, its elasticity increases, and fine wrinkles are smoothed out. This mask is suitable for aged and depleted skin.
Analogues of Solcoseryl
Level 4 ATX code matches:
Badyaga Forte
Badyaga
Rogaine
Capsiol
Vulnuzan
Skin cap
Petrolatum
Generolon
Alerana
Apilak
Tsinocap
Silocast
Analogs of Solcoseryl: Aekol , Acerbin , Bepanten , Shostakovsky balm , Vundehil , Depantol , Contractubex , Pantekrem , Pantexol Yadran , Panthenol , Pantestin , Hepiderm Plus , Echinatsin Madaus .
Reviews of Solcoseryl
Almost all reviews left on the forums about injections, eye gel, jelly and Solcoseryl ointment are positive. Rare negative reviews are due largely to the fact that the drug provoked allergic reactions associated with intolerance to its active component.
Reviews of Solcoseryl gel and the drug in the form of an ointment allow us to conclude that these drugs effectively cope not only with minor scratches and minor burns, but also help cure difficult-to-heal wounds and ulcers .
The average rating of a drug on sites where people share their impressions of certain drugs is 4.8 on a 5-point scale.
The effectiveness of the ointment in cosmetology is also highly appreciated. Reviews of Solcoseryl ointment for the face indicate that this is truly an indispensable product for those who want to quickly get rid of wrinkles, acne, and simply improve the color and tone of the skin.
Gel is no less effective against wrinkles, but cosmetologists believe that it should not be used as part of masks too often (optimally - once a month). The ointment can be used as a regular cream.
The effectiveness of Solcoseryl against wrinkles increases when combined with Dimexide, which is due to the latter’s ability to improve the penetration of the active substance deeper into the skin.
Efficiency
Solcoseryl for the face against wrinkles (reviews from cosmetologists prove its effectiveness) is often used. The result quickly becomes noticeable. Usually, after the first 2-3 applications, positive dynamics are noticeable.
After a course of use, existing wrinkles are noticeably smoothed out, and the facial contours are evened out.
The skin becomes softer and more hydrated, and its color becomes even. The high effectiveness of this drug is explained by the fact that it is able to enrich skin cells with oxygen and regulate the production of the skin’s own collagen. Also, the use of Solcoseryl helps to get rid of inflammation that occurs on the skin.
Solcoseryl price, where to buy
How much does Solcoseryl cost in Ukraine?
The average price of Solcoseryl in ampoules in Ukrainian pharmacies is from 265 to 515 UAH (depending on the volume of ampoules and their number in the package). The price of Solcoseryl ointment in Ukraine is 57-60 UAH. You can buy jelly for an average of 52 UAH. Eye cream costs on average from 60 to 74 UAH.
Cost of the drug in Russia
The price for Solcoseryl injections in Russian pharmacies varies from 400 to 1300 rubles (depending on the volume of ampoules and their number in the package). The price of Solcoseryl gel (which can be used as an anti-wrinkle gel) is 180-200 rubles. The price of the eye gel is 290-325 rubles. Pharmacies provide information on the price of tablets upon request.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
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