Genferon Light suppositories 250,000 IU + 5 mg No. 10 - buy in Moscow, price in pharmacies from 541 rubles, instructions for use, reviews

Genferon Light

GENFERON® LITE 250 thousand IU. – the only combination of interferon alpha-2b and taurine1 in Russia for the treatment of acute respiratory diseases of viral and bacterial etiology in adults and children over 7 years of age, as well as for the treatment of urogenital tract infections in women, incl. at 13-40 weeks of pregnancy2

Features of the composition and properties of the components of suppositories GENFERON® LITE 250 thousand IU:

a unique combination drug1, the complex therapeutic effect of which is determined by the components included in its composition: recombinant interferon alpha-2b has a universal3 direct antiviral, immunomodulatory, antiproliferative and indirect antibacterial effect2;
taurine is a strong antioxidant, helps normalize metabolic processes and tissue regeneration, has anti-inflammatory4, membrane-stabilizing and immunomodulatory effects; also helps maintain the biological activity of interferon, enhancing the therapeutic effect of the drug2;

achieving the maximum concentration of interferon in the blood serum with rectal administration of the drug within 5 hours after its use2;

due to the long half-life (within 12 hours), the possibility of using the drug twice a day2;

mutual potentiation of action and enhancement of the total therapeutic effect when combined with antibacterial, antiviral and antifungal drugs2.

Features of the release form - suppositories GENFERON® LIGHT 250 thousand IU:

suppositories for vaginal and rectal use: possibility of rectal use in pediatric practice
the ability to control the medicinal properties and therapeutic effect of the drug when used in women of reproductive age: with rectal administration of the drug, high bioavailability (more than 80%) of interferon is achieved, and therefore provides a pronounced systemic immunomodulatory effect2;
when used intravaginally , due to the high concentration at the site of infection and fixation on the cells of the mucous membrane, a pronounced local antiviral, antiproliferative and antibacterial effect is achieved2.

reduced cross-sectional size of the suppository** – for more comfortable and painless administration of the drug;

The suppository base is solid fat with low allergenic potential4,5;

Indications for the use of suppositories GENFERON® LITE 250 thousand IU:

as a component of complex therapy – for the treatment of acute respiratory viral infections and other acute infectious diseases of bacterial and viral etiology in adults and children over 7 years of age;
in complex therapy of chronic infectious and inflammatory diseases of viral etiology in children over 7 years of age;
for the treatment of infectious and inflammatory diseases of the urogenital tract against the background of specific therapy prescribed and supervised by a physician in: children over 7 years of age;
pregnant women at a period of 13–40 weeks (II-III trimesters of pregnancy);
women of all ages.

Genferon Light suppositories 250000IU+5mg No. 10

A country

Russia
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.

Active substance

Interferon alpha-2b + Taurine

Compound

Interferon alpha-2b, taurine.

pharmachologic effect

Has local and systemic effects. The drug contains recombinant human interferon alpha-2b. Interferon alpha-2b has antiviral, immunomodulatory, antiproliferative and antibacterial effects. The immunomodulatory effect is manifested, first of all, by enhancing cell-mediated reactions of the immune system, which increases the effectiveness of the immune response against viruses, intracellular parasites and cells that have undergone tumor transformation. Activation under the influence of interferon of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of pathological foci; in addition, due to the influence of interferon, restoration of the production of secretory immunoglobulin A is achieved. The antibacterial effect is mediated by reactions of the immune system, enhanced under the influence of interferon. Taurine helps to normalize metabolic processes and tissue regeneration, has a membrane-stabilizing and immunomodulatory effect. Taurine helps maintain the biological activity of interferon, enhancing the therapeutic effect of the drug. With rectal administration of the drug, high bioavailability of interferon is observed, and therefore both local and pronounced systemic immunomodulatory effects are achieved; when used intravaginally, due to the high concentration at the site of infection and fixation on the cells of the mucous membrane, a pronounced local antiviral, antiproliferative and antibacterial effect is achieved, while the systemic effect is insignificant due to the low absorption capacity of the vaginal mucosa. The maximum concentration of interferon in the blood serum is achieved 5 hours after administration of the drug. The main route of elimination of α-interferon is renal catabolism. The half-life is 12 hours, which necessitates the use of the drug 2 times a day.

Indications for use

For the treatment of infectious and inflammatory diseases of the urogenital tract in children and women, including pregnant women. As a component of complex therapy - for the treatment of other infectious diseases of viral etiology.

Interaction

The drug is most effective as a component of complex therapy. When combined with antibacterial, fungicidal and antiviral drugs, mutual potentiation of action is observed, which makes it possible to achieve a high total therapeutic effect

Side effect

Local allergic reactions (itching and burning sensation in the vagina). These phenomena are reversible and disappear within 72 hours after cessation of administration. Continuation of treatment is possible after consultation with a doctor. Phenomena that occur when using all types of interferon alfa-2b may be observed, such as chills, fever, fatigue, loss of appetite, muscle and headaches, joint pain, sweating, as well as leukemia and thrombocytopenia. In these cases, it is recommended to consult your doctor to decide whether to discontinue the drug or reduce the dose.

Contraindications

Individual intolerance to interferon and other substances included in the drug. With caution: Exacerbation of allergic and autoimmune diseases. Use during pregnancy and lactation: Clinical studies have proven the effectiveness and safety of the drug in the second and third trimesters of pregnancy. The safety of using the drug in the first trimester of pregnancy has not been studied.

Overdose

If you accidentally administer more suppositories at a time than were prescribed by your doctor, further administration should be suspended for 24 hours, after which treatment can be resumed according to the prescribed regimen.

special instructions

The drug does not affect the performance of potentially hazardous activities that require special attention and quick reactions (driving vehicles, machinery, etc.).

Dispensing conditions in pharmacies

On prescription

Genferon suppositories No. 10 55 mg+1 million IU+10 mg

GENFERON is a combination drug, the effect of which is determined by the components included in its composition. Has local and systemic effects.

The drug Genferon includes recombinant human interferon alpha-2b, produced by a strain of the bacterium Escherichia coli, into which the human interferon alpha-2b gene has been introduced using genetic engineering methods.

Interferon alpha-2b has antiviral, immunomodulatory, antiproliferative and antibacterial effects. The antiviral effect is mediated by the activation of a number of intracellular enzymes that inhibit viral replication. The immunomodulatory effect is manifested, first of all, by enhancing cell-mediated reactions of the immune system, which increases the effectiveness of the immune response against viruses, intracellular parasites and cells that have undergone tumor transformation. This is achieved through the activation of CD8+ T killer cells, NK cells (natural killer cells), increased differentiation of B lymphocytes and their production of antibodies, activation of the monocyte-macrophage system and phagocytosis, as well as increased expression of molecules of the major histocompatibility complex type I, which increases the likelihood recognition of infected cells by cells of the immune system. Activation of leukocytes contained in all layers of the mucous membrane under the influence of interferon ensures their active participation in the elimination of pathological foci; in addition, due to the influence of interferon, the production of secretory immunoglobulin A is restored. The antibacterial effect is mediated by reactions of the immune system, enhanced under the influence of interferon.

Taurine helps normalize metabolic processes and tissue regeneration, has membrane-stabilizing and immunomodulatory effects. Being a strong antioxidant, taurine directly interacts with reactive oxygen species, the excessive accumulation of which contributes to the development of pathological processes. Taurine helps maintain the biological activity of interferon, enhancing the therapeutic effect of the drug.

Benzocaine (anesthetic) is a local anesthetic. Reduces the permeability of the cell membrane to sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, and blocks the conduction of nerve impulses. Prevents the occurrence of pain impulses at the endings of sensory nerves and their conduction along nerve fibers. It has an exclusively local effect, without being absorbed into the systemic circulation.

Genferon Light suppositories 125000IU+5mg No. 10