How to beat the flu: the basics of vaccination in five questions

Influenza vaccine (inactivated)

The vaccine for the prevention of influenza is inactivated, trivalent. Pharmacological group – MIBP vaccine

Manufacturers: FSUE SPbNIIVS FMBA (Russia), Branch of the Federal State Institution “48 Central Research Institute of the Ministry of Defense of the Russian Federation” - “Virological Center” (Russia). Owner of the registration certificate: FORT LLC.

Protects against: Influenza caused by an identified influenza virus.

Applicable to: children over 6 months of age, adolescents and adults

Not included in the national vaccination calendar.

Indications for Ultrix vaccination

• Specific prevention of influenza in children from 6 months of age, adolescents and adults without age restrictions.

The vaccine is especially indicated

• Children attending kindergarten and school who have a high probability of contracting the flu in the children's group.
• Children and adults who have a high risk of complications in case of influenza: those who often suffer from acute respiratory infections and acute respiratory viral infections, those suffering from chronic somatic diseases, incl. diseases and malformations of the central nervous system, cardiovascular system and bronchopulmonary system, bronchial asthma, chronic kidney disease, diabetes mellitus, metabolic diseases, autoimmune diseases, allergic diseases (except allergy to chicken protein), chronic anemia, congenital or acquired immunodeficiency , HIV-infected;
• elderly people over 60 years old (grandparents)

The vaccine is indicated for everyone who, due to the nature of their work, communicates with a large number of people:

• Those who, by virtue of their profession, have a high risk of contracting the flu or infecting others with it: doctors, nurses and other health care workers; teachers and other employees of educational institutions; employees of the social services sector, transport, trade, police, and military personnel.

What contraindications exist for Ultrix Quadri?

Vaccination should be postponed if the child is ill in the acute stage, for a period of 2 to 4 weeks - it is better to consult with your personal pediatrician about the necessary break. For mild respiratory or intestinal infections, you need to wait until the temperature drops, then, as a rule, you can get vaccinated. The vaccine should not be given if the child has had a strong reaction to previous flu vaccinations (no matter what kind of vaccine) or is allergic to any of the components, including chicken protein.

Patients who have recovered from covid-19 can be vaccinated against influenza 1 month after recovery.

Sources:

1. Instructions for use of the Ultrix Quadri vaccine
2. Rostec’s vaccine against four strains of influenza “Ultrix Quadri” has been approved for all ages.//Rostec, 09/21/2021
3. Creator of the new Russian flu vaccine Anton Katlinsky: We vaccinated Sergei Chemezov and Veronika Skvortsova.//Snob, 10/15/2019

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Contraindications

Only a doctor can decide whether Ultrix is ​​suitable for vaccination

The Ultrix vaccine is contraindicated if there is a history of an allergic reaction to any component of the vaccine and in the following cases:

• allergic reactions to chicken protein and vaccine components;
• allergic reactions to previously administered influenza vaccines;
• acute febrile conditions or exacerbation of a chronic disease (vaccination is carried out after recovery or during remission);
• mild ARVI, acute intestinal diseases (vaccination is carried out after the temperature has normalized).

What is known about Ultrix Quadri?

This is an inactivated split vaccine containing antigens of influenza virus types A (H1N1 and H3N2) and B (Yamagata and Victoria lines). Thus, unlike the regular Ultrix, it is four-part. Vaccines of this type appeared in Russia 2 years ago, in 2021. They are considered more effective (as they protect against more varieties of influenza), but production capacity was initially sufficient only for risk groups (people with severe chronic diseases), so they became available to a wide range of patients relatively recently. It is now rated as one of the most reliable flu shots available to Russians. The vaccine was created by the Rostec state corporation.

special instructions

On the day of vaccination, those vaccinated must be examined by a doctor (paramedic) with mandatory thermometry. At temperatures above 37.0°C, vaccination is not carried out. The vaccinated person should be under the supervision of a health care worker for 30 minutes after immunization. The Ultrix vaccine does not affect the ability to drive a car or control machines and mechanisms.

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What is included in the Ultrix Quadri vaccine?

The exact composition of antigens, like other influenza vaccines, is updated annually in accordance with WHO recommendations. The dosage of each is at least 15 mcg, which is recommended by WHO. In addition to them directly, the drug contains only 3 components: polysorbate 80, widely used in the food industry as an emulsifier, octoxynol 10 as a stabilizer and phosphate buffer solution. Ultrix Quadri does not contain additional immune response enhancers, for which some other domestic drugs have been repeatedly criticized.

Possible side effects

Systemic reactions: possible - slight short-term increase in body temperature, fever, general malaise (these phenomena resolve on their own within 1-2 days); extremely rarely - neuralgia, paresthesia, convulsions, transient thrombocytopenia, neurological disorders, vasculitis.

Allergic reactions: in patients with known sensitivity to individual components of the vaccine - itching, urticaria, rash; extremely rare - severe allergic reactions such as anaphylactic shock.

Local reactions: soreness, redness and swelling at the site of vaccine administration. These adverse reactions develop on the day of vaccination, usually go away on their own within 1-3 days and do not require treatment.

Benefits of vaccination in any pediatric healthcare setting

RESPONSIBILITY FOR THE LIFE AND HEALTH OF THE PATIENT

• vaccination is carried out only in specially equipped and licensed pediatric medical centers
• all drugs used are approved for use on the territory of the Russian Federation and have the necessary certificates
• the quality of drugs, expiration dates and storage conditions are carefully controlled
• medical personnel performing vaccinations are certified as “vaccination nurses” and undergo regular additional training and certification
• Before vaccination with any vaccines, all patients are required to be examined by an immunoprophylaxis doctor. The purpose of the examination is to make sure that the patient’s body condition is normal, there are no contraindications or medical exemptions from vaccination, and there is no risk of developing post-vaccination complications.
• After vaccination, the patient must remain in the medical center for at least 30 minutes under the supervision of a vaccination nurse
• the next day after vaccination, the vaccination nurse will definitely call you, check your health status, and make sure that the vaccination was successful
• If necessary, or if post-vaccination complications develop, a pediatrician or immunoprophylaxis specialist will come to your home free of charge within 24 hours after vaccination and provide the necessary assistance.

Dear parents! Please check in advance for up-to-date information about the availability of the vaccine you need at the medical center by phone.

How to beat the flu: the basics of vaccination in five questions

05.11.2020

In Russia, as usual, mass flu vaccination started in September. This season it is especially important amid the coronavirus pandemic. Rostec's pharmaceutical holding Nacimbio is actively supplying anti-influenza vaccines - these are domestic drugs that have proven themselves well in past epidemic seasons. We tell you when and what to get vaccinated this fall and how seasonal flu vaccination is compatible with the new COVID-19 vaccine.

When should you get a flu shot?

Although the campaign against influenza has been going on since September, and October is considered the optimal time for prevention, November is not too late to get vaccinated. The peak of the spread of influenza usually occurs in the middle of winter, but even if the epidemic has already begun, vaccination will not be superfluous. A vaccine containing antigens from current influenza strains will “teach” the body to fight a real infection and help prevent the dangerous consequences of influenza.

Why do you need to get vaccinated every year?

The flu vaccine usually lasts for one epidemic season, approximately equal to a year. Therefore, the body’s resistance to the virus needs to be increased every year. Firstly, the immunity developed as a result of vaccination decreases over time. Secondly, different types of influenza circulate around the planet from year to year, and every year the World Health Organization (WHO) makes recommendations which strains of the virus will be most active this season. Based on this, national manufacturers are preparing appropriate vaccines.

For example, the Ultrix, Sovigripp and Flu-M vaccines supplied by Nacimbio, the pharmaceutical holding of the Rostec State Corporation, as part of the Russian National Vaccination Calendar for the 2020-2021 season, are trivalent, that is, they contain three current strains of the virus flu And the newest quadrivalent vaccine, Ultrix Quadri, which is in use for the second season, includes another additional strain of influenza B virus. According to WHO forecasts, three new strains of influenza will come to Russia this year, for which collective immunity has not yet been developed.

How do flu and COVID-19 vaccinations work together?

Unfortunately, with the onset of the cold season, residents of Russia may face the spread of two respiratory viruses at once - seasonal influenza and Covid. Doctors do not yet have much experience in treating these two diseases together. But the creators of the first domestic coronavirus vaccine from the National Research Center named after. N.F. The Gamaleyans have already stated that the Covid vaccine will not conflict in the body with the flu vaccine. It is recommended to maintain a gap of three weeks between the two drugs.

As you know, the flu is dangerous not by itself, but by complications after it. These complications can also aggravate the course of the coronavirus infection. And a body weakened by the influenza virus will be more susceptible to contracting Covid. In addition, the symptoms of the COVID-19 virus may resemble the common flu - aching joints, fever, cough. Therefore, this season it is very important to get a flu shot, so that if characteristic symptoms appear, there is a high probability of distinguishing flu from covid.

Who should get the flu vaccine?

This season in Russia it is planned to cover about 60% of the population with flu vaccination, including 75% of those at risk. It is the latter that vaccination is especially indicated.

Those at risk include children, pregnant women, people over 60 years of age, people with chronic diseases and healthcare workers. There are not many contraindications for vaccination. These are allergic reactions to chicken protein, on which the vaccine is based, and its other components, the presence of signs of acute respiratory infections and acute chronic diseases. If you are unsure of your allergic status, it is recommended to stay in a medical facility for 15 minutes after the injection to observe your body's reaction to the drug.

What to vaccinate in the 2020-2021 season?

Flu vaccines are included in the list of vital and essential drugs, therefore their production and supply are regulated at the state level. There is no fundamental difference between domestic and foreign vaccines, but only domestically produced anti-flu drugs are included in the National Preventive Vaccination Calendar. This year, Russian patients are being vaccinated with domestic vaccines, which have proven themselves well in previous seasons.

As part of the annual mass flu vaccination campaign, Rostec's pharmaceutical holding Nacimbio will supply more than 75 million doses of vaccines for children and adults. These are the trivalent vaccines “Ultrix”, “Sovigripp”, “Flu-M” and the quadrivalent vaccine “Ultrix Quadri”. The latter will be supplied with 7.5 million doses this time – 40% more than last season.

As of 2021, WHO recommends quadrivalent vaccines as a priority for the prevention of influenza worldwide. In Russia, a state program is being implemented for a phased transition to such drugs. The expanded strain composition of Ultrix Quadri this season eliminates possible risks associated with the emergence and circulation of the Victorian and Yamagata lines of influenza. The vaccine contains 15 micrograms of hemagglutinin (antigen) of each strain per dose and does not contain preservatives or adjuvants. Russia, according to state plans, will switch completely to vaccinations with four strains by 2023.

Our country is part of a narrow circle of states capable of producing quadrivalent influenza vaccines in a full cycle. The quality of the new Russian drug is evidenced by the fact that people want to be vaccinated with it not only in our country, but also abroad. According to Rostec CEO Sergei Chemezov, this year foreign customers will receive more than 1 million doses of Ultrix Quadri.

Other news

Epidemiologist Nikolai Briko: the situation with coronavirus in Russia is quite difficult

The coronavirus pandemic has forced doctors and scientists to reassess the situation with infectious diseases in Russia. In particular, in recent years, the country has seen an increase in the incidence of meningococcal infection, which indicates the importance of implementing measures to prevent it. Academician of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor Nikolai Briko spoke about which categories of citizens are most susceptible to meningococcal infection, the consequences of its combination with COVID-19, as well as the overall situation with coronavirus in the country.

Rospotrebnadzor warned about the danger of “chickenpox parties”

Some people believe that it is better to have chickenpox in childhood, because a child supposedly tolerates this disease more easily than an adult. Therefore, there are still parents who try to “plan” for the disease: they go to visit sick friends and organize “chickenpox parties,” Alexander Gorelov, deputy director for scientific work at the Central Research Institute of Epidemiology of Rospotrebnadzor, noted in an interview with Sputnik radio.

In the Nizhny Novgorod region, 1.5 million people were vaccinated against influenza

In the Nizhny Novgorod region, flu vaccination is being completed, the press service of the regional government reported. The vaccination campaign covered less than half of the region’s population—1.5 million people, including 388 thousand children and adolescents.

In Bashkiria they talked about the benefits of vaccination against pneumococcus

Does the pneumococcal vaccination make it easier to cope with coronavirus in case of complications? Important information was presented at a briefing on the results of the activities of the healthcare sector in Bashkiria in 2021. As Industry Minister Maxim Zabelin said, indeed, vaccination against pneumococcus reduces the incidence of complications from Covid and the development of bacterial pneumonia.

Rostec began supplying Russian flu vaccines abroad

In 2021, FORT exported vaccines to the Republic of Belarus, Moldova, Kyrgyzstan, Turkmenistan and Uzbekistan. In the overall structure of supplies, the largest volume (over 90%) fell on the quadrivalent vaccine Ultrix Quadri. In addition, foreign partners purchased the trivalent Ultrix vaccine.

Nacimbio launched an application about vaccinations

, which is managed by the Nacimbio holding of the Rostec State Corporation, launched the “Vaccinations - Personal Calendar” mobile application. It helps users create an individual vaccination schedule and reminds them about scheduled vaccinations. The Vaccinations app is available for free on Android and iOS mobile phones.

Covid-19 vaccines will be included in the preventive vaccination calendar

Prime Minister Mikhail Mishustin instructed to include vaccines against the new coronavirus infection in the calendar of preventive vaccinations for epidemic indications, taking into account priority. Previously, COVID-19 vaccines were included in the VED. Mishustin noted that changes to the order of the Ministry of Health “On approval of the National Calendar of Preventive Vaccinations and the Calendar of Preventive Vaccinations for Epidemic Indications” must be made before December 17, 2020.

Vaccination against coronavirus has begun in Crimea

“Vaccination begins today in Crimea. First of all, high-risk medical workers who work with patients with a new coronavirus infection will be vaccinated. In the future, the daily number of vaccinated people will depend on the volume of vaccine received,” wrote the head of the republic, Sergei Aksenov, on his page on the VKontakte social network.

Cases of dangerous measles continue to be recorded in the Volgograd region

In the Volgograd region in 2021, measles was laboratory confirmed. This was reported by the regional department of Rospotrebnadzor. It is known that a dangerous disease manifests itself in those who have not been vaccinated. This year, 1 case of measles was confirmed in the region.

Scientists will combine the Oxford vaccine with Sputnik V

Scientists from the University of Oxford and the Russian Gamaleya Research Center for Epidemiology and Epidemiology will join forces to work on a vaccine for COVID-19. They agreed to conduct clinical trials of a combination of two drugs - the British vaccine and one of the two components of the Russian Sputnik V, the Russian Direct Investment Fund and the Swedish-British pharmaceutical company AstraZeneca reported.

Additional Information

Is it possible to purchase Ultrix from us or where to buy Ultrix in Moscow?

The City of Childhood clinic on Taganka and Zhulebino does not sell the Ultrix vaccine, we vaccinate.

Where to get the Ultrix vaccination in Moscow?

You can get vaccinated with Ultrix at the City of Childhood clinic on Taganka and Zhulebino, the Ultrix vaccine is available. Vaccination requires a mandatory examination before vaccination, the vaccination itself and observation after vaccination.

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How to help your child feel comfortable during vaccinations

Vaccination works better when the baby is calm and not afraid. To avoid scaring your child, try the following:

• Distract and calm your baby, hug him, talk softly to him
• Be calm, confident, smile. Maintain eye contact with your child, communicate with him, show him that you are nearby and everything is okay.
• Let your child hold a favorite toy or blanket.
• Ask your doctor if you can hold your baby on your lap and gently rub his back during vaccination.
• Be sure to praise your child after vaccination, tell him how great he is and how proud you are of him. Support your baby, even if he couldn't help but cry.

Influenza vaccine (inactivated)

The vaccine for the prevention of influenza is inactivated, trivalent. Pharmacological group – MIBP vaccine

Manufacturers: FSUE SPbNIIVS FMBA (Russia), Branch of the Federal State Institution “48 Central Research Institute of the Ministry of Defense of the Russian Federation” - “Virological Center” (Russia). Owner of the registration certificate: FORT LLC.

Protects against: Influenza caused by an identified influenza virus.

Applicable to: children over 6 months of age, adolescents and adults

Not included in the national vaccination calendar.