Analogues of Pulmicort in nebulas for inhalation through a nebulizer are Budesonide native and Budenit steri-neb, their price is 200 rubles lower per pack. The replacement must be agreed with the doctor, since Pulmicort has been proven effective and safe to use. It is usually not recommended to choose another drug in the treatment of bronchial asthma and chronic obstructive diseases of the bronchi and lungs, and replacement can be especially dangerous when relieving an attack of false croup in a child.
It is possible to use cheaper medications for allergic rhinitis, complex treatment of sinusitis, as well as when prescribing hormones for inhalation in a short course. If you need to replace the Pulmicort Turbuhaler aerosol can, then choose between Benacort, which is similar in cost, or Budesonide Easyhaler, which has a higher price. In case of intolerance to the active substance, Flixotide, Alvesco, Beclazon eco are prescribed.
pharmachologic effect
Manufacturer: ASTRAZENECA AB (Sweden)
Release form: dosed suspension, powder for inhalation
Active ingredient: budesonide
Analogues: Berodual, Symbicort, Pulmicort
Pulmicort is part of the group of glucocorticoid agents for topical use that have anti-inflammatory and antiallergic effects.
The drug reduces the frequency of exacerbations of respiratory diseases, swelling of the bronchial mucosa, and the production of bronchial secretions.
Budesonide, which is part of Pulmicort, reduces hyperreactivity of the respiratory tract, which leads to relief of pathological symptoms and improvement of the patient's condition.
Side effects
For the respiratory system: dry mouth, cough, irritation of the mucous membranes of the respiratory tract, carious lesions of the oropharynx. Considering the possibility of carious lesions of the oropharynx, those taking the drug should carefully monitor oral hygiene.
For the endocrine system: hypofunction of the adrenal cortex, as well as symptoms of systemic effects of glucocorticosteroids.
For the central nervous system: excitability, inappropriate behavior, nervousness, depression, fog.
Allergic reactions: contact dermatitis , rash, angioedema , urticaria . If you use a nebulizer with a mask, facial skin irritation may occur.
Pulmicort - instructions for use
According to the instructions for use of Pulmicort, the dosage of the medication is calculated individually, taking into account the severity of the bronchopulmonary process. A single administration of the drug is possible if the daily dose does not exceed 1 mg. At a higher recommended dosage, the dose is divided into 2 doses. The inhalation dose of the drug is:
- Adults and elderly. 1–2 mg per day is the initial amount of the drug. As maintenance therapy, it can range from 0.5 to 4 mg with further increases as indicated.
- For children. The initial dose for children aged six months and older ranges from 0.25 to 0.5 mg per day with a possible increase to 1 mg according to indications. For maintenance treatment, it ranges from 0.25 to 2 mg.
Inhalations are carried out using a nebulizer, into which a Pulmicort suspension diluted with a 0.9% sodium chloride solution is placed. To prevent the development of candidiasis of the oropharyngeal mucosa or skin, after the procedure it is necessary to rinse the oral cavity with water or wash if a mask from the device was used.
special instructions
To minimize the risk of oropharyngeal fungal infection, the patient should be instructed to rinse the mouth with water after each inhalation of this medication.
The drugs Pulmicort and Pulmicort Turbuhaler should not be taken together with Itraconazole , Ketoconazole , as well as other substances that retain CYP 3A4 in the body. If these substances were nevertheless prescribed to the patient simultaneously with budesonide (the main active ingredient of the drug), then the time between doses of these drugs should be maximized.
Due to the risks that pituitary-adrenal function may be weakened, special attention is required to those patients who are transferred to Pulmicort and Pulmicort Turbuhaler from oral glucocorticosteroids. In addition, special attention should be paid to those patients who have received the maximum recommended doses of glucocorticosteroids for a long time. Such patients may experience symptoms and signs of adrenal insufficiency . Also, in cases of surgery or stress, additional therapy with systemic glucocorticosteroids is recommended.
Particular attention should be paid to those patients who are transferred from systemic to inhaled glucocorticosteroids, as well as in cases where a violation of the pituitary-adrenal function is expected. In these cases, it is necessary to carefully reduce the dose of systemic glucocorticosteroids, as well as monitor adrenal hormonal function.
If a patient switches from taking oral corticosteroids to Pulmicort or Pulmicort Turbuhaler, he may experience symptoms such as joint pain or muscle pain. In this case, it may be necessary to temporarily increase the dose of oral corticosteroids. In some cases, nausea and vomiting, headache, and fatigue may also occur, which indicates a systemic deficiency of glucocorticosteroids.
If oral corticosteroids have been replaced by inhaled ones, then sometimes a concomitant allergy ( eczema or rhinitis ) appears, which was previously treated with systemic medications.
In addition, patients should be instructed that if the effectiveness of therapy with short-acting bronchodilators is reduced, they should consult a doctor, since an unauthorized increase in the frequency of use of the drug may delay the prescription of an adequate dosage for treatment. If there is a sudden deterioration in the condition, then the possibility of treatment with oral corticosteroids should be considered.
Analogues of Pulmicort
The pharmaceutical industry produces a wide range of Pulmicort analogues for the nebulizer, used for inhalation with similar treatment results. They are sold by the pharmacy chain in the form of:
- synonyms;
- generics;
- combined means.
A wide variety of Pulmicort substitutes allows the doctor to more carefully select a drug that corresponds to the individual characteristics of the course of respiratory diseases.
List of Pulmicort analogues for inhalation with prices
Analogue | Cost in rubles | Manufacturer country |
Pulmicort | 450-1200 | Sweden |
Berodual | 250-500 | Italy |
Symbicort | 1100-2450 | Sweden |
Budesonide | 800-1100 | Finland |
Lazolvan | 390-450 | Russia |
Pulmibud | 680-800 | Russia |
Budenit Steri-Neb | 750-1280 | Great Britain |
Dexamethasone | 120-170 | Russia |
Fluimucil | 230-250 | Switzerland |
Salbutamol | 130-250 | Russia |
Beclomethasone | 290-400 | Finland |
From the list of analogues of Pulmicort for inhalation, we can highlight domestic products that have a budget cost and a good therapeutic effect.
Price, where to buy
The price of Pulmicort for inhalation varies depending on the calculated doses. 20 pieces of 500 mcg/ml can be purchased from 1150 to 1250 rubles. Nebulas for 20 pieces of 250 mcg/ml cost from 800 to 950 rubles.
The price for Pulmicort Turbuhaler in different pharmacies is set from 700 to 800 rubles. for the 100 mcg per dose option. The option with 200 mcg per dose costs about 450 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Pulmicort Susp.
for in. 0.25 mg/ml cont. 2ml 20 pcs AstraZeneca AB 630 RUR order - Pulmicort Susp. for in. 0.5 mg/ml cont. 2ml 20 pcs AstraZeneca AB
RUB 877 order
Pharmacy Dialogue
- Pulmicort sachets 0.5 mg/ml 2 ml No. 20Astra Zenesa
906 rub. order
- Pulmicort sachets 0.25 mg/ml 2 ml No. 20Astra Zenesa
RUB 613 order
- Pulmicort Turbuhaler (portion d/ing. 200 mcg/dose 100 doses) Astra Zenesa
412 rub. order
- Pulmicort Turbuhaler (portion d/ing. 100 mcg/dose 200 doses) Astra Zenesa
RUR 585 order
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Pharmacy24
- Pulmicort Turbuhaler powder for inhalation 200 mcg/dose 100 doses Astra Zeneca AB, Sweden
276 UAH.order - Pulmicort Turbuhaler powder for inhalation 100 mcg/dose 200 doses Astra Zeneca AB, Sweden
269 UAH. order
- Pulmicort nebula 0.5 mg/ml 2 ml N20 suspension for inhaler Astra Zeneca AB, Sweden
759 UAH. order
- Pulmicort nebula 0.25 mg/ml 2 ml No. 20 suspension for inhaler Astra Zeneca AB, Sweden
526 UAH order
PaniPharmacy
- aerosol Pulmicort turbuhaler 100 mg/dose 200 doses Ukraine, AstraZeneca
277 UAH order
- Pulmicort liquid Pulmicort suspension. d/spray 0.25 mg/ml cont. 2ml No. 20 (4x5) Sweden, AstraZeneca
548 UAH order
- Pulmicort liquid Pulmicort suspension for spraying 0.5 mg/ml container 2 ml No. 20 (4x5) Sweden, AstraZeneca
812 UAH order
- aerosol Pulmicort turbuhaler 200 mg/dose 100 doses Ukraine, AstraZeneca
273 UAH order
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Pulmicort or Berodual - which is better for inhalation
Manufacturer: INSTITUTE DE ANGELI SRL (Italy)
Release form: metered aerosol, solution for inhalation
Active ingredient: ipatropium bromide, fenoterol
Both drugs have equivalent indications, but act differently and are in different groups. Pulmicort eliminates the inflammatory process in the respiratory tract, and it will be best for laryngitis. Its analog expands the lumen of the bronchi, eliminating spasm and difficulty breathing. Berodual has a fast action, it will be more effective for bronchitis.
For children older than six months, Pulmicort will be the best, as it effectively eliminates inflammation and cough during pneumonia. For babies under 6 months of age, only Berodual is prescribed, since it is safer and is a combined drug, the combined action of the active substances of which potentiates the therapeutic effect.
Inhalation of an analogue for coronavirus gives the best result in severe cases of the process, as it reduces the clinical manifestations of respiratory failure.
Pulmicort or Symbicort - which is better and stronger
Manufacturer: ASTRAZENECA AB (Sweden)
Release form: dosed powder for inhalation
Active ingredients: budesonide, formoterol
Both medications contain the same active substance. But this analogue of Pulmicort for inhalation by adults is supplemented with one more active ingredient. This combination of the drug makes it stronger.
Due to the combination of active substances, Symbicort turbuhaler powder will be the best, since this product is convenient to use, relieves severe attacks of bronchial asthma much faster and more effectively.
During pregnancy and lactation
When pregnant women take the substance budesonide, no increased risk of developing abnormalities in the fetus has been found. However, these risks should not be completely excluded, therefore, when taking the drug during pregnancy , you should use the minimum effective dosage of the drug to avoid worsening bronchial asthma .
Animal studies have shown results of the development of fetal abnormalities when taking corticosteroids, but these data cannot be transferred to people who receive recommended doses of glucocorticosteroids.
The following information will be useful for nursing mothers: there is no evidence that budesonide can pass into breast milk. But still, when prescribing this drug, you need to take into account the potential risks for the child, comparing them with the expected benefits.
Pulmicort or Budesonide - which is better for inhalation
Manufacturer: ORION PHARMA (Finland)
Release form: powder for inhalation
Active ingredient: budesonide
Pulmicort and its analogue Budesonide have the same active substance, are in the same pharmacological group and have the same mechanism of action. The difference between the drugs lies in dosages, release forms, and indications.
Budesonide native will be preferable for the treatment of rhinitis or the prevention of the formation of polyposis. When treating bronchial asthma or lactose intolerance, it is better to breathe with Pulmicort, which quickly relieves bronchospasm.
Pulmicort for inhalation and its analogues are cheap
Pulmicort and its cheaper inhalation analogs (Budenit Steri-Nab and Budesonide Native) have similar characteristics.
Mechanism of action
Hormonal drugs with budesonide have medicinal properties:
- relieve inflammation of the bronchial mucosa;
- reduce shortness of breath, cough, frequency and severity of attacks in bronchial asthma;
- facilitate the course of obstructive (with bronchospasm) disease of the bronchi and lungs, since the respiratory tract reacts less to inhalation of an allergen, cold air or physical activity;
- have an anti-edematous effect;
- inhibit the production of sputum and mucus, stimulate their excretion.
The drugs are well tolerated and do not retain fluid in the body. The active substance is processed by the liver, and its metabolic products circulating in the blood have only 1% of hormonal activity. Therefore, Pulmicort and analogues act predominantly locally. The maximum therapeutic effect is observed after 10 days of use.
A very important feature of medications with hormones is their ability to prevent severe attacks of bronchial asthma, but they cannot relieve bronchospasm itself. Therefore, patients may be recommended to inhale drugs with a bronchodilator effect (for example, Berodual or Ventolin). They are used 15-20 minutes before inhalation of Pulmicort and analogues.
Indications for use
Pulmicort and analogues are prescribed for conditions that require the use of hormones:
- hormone-dependent bronchial asthma;
- chronic obstructive pulmonary disease;
- obstructive bronchitis with severe course;
- acute attack of suffocation with stenosing laryngitis (false croup) against the background of a viral infection.
Contraindications
The use of Pulmicort and its analogues is prohibited for children under 6 years of age and for those who are intolerant to budesonide. Cautious use is allowed (under medical supervision and with regular tests, diagnostic studies) when:
- active tuberculosis infection;
- fungal, viral or bacterial diseases of the respiratory system;
- liver failure, liver cirrhosis, viral hepatitis.
The drug is not contraindicated for pregnant and lactating women, but it is important to use minimal doses and avoid long-term treatment.
Adverse reactions
Pulmicort and analogues do not cause complications in 90% of patients when used at the recommended dose. About 10% of patients may experience:
- irritation of mucous membranes,
- sore throat,
- coughing,
- dry mouth,
- hoarseness of voice,
- headache,
- rashes on the body,
- increased excitability,
- insomnia,
- depressive disorders.
With long-term use of large doses, in some cases, suppression of the adrenal glands is possible.
Pulmicort or Lazolvan for inhalation - which is better?
Manufacturer: SANOFI JSC (Russia)
Release form: solution for inhalation
Active ingredient: ambroxol
Lazolvan and Pulmicort are used to treat diseases of the respiratory system, but, having different active components, they act by different mechanisms.
This analogue of Pulmicort for children and adults will be the best for inflammatory processes accompanied by cough. This safe and powerful mucolytic agent has a wider range of indications (sore throat, pharyngitis, tracheitis).
Pulmicort is a hormonal drug, the use of which is preferable for more severe respiratory diseases.
Pulmibud or Pulmicort - which is better, what is the difference
Manufacturer: JSC AKRIKHIN (Russia)
Release form: dosed suspension for inhalation
Active ingredient: budesonide
The drugs have the same active substance, 1 pharmacological group and mechanism of action. The difference between the products lies in the release form and dosages. Pulmicort is produced in the form of an inhalation suspension and powder.
The portable inhaler Pulmicort Turbuhaler has different dosages. Its analogue is used only in the form of a suspension. According to patient reviews, Pulmicort will be the best. It is better tolerated by patients and taking the medication is more convenient using an inhaler, which allows you to breathe in small doses.
Pharmacodynamics and pharmacokinetics
Budesonide, which enters the body by inhalation, is quickly absorbed. Approximately 25-30% of the drug dose reaches the lungs. After half an hour, the highest concentration of the drug in the blood plasma . The systemic bioavailability of Pulmicort is approximately 38% of the dose taken.
The binding of the drug to plasma proteins is at the level of 90%. The distribution of budesonide by volume is about 3 liters per kilogram. Upon completion of absorption, intense biotransformation of budesonide occurs in the liver, resulting in the formation of metabolites that have low glucocorticosteroid activity.
The substance budesonide INN is mainly metabolized with the participation of the enzyme CYP 3A4. Then, in conjugated form or simply with urine, unchanged metabolites are excreted from the body.
The pharmacokinetics of budesonide in patients with impaired renal function and in children is unknown. And in patients with liver disease, the time budesonide remains in the body may increase.
Pulmicort or Budenit Steri-Neb
Manufacturer: NORTON HEALTHCARE LTD (Great Britain)
Release form: dosed suspension for inhalation
Active ingredient: budesonide
These medications are similar in active substances and effects on the body. They differ from each other in the composition of auxiliary ingredients. When comparing them, the best would be Pulmicort, which has greater safety, fewer contraindications, and is not addictive.
The bioavailability of the analogue is more than 2 times lower, so the therapeutic effect of Budenit Steri-Neb inhalations will be lower.
How to replace Pulmicort
If there is a need to replace Pulmicort in case of intolerance to budesonide, then they are guided by the disease and the characteristics of its course.
Pulmicort turbuhaler analogues for asthma
Instead of Pulmicort in the form of turbuhaler, a drug with equal potency of Alvesco can be prescribed. This is a relatively new drug with the active ingredient ciclesonide. Its difference is even greater safety when used for inhalation.
This is explained by the fact that a hormone already processed in the lungs, which has a strong anti-inflammatory local effect, penetrates into the bloodstream. Only a small part of the sprayed drug is absorbed into the blood. The advantages also include the possibility of only one use per day. Alvesco is used for basic therapy (the main method of treatment) of bronchial asthma, since it:
- reduces the reaction of the bronchi to factors that provoke spasms;
- relieves the severity of attacks, they occur less frequently;
- reduces the need for bronchodilators and hormones in tablets for internal use.
Pulmicort can be replaced by a doctor and with Flixotide or Beclazone eco.
Pulmicort substitute for inhalation for false croup
Instead of Pulmicort for false croup, Ventolin or Berodual may be recommended for inhalation. These substitutes do not act on the inflammatory process, but relieve spasm of the respiratory tract. The disease occurs mainly in young children with the development of severe swelling of the larynx due to a viral infection. Therefore, it is necessary to supplement treatment with antiviral agents. Can be assigned:
- during an attack: Ventolin 2.5 ml undiluted or Berodual 15 drops per 3 ml saline;
- Derinat 2 ml with 2 ml saline 2 times a day for 1 week;
- mineral water “Borjomi” 4 ml 2 times a day for 1 week.
Pulmicort can be replaced with direct analogues in composition - Budesonide native or Budenit steri-neb when sprayed through a nebulizer. Instead of an aerosol in a can, if the drug is intolerant, Flixotide, Beclazon eco, Alvesco are prescribed.
Pulmicort or Dexamethasone for inhalation
Manufacturer: JSC AKRIKHIN (Russia)
Release form: tablets, eye drops, ampoules for injections and inhalations
Active ingredient: dexamethasone
Both drugs belong to the same group, but act differently. Dexamethasone is a cheap analogue of Pulmicort for inhalation; it has a wide range of indications, a variety of forms, and low cost. Despite these advantages, the best would be Pulmicort, which has minimal contraindications and side effects. When the drug is inhaled, its effectiveness exceeds that of Dexamethasone.
Beclomethasone
Manufacturer: ORION PHARMA (Finland)
Release form: aerosol for inhalation
Active ingredient: beclomethasone
Beclomethasone belongs to the group of glucocorticosteroid drugs that have anti-inflammatory, anti-edematous, anti-allergic and anti-asthmatic effects. The drug relaxes the smooth muscles of the bronchi, thickens the basement membrane of the bronchial epithelium and increases its sensitivity to adrenergic agonists.
What else can replace Pulmicort for inhalation for children and adults, what effective means? You can supplement the list of medications with the following medications:
- Eufillin;
- Ventolin;
- Atrovent;
- Ambroxol;
- Prednisolone;
- Seretide;
- Flixotide;
- Ambrobene;
- Beclazon;
- Ventolin;
- Klenil.
Among these medications, there are cheaper analogs of Pulmicort, which are used in the form of an inhalation solution using a nebulizer.
A correctly selected analogue for the treatment of respiratory tract diseases will reduce the clinical manifestations of the disease, prevent its progression and avoid serious complications.
Answers on questions
Is it possible to take Pulmicort for coronavirus or not?
The drug can be used for severe forms of coronavirus.
Is Pulmicort for inhalation a hormonal drug or not?
Yes, this is a hormonal medicine.
What to breathe first: Pulmicort or Berodual?
First of all, Berodual, and then Pulmicor.
Is Pulmicort for inhalation an antibiotic or not?
No, the medicine is not an antibiotic.
Should Pulmicort be diluted with saline solution or not?
The product must be diluted with saline solution in equal proportions.
Is Pulmicort available with a prescription or not?
The drug is available with a doctor's prescription.