Bifiform Baby oil solution 7 ml x1

Pharmacodynamics and pharmacokinetics

The manufacturer reports that the effect of this drug is due to its constituent components, which maintain and control the physiological balance of intestinal microflora . They colonize the small and large intestines. By producing acetic and lactic acids, active bacteria inhibit the growth and reproduction of pathogenic microorganisms.

The drug improves the functioning of the gastrointestinal tract, increases the body's nonspecific resistance and normalizes intestinal microbiocenosis.

Bifiform

Bifiform ®

(lat.
Bifiform
® ) is a medicine that normalizes intestinal microflora, a probiotic.
Available in the form of enteric-coated capsules. Active components:

• Bifidobacterium longum ,
  one capsule contains at least 10,000,000 bacterial cells
• Enterococcus faecium ,
  one capsule contains at least 10,000,000 bacterial cells

Excipients:
anhydrous dextrose (glucose), lactulose, lactic acid starter, gum, magnesium stearate.
Capsule shell substances:
copolymer of methacrylic acid and methyl methacrylate (MAA-MAS), copolymer of methacrylic acid and ethacrylate (MAA-EAC 30%), talc, macrogol 6000, titanium dioxide, soybean oil, magnesium stearate, acetylated glycerides.

Bifiform is intended for the treatment and prevention of dysbacteriosis of various etiologies. The lactic acid bacteria included in the drug maintain and regulate the physiological balance of intestinal microflora. The acid-resistant capsule protects the bacteria contained in the drug from destruction under the influence of gastric acid. When it enters the intestines, where the acidity of the environment is 6.0 - 6.8 pH, the capsule dissolves. Bacteria actively colonize the small and large intestines. They produce acetic and lactic acids, thereby inhibiting the growth and reproduction of pathogenic microbes. Bifidobacteria and non-toxigenic lactic acid enterococci Enterococcus faecium

also participate in the synthesis and absorption of vitamins, carry out the enzymatic breakdown of proteins, fats and complex carbohydrates (including lactase deficiency in children). Bifiform contributes to a significant reduction in opportunistic microflora (staphylococcus, Proteus, hemolytic Escherichia coli, Klebsiella, etc.).

Bifidobacterium longum

- an anaerobic gram-positive bacterium that colonizes predominantly the large intestine, being its main parietal and luminal microflora.
In healthy newborns who are breastfed, Bifidobacterium longum
colonizes the intestines from 5 to 20 days after birth.
In young children, Bifidobacterium longum
makes up the majority of all intestinal microorganisms. The strain used in bifiform is ATCC 15707.

Enterococcus faecium

(old name
Streptococcus faecium
) is an aerobic gram-positive bacterium, lactic acid enterococcus, which colonizes primarily the small intestine. Bifiform uses a specially selected non-toxigenic strain of Enterococcus faecium SF68, which is characterized by a high level of antibiotic resistance and non-pathogenicity.

In the genome of the Enterococcus faecium

SF68 lacks the virulence genes known for pathogenic clinical isolates of enterococci: gelE (
gelatinize
), sprE (
serine protease
), esp (
extracellular surface protein
), fsrB (
virulence factor regulator
), asa1 (
aggregation substance
).
Enterococcus faecium
SF68 is sensitive to vancomycin, ampicillin, piperacillin, chloramphenicol, erythromycin, imipenem, ciprofloxacin and fusidic acid and resistant to methicillin, cefuroxine, aztreonam, mipramine, tobramycin, streptomycin (Bondarenko V.M. Multicomponent probiotics : therapeutic effect for intestinal dysbiosis and mechanism of action).

Taking B. longum

and
E. faecium
results in transient colonization of the intestine (increase in abundance) by these bacteria for a period of approximately 7 days. These bacteria, despite numerous beneficial effects, as well as all other probiotic strains included in drugs and dietary supplements, are not equivalent to their own indigenous microflora and are not able to multiply in the intestines. One reason for this may be bioincompatibility with resident human bacteria. Even the most effective probiotics only act during the course of treatment and are found in feces no longer than one to two weeks after the end of treatment.

Indications for use:

• normalization of intestinal microflora
• prevention and treatment of gastrointestinal disorders
• maintaining immunity in children over 2 years of age and adults

Helicobacter pylori
eradication therapy , due to the possibility of side effects associated with the development of dysbiotic changes in the intestine, the inclusion of probiotics in the treatment regimen is recommended. The drugs of choice are complex probiotic agents, such as Bifiform and Linex (Khavkin A.I., Zhikhareva N.S., Rachkova N.S.).

Professional medical publications,

concerning the use of bifiform in the treatment of the gastrointestinal tract:

• Khavkin A.I., Zhikhareva N.S., Rachkova N.S. Modern principles of therapy for peptic ulcer // Attending physician. – 2005. – No. 2. – p. 30–33.
• Fadeeva N.A. The role of small intestinal microflora in the development of secondary lactase deficiency. Abstract of dissertation. PhD, 01/14/28 – gastroenterology. MKSC, Moscow, 2015.

On the website in the literature catalog there is a section “Probiotics, prebiotics, synbiotics, symbiotics”, containing articles on the treatment of diseases of the gastrointestinal tract with probiotics, prebiotics and synbiotics.
Doses.

Inside.
Adults and children over 2 years old, 2 - 3 capsules per day. There are no recommendations for taking bifiform before, during or after meals. If necessary, the daily dose can be increased to 4 capsules. The antidiarrheal effect is achieved, most often, on the first day of using bifiform. For acute diarrhea, the course of treatment can be 2 to 3 days. In other cases, the course of treatment is 10-21 days. Bifiform is an over-the-counter medicine
.

According to the pharmacological index, Bifiform belongs to the group “Medicines that normalize intestinal microflora”. According to ATC, it belongs to the group “Antidiarrheal microorganisms”, code A07FA.

Manufacturer:

Ferrosan A/S (Ferrosan), Denmark.

Instructions from the company: enteric capsules. Bifiform has contraindications, side effects and application features; consultation with a specialist is necessary.

Bifiform dietary supplements

Ferrosan A/S produces several dietary supplements (which are not drugs) with similar names and also intended to combat intestinal dysbiosis: Bifiform® Baby
,
Bifiform® Baby
and
Bifiform® Complex
.

Bifiform Baby

Designed for children from the first days of life.
Contains (in a daily dose of 0.5 g) the following active ingredients:

• Bifidobacteria (strain Bifidobacterium animalis lactis
  BB-12): at least 1,000,000,000 bacterial cells.
• Streptococcus thermophilus (strain Streptococcus thermophilus
  TH-4): at least 100,000,000 bacterial cells.

Excipients:
maltodextrin, silicon dioxide, medium chain triglycerides obtained from coconut and palm kernel oil.

Bifiform Baby

is available in two forms: chewable tablets for children aged 2 years and older and powder for children aged 1 year and older with an orange-raspberry flavor.
Contains in one tablet or one sachet of powder (sachet) the following active ingredients:

• Lactobacilli (strain Lactobacillus rhamnosus
  ATCC 53103, trade name
  LGG
  ) - at least 1,000,000,000 bacterial cells (3.33 mg).
• Bifidobacteria (strain Bifidobacterium animalis lactis
  BB-12) - at least 1,000,000,000 bacterial cells (3.33 mg).
• Vitamin B1 - 0.4 mg.
• Vitamin B6 - 0.5 mg.

Excipients:
isomaltose, xylitol, fructooligosaccharide, microcrystalline cellulose, orange flavor, raspberry flavor, silicon dioxide, magnesium stearate, methylcellulose, stearic acid.

Dosage and administration recommended by the manufacturer:

Children from 1 year old: 1 - 2 powders 2 - 3 times a day. Children from 2 years old: 1 - 2 tablets 2 - 3 times a day. Take regardless of meals, for 5 days or more.

Bifiform Complex

- tablets with inulin. Daily dose (2 tablets) contains:

• Bifidobacteria (strain Bifidobacterium animalis lactis
  BB-12)—at least 1,000,000,000 bacterial cells.
• Lactobacilli (strain Lactobacillus rhamnosus
  ATCC 53103 LGG) - at least 1,000,000,000 bacterial cells.
• Lactobacilli (strain Lactobacillus acidophilus
  LA-5) - at least 1,000,000,000 bacterial cells.
• Inulin - at least 720 mg.

Excipients:
isomaltose, microcrystalline cellulose, mono- and diglycerides of fatty acids, croscarmellose sodium, silicon dioxide.

Dose and order of administration recommended by the manufacturer: adults and children over 11 years old - 2 tablets per day with meals.

On the website in the literature catalog there is a section “Dysbacteriosis”, containing articles addressing the problems of dysbiosis of the gastrointestinal tract.

Back to section

Instructions for use Bifiform (Method and dosage)

For those who have been prescribed Bifiform capsules, the instructions for use indicate that adults and children over 2 years old need to take the medicine 2-3 capsules per day. If necessary, the daily dosage is increased to 4 capsules.

Instructions for use of Bifiform also indicate that in the treatment of gastrointestinal disorders, an antidiarrheal effect can be observed already in the first days of treatment. For acute diarrhea, the course is designed for 2-3 days. For those who are interested in how to take Bifiform for adults, if there are other indications for use, it is better to consult with specialists. The doctor usually prescribes a course of treatment from 10 to 21 days.

In addition, this remedy can be prescribed in combination with others, for example, capsules and suppositories with Indomethacin .

Also on forums they often ask how to take it: before or after meals. Experts report that you can take capsules regardless of meals.

Doctors are also interested in how to take it with antibiotics . Experts answer this question unequivocally - it is better to avoid such a combination altogether. Bifidobacteria will be destroyed, so the use of the drug must be started after antibiotic treatment. It is better to consult a doctor about how and when to drink.

Component Properties

Bifiform®Baby food supplement is a combination of beneficial probiotic bacteria developed for children from the first days of life and adults.

Bifiform® Baby contains: Bifidobacterium BB-12™, Streptococcus thermophilus TH-4.

Bifidobacterium animalis, subspecies lactis BB-12 and Streptococcus thermophilus TH-4, which are part of Bifiform® Baby, are traditionally used in the food industry and are considered safe, which is confirmed by the long history of their successful use in the production of dairy products and baby food.

Probiotic suspension Bifiform® Baby helps restore the balance of intestinal microflora. The release form in the form of a suspension is convenient and easy to dose and facilitates use in children from the first days of life and adults.

The use of Bifiform® Baby promotes the formation and restoration of intestinal microflora in children from the first days of life. The use of probiotic complexes is primarily recommended for children who are at risk for an imbalance in the intestinal microflora (features of pregnancy and childbirth in the mother), as well as after suffering from colds, treatment with antibiotics and some other medications. Restoring the balance of intestinal microflora allows you to eliminate such manifestations of dysbiosis as gastrointestinal upset, bloating and discomfort.

Bifiform's analogs

Level 4 ATC code matches:
Biobacton

Lactobacterin

Bactisubtil

Sporobacterin

Hilak forte

Subalin

Linex Forte

Linex

Florin Forte

Biosporin

Bifiliz

Probifor

Colibacterin

Bifidumbacterin Forte

Bifidumbacterin

Lacidophilus

Bificol

Acipol

Enterol

You can find the following analogues of Bifiform:

• Acylact
• Biosporin
• Bifidumbacterin
• Lactobacterin
• Acipol
• Bactisubtil
• Bifidumbacterin Forte
• Linex
• Probifor
• Flonivin BS
• Enterol
• Linex Gastro
• Biobakton
• Bifilong
• Bifinorm
• Colibacterin
• Sporobacterin

Similar drugs have their own nuances of use, which you should also be aware of. Despite the fact that the price of Bifiform analogues is in many cases lower, it is better not to take them without a doctor’s prescription.

Which is better: Bifiform or Acipol?

Often this drug is prescribed together with Acipol . The first remedy does not have such a strong antimicrobial effect, but it can be used by people who are lactose intolerant. So the question of which of these drugs is better must be decided individually.

Which is better: Bifiform or Bifidumbacterin?

Bifidumbacterin is a Russian drug. Its cost is lower than that of the European one. However, experts still recommend the first drug. They say it is more effective.

Normobact or Bifiform - which is better?

Both remedies are considered very effective. In terms of action, there is no significant difference between them. Normobact in most cases has a lower cost, but it has its own nuances of use.

Difference between Bifiform and Bifiform Complex

Unlike the drug in question, which is a drug, Bifiform Complex is registered in the Russian Federation as a dietary supplement. The difference between the drugs is already visible in the composition. The latter remedy contains Bifidobacterium BB-12, Lactobacillus rhamnosus GG, Lactobacillus acidophilus LA-5 as active substances. Thus, it has three strains of bacteria at once.

The medicine is sold in capsules, the protective shell of which prevents the death of bacteria when they enter the aggressive environment of the stomach. Bifiform Complex, in turn, is available in tablets, which immediately dissolve when they enter the body, so that the bacteria die in the stomach. Thus, this dietary supplement is not very effective. The manufacturer, however, continues to produce it. Since the names of both drugs are similar, this can be somewhat confusing for buyers.

Composition and release form

in 6.9 ml bottles (complete with dosing pipette), sealed with a cap containing 160 mg of powder.

Bifiform during pregnancy

It is a very common belief that most medications are contraindicated during pregnancy . However, there are also useful medications that can help women expecting a child regulate metabolic processes in the body and improve intestinal microflora. The drug in question belongs to them.

Instructions for use during pregnancy indicate that there are no obstacles to the use of these capsules. They belong to probiotics , which means that this product is able to well regulate intestinal microflora. Bifiform during pregnancy is in many cases prescribed by specialists. Its use does not affect the development of the fetus. Thus, this product fully copes with its functions and does not harm the child.

Reviews about Bifiform

Reviews about Bifiform on forums are mostly positive. Those who have already tried this product note that its effect is noticeable from the first days of use. The positive effect becomes obvious almost from one capsule.

In addition, reviews of Bifiform report that it helps with acne. After all, they can often be caused precisely by a violation of the microflora in the intestines.

Reviews from doctors also leave no doubt about the effectiveness of this product. They often prescribe it to their patients, especially children, who really like its taste.

Bifiform price, where to buy

The price of Bifiform in capsules of 30 pieces per package is about 500 rubles. The cost, however, may vary depending on the region.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Bifiform probiotic without lactose for normalizing intestinal function in adults and children from 2 years old 30 capsules Pfizer Consumer Manufacturing Italy S.R.L.
  RUR 574 order
• Bifiform Kids flavor orange-raspberry tab. chewing 20pcs Ferrosan

  RUR 615 order

Pharmacy Dialogue

• Bifiform capsules No. 30Pfizer

  RUR 564 order

• Bifiform Kids chewable tablets No. 20 (orange-raspberry) Ferrosan

  660 rub. order

• Bifiform capsules No. 40Pfizer

  RUR 695 order

show more

PaniPharmacy

• Bifiform plus capsule Bifiform Plus for regulation of intestinal microflora capsules No. 20 Austria, Ferrosan
  175 UAH.order

show more