pharmachologic effect
The product normalizes the functions of the digestive system. Liquid Intesti-bacteriophage has a specific antibacterial effect against a number of bacterial strains. In the process of exposure, Intesti-bacteriophage lyses specifically these bacteria, attaching to their membranes. Then it penetrates inside the cell, after which it multiplies using the energy resource of the bacterial cell. After the cell dies, mature phage particles are released, which can infect other cells of the strain.
The drug is strictly specific to homologous bacteria, so normal microflora is not suppressed and there is no harmful effect on the cells of the body. Intesti-bacteriophage stimulates immunity , effectively improves the condition of purulent-septic diseases that are accompanied by immunosuppressive conditions. Before starting treatment, the phage sensitivity of the pathogen should be determined.
Instructions for use Intesti-bacteriophage (Method and dosage)
The instructions for Intesti-bacteriophage stipulate that the medicine can be used orally and rectally. Before using the solution, you need to shake the container and examine the contents. If particles are found in it, the transparency or color changes, in this case the drug cannot be used.
Instructions for use of Intesti-bacteriophage stipulate that when using the drug, you must first wash your hands and treat the bottle cap with an antiseptic. You can't leave it open. The required amount of solution must be drawn up with a sterile syringe. The exact period of time treatment should last is determined by the doctor in each individual case.
If children develop side effects when treated with Intesti-bacteriophage, the product can be diluted with water. If severe vomiting is observed, the drug is administered rectally to the person.
For children under 6 months, a single dose is 5 ml (orally) and 10 ml (rectally). Children 6-12 months old are prescribed a single dose of 10-15 ml (orally) and 20 ml (rectally). For children 1-3 years old, a single dose of 15-20 ml (orally) and 20-30 ml (rectally) is indicated. Children 3-8 years old should receive a dose of 20-30 ml (oral administration) and 30-40 ml (rectal administration). Patients over 8 years of age and adults should take 30-40 ml orally and 50-60 ml rectally.
The drug is prescribed orally 4 times a day, it should be taken one hour before meals.
If the solution is prescribed for prophylactic purposes, one single dose per day is indicated. Treatment is prescribed at the first symptoms, as a rule, it is carried out for 7-10 days.
Bacteriophage intesti liquid
INTESTI-BACTERIOPHAGE (INTESTI-BACTERIOPHAGE) Release form, composition and packaging Solution for oral or rectal administration, a mixture of sterile filtrates of phagolysates of Shigella flexneri 1, 2, 3, 4, 6 serovars, Shigella sonnei, Salmonella paratyphi A, Salmonella paratyphi B, Salmonella typhimurium, Salmonella infantis, Salmonella choleraesuis, Salmonella oranienburg, Salmonella enteritidis, enteropathogenic Escherichia coli of various serogroups, the most significant in the etiology of enteric diseases, Proteus vulgaris, Proteus mirabilis, Enterococcus, Staphylococcus, Pseudomonas aeruginosa.
Excipients: quinosol 0.0001 g/ml
20 ml - bottles (4) - cardboard packs. 20 ml - bottles (10) - cardboard packs. 100 ml - bottles (1) - cardboard packs.
Clinical and pharmacological group: Immunobiological drug - bacteriophage Registration No.: • solution for oral or rectal use: 20 ml vial. 4 or 10 or 100 ml fl. 1 - LS-001999, 12/12/12. Validity period of reg. beat is not limited.
The description of the drug INESTI-BACTERIOPHAGE is based on the officially approved instructions for use of the drug INESTI-BACTERIOPHAGE and was made in 2013. Pharmacological action The drug causes specific lysis of bacteria Shigella flexneri 1, 2, 3, 4, 6 serovars, Shigella sonnei, Salmonella paratyphi A, Salmonella paratyphi B, Salmonella typhymurium, Salmonella infantis, Salmonella choleraesuis, Salmonella oranienburg, Salmonella enteritidis, Escherichia coli, Proteus vulgaris, Proteus mirabilis, Enterococcus, Staphylococcus, Pseudomonas aeruginosa.
Indications for use of the drug INESTI-BACTERIOPHAGE
Treatment and prevention of diseases of the gastrointestinal tract caused by dysentery bacteria, salmonella, Escherichia coli, Proteus, enterococci, staphylococci, pseudomonas aeruginosis or their combination: - bacterial dysentery, - salmonellosis, - dyspepsia, - dysbacteriosis, - enterocolitis, colitis.
An important condition for effective phage therapy is the preliminary determination of the phage sensitivity of the pathogen.
Dosage regimen The drug is intended for oral and rectal administration. For treatment, the drug is taken orally 4 times a day 0.5-1 hour before meals from the first day of the disease for 7-10 days.
For children in the first months of life, in the first two days of taking the drug, the drug is diluted with boiled water twice; in the absence of adverse reactions (regurgitation, skin rashes), the bacteriophage can be used undiluted in the future. The drug is administered orally 3 times a day 30 minutes before feeding. In cases of uncontrollable vomiting, the drug is used in the form of high enemas (through a gas tube or catheter) daily. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible. The course of treatment is 7-10 days.
Recommended dosage of the drug
Age Dose per 1 dose (ml) orally rectally 0-6 months. 5 10 6-12 months 10-15 20 from 1 year to 3 years 15-20 20-30 from 3 to 8 years 20-30 30-40 from 8 years and older 30-40 50-60
In the absence of colitic syndrome, it is recommended to replace one oral dose with a single rectal administration of a single age-specific dose of the drug in the form of an enema after bowel movement. For preventive purposes, the optimal regimen of use is daily administration of a single age-specific dose. The duration of taking the drug is determined by the conditions of the epidemiological situation.
Side effects In children of the first months of life, regurgitation and skin rashes are possible in the first 2 days of taking the drug.
Contraindications to the use of the drug INESTI-BACTERIOPHAGE are hypersensitivity to the components of the drug.
Use of the drug INESTI-BACTERIOPHAGE during pregnancy and breastfeeding The use of this medication during pregnancy and breastfeeding is possible in the presence of infections caused by phage-sensitive strains of bacteria (as recommended by a doctor).
Use in children Prescribed to children in the first months of life
Special instructions In case of turbidity, do not use the drug!
Due to the content of a nutrient medium in the drug, in which bacteria from the environment can develop, causing cloudiness of the drug, it is necessary to observe the following rules when opening the bottle: - wash your hands thoroughly, - treat the cap with an alcohol-containing solution, - remove the cap without opening the stopper, - do not put cork with the inner surface on the table or other objects, - do not leave the bottle open, - store the opened bottle only in the refrigerator.
When using small doses (2-8 drops), the drug must be taken with a sterile syringe in a volume of 0.5-1 ml. The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the shelf life.
Information about the possible effect of the drug on the ability to drive vehicles and machinery. None.
Overdose Symptoms of overdose have not been established.
Drug interactions The drug can be used in combination with other drugs, including antibiotics.
Conditions for dispensing from pharmacies Dispensed without a prescription.
Storage conditions and periods Transported in accordance with SP 3.3.2.1248-03 at a temperature of 2 to 8°C. Transportation is allowed at temperatures from 8 to 25°C for no more than 1 month. The drug is stored in accordance with SP 3.3.2.1248-03 in a dry place, protected from light and out of reach of children, at a temperature of 2 to 8 ° C. Shelf life: 2 years. A drug that has expired cannot be used.
Analogues of Intesti-bacteriophage
Level 4 ATC code matches:
Cystamine
Neovasculgen
Plantain juice
Acizol
Leucovorin
Lymphomyosot
Sodium thiosulfate
Galium-Hel
Dicarbamine
Spascuprel
Methylene blue
Ammonia
Mucosa Compositum
Coenzyme Compositum
Ubiquinone Compositum
Dimephosphone
Unithiol
Naloxone
Oscillococcinum
Dantinorm Baby
Drug analogues are drugs that have a similar effect on the body. To choose them, you must always consult a doctor.
Reviews about Intesti-bacteriophage
Parents leave positive reviews about Intesti-bacteriophage after using it rectally and orally. Basically, the medicine is prescribed for dysbiosis , and with its help it is possible to restore the functioning of the gastrointestinal tract in children. According to many parents, the improvement in condition was confirmed by appropriate tests. But in some cases there was no improvement, and there was even some deterioration in the children’s health. However, in most cases the medicine worked. To get results, doctors recommend that the sensitivity of pathogens be determined before treatment.
INESTI-BACTERIOPHAGE 100ML. No. 1 R-R D/ORDER FL.
Cost in pharmacies: Biomedservice on the street. 70 let Oktyabrya, no. 14, t. 70-06-71, cell. 8-913-636-03-69 990 rub. Biomedservice on Mira Avenue, 22, tel. 60-71-89, 60-62-73, cell. 8 983-526-39-96 980 rub. Biomedservice on the street. Ivana Alekseeva, 6, tel. 243-109, cell. 8-913-632-69-45 930 rub. Biomedservice st. Dekabristov, 45., 533-573, 8-913-649-42-83, 979 rub. Biomedservice on the street. Kuibysheva, 62, tel. 56-94-88, 56-94-85, 8-913-685-12-21 925 rub. Instructions for use:
Trade name Intesti
Dosage form
Solution for oral and rectal administration
Compound
The drug is a mixture of sterile filtrates of phagolysates of Shigellaflexneri 1, 2, 3, 4, 6 serovars, Shigellasonnei, SalmonellaparatyphiA, SalmonellaparatyphiB, Salmonellatyphimurium, Salmonellainfantis, Salmonellacholeraesuis, Salmonellaoranienburg, Salmonellaenteritidis, enteropathogenic Escherichiacoli of various serogroups, the most significant in etiology of enteric diseases, Proteus vulgaris, Proteus mirabilis , Enterococcus, Staphylococcus, Pseudomonasaeruginosa. Excipients: Preservative – 8-hydroxyquinoline sulfate – 0.0001 g/ml (calculated content); or 8-hydroxyquinoline sulfate monohydrate - 0.0001 g/ml (in terms of 8-hydroxyquinoline sulfate)
Indications for use
Treatment and prevention of gastrointestinal diseases caused by dysentery bacteria, salmonella, Escherichia coli, Proteus, enterococci, staphylococci, pseudomonas aeruginosis or a combination thereof.
- bacterial dysentery;
- salmonellosis;
- dyspepsia;
- dysbacteriosis;
- enterocolitis, colitis.
An important condition for effective phage therapy is the preliminary determination of the phage sensitivity of the pathogen.
Contraindications
Hypersensitivity to the components of the drug.
Dosage regimen and method of administration
The drug is intended for oral and rectal administration. For treatment, the drug is taken orally 4 times a day 0.5 - 1 hour before meals from the first day of the disease for 7-10 days. For children in the first months of life, in the first two days of taking the drug, the drug is diluted with boiled water twice; in the absence of adverse reactions (regurgitation, skin rashes), the bacteriophage can be used undiluted in the future. The drug is administered orally 3 times a day 30 minutes before feeding. In cases of uncontrollable vomiting, the drug is used in the form of high enemas (through a gas tube or catheter) daily. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible. The course of treatment is 7 - 10 days. Recommended dosage of the drug
| Age | Dose per 1 dose (ml) | |
| orally | rectally | |
| 0 – 6 months | 5 | 10 |
| 6 – 12 months | 10-15 | 20 |
| from 1 year to 3 years | 15-20 | 20-30 |
| from 3 to 8 years | 20-30 | 30-40 |
| from 8 years and older | 30-40 | 50-60 |
In the absence of colitic syndrome, it is recommended to replace one oral dose with a single rectal administration of a single age-specific dose of the drug in the form of an enema after bowel movement. For preventive purposes, the optimal regimen of use is daily administration of a single age-specific dose. The duration of taking the drug is determined by the conditions of the epidemiological situation.
Precautions for use
If cloudy, do not use the drug! Due to the content of a nutrient medium in the drug, in which bacteria from the environment can develop, causing cloudiness of the drug, the following rules must be observed when opening the bottle:
- wash your hands thoroughly;
- treat the cap with an alcohol-containing solution;
- remove the cap without opening the stopper;
- do not place the cork with the inner surface on a table or other objects;
- do not leave the bottle open;
- Store an opened bottle only in the refrigerator.
When using small doses (2-8 drops), the drug must be taken with a sterile syringe in a volume of 0.5-1 ml. The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the shelf life.
Possible side effects
In children of the first months of life, regurgitation and skin rashes are possible in the first two days of taking the drug.
Interaction with other drugs
The drug can be used in combination with other drugs, including antibiotics.
Use during pregnancy and breastfeeding
The use of this medication during pregnancy and breastfeeding is possible in the presence of infections caused by phage-sensitive strains of bacteria (as recommended by a doctor).
Vacation conditions
Available without a prescription Shelf life
2 years
Release form Solution for oral and rectal administration in bottles of 20 or 100 ml.
4 or 10 bottles of 20 ml or 1 bottle of 100 ml with instructions for use in a cardboard pack. Manufacturer
NPO Microgen, Russia, 614089, Perm region, Perm, st.
Bratskaya, no. 177 and Russia, 603950, Nizhny Novgorod region, Nizhny Novgorod, st. Gruzinskaya, 44 Other drugs from the Bacteriophages group
