Lactofiltrum: features of the use of tablets

1. Compound
2. How does lignin affect the body?
3. For what diseases is taking lactofiltrum indicated?
4. Causes and signs of dysbiosis
5. How to take the drug correctly?
6. Dosages for intestinal dysbiosis and bacterial vaginosis
7. Lactofiltrum for problem skin
8. Is it possible to take Lactofiltrum during pregnancy?

Lactofiltrum is a drug that is used in the treatment of gastrointestinal diseases. The composition of the product includes lactulose and hydrolytic lignin. The drug is available in tablets and sold through pharmacy chains without a prescription. How to take lactofiltrum for adults and children, for what diseases it is effective and who should refrain from taking it - we will tell you in this article.

Pharmacodynamics, pharmacokinetics

Linguine, which is one of the main active ingredients of the drug, is a non-toxic organic compound. It is obtained from wood after careful processing. The substance has good binding properties, it removes from the body:

• Heavy metal salts
• Allergens
• Excess cholesterol
• Excess bilirubin and urea
• Alcohol

After taking the medication, harmful substances are completely eliminated from the body within one day.

Lactulose is the second active ingredient of the drug; it belongs to the prebiotics. The substance blocks the reproduction of pathogenic organisms.

Compound

The active components of lactofiltrum are lactulose and hydrolytic lignin. Lactulose (Lactulosum) is an artificially created lactose-based compound. When lactulose enters the gastrointestinal tract, it has a laxative effect on the intestines. The substance is not absorbed by the mucous membrane, but is only broken down by intestinal bacteria in the colon. This reduces the absorption of water in the intestines, helps soften stool and normalize stool. Products containing lactulose also help improve intestinal motility. The therapeutic effect occurs 1-2 days after taking the drug.

Lignin is a naturally occurring polymer found in plants. It is contained in the intercellular space and cell walls, holding cellulose fibers together. The substance performs the same function in plants as chitin does for insects. Thanks to lignin, tree stems and trunks acquire the necessary rigidity and mechanical strength, which allows them to withstand environmental factors. Lignin contains coloring substances that give wood its natural color.

In nature, lignin is as common as cellulose. The record holder for the amount of lignin is coniferous wood. It contains up to 38% of this substance. In deciduous trees it is slightly less - up to 25%. The source of lignin is also the stems of cereal plants, which consist of 20% of this natural polymer.

How to give Lactofiltrum to children

The drug can be used to treat children over 1 year of age. Regardless of the patient’s age, the drug should be taken 3 times a day. The duration of therapy should be determined by the doctor, but generally the treatment course lasts 14-21 days.

The drug, if there are difficulties with swallowing, can be crushed. You will need warm water for drinking. It is important that the medication must be given to the child an hour before meals. This will help not to interfere with the absorption of nutrients from food and the influence of other pharmaceuticals taken.

How does lignin affect the body?

For the production of medicinal and veterinary drugs, fertilizers and other types of products, hydrolytic lignin is used, which is obtained from plant raw materials. Externally it is a powder. In the Laktofiltrum preparation, this ingredient acts as a sorbent. Unlike pectins and starches, the substance does not dissolve in water. Cellulose has the same properties. Once in the intestine, hydrolyzed lignin is not digested. Like other insoluble fibers, it retains its original structure all the way through the digestive system.

It was once believed that insoluble dietary fiber, also called fiber, did not provide any benefit to the body. They pass through the digestive tract unchanged and practically do not participate in energy exchange. Scientists called such substances ballast, thereby emphasizing their so-called uselessness. In industrial food production, manufacturers used technologies that made it possible to purify plant materials from dietary fiber. It was believed that this approach allows us to obtain products of higher quality and healthier for the body.

Opinion on this issue changed only in the 60s of the last century thanks to the Irish doctor Denis Burkitt. Working in one of the poorest African countries, this specialist noticed that local residents were much less likely to have cardiovascular diseases, diabetes, and constipation. Mr Burkitt suggested it was due to diet. Due to low income, the diet of local residents consisted almost 100% of local products of plant origin: cereals, vegetables, fruits, nuts. They are the main source of fiber.

These facts prompted Denis Burkitt and other specialists to begin a large-scale study that would answer the question of how lignin and other dietary fibers act on the body. At different times, research was carried out by scientists from universities in Northern Ireland, China, and Spain. During the events, we managed to obtain a lot of important and useful information:

• Regular consumption of dietary fiber reduces the risk of developing colon and ovarian tumors.
• Fiber helps normalize blood pressure.
• Lignin and other dietary fiber help normalize stool and get rid of constipation, which negatively affects the entire body.
• Fiber binds and removes toxins and cholesterol from the body.
• When consuming ballast substances, fluctuations in blood glucose become smoother, which reduces the risk of developing diabetes.
• Fiber is a prebiotic, that is, it has a positive effect on the intestinal microflora and creates favorable conditions for the proliferation of beneficial bacteria. Dietary fiber helps restore normal intestinal microflora after treatment with antibiotics, eliminates dysbiosis, improves intestinal motility and helps maintain good intestinal function.
• Fiber creates a feeling of fullness and fills the stomach. This product is useful for people who control their body weight and adhere to a diet.
• Dietary fiber allows you to remove toxins, harmful compounds and microbes from the body. This has a positive effect on appearance and well-being, and helps improve skin condition.

After numerous studies, no one has any doubt about the benefits of lignin and other dietary fiber. The norm of their daily consumption, according to the recommendations of the Ministry of Health of the Russian Federation, is 20 grams. Nutrients can be obtained not only from foods of plant origin, but also from dietary supplements and medications.

Lactofiltrum for acne, how to take

When treating acne, the drug can be effective only if the appearance of acne is caused by a disruption in the digestive tract.

The drug should be taken 1-3 tablets 3 times a day an hour before meals; doctors recommend taking the medicine with water.

The specific dosage should be selected depending on the complexity of the problem. The duration of treatment directly depends on the condition of the skin. The first results will be visible within a day of taking the drug, but it is recommended to complete the entire treatment course, usually it lasts 2 weeks. If necessary, therapy can be repeated after some time.

For what diseases is taking lactofiltrum indicated?

This drug in its composition is a combined enterosorbent, which contains natural sorbent components (lignin) and a prebiotic (lactulose). Lactofiltrum is used as part of complex treatment of the following diseases:

• irritable bowel syndrome;
• intestinal dysbiosis;
• bacterial vaginosis;
• allergic diseases that are accompanied by skin rashes;
• hepatitis and other diseases that are accompanied by decreased liver function.

Lactofiltrum: instructions for use

INSTRUCTIONS

on the medical use of the drug
Lactofiltrum®
Registration number: LSR-008904/08

Trade name of the drug:

Lactofiltrum®

International nonproprietary name or chemical (group) name of the medicinal product:

lactulose + hydrolytic lignin

Dosage form:

pills

Composition per tablet

Hydrolyzed lignin (in terms of dry matter) 355 mg, Lactulose (in terms of 100% matter) 120 mg

Excipients:

croscarmellose sodium 20 mg, magnesium stearate 5 mg, microcrystalline cellulose to obtain a tablet weighing 550 mg

Description:

Capsule-shaped biconvex tablets of dark brown color with white-gray inclusions with a score.

Pharmacotherapeutic group:

enterosorbent

ATX Code:

A07BC

Pharmacological properties:

The pharmacological effect of the drug is due to the properties of the active components - lignin and lactulose.

Hydrolytic lignin is a natural enterosorbent consisting of hydrolysis products of wood components, has high sorbing activity and a nonspecific detoxification effect. Binds in the intestines and removes from the body pathogenic bacteria and bacterial toxins, medications, salts of heavy metals, alcohol, allergens, as well as excess of certain metabolic products, including bilirubin, cholesterol, histamine, serotonin, urea, and other metabolites responsible for the development of endogenous toxicosis.

Non-toxic, not absorbed, completely eliminated from the intestines within 24 hours.

Lactulose is a synthetic disaccharide, the molecule of which consists of galactose and fructose residues. Lactulose is not present in the stomach and upper intestines; absorbed and not hydrolyzed. Lactulose released from the tablets in the large intestine as a substrate is fermented by normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli. As a result of the hydrolysis of lactulose in the large intestine, organic acids are formed - lactic, acetic and formic, which suppress the growth of pathogenic microorganisms and consequently reduce the production of nitrogen-containing toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of the peristaltic.

The complex effect of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.

The use of the drug in complex therapy of bacterial vaginosis (vaginal dysbiosis) leads to an increase in the effectiveness of therapy, including an increase in the number of lactobacilli in the vagina, as well as effective suppression of the growth of opportunistic flora.

Indications for use:

Disorders of the intestinal microflora (intestinal dysbiosis), including as a result of antibiotic therapy; in complex therapy of irritable bowel syndrome, hepatitis and liver cirrhosis; allergic diseases (atopic dermatitis, urticaria), bacterial vaginosis (vaginal dysbiosis).

Contraindications

Individual intolerance to the drug, intestinal obstruction, gastrointestinal bleeding, galactosemia. It is undesirable to use the drug during exacerbation of gastric and duodenal ulcers, or intestinal atony.

Directions for use and dosage:

Orally, if necessary, after preliminary crushing, with water, an hour before meals and taking other medications. For intestinal dysbiosis:

– adults and children over 12 years old – 2-3 tablets 3 times a day,

– children from 8 to 12 years old – 1-2 tablets, 3 times a day,

– children from 3 to 7 years old – 1 tablet, 3 times a day,

– children from 1 year to 3 years – ½ tablet, 3 times a day.

For bacterial vaginosis (vaginal dysbiosis):

2 tablets 3 times a day.

The average duration of treatment is 2-3 weeks.

Long-term use of the drug and repeated courses of treatment should be carried out only on the recommendation of a doctor.

Side effect

Allergic reactions to the components of the drug are possible, rarely - flatulence, diarrhea.

Overdose:

Symptoms:

constipation, abdominal pain.
Treatment:
stop taking the drug.

Interaction with other drugs:

It is possible that the therapeutic effect of some drugs taken orally may be reduced.

special instructions

The drug can be used in complex therapy together with other drugs, subject to the rules of separate administration.

Release form

Pills.

10 or 15 tablets in a blister pack made of polyvinyl chloride film and printed varnished aluminum foil. 30 or 60 tablets in a plastic bottle with a screw cap or in a polymer jar with a screw cap.

1, 2, 3 or 6 blister packs of 10 tablets each, 2 or 4 blister packs of 15 tablets each, or 1 bottle or 1 jar, together with instructions for use, are placed in a cardboard pack.

Storage conditions

In a place protected from moisture and light at a temperature not exceeding 30 °C.

Keep out of the reach of children.

Conditions for dispensing from pharmacies:

Over the counter.

Name and address of the legal entity in whose name the registration certificate was issued/organization receiving claims:

JSC "AVVA RUS", Russia, 121614, Moscow, st. Krylatskie Hills, 30, building 9. Tel/fax avva.com.ru

, Russia, 610044, Kirov region, Kirov, st. Luganskaya, 53a. Tel.,

General Director of JSC "AVVA RUS" Egorov A.G.

Causes and signs of dysbiosis

Intestinal dysbiosis is a pathological condition characterized by an imbalance in the composition of the intestinal microflora. There are more pathogenic and conditionally pathogenic bacteria than beneficial ones. Because of this, the breakdown and absorption of nutrients from the mucous membrane worsens, and its protective functions decrease. If left untreated, dysbiosis can lead to the development of various diseases.

There are enough reasons for pathological changes in microflora. Here are the main ones:

• antibiotic therapy, long-term use of anti-inflammatory drugs;
• intestinal infections;
• alcohol intoxication, stale food poisoning;
• incorrectly selected diet;
• parasitic diseases, other diseases of the intestines and gastrointestinal tract.

People who prefer strict diets with a large number of restrictions, uncontrollably and over a long period of time take activated charcoal and other enterosorbents, laxatives, and do cleansing enemas risk their health.

Negative changes in the composition of the intestinal environment provoke the development of a number of conditions:

• increased gas formation (flatulence);
• gagging or vomiting after eating;
• stomach ache;
• deterioration or loss of appetite;
• indigestion when eating certain foods;
• bloating, which is accompanied by rumbling;
• violation of bowel movements: some people experience loose stools several times a day, sometimes diarrhea alternates with constipation;
• bad breath, not associated with diseases of the teeth and gums.

Impaired bowel function has a negative impact on your appearance and well-being. A lack of nutrients gradually develops, the person becomes lethargic, feels a loss of strength, and irritability. The protective functions of the intestinal mucosa are reduced, so the removal of toxins becomes impossible. Signs of intoxication are headaches, low-grade fever, and decreased performance.

Comparison of drugs

Lactofiltrum and Polysorb

Both Lactofiltrum and Polysorb perfectly cleanse the intestines.

However, they have a number of differences, including:

• Lactofiltrum, unlike Polysorb, is organic in nature.
• The main active ingredient in Polysorb is silicon dioxide, and in Lactofiltrum it is lactulose in combination with lignin. Polysorb only cleanses the intestines, and Lactofiltrum allows you to restore the disturbed microflora.
• Polysorb is available in powder form, and Lactofiltrum is available in tablet form.
• Lactofiltrum is most often prescribed to restore intestinal flora after taking antibacterial drugs. Polysorb is mainly taken to quickly eliminate the symptoms of poisoning, since the effect of taking it develops after 2 minutes.
• They try not to prescribe Lactofiltrum to pregnant women, since its effect on the fetus has not been fully studied. Polysorb can be used by pregnant women to relieve the symptoms of toxicosis.

Enterosgel and Laktofiltrum

• Differences in composition

  . Enterosgel contains modern bioorganic silicon, which is an effective sorbent. Its special porous structure allows it to absorb toxins, but the beneficial intestinal microflora will not be affected. Lactofiltrum is based on lactulose and lignin. The different sizes of lignin pores make it possible to cleanse the body not only of toxins. The drug can also capture and remove beneficial vitamins and minerals. Lactulose is aimed at restoring the colony of beneficial intestinal bacteria.

• Reception features

  . Enterosgel can be taken as much as a person needs, it does not cause addiction to the body, and has no side effects. It is recommended to take Lactofiltrum for no longer than 3 weeks. Moreover, the course of treatment should be supplemented with vitamin and mineral complexes. Otherwise, the likelihood of developing vitamin deficiency increases.

• Contraindications

  . Enterosgel should not be taken only in case of intestinal atony and against the background of internal bleeding. Lactofiltrum has a much wider list of contraindications, which is supplemented by constipation and individual intolerance to the components of the drug. In addition, Lactofiltrum contains auxiliary components that can provoke the development of an allergic reaction.

• Reception comfort

  . Lactofiltrum is produced in tablets and powder, and Enterosgel in the form of a paste. Therefore, at this point the drugs are almost equivalent. If it is difficult for a person to swallow pasty jelly, then you can dilute it with juice or water.

Thus, if we compare these two drugs, Enterosgel becomes the leader. It is highly effective and safe for health. It can be taken for a long time. Therefore, this gel must be in every family’s first aid kit. It is used for poisoning and intoxication, it can be used during a hangover, as well as for weight loss. It helps reduce allergy symptoms.

Lactofiltrum and Filtrum STI

Lactofiltrum and Filtrum STI have different active ingredients. Lactofiltrum contains a synthetic disaccharide - lactulose. It allows you to restore the intestinal flora after infections and also has a slight laxative effect.

Another important difference between the drugs is that Lactofiltrum improves immunity, as it stimulates the growth of beneficial intestinal microflora.

The filter is largely aimed at removing intoxication from the body, as well as eliminating intestinal infections. Lactofiltrum allows you to fight not only the disease, but also eliminate its consequences. Therefore, a doctor who knows his medical history should decide which drug to choose for a particular patient.

It has been proven that Filtrum helps fight allergy symptoms. It binds allergens and removes them from the body. This primarily concerns food allergies.

Contraindications and adverse reactions

The drug should not be taken if:

• intestinal obstruction;
• increased susceptibility to constituent substances;
• hemorrhage in the gastrointestinal tract;
• galactosemia.

It should be taken with great caution in case of intestinal atony and exacerbation of stomach ulcers. The effect of the drug on the condition of a pregnant woman and her unborn child has not been fully studied.

After administration, negative reactions may occur:

• accumulation of gases in the stomach;
• stomach upset;
• allergy.

Improper use of the drug can lead to an overdose, which is manifested by pain in the abdomen or constipation. If you experience such symptoms, you should stop taking it immediately.

Indications for use

Indications for use of the drug Lactofiltrum are:

• Deterioration of intestinal microflora after taking antibacterial drugs.
• Treatment of irritable bowel syndrome.
• Weakened immunity after suffering from infectious diseases affecting the organs of the digestive system.
• Complex treatment of liver cirrhosis.
• Regulating the functioning of the digestive system after suffering from dysbacteriosis.
• Elimination of flatulence phenomena.
• Complex treatment of allergies (atopic dermatitis, urticaria).
• Treatment of colitis.
• Complex treatment of salmonellosis and dysentery.
• Treatment of acne and acne, prevention of hair loss.
• Restoration of the body after intoxication of various origins.
• Complex therapy of viral and bacterial infections.

Side effects

Some patients taking Lactofiltrum experience the following side effects:

• Constipation and bloating
• Diarrhea.
• Abdominal pain.
• Allergic reactions.
• Skin rashes.

The following factors can trigger the development of side effects:

• The person cleanses too intensively and does not follow the recommended dosage.
• A lot of toxins leave the body.
• Metabolic processes accelerate.
• A person has an intolerance to the components that make up the drug.

Release form

Tablets of an oblong biconvex shape with a score in the middle, color - dark brown with light gray specks.

One tablet contains:

• Hydrolytic lignin - 355 mg.
• Lactulose - 120 mg.
• Croscarmellose sodium - 20 mg;
• Magnesium stearate - 5 mg.

Available: in blister packs of 10 or 15 pcs., in plastic bottles of 30 or 60 pcs.

Analogs

The average cost of the drug Lactofiltrum is 306 rubles. Prices can vary from 235 to 650 rubles.

There are no analogues of Lactofiltrum on sale that have an identical composition.

However, there are drugs that have a similar effect:

• Polysorb. This adsorbent starts working very quickly. The first effect will be noticeable within 2 minutes after taking it. The drug is produced by the Russian company Polysorb MP. It is in powder form, which is intended for preparing a suspension. Packaging of the drug: 12, 25, 50 g. For a single dose, you can purchase the drug in sachets of 3 g. The basis of Polysorb is colloidal silicon dioxide. It absorbs harmful substances in the body and removes them out, thereby eliminating the effects of intoxication. The drug can be used while on a diet to reduce excess weight. It allows you to cleanse the intestines and normalize the functioning of the digestive system. The cost of 12 g of the drug is 120 rubles, for a package of 25 g you will need to pay 210 rubles, and for a bag of 50 g you will need to pay 300 rubles. A single dose of the drug costs 49 rubles.
• Polyphepan. This drug is produced in Russia. The production is carried out by the company Saytek. The basis of the drug is hydrolytic lignin. Polyphepan is recommended for use in cases of dysbacteriosis and poisoning of various origins. It is used for weight loss, as it cleanses the body and replenishes the lack of dietary fiber in it. Polyphepan is produced in powder form. Dosage: 50, 100, 200 g. The cost of the drug is 85 rubles.
• Smecta. The drug is available in the form of a powder from which a suspension is prepared. It is supplied to Russia from France (). The basis of the medicine is dioctahedral smectite. The auxiliary components are sodium saccharinate and dextrose monohydrate. Taking the drug allows you to restore damage to the mucous membrane of the stomach and intestines, as well as improve the motility of the digestive system. A distinctive feature of Smecta is its pleasant taste. On sale you can find a drug with the aroma of caramel and cocoa, orange and vanilla. The cost of 10 sachets of the drug is 150 rubles.
• Entegnin. The tablets are produced in Russia. The basis of Entegnin is hydrolytic lignin. The drug has a powerful absorbent effect. It removes urea, bile acid, lipids, poisons and heavy metal salts from the body. It can also be used during a diet as a source of dietary fiber.
• Enterosgel. This drug allows you to relieve the symptoms of intoxication from the body and cleanse the intestines. The drug is available in the form of a paste, which has a sweetish taste. It is taken orally. The drug is produced by the Russian company. After entering the intestinal lumen, the paste swells and, like a sponge, absorbs excess cholesterol and toxins. The cost of a 225 g tube is 380 rubles.
• Filtrum STI. A drug with an absorbent effect based on calcium stearate and povidone. It is used to treat diarrhea, allergies, and poisoning. The drug should not be taken only by those people who suffer from individual intolerance to the components included in its composition. During administration, side effects rarely develop; they are expressed in the form of allergies and constipation. The cost of 10 tablets of the drug is 90 rubles. For a package of 50 tablets you will have to pay 240 rubles. Filtrum STI can be taken during pregnancy and breastfeeding.