Pharmacy No. 84. Delivery of medicines to your home and office.

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Androcur, 10 mg, tablets, 15 pcs.

Androcur®

Inside,

washed down (if necessary) with a small amount of liquid. If signs of disease progression appear, the drug should be discontinued.

Androcur®, 10 mg

To ensure reliable contraception and prevent irregular bleeding, Androcur® is taken in combination with Diane®-35.

Both drugs are started on the 1st day of the cycle (i.e., on the 1st day of menstrual bleeding).

As a rule, take one Androcur® tablet daily from the 1st to the 15th day of the treatment cycle in addition to Diana®-35.

In the package, each tablet is marked with the day of the week on which it should be taken. You should take one tablet of Androcur® and Diane®-35 at the same time every day with a small amount of water. It is necessary to follow the direction of the arrow until all 15 tables. Androcur® will not be accepted. In the next 6 days, only Diane®-35 is taken.

When, after 21 days of taking the calendar pack of Diane®-35, the drug runs out, there should be a 7-day break in taking the pills, during which menstrual-like bleeding should begin.

After a 7-day break, regardless of whether the menstrual bleeding has stopped or is still ongoing, taking the tablets is resumed from the following calendar packs of Androcur® and Diane®-35.

If menstrual bleeding does not occur during the break, which is extremely rare, treatment should be interrupted and do not resume taking the pills until pregnancy has been ruled out.

Taking missed pills

If the patient forgot to take the Diane®-35 tablet at the usual time, then this should be done no later than within the next 12 hours. If more than 12 hours have passed since the usual time of taking Diane®-35, the contraceptive effect in this cycle may be weakened. It is necessary to pay attention to special notes regarding contraceptive reliability, as well as recommendations for missed pills, which are included in the information about the drug Diane®-35. If there is no menstrual-like bleeding after this cycle, pregnancy should be ruled out before resuming taking the pills.

Skipping Androcur® tablets may lead to a decrease in the therapeutic effect and cause menstrual-like bleeding. Do not take the missed Androcur® tablet (i.e. do not take a double dose to compensate for the missed tablet) and resume taking the drug at the usual time along with Diane®-35.

The duration of treatment depends on the severity of the pathological signs of androgenization and their dynamics during treatment. The drugs must be taken for several months. The therapeutic effect for acne and seborrhea usually manifests itself faster than for hirsutism and alopecia.

After achieving clinical improvement, you should try to continue treatment with Diane®-35 only.

Use in certain categories of patients

Childhood and adolescence.

Efficacy and safety have not been studied in clinical trials in children or adolescents under 18 years of age.

Elderly age.

The drug Androkur® is indicated only for women of reproductive age.

Liver failure.

The use of Androcur® is contraindicated in patients with liver disease.

Kidney failure.

There is no data on the need to change the dose in this category of patients.

Androcur®, 50 and 100 mg

Antiandrogen therapy for inoperable prostate cancer:

200–300 mg/day (2 tablets of Androcura® 50 mg or 1 tablet of Androcura® 100 mg 2–3 times a day, long-term).

If the condition improves or remission is achieved, treatment should not be interrupted or the dosage reduced.

To reduce the initial increase in androgen levels during GnRH agonist therapy:

Initially, 200 mg per day (2 tablets of Androcura® 50 mg or 1 tablet of Androcura 100 mg 2 times a day) as monotherapy for 5–7 days, then 200 mg per day for 3 –4 weeks in combination with a GnRH agonist at the manufacturer’s recommended dosage.

For the treatment of hot flashes during therapy with GnRH analogues or after orchiectomy:

50–100 mg/day (1–3 tablets of Androcura® 50 mg or 0.5–1.5 tablets of Androcura® 100 mg per day), if necessary, followed by increasing the dose to 300 mg per day (according to 2 tablets of Androcura® 50 mg or 1 tablet of Androcura® 100 mg 3 times a day).

Androcur®, 50 mg

With increased libido and sexual disorders.

As a rule, treatment begins with 1 tablet. drug Androkur® 50 mg 2 times a day. If necessary, the dose can be increased to 200–300 mg per day (2 tablets 2–3 times a day) for a short period. If a satisfactory result is achieved, you should try to reduce the dose of the drug to the minimum effective. In most cases, it is enough to take 50 mg/day (1/2 tablet 2 times a day). When selecting a maintenance dose or discontinuing therapy, the dose should be reduced gradually. For this purpose, it is recommended to reduce the daily dose by 1 tablet, or better by 0.5 tablets, at intervals of several weeks. To achieve a sustainable therapeutic effect, Androcur® should be taken for a long time, if possible with simultaneous psychotherapy.

Use in certain categories of patients

Childhood and adolescence

Androkur® is not recommended for use in children and adolescents under 18 years of age due to insufficient information on effectiveness and safety in this category of patients.

Elderly age.

There is no data on the need to change the dose of the drug in elderly patients.

Liver failure.

The use of Androcur® is contraindicated in patients with liver disease (until liver function tests are normalized).

Kidney failure.

There is no data on the need to change the dose in this category of patients.

Androkur® Depot

V/m,

slowly, deep into the muscle.

Like all oil solutions, Androcur® Depot is administered only intramuscularly and very slowly. In some cases, pulmonary oil microembolism may cause signs and symptoms such as cough, shortness of breath, and chest pain. Other signs and symptoms may also occur, including: vasovagal reactions (eg malaise, increased sweating, dizziness, paresthesia or fainting). These reactions may occur during or immediately after the injection and are reversible. In such cases, supportive therapy (eg oxygen inhalation) is usually used. Intravascular administration of the drug should be avoided.

Antiandrogen therapy for inoperable prostate carcinoma:

300 mg IM every 7 days.

If the condition improves or remission is achieved, treatment should not be interrupted or the dosage reduced.

Decreased libido due to sexual deviations:

Usually 300 mg (1 amp.) IM every 10-14 days. In exceptional cases, when this dose is not enough, 600 mg (2 amps) can be administered every 10–14 days (preferably 3 ml in the right and left buttock). When a satisfactory treatment result is achieved, you should try to reduce the dose, gradually increasing the intervals between injections.

To achieve a sustainable therapeutic effect, Androcur® Depot should be taken for a long time, if possible with simultaneous psychotherapy.

Use in certain categories of patients

Childhood and adolescence

Androcur® Depot is not recommended for use in children and adolescents under 18 years of age due to insufficient information on effectiveness and safety in this category of patients.

Elderly age.

There is no data on the need to change the dose of the drug in elderly patients.

Liver failure.

The use of Androcur® Depot is contraindicated in patients with liver disease (until liver parameters return to normal).

Kidney failure.

There is no data on the need to change the dose in this category of patients.

Androcur® (Androcur®)

To ensure reliable contraception and prevent irregular bleeding, Androcur® is taken in combination with Diane®-35.

Both drugs are started on the 1st day of the cycle (that is, on the 1st day of menstrual bleeding).

As a rule, take one Androcur® tablet daily from the 1st to the 15th day of the treatment cycle in addition to Diana®-35.

In the package, each tablet is marked with the day of the week on which it should be taken. You should take one tablet of Androcur® and Diane®-35 at the same time every day with a small amount of water. Follow the direction of the arrow until all 15 Androcur® tablets have been taken. In the next 6 days, only Diane®-35 is taken.

When, after 21 days of taking the calendar pack of Diane®-35, the drug runs out, there should be a 7-day break in taking the pills, during which menstrual-like bleeding should begin.

After a 7-day break, regardless of whether the menstrual bleeding has stopped or is still ongoing, taking the tablets is resumed from the following calendar packs of Androcur® and Diane®-35.

If menstrual bleeding does not occur during the break, which is extremely rare, treatment should be interrupted and do not resume taking the pills until pregnancy has been ruled out.

Taking missed pills

If the patient forgot to take Diane®-35 tablet at the usual time, this should be done no later than within the next 12 hours. If more than 12 hours have passed since the usual intake of Diane®-35, the contraceptive effect in this cycle may be weakened. It is necessary to pay attention to special notes regarding contraceptive reliability, as well as recommendations for missed pills, which are included in the information about the drug Diane®-35. If there is no menstrual-like bleeding after this cycle, pregnancy should be ruled out before resuming taking the pills.

Skipping Androcur® tablets may lead to a decrease in the therapeutic effect and cause menstrual-like bleeding. The missed tablet of the drug is not taken (i.e., you should not take a double dose to compensate for the missed tablet) and the drug is resumed at the usual time along with the drug Diane®-35.

The duration of treatment is determined by the doctor depending on the severity of the pathological signs of androgenization and their dynamics during treatment. The drugs must be taken for several months. The therapeutic effect for acne and seborrhea usually manifests itself faster than for hirsutism and alopecia.

After achieving clinical improvement, you should try to continue treatment with Diane®-35 only.

Use in certain categories of patients

Childhood and adolescence

Efficacy and safety have not been studied in clinical trials in children or adolescents under 18 years of age.

Elderly age

The drug Androkur® is indicated only for women of reproductive age.

Liver failure

The use of Androcur® is contraindicated in patients with liver disease.

Kidney failure

There is no data on the need to change the dose in this category of patients.