Citramarin pack (portable orange oral solution) 13g No. 10 Marbiopharm/Russia
Important. If the location “Online Pharmacy” is selected in the site menu, ordering the product is possible only at the “Price to order” based on suppliers’ offers. If suppliers do not have goods, only the “Subscribe” option is available if the old price is known, or “To order” when there is no information on the old prices. We ask you to pay attention to the “Availability” Tab - you can order goods at the balances and prices of pharmacies, but to do this you need to select the desired pharmacy in the site menu (next to the “Your pharmacy” field).
This section provides answers to frequently asked questions from visitors to our site.
What is the minimum order amount?
The minimum order amount for regular customers when purchasing from a pharmacy is 400 rubles.
The minimum order amount for regular customers when delivering by courier is RUB 1,500. The minimum order amount for legal entities purchasing goods for their own needs is 400 rubles. Can I get an additional discount?
There are no discounts on the site.
We simply gave up discounts and set a minimum markup on goods, and try to keep prices at such prices that it turns out even cheaper than with the maximum possible discount, and these prices are for all our customers. Accordingly, the discount does not apply to online orders made through. These orders are already at the minimum price, since when ordering, the minimum price is automatically selected from the price at the pharmacy and the price to order. Usually the price “to order” is cheaper than in a pharmacy, it comes to order, with a guarantee of quick redemption, and accordingly the markup is lower than in a pharmacy, since there is no need to keep the goods in stock. If the product is available in the pharmacy and the price in the pharmacy is cheaper, then we take the pharmacy price for this item as a basis.
Can I change my order after I have submitted it?
Adjustment of goods, quantity, change of point of issue, etc.
after you send your order is possible only by the manager after we receive the order, when the manager contacts you to clarify the order. In the buyer's personal account, only the ability to cancel or repeat orders is available. To adjust your order, you need to contact the contact manager of the pharmacy - the order pick-up point indicated on the “Contacts” page of the website. Can I contact the pharmacy myself to find out if my order has arrived?
You can call the pharmacy using the numbers listed on the website.
OUR PHARMACIES, ADDRESSES, TELEPHONES What will happen to my order if I don’t buy it within 5 days, and when can I pick it up later?
If you have not purchased your order within 5 days, your order will be canceled and the product will be put up for sale at the retail price in the pharmacy. And you will have to make a new order on the website.
If you ordered a product on the website and did not come for it within 5 days from the date of receipt, your data will be blacklisted (emergency), and a new order will be possible only after making a deposit on the order in the amount of 30% of its cost. If you refuse to purchase your order, the deposit amount will not be returned.
When you first add to an emergency situation, a warning is sent that the next time you find yourself in an emergency situation again, you will not be able to place orders.
Those buyers who systematically do not redeem their orders on time, as well as those who do not buy all the goods from the order, but only part of them, also fall into emergencies.
If I cannot pick up my order on the day it arrives at the pharmacy, can I redeem it later?
Your order is stored in the Pharmacy for 5 days from the date of receipt, during which time you can pick up your order.
When can I receive my product after ordering?
After sending the order, an SMS message about the order will be sent to the mobile phone number you specified, for example: “Zdravstvujte, Vladimir! Vy oformili zakaz No. 1234 na summu RUR 2345.50 Ozhidajte zvonka iz apteki.”, then during the working day, from 9-00 to 17-30, the APTEKA-INFO.RU service manager will contact you to confirm your application, then the application will be sent to the supplier , will be collected there and delivered to the pharmacy of your choice on the next business day.
Important.
Applications are processed only on weekdays from 9-00 to 17-30.
Applications accepted and processed on Friday will be delivered to the pharmacy on Monday or Tuesday. It is possible to speed up the order readiness; the exact date of order readiness is agreed upon with the manager. Applications received on weekends (Saturday, Sunday) will be accepted and processed on the next business day, and delivered on Tuesday-Wednesday.
When agreeing on an order, we warn you about the approximate time frame for the entire order to be ready in order to avoid misunderstandings.
How will I know that my order has been delivered to the pharmacy?
When the goods arrive at the pharmacy, you will receive a letter about the readiness of your order and an SMS notification, then they will call you and inform you that you can come and pick up your order. If you do not redeem your order within 1-2 days from the moment it is ready, they will call you and remind you that it is ready.
Important.
All letters and SMS are sent automatically when the status of the order changes, but sometimes situations are possible when the letter and SMS are ahead of the delivery of your order to the pharmacy, mainly due to an error by the workers processing the order.
A phone call from the pharmacy is a 100% guarantee that your order has already arrived at the pharmacy and you can receive it. So please wait for this call.
If you want to clarify the status of your order, you need to call the pharmacy where the order is issued and provide your name and order number.
Is it possible to pick up the ordered goods?
Pickup is the main way to receive an order on our service, since most orders contain medications that we cannot deliver to you by courier.
You can independently pick up the ordered goods at our pharmacies - delivery points, this is convenient, we have 4 pharmacies in Tomsk and 1 in Seversk. How is delivery to the regions carried out?
Delivery to regions is not possible.
We work only in Tomsk and Seversk. Is it possible to order medicine to be delivered to your home?
The delivery of prescription drugs is prohibited by the current legislation of the Russian Federation.
Delivery of over-the-counter medicines is permitted only if there is a license for the remote sale of medicines.
APTEKA-INFO is working to resolve the delivery issue, but unfortunately we do not yet have the necessary license, so home delivery is not possible.
We deliver orders containing medications only to our pharmacies.
You can choose any pharmacy convenient for you from those presented on and redeem your order at the selected pharmacy.
There are prescription drugs on the site, can I order them and get them at the pharmacy?
You can order prescription goods, but when purchasing from a Pharmacy for any prescription drug, you have the right to require a prescription, and if you do not have a prescription, the Pharmacy has the right not to issue your order. When confirming an order by the buyer at the stage of its pre-processing, the service manager usually always checks whether the buyer has a prescription; if it is not available, prescription products are excluded from the order. The items in your order are not a single item, and you will be able to receive over-the-counter drugs included in your order.
Attention!
Buyers who regularly fail to redeem part or all of their orders risk being blacklisted. If a buyer is blacklisted, a restriction is included - when ordering rare drugs and goods, the pharmacy has the right to demand from the buyer:
1) making a deposit - if, when the buyer refuses to buy these goods, the service has problems with further sales, since the goods are very rare, are not in rare and everyday demand, or the supplier refuses to return such goods. The deposit amount in this case is not refundable.
2) making an advance payment - if the product is rare, but it is still bought by ordinary customers in pharmacies.
Making an advance payment in this case is an additional guarantee that the buyer really intends to purchase this product. In case of cancellation of the purchase, the advance payment is returned to the buyer in full. Why do “to order” prices on the website differ from prices in pharmacies?
We try to keep prices minimal for our clients, so prices for drugs on our website are usually lower than in pharmacies and apply only to online orders made on the website.
The “made to order” price is formed based on suppliers’ proposals. Prices in a pharmacy are individual, since prices from suppliers change every day, all pharmacies work independently and receive goods on different days and months, so prices in pharmacies are all different. If you urgently need medicine on the same day, and at a low price, you can find information about the availability and prices of the product on its page, in the “Availability” tab, there is information about stock and prices in our pharmacies.
How can an organization purchase medicines and goods?
Due to the introduction of labeling for drugs, a large number of labeled drugs, and the lack of profitability of this activity, we are forced to stop working with legal entities on drugs that have a labeling sign.
Therefore, on our website, legal entities can no longer purchase medicines and medical products by bank transfer.
The opportunity to register and place orders remains available for legal entities. But working by bank transfer and receiving sales and accompanying documents for orders is impossible.
We continue to accept applications from medical centers, hospitals, medical institutions, medical units, beauty salons, private offices, etc., who need medicines and over-the-counter medicines and other goods and medical products that do not have a label, as well as parapharmaceutical products for “own needs”, as well as from organizations that maintain their production first aid kits fully equipped.
Our conditions and a brief procedure for working with legal entities:
- The minimum order amount for legal entities was previously 3,000 rubles, now it is 400 rubles.
- The purchasing organization registers on the website apteka-info.ru, where it can then create an order.
- To receive information about the order and its approval, the purchasing organization sends a request to the email address and also provides the order number.
- A supply agreement is not concluded with a legal entity, since the purchasing organization buys the online order in cash, at retail, in the same way as ordinary buyers - individuals.
- After receiving the order and agreeing on the terms of sale of medicines and other goods, APTEKA-INFO LLC accepts the online order and orders the goods from suppliers.
- After receiving the goods from the supplier, the order is collected and prepared for delivery.
- The delivery of the goods occurs after its preparation and assembly, pick-up at the addresses of the pharmacies of APTEKA-INFO LLC. The purchase period for the order by the buyer is 7 days from the date of readiness. Only cash receipts and sales receipts are provided with the goods. Certification documents for goods are provided upon special prior request.
You can also place an order:
- by sending a letter to
- by calling 8-3822-609-839.
Our specialist will advise you on the products, check their availability and calculate the cost of the order.
Is the price of the product on the website inclusive of VAT?
LLC "APTEKA-INFO", operating under the brand "APTEKA-INFO", applies a simplified tax regime (without VAT).
Didn't find the answer to your question?
Contact us and we will provide the necessary information.
EVRYSDI powder 0.75 mg/ml 2 g No. 1 bottle + adapter + syringes
Content
Pharmacological action Indications Dosage regimen Side effects Contraindications for use Use during pregnancy and breastfeeding Use for impaired liver function Use for impaired renal function Use in children Special instructions Drug interactions Storage conditions Shelf life
pharmachologic effect
Risdiplam is a survival motor neuron 2 (SMN2) gene precursor messenger ribonucleic acid (pre-mRNA) splicing modifier developed for the treatment of spinal muscular atrophy (SMA), which is caused by mutations on chromosome 5q that result in deficiency of the SMN protein. Lack of functional SMN protein is a pathophysiological mechanism for the development of all types of SMA. Risdiplam corrects SMN2 splicing, shifting the balance from exon 7 exclusion to exon 7 inclusion in the mRNA transcript, resulting in the formation of a functional and stable SMN protein. Thus, risdiplam treats SMA by increasing and maintaining functional SMN protein levels.
Risdiplam is distributed evenly throughout the body, incl. in the CNS, penetrating the BBB and accordingly leading to an increase in the level of SMN protein in the CNS and throughout the body. Concentrations of risdiplam in plasma and SMN protein in blood reflect the distribution and pharmacodynamic effects of risdiplam in tissues, namely muscle tissue and brain tissue.
In all clinical studies, risdiplam resulted in a sustained and long-lasting increase in SMN protein levels. Within 4 weeks of treatment, the median SMN protein level was more than 2-fold higher than baseline, as measured in blood. Increases in SMN protein levels were maintained over a treatment period of <2 years in patients with SMA onset in infancy and in patients with late onset SMA.
Indications
Treatment of spinal muscular atrophy in adults and children from 2 months.
Dosage regimen
The method of administration and dosage regimen of a particular drug depend on its release form and other factors. The optimal dosage regimen is determined by the doctor. The compliance of the dosage form of a particular drug with the indications for use and dosage regimen should be strictly observed.
Inside, 1 time/day. The daily dose is set depending on age and body weight.
Side effect
- From the digestive system: very often - diarrhea.
- From the skin and subcutaneous fat: very often - maculopapular rash, erythema, dermatitis, allergic dermatitis, papular rash, folliculitis.
Contraindications for use
Hypersensitivity to risdiplam; pregnancy, breastfeeding period; children up to 2 months old.
Use during pregnancy and breastfeeding
Use during pregnancy and breastfeeding is contraindicated.
Use for liver dysfunction
No dose adjustment is required in patients with mild or moderate hepatic impairment. Use in patients with severe hepatic impairment has not been studied.
Use for renal impairment
There is no need for dose adjustment in patients with impaired renal function.
Use in children
Contraindicated for use in children under 2 months of age.
special instructions
Embryofetal toxicity
When studying the use of the drug in animals, embryofetal toxicity was observed. Patients of reproductive potential should be informed of the risks and use highly effective methods of contraception during treatment and for at least 1 month after the last dose of Evrysdi by a female patient and for at least 4 months after the last dose of Evrysdi ® male patient.
Possible effect on fertility in men
The reversible effect of Eurysdi® on male fertility was shown in an animal study. In this regard, male patients should not be sperm donors during treatment and for 4 months after taking the last dose of Eurysdi®.
Liver dysfunction
The pharmacokinetics, safety and tolerability of risdiplam 5 mg were assessed in subjects with mild to moderate hepatic impairment in a dedicated clinical trial.
Mild to moderate hepatic impairment did not affect the pharmacokinetics of risdiplam. Thus, patients with mild or moderate hepatic impairment do not require dose adjustment. The use of Evrysdi® in patients with severe liver dysfunction has not been studied.
Drug abuse or drug dependence.
Evrysdi® does not have the potential to lead to drug abuse and drug dependence.
Drug interactions
No clinically significant interactions with other drugs have been established.
Storage conditions
At a temperature not exceeding 25 °C in the original packaging (bottle in a cardboard box).
Best before date
2 years.
Do not use after the expiration date.
Store the prepared solution in the original bottle with a tightly closed lid in an upright position at a temperature of 2-8 ° C for 64 days, do not freeze.
