Phenazepam is one of the drugs that can have a calming effect on the human central nervous system. In fact, it is a highly active tranquilizer.
A special feature of the drug is its superiority over other tranquilizers due to the strength of its anxiolytic and tranquilizing effects. In addition, the drug performs the following functions:
- anticonvulsant;
- sleeping pills;
- muscle relaxant (muscle relaxation) agent.
It is important to remember that taking Phenazepam together with narcotic and sleeping pills creates the effect of increasing the impact on the state of the central nervous system.
The drug is available in the form of 0.5 mg tablets. The package contains 50 tablets. Price – 90-100 rubles. Produced in Russia.
Features and purposes of application
The drug is prescribed in the following cases:
- psychopathic;
- psychopathic;
- neurotic;
- neurosis-like state.
As a rule, in such situations there is an emphasized state of anxiety, fear, and often increased irritability and instability (emotional lability).
Phenazepam has confirmed its effectiveness in eliminating problems such as obsessive neuroses, a variety of human fears (phobias), and hypochondriacal syndromes. What is important is that it demonstrates results where other tranquilizers are unable to overcome resistant syndromes.
If we take into account the anti-anxiety and calming (sedative) effect of the drug, it turns out that it is not inferior to a number of neuroleptics, that is, those drugs whose action is aimed at an inhibitory effect.
Phenazepam is often prescribed to patients to eliminate alcohol withdrawal, a phenomenon that occurs after a sudden refusal to take alcoholic substances. It is also a sleeping pill. In terms of its hypnotic properties, it approaches the level of Eunoctine.
Reviews on the choice of Phenazepam analogues
Reviews about Phenazepam are positive. Psychiatrists, dermatologists and neurologists note its high effectiveness in relieving neurological and mental attacks. Patients respond positively to Phenazepam due to its low toxicity to the body. Reviews about the presented analogues are not so clear:
- Catalina S.V., neurologist: “I prescribe Phenazepam to patients with neuroses, a depressed and depressed state, as well as with neurasthenia. Phenazepam is especially effective in relieving the negative symptoms of nervous tension in women with PMS and menopause. Also, in my neurological practice, I often use Relanium, Gidazepam and Glycine instead of Phenazepam in the treatment of various neurotic pathologies. The effectiveness of these medications has been proven by time, although Glycine, of course, acts much more gently and longer, but sometimes this is exactly what is needed. "
- Svetlana, 51 years old: “After the death of my son, I developed severe depression, apathy, thoughts of suicide and insomnia. My family saved me a little from depression, but insomnia simply worsened my negative mental state. The doctor prescribed me Phenazepam. After just a week of therapy, my sleep improved and I began to get enough sleep. Phenazepam really helped me. Then the doctor said that it was time to change it and prescribed Alprozolam - no effect, panic attacks returned, I stopped sleeping. I went back to Phenazepam again.”
Phenazepam is one of the most effective antipsychotics, which is used in dermatology, neurology and psychiatry. The medication is prescribed by a doctor, who also adjusts the dosage and regimen. If necessary, the doctor can also prescribe its analogues instead of Phenozepam.
Why do people look for analogues?
It is now easy to abandon Phenazepam in favor of another drug: every year there are more and more analogues. Their appearance is also due to the fact that Phenazepam turned out to be a drug with numerous disadvantages: its popularity is gradually declining.
Perhaps the most important drawback, which not only experts, but also patients paid attention to, was the addiction and dependence that occurred when using pills. Discoordination that occurs after using the drug has become a real problem for older people who are at risk of injury.
It turned out that giving up the drug is not so easy. Doctors note the presence of a pronounced withdrawal syndrome - when, after a long time of using Phenazepam, patients, after stopping its use, experience irritability, anxiety, depression, increased sensitivity to light and sounds, increased tactile hypersensitivity, tachycardia, and convulsions.
What it really is:
Analogs for therapeutic effect
Similar drugs to Phenazepam in terms of therapeutic effect are medications that have different component compositions with Phenazepam, but the same therapeutic direction.
Sonapax
Sonapax is an antipsychotic drug that is produced in tablets with the active ingredient - thioridazine hydrochloride. The drug is prescribed for:
- schizophrenia and paranoia;
- involutional psychosis;
- severe psychosomatic disorders;
- depression with anxiety and fear syndrome;
- alcohol syndrome;
- severe itching on the skin of allergic etiology;
- impaired behavioral activity of children and adolescents.
The medication is not used in treatment for:
- allergies to the composition;
- deep depression;
- pheochromocytoma;
- pathologies in hematopoiesis;
- porphyria.
Sonapax is not used in pediatric practice under 4 years of age and during breastfeeding. Not prescribed during pregnancy in the 1st trimester, as well as in the last week of pregnancy.
Dragees are taken orally according to dosages personally prescribed by the doctor. Average dosages of Sonapax per day:
- schizophrenia, agitation, depression and other mental disorders - 250-800 mg for 1-4 months.
- patients over 65 years old – 30-100 mg;
- emotional and psycho-emotional pathologies – 30-200 mg;
- psychosomatic disorders – 10-75 mg. The daily maximum is 200 mg.
For children, medication is prescribed individually for each child.
Negative symptoms:
- dizziness and drowsiness;
- lethargy and depression;
- dyspepsia;
- decreased blood pressure, anemia and tachycardia;
- urinary retention;
- bronchospasms, allergic rashes and itching on the skin.
Alprazolam
Alprazolam is an antipsychotic and is made in tablet form with the main ingredient alprozolam. The drug is prescribed for:
- neuroses and psychoses;
- nervousness-like and psychomotor overexcitation;
- anxiety syndrome;
- reactive depressive psychosis;
- irritability and aggression;
- depression and suicidal actions and thoughts;
- apathetic state;
- panic and causeless anxiety;
- paranoia and phobias.
Do not use the medicine if:
- coma;
- allergic reaction to a medicinal composition;
- myasthenia gravis;
- cardiac disorders - arrhythmia, angina pectoris and cardiogenic shock;
- intoxication with psychotropic, neuroleptic and hypnotic drugs, as well as ethanol and drugs;
- respiratory failure.
Alprazolam is not used in pediatric practice or during breastfeeding pregnancy.
Dosages are prescribed in accordance with the pathology being diagnosed and the degree of its progression. The medicine should be taken 2-3 times a day:
- panic states and depression - initial 0.1-0.2 mg, therapeutic - 5-6 mg;
- anxiety syndrome - 0.7-1.5 mg for 2 weeks, then increased to a therapeutic dose - 10 mg.
Side effects:
- allergic rashes on the epidermis and itching;
- drowsiness and dizziness;
- lethargy and poor coordination;
- dyspepsia;
- fatigue, low blood pressure and arrhythmia.
Gidazepam
Gidazepam is a neuroleptic anticonvulsant drug with tranquilizing and muscle relaxant properties. The main component is gidazepam. Gidazepam is produced in tablets and is prescribed for:
- development of neurotic conditions;
- psychopathic states;
- psychosis;
- syndromes of fear and anxiety;
- overstrain of the central nervous system and psyche;
- aggressiveness, nervous and irritable behavior;
- insomnia;
- paranoid and suicidal thoughts;
- depression.
The drug should not be prescribed for:
- hypersensitivity to the components in the composition;
- myasthenia gravis;
- kidney dysfunction;
- pregnancy and pediatrics;
- breastfeeding.
A single dosage of Gidazepam is 2-5 mg. The medication should be taken twice or thrice a day. If the dosage is ineffective, then the doctor doubles it.
For psychosis, you need to take 0.06-0.2 g per day, for a neurotic disorder - 0.05-0.2 g.
Side effects:
- headache;
- decreased libido;
- impotence in men;
- drowsiness;
- dyspepsia;
- muscle weakness;
- skin allergies.
Relanium
Relanium is an antipsychotic with the main component – diazepam. Relanium is produced in tablet form and in parenteral solution.
Relanium is prescribed for:
- convulsive and epileptic seizures;
- psychomotor and nervous overexcitation;
- disruption of the blood supply to brain cells;
- tetanus;
- withdrawal syndrome;
- disruption of the menstrual cycle;
- systemic and cardiac pathologies - hypertension and arrhythmias.
You should not take the medicine if:
- sensitivity to components;
- myasthenia gravis;
- alcoholism, drug addiction and drug dependence;
- apnea;
- liver/kidney dysfunction.
Relanium is not prescribed in the 1st and 3rd trimester of pregnancy, and is also not used in the treatment of children under 3 years of age and nursing women.
For acute neuroses and psychoses, 10-20 mg is administered parenterally. If the attack progresses, then injections must be given at intervals of 4 hours. After the condition has stabilized, the patient is transferred to an oral form of therapy.
Side symptoms:
- drowsiness and confusion;
- dizziness and hallucinations;
- depression and irritability;
- dyspepsia;
- decreased blood pressure, arrhythmia and tachycardia;
- swelling of the limbs and face;
- skin rash and itching.
The best of the best or how to replace Phenazepam?
In the pharmaceutical industry you can find a whole list of chemicals that are analogues of Phenazepam. Among the most famous are Diazepam, Elzepam, Oxazepam, Fezanef, Fenzitate, Tranquesipam, Fesipam, Phenorelaxan and others. All of them are tranquilizers, moreover, benzodiazepine derivatives.
This means that a certain amount of the negative qualities that Phenazepam has are also present in its analogues.
Let's look at the most popular analogues of Phenazepamam, dividing them into three groups; in total, we have selected 15 drugs that, in our opinion, are worthy of attention.
The first group will contain drugs that provide a completely comparable effect to Phenazepam, belonging to the same group of benzodiazepine drugs:
- Fenzitate is a tranquilizer, a benzodiazepine derivative, which has a pronounced anxiolytic, anticonvulsant, muscle relaxant, sedative and hypnotic effect.
- Fezanef is a tranquilizer. Used for the treatment of neurotic, neurosis-like, psychopathic and other conditions that are accompanied by anxiety, fear, increased irritability, tension, and emotional lability.
- Fesipam is a drug with pronounced anxiolytic, anticonvulsant, muscle relaxant, sedative and hypnotic effects.
- Tranquesipam is a drug that has a pronounced anxiolytic, hypnotic, sedative, as well as anticonvulsant and central muscle relaxant effect.
- Phenorelaxan . The drug is used as an antipsychotic for schizophrenia; also for the treatment of athetosis, vegetative lability; with premedication; as a means of facilitating overcoming feelings of fear and emotional stress.
- Elzepam . The drug is used to treat neurotic, neurosis-like, psychopathic, psychopath-like and other conditions that are accompanied by anxiety, fear, increased irritability, tension, and emotional lability.
In the second group, we selected over-the-counter analogues of Phenazepam, which can be bought freely at the pharmacy. They are harmless to the human body. This:
- Amitriptyline . Use strictly as prescribed by your doctor. Used to treat depression of any etiology. It is especially effective for anxiety and depression due to the severity of the sedative effect. Does not cause exacerbation of productive symptoms (delusions, hallucinations), unlike antidepressants with a stimulating effect.
- Etaperazine . Used for the treatment of mental illnesses - schizophrenia, exogenous and involutional senile psychoses, psychopathy, indomitable vomiting, including during pregnancy.
- Glycine . It is a regulator of metabolism, normalizes and activates protective inhibition processes in the central nervous system, reduces psycho-emotional stress, and increases mental performance.
- Sonapax . Used for the treatment of schizophrenia - as a second-line drug in patients for whom other drugs are contraindicated, or for whom there is no therapeutic effect when taking other drugs; severe behavioral disorders associated with aggressiveness, inability to concentrate for long periods of time.
- Bellatominal is used for increased irritability, insomnia, neurogenic disorders of the menstrual cycle, to relieve itching in neurodermatitis, and in the complex therapy of vegetative-vascular dystonia.
- Melaxen – helps normalize sleep; the drug is most effective in the treatment of elderly patients with primary insomnia.
- Adaptol - used for neuroses and neurosis-like conditions - irritability, emotional instability, anxiety, fear; nicotine withdrawal (as part of complex therapy to reduce the desire to smoke tobacco).
The last group includes drugs that can replace Phenazepam as a sleeping pill. Let's name the two most famous herbal remedies in this group:
- Nason is a combination drug of plant origin. Used for sleep disorders (disturbances in the process of falling asleep, frequent awakenings at night, with a tendency to short-term sleep at night due to restlessness, anxiety, tension or irritability).
- Persen . Used to treat neuroses that do not require the use of potent drugs; for the withdrawal of potent sedatives.
Phenazepam: pharmacological features
Phenazepam is a potent tranquilizer based on the active substance bromodihydrochlorophenylbenzodiazepine. Phenazepam tablets are used in the treatment of various neuropsychiatric disorders accompanied by anxiety or fear syndrome.
Main indications for the use of a tranquilizer:
- alcohol withdrawal;
- alcohol, drug or drug intoxication of the body;
- neurosis;
- psychosis;
- phobias;
- epilepsy;
- hypochondriacal syndrome.
Phenazepam acts directly on the central nervous system, due to which it is widely used in neurosis-like, neurotic, psychopathic and psychopath-like conditions. Most often, such pathologies are accompanied by a feeling of panic, anxiety, increased irritability and emotional instability.
It is recommended to drink the pharmacological drug in a minimum dosage - no more than 0.25-0.5 tablets.
Phenazepam is sold in pharmacies only with a doctor's prescription. According to the law, this tranquilizer is included in the Register of Substances Subject to Special State Control. This resolution is enshrined in the Single Convention on Narcotic Drugs at the proposal of the UN.
Melaxen is the most famous over-the-counter analogue
Melaxen is officially an over-the-counter analogue of Phenazepam.
It’s worth clarifying right away: if a medical product is over-the-counter, this indicates its high level of safety for humans.
Melaxen can be taken independently by those who are trying to eliminate insomnia. The drug as a whole is a chemical analogue of melatonin, a natural sleep hormone. Consequently, it acts in the body quite organically.
This means that the patient’s sleep phases are not disturbed, and sleep itself becomes restorative, complete rest.
Using Melaxen will relieve such troubles as daytime sleepiness, incoordination, nightmares and attention or memory problems.
Symptoms of phenazepam withdrawal syndrome:
- Sleep is disturbed.
- Anxiety arises.
- Anxiety is growing.
- The person becomes irritable
- Discomfort in the heart area, headache, loss of appetite, and nausea are noted.
- In severe cases, psychosis may develop with impaired consciousness and vivid, often frightening, hallucinations.
- Urinary incontinence occurs not only during sleep, but also during the daytime.
- Convulsive seizures of the epileptic type may occur.
Drug dependence on phenazepam develops with long-term systematic use. Its symptoms are close to drug addiction. Stopping the abuse of this drug is difficult, and without medical supervision and control it is almost impossible and dangerous.
In severe cases, psychosis may develop with impaired consciousness and vivid, often frightening, hallucinations. Urinary incontinence occurs not only during sleep, but also during the daytime.
Strong analogue products
Phenzitate, a drug from the same group of tranquilizers, is popular today; there is practically no difference with Phenazepam and, what is important, the drugs have a similar list of contraindications. The product cannot be used in the following cases:
- severe dysfunction of the kidneys and liver;
- myasthenia gravis;
- pregnancy;
- poisoning – sleeping pills, ethyl alcohol, narcotic drugs, other tranquilizers.
Elderly people should be especially careful when taking the drug.
In cases where insomnia is assessed as very severe, they resort to stronger drugs than Melaxen. Today, drug treatment regimens are widely used, which are based on modern non-benzodiazepine drugs, which are relatively safe. These are 3rd generation hypnotics, Z-group. Among them we will name:
- Zopiclone;
- Zolpidem (Sanval);
- Zaleplon (Andante).
They are often used to treat chronic insomnia, when the cause may be hidden either in a primary sleep disorder, or in pathologies of a mental or somatic nature. The above drugs are available only with a prescription.
Compatibility of Phenazepam with other drugs
Phenazepam is one of the most potent tranquilizers that cannot be combined not only with alcoholic beverages, but also with many other medications. These include:
- sleeping pills;
- anticonvulsants;
- sedatives;
- tranquilizing.
Phenazepam and Corvalol, the compatibility of which is considered unacceptable, are strictly prohibited from being taken together. Corvalol contains ethyl alcohol and the tranquilising substance phenobarbital - which is why simultaneous use with Phenazepam causes an overdose of tranquilizers with the most severe consequences.
The drug should not be taken together with antiparkinsonian drugs, since Phenazepam significantly reduces their effectiveness.
When treating arterial hypertension, it must be taken into account that the tranquilizer increases the effect of antihypertensive medications. In such cases, it is necessary to reduce their dosage.
Also, Phenazepam tablets should not be combined with Clozapine and other antipsychotics. This drug combination often causes depression of breathing and the respiratory center.
Domestic analogues
Let's go through domestic drugs, as well as their prices.
First on the list we’ll put Phenorelaxan, a drug produced by Moskhimfarmpreparaty. Available in tablets. Price per package (also 50 pcs.) - 79 rubles. Interestingly, this drug is practically no different from Phenazepam.
The next domestic analogue is Fenzitate, which is produced by the company Tatkhimfarmpreparaty. A similar package costs 86 rubles, that is, slightly cheaper than Phenazepam.
And the third drug in a row produced in Russia is Elzepam (). Cost for 50 pcs. — 87 rub.
Cost of medicines
The cost of Phenozepam is in the middle price segment. Domestic analogs are at the same level as Phenazepam or cheaper, foreign substitutes are several times more expensive than the original product.
Name of the drug | Dosage of the active ingredient in mg | Number of pieces per package | average price |
Phenazepam | 25 | 50 | 177-193 |
Tranquesipam | 1 | 50 | 98-115 |
Elzepam | 1 | 50 | 97-113 |
Fesipam | 1 | 50 | 119-130 |
Sonapax | 10 | 60 | 290-330 |
Alprazolam | 1 1 | 50 20 | 702-725 301-306 |
Gidazepam | 50 | 10 | 93-111 |
Relanium | 10 | 2 ml/10 | 191-226 |
Etaperazine | 4 10 | 50 50 | 346-455 389-400 |
Adaptol | 300 500 | 20 20 | 1038-1048 1601-1612 |
Amitriptyline | 25 10 | 50 2 ml/10 | 29-77 52-90 |
Bellataminal | 3 | 30 | 132-147 |
Glycine | 300 | 20 | 178-201 |
How is it with them and how is it with us?
Doctors are very careful when treating patients with Phenazepam. In addition to the fact that the drug gives a certain result in the treatment of such ailments as epilepsy, insomnia, anxiety and depression, alcohol withdrawal, it potentially causes a whole list of side effects.
Doctors especially focus on stopping the drug. This should be done very carefully and gradually. And under no circumstances should you try to do this yourself. If your appointment is nearing the end, you should consult a doctor.
Very often, doctors prescribe drug withdrawal in a hospital in order to monitor the patient. For those people who do not like to follow doctors' instructions, this is important.
If we compare treatment methods, in the West they refuse drugs that have a strong effect, like Phenazepam. They resort to analogues, which have a milder effect, but often provide a longer lasting effect.
If you go for a consultation with a doctor, and he does not prescribe you Phenazepam, but an analogue from the group of over-the-counter drugs, then this is a clear sign that he treats according to European standards.
Experts note the harmfulness of all tranquilizers without exception. When resorting to Phenazepam, it should be remembered that it was developed back in the seventies, and then was intended only for military purposes. Later he entered civilian production. Today there is a strong tendency to abandon therapy with this drug in favor of its analogues.
Over-the-counter similar products
There are over-the-counter analogues of Phenazepam on the pharmacological market. These medications have a similar therapeutic direction to Phenazepam, but have minimal toxic effects on the patient’s body.
Etaperazine
Etaperazine is an antipsychotic and is prepared in tablets based on the component perphenazine. The medication is available for free sale in pharmacy kiosks.
Medicine is prescribed for:
- psychomotor disorders with hyperactivity;
- nervous overexcitation;
- schizophrenia;
- symptoms of fears, anxiety, phobias and paranoia;
- allergic itching.
It is contraindicated to prescribe the medicine for:
- cirrhosis, jaundice and hepatitis;
- nephritis and myxedema;
- impaired hemostasis;
- systemic pathologies of the brain;
- heart failure in decompensated form;
- thromboembolism;
- allergies to perphenazine.
The medicine is not used in the treatment of children under 12 years of age, during lactation and pregnancy.
Daily dose – 4-80 mg. In acute pathologies and resistant attacks, the dosage is increased to 150-400 mg per day. The doctor prescribes the dosage regimen individually for each patient.
Side effects:
- dyspepsia and cholestatic jaundice;
- parkinsonism, akathisia and somnolence;
- agranulocytosis and anemia;
- contact dermatitis with rash and itching.
Amitriptyline
Amitriptyline is produced in parenteral solution and tablets with the main ingredient - amitriptyline hydrochloride.
A neuroleptic is prescribed for:
- depressions of various types and genesis;
- psychopathic pathologies in children with sleep rhythm disturbances (insomnia), agitation and severe anxiety;
- schizophrenia and mixed type psychoses;
- behavioral deviations;
- alcohol withdrawal symptoms;
- bulimia and enuresis of neurological etiology;
- migraine;
- ulcerative destruction in the gastrointestinal tract.
Medicine is not prescribed for:
- sensitivity to the drug composition;
- alcohol intoxication, as well as poisoning with narcotic and pharmaceutical drugs;
- myocardial infarction and severe cardiac pathologies;
- glaucoma;
- therapy with MAO inhibitors.
It is also not prescribed in pediatrics to children under 6 years of age. During lactation, taking the medication is strictly prohibited due to the penetration of components into breast milk.
Amitriptyline is prescribed with restrictions for:
- high intraocular pressure;
- asthma of bronchial etiology;
- cardiac and systemic disorders;
- liver failure and kidney dysfunction;
- thyrotoxicosis and hypotension of the bladder.
During pregnancy, the drug is prescribed as a last resort and for vital signs. Neurological and depressive conditions begin to be treated with a dosage of 25-50 mg, followed by an increase to 300 mg. After achieving a therapeutic effect, the dosage should be gradually reduced. Children 6-12 years old are prescribed 10-30 mg per day, and after 12 years old - 100 mg.
Negative effects:
- dyspepsia;
- increased intraocular pressure and blurred vision;
- mydriasis and confusion;
- obstruction in the intestines;
- heart rhythm disturbance.
Glycine
Aminoacetic acid is the main ingredient in Glycine sublingual tablets. Absorbable tablets are prescribed for:
- decreased memory, attention and concentration;
- children's restlessness and hyperactivity;
- mental and emotional stress;
- deviant behavior in adolescents;
- mental lability;
- encephalopathy or brain injury;
- impaired microcirculation in the brain and spinal cord.
Glycine is not prescribed for lactation and allergies to the ingredients in the composition.
The tablets need to be dissolved under the tongue or between the cheek and gum. The average dosage is 100 mg, 3 doses per day for 15-30 days. For injuries of the brain and the periphery of the central nervous system, patients are prescribed 50 mg 3 times a day from 3 years of age for a week or two, and then 50 mg once a day for a month.
Negative symptoms:
- bronchospasms, allergic rhinitis and shortness of breath;
- skin itching, hyperemia and urticaria;
- dyspepsia.
Adaptol
Adaptol is a neuroleptic with an anticonvulsant effect with the active component mebicar. The medicine is produced in tablets and prescribed for:
- neuroses;
- symptom of fear;
- apathetic moods;
- feelings of restlessness and anxiety;
- chest pain of non-cardiological etiology;
- depression and severe stressful situations;
- PMS and menopause;
- giving up nicotine.
It is strictly forbidden to take in pediatric practice, women during pregnancy and during breastfeeding.
When treating psychoneurotic diseases, the starting dosage is 300-500 mg with a gradual increase to 3 g. The medicine should be taken three times a day.
Side effects:
- dyspepsia;
- urticaria and bronchospasms, Quincke's edema;
- dizziness, severe pain in the head in different locations and increased drowsiness.
Bellataminal
Bellataminal is produced in tablets based on ergotamine, belladonna and phenobarbital. This combined antipsychotic is prescribed for:
- insomnia;
- increased irritation, nervousness;
- menstrual cycle disorders of neurotic etiology;
- neurodermatitis (reduction of itching);
- vegetative-vascular dystonia.
Bellataminal is not prescribed for:
- sensitivity to the drug composition;
- unstable angina and manifestations of systemic atherosclerosis;
- impaired impulse conduction through the myocardium and arrhythmia;
- spasm of arteries in the periphery of the bloodstream;
- glaucoma;
- pregnancy and breastfeeding.
Tablets are taken orally after eating, 1 tablet 2-3 times a day. The therapeutic course lasts 2-4 weeks. If necessary, you can repeat the course in a month.
Side symptoms:
- dyspepsia and dry mouth;
- allergies to the epidermis - itching, rash, hyperemia and urticaria;
- bronchospasms, rhinitis;
- paresis and dizziness;
- drowsiness and lethargy;
- urinary disorders;
- pressure fluctuations and myocardial rhythm disturbances.
And again about the shortcomings
The effect of the drug on the body is very ambiguous; it has a considerable list of both contraindications and side effects.
In addition to traditional hypersensitivity, pregnancy, breastfeeding, adolescence and childhood, there are also specific contraindications.
Medicines should not be used in a state of shock or coma, severe depression (when suicidal tendencies occur), angle-closure glaucoma, myasthenia gravis, severe chronic obstructive pulmonary disease, and severe alcohol or sleeping pill poisoning.
Among the side effects, first let’s say a few words about the effect on the central and peripheral nervous system. At the beginning of drug therapy, drowsiness is observed, especially in elderly people. In addition, during the same period, ataxia, a feeling of fatigue, dizziness, confusion, gait instability, slowed mental and motor reactions, disorientation, and decreased ability to concentrate develop.
Very rarely there are reactions that contradict the effect that the drug should have. We are talking about the development of fear, anxiety, muscle spasms after using the medicine.
Compatibility of Phenazepam with alcohol
Many patients are interested in whether it is possible to take Phenazepam and alcohol at the same time - the consequences of such a combination can be life-threatening. The compatibility of a tranquilizer with alcohol is unacceptable, since ethyl alcohol significantly enhances the effect of the drug. This leads to severe intoxication of the body.
The action of the pharmacological agent is aimed at suppressing the increased excitability of the central nervous system, while at the same time alcohol has an stimulating effect. Taking a tranquilizing drug after drinking alcohol causes the so-called phenazepamine sleep - a dangerous condition in which the functioning of almost all internal organs and systems is inhibited.
In medical practice, there are cases where phenazepam sleep ended in cardiac arrest.
The simultaneous use of Phenazepam with alcoholic beverages increases the side effects of the pharmaceutical drug.
This combination causes severe vomiting mixed with blood, alcohol-induced confusion, attacks of uncontrollable aggression, disorientation in space, deterioration of thinking and the appearance of suicidal tendencies.