The drug has several pharmaceutical forms for systemic and local use, helps restore the integrity of tissues in case of damage, eliminates the consequences of acute intoxication, infectious processes and inflammation. Methyluracil has multidirectional therapeutic effects and should be kept in your home medicine cabinet.
Indications and contraindications for use
The essence of the medicinal effect of methyluracil suppositories is explained by the fact that the active substances contribute to the production of leukopoiesis
.
It is these components that accelerate the formation of red blood cells
and
leukocytes
necessary for accelerated healing.
Candles are produced in the form of a dense creamy mass of a whitish-yellow hue.
| Indications for use | Contraindications |
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Side effects are extremely rare when using methyluracil suppositories. If administered too frequently, a person may experience headaches, severe dizziness, nausea, vomiting, an allergic reaction, burning and itching in the injection area. If you experience any of these symptoms, stop use immediately.
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Methyluracil suppositories (supp. rect. 500 mg No. 10)
A country
Russia
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Active substance
Dioxomethyltetrahydropyrimidine + Sulfadimethoxine + Trimecaine + Chloramphenicol
Compound
1 suppository contains: methyluracil 500 mg
pharmachologic effect
Immunostimulant, dioxomethyltetrahydropyrimidine. Helps normalize the metabolism of nucleic acids, accelerates the processes of cellular regeneration in wounds, accelerates the growth and granulation maturation of tissue and epithelization (including in rapidly proliferating cells of the gastrointestinal mucosa), stimulates erythro- and leukopoiesis, cellular and humoral immunity factors. Has anabolic activity and anti-inflammatory effect. When used externally, it also has a photoprotective effect.
Indications for use
For oral administration: leukopenia (mild forms, including those resulting from chemotherapy of malignant neoplasms, during X-ray and radiation therapy), agranulocytic tonsillitis, alimentary-toxic aleukia, anemia, thrombocytopenia, benzene intoxication, radiation sickness, convalescence (after severe infections), peptic ulcer of the stomach and duodenum, slow-healing wounds, burns, bone fractures, hepatitis, pancreatitis. For external use: slow-healing wounds, burns, bone fractures, photodermatitis; trophic ulcers, bedsores, deep wounds. For topical use: proctitis, sigmoiditis, ulcerative colitis.
Mode of application
Orally, during or after meals, 500 mg 4 times a day (if necessary, up to 6 times a day); children from 3 to 8 years old - 250 mg, over 8 years old - 250-500 mg 3 times a day. The course for diseases of the gastrointestinal tract is 30-40 days; in other cases it may be shorter. For external use, the dosage regimen is set individually, depending on the dosage form used. The frequency of changing dressings depends on the depth and area of the wound surface, the intensity of exudation and the presence of necrotic masses. Used rectally in adults, 0.5-1 g 3-4 times a day; for children aged 3-8 years - 250 mg/day, for children aged 8-15 years - 500 mg/day. The course of treatment is from 1 week. up to 4 months
Interaction
With simultaneous therapy with systemic antibacterial drugs, a synergistic effect is observed.
Side effect
Possible: allergic reactions; when taken orally - headache, dizziness, heartburn.
Contraindications
Hypersensitivity to methyluracil. For oral administration: leukemia (leukemic forms, especially myeloid), lymphogranulomatosis, hemoblastosis, malignant bone marrow diseases. For external and local use: excessive granulation in the wound.
Overdose
No cases have been recorded. When used correctly, overdose is impossible.
special instructions
Dosage forms of methyluracil should be used strictly according to the appropriate indications.
Storage conditions
Room temperature
Who is prescribed suppositories?
According to doctors' reviews and instructions, suppositories with Methyluracil belong to the group of regenerating drugs. Thus, this drug has a pronounced healing, antiseptic and analgesic therapeutic effect. Immediately after penetration into the mucous membrane, the medicine enhances the process of cell division, thereby achieving a pronounced regenerating effect.
Methyluracil suppositories, the indications for use of which are described in the instructions for the drug, can be used to treat various proctological problems.
At the same time, these suppositories will be effective and will have a pronounced therapeutic effect in both acute and chronic diseases in humans. Unlike ointments, Methyluracil suppositories, whose indications for use are quite varied, can be used in the following cases. Methyluracil suppositories indications for use:
- Exacerbation of chronic hemorrhoids.
- Anal fissures.
- Mechanical damage to the rectum, which can occur during anal sex, an enema, colon surgery, or an incorrect diagnostic procedure.
- Inflammation of the rectum that occurs after prolonged constipation and indigestion.
- Exacerbation of hemorrhoids after the birth of a child.
Inflammation of the rectum caused by bad habits or poor nutrition. Methyluracil suppositories quite quickly reduce pain in a person, thereby returning the patient to a normal routine of life. Indications for the use of these suppositories can be described in more detail by your attending physician. This drug can be used only after the permission of the observing proctologist, because the wrong dosage of the drug can lead to the development of a number of side effects.
Use in gynecology
Methyluracil suppositories have gained enormous popularity in gynecology. They are used both for the treatment and prevention of serious diseases in women. Suppositories can be used both vaginally and rectally.
The essence of the positive effect lies in a large dose of methyluracil
.
Also, in addition to it, the composition contains a large amount of paraffin
and
macrogol
.
It is strictly forbidden to administer methyluracil suppositories during menstruation - even more bleeding may occur and severe pain will appear.
Remember that the attending physician must supervise such therapy. Only he will be able to determine the most appropriate dose, as well as the duration of treatment. It is best to douche before inserting a suppository to clear the vagina of ridges.
To do this, you can use a weak solution of baking soda and sea salt. The effectiveness of such therapy is confirmed by numerous reviews that you can easily find on the Internet.
Treatment of erosion
Typically, methyluracil suppositories are used for more effective and rapid treatment of cervical erosion
. The fact is that the active components of the drug are able to heal open wounds. To get rid of this disease, you need to administer a suppository every morning and evening.
Usually it takes about 10-14 days
. It is very important that such therapy takes place under the full supervision of a physician. During treatment, you need to take a blood test every 3 days to determine the level of leukocytes and red blood cells.
This medicine is often prescribed for mechanical damage to the vagina and cervix. Doctors often prescribe such vaginal suppositories to women after surgery. This measure helps prevent infectious
and
inflammatory
processes.
Application in proctology
Methyluracil suppositories are actively used in proctology
. With their help, you can easily defeat diseases of the lower intestine and the anus itself. Most often, this remedy is prescribed for the treatment of fissures and hemorrhoids. In some cases, this medicine can be used to treat ulcerative and erosive colitis, damage to the sigmoid and colon.
If during insertion of a suppository into the intestine you feel acute unbearable pain, you should immediately stop the procedure. You may have damaged the walls.
Thanks to the unique composition of the suppositories, they can be used to effectively cope with rectitis and colpitis of the anus. They also quickly relieve inflammation in the rectum.
It is very important that the dose of the active substance is selected exclusively by a doctor. In this matter, it is necessary to assess the age of the patient, as well as the degree of damage. It should be noted that such candles can be used even by children.
Usually, to treat proctological problems, suppositories are inserted into the anus, two pieces 3 times a day for adults, and 1 piece for children once a day. If the child is under 8 years old, then it is permissible to administer only half of it once.
Before starting the procedure, you must thoroughly empty your bowels. To do this, you can do a special cleansing enema. To maximize the effectiveness of this procedure, you need to lie down for several minutes after administration.
Treatment of hemorrhoids
Haemorrhoids
- inflammation of the lower process of the rectum. Typically, this disease occurs in men with a sedentary lifestyle. To get rid of this disease, you need to insert a candle into the anus with your fingers. On average, the duration of therapy is from 1 to 4 weeks.
To administer the medicine as comfortably as possible, it should be done in a comfortable position. Before you begin insertion, wash your hands thoroughly and put on cotton underwear.
Doctors do not recommend using methyluracil suppositories for external hemorrhoids and hemorrhoids.
Carefully and slowly insert the suppository into the anus. Try not to spill anything, as the contents contain all active substances.
In this case, the effectiveness of the procedure will be extremely low. While the candle is in your anus, try not to move.
Because of this, many doctors recommend administering them at night. If this is not possible, then spend at least 30 minutes at rest. Typically, the use of rectal suppositories is due to:
- exacerbation;
- inflammatory process;
- cracks in the anus;
- recovery after surgery.
Using suppositories with methyluracil helps speed up healing after surgery. In addition, they help relieve pain and swelling and speed up recovery. It is permissible to use suppositories up to four times a day, but most often they are administered in the morning and evening before bedtime.
Methyluracil 500 mg
Dosage form
Rectal suppositories
Composition for 1 suppository:
Active substance:
Dioxomethyltetrahydropyrimidine (methyluracil) – 0.5 g
Excipients:
solid fat (vitepsol (brands H 15, W 35), supposir (brands NA 15, NAS 50)) - until a suppository weighing 2.3 g is obtained.
Description
Suppositories are white or white with a yellowish or creamy tint, torpedo-shaped. The appearance of a white coating on the surface of the suppository is allowed. In a longitudinal section - homogeneous, without inclusions, the presence of an air rod or funnel-shaped depression is allowed.
Pharmacotherapeutic group
Tissue repair stimulator.
ATX code:
L03AX.
pharmachologic effect
Has anabolic activity. It has hematopoietic, leukopoietic, immunostimulating, anti-inflammatory effects. By normalizing nucleic acid metabolism, it accelerates the processes of cellular regeneration in wounds, accelerating the growth and granulation maturation of tissue and epithelization (including in rapidly proliferating cells of the mucous membrane of the gastrointestinal tract), stimulates erythro- and leukopoiesis, cellular and humoral immunity factors.
Indications for use
Erosive-ulcerative colitis, proctosigmoiditis, anal fissures.
Contraindications
Hypersensitivity to the components of the drug, leukemia (leukemic forms), lymphogranulomatosis, hemoblastosis, malignant bone marrow diseases, children under 8 years of age.
Use during pregnancy and breastfeeding
No special studies have been conducted regarding the safety of using Methyluracil rectal suppositories in pregnant women and during breastfeeding. The drug is used during pregnancy and breastfeeding only if the expected benefit to the mother outweighs the potential risk to the fetus or child.
Directions for use and doses
Rectally: 0.5-1 g 3-4 times a day, children 8-15 years old - 500 mg per day.
The course of treatment is from 7 days to 4 months, depending on the nature of the disease.
Side effect
Allergic reactions and a short-term mild burning sensation are possible.
Overdose
The drug is for rectal use; no cases of drug overdose have been reported.
Interaction with other drugs
There is no information on interactions with other drugs for rectal use; combined use of the drug with other rectal drugs is not recommended.
special instructions
No information available.
Impact on the ability to drive vehicles and machinery
There is no reason to believe that the use of the drug Methyluracil may affect the ability to drive a car or operate machinery.
Release form
Rectal suppositories, 500 mg.
1, 2, 3, 4, 5, 6, 7, 8, 9, 10 suppositories in blister packs made of two-layer PVC-PE or EP-73S film.
1, 2, 3, 4, 5, 6, 7, 8, 9, 10 blister packs together with instructions for medical use of the drug are placed in a pack of boxed cardboard for consumer packaging or chrome-ersatz.
Storage conditions
In a place protected from light, at a temperature not exceeding 25 oC.
Keep out of the reach of children.
Best before date
2 years.
Do not use after the expiration date stated on the label.
Conditions for dispensing from pharmacies
On prescription.
Indication of special precautions when disposing of unused drugs
No information available.
How to insert Methyluracil suppositories?
In gynecology, if a doctor has prescribed suppositories with methyluracil for vaginal administration, then their use should be stopped during menstrual bleeding. After the end of the discharge, you can continue the course of treatment. However, it is better to start treatment immediately after the critical days have ended. Then you won’t have to take a break if your period suddenly starts.
This exclusion of the use of vaginal suppositories during menstruation is due to the fact that they will dissolve faster in secretions and, accordingly, will be eliminated from the body before their therapeutic effect on the body begins. After the procedure for cauterizing the erosion, the gynecologist may prescribe suppositories with methyluracil. Methyluracil suppositories for erosion can have a local wound-healing, regenerating effect.
Methyluracil suppositories have analogues: Kolertek, metacil, meturacol, stizamet.
It should be remembered that during the period of treatment with methyluracil suppositories it is necessary to completely exclude sexual relations. Methyluracil suppositories are effectively used to treat inflammatory processes in the body of any etiology, including the treatment of diseases of the female organs. However, suppositories with methyluracil have the greatest therapeutic effect as part of complex therapy, whereas when used separately, the therapeutic effect can be quite weak.
Methyluracil in gynecology
Methyluracil suppositories are used in gynecology for the therapeutic treatment of colpitis, vulvoginitis, and vaginal dysbiosis. They are prescribed for erosive damage to the uterine cervix before and after laser coagulation. Dioxomethyltetrahydropyridimine has proven itself in the elimination of tissue damage that appears during labor and surgical amputation of the reproductive organ.
During critical days, the medication should be taken rectally, unless the treatment provides for a break. The released blood fluid will remove the medicine earlier than expected. During therapy, complete sexual rest is required. For girls who are not sexually active, methyluracil suppositories are prescribed only rectally. The therapeutic course lasts from 8 to 16 days.
The treatment time and daily dose of medication are determined individually by the gynecologist.
Suppositories containing methyluracil are allowed during pregnancy and lactation. The drug is not absorbed into the blood and breast milk and does not have a pathological effect on the embryo. Rectal suppositories with methyluracil combine well with other drugs. Clinical trials did not reveal drug antagonism.
It is recommended to prescribe suppositories simultaneously with antibacterial and steroid therapy. You should not use dioxomethyltetrahydropyridimine while taking corticosteroids, in order to avoid reducing the renewing, anti-inflammatory, wound-healing properties of the suppository.
How to use Methyluracil
It is recommended to take the medication in tablets after meals: 1 tablet 4–6 times a day. The pills should be swallowed whole with plenty of water. Duration of therapy: up to 40 days. But the final word always remains with the doctor.
Methyluracil suppositories are administered one at a time intravaginally or into the rectum, depending on the type of disease. The number of candles per day ranges from 3 to 8 pieces. Treatment can last up to 3–4 months.
The ointment is applied to damaged, previously washed and cleared of exudate skin twice a day. Single dose: no more than 10 g of the drug. Methyluracil can be used under sterile dressings. Small scratches and abrasions should not be covered after applying the product, so as not to interfere with their granulation. External treatment is continued until wounds or ulcers heal. The ointment can be combined with the use of antibacterial and antiviral drugs.
