We make EPLAN: description, composition, instructions, ointment, solution, for burns and wounds

Among the preparations for external use there are ointments with a wide spectrum of action. An example of such a medicine is Eplan. It is used for wounds, abrasions, bedsores, burns, herpes and many other skin diseases. It has a bactericidal, anti-inflammatory and analgesic effect. You can buy the ointment at an affordable price in almost any pharmacy.

EPLAN THIS

EPLAN is used to treat wounds and skin lesions of any origin, accelerates the healing of skin lesions, reduces the risk of complications, prevents the development of pustular skin lesions, destroys microbes and bacteria, and prevents wound infection. After treatment with EPLAN, wound healing accelerates, because... When the skin is regenerated, secondary infection does not occur, tissue does not die, and a dry scab does not form on the wound. Dressings treated with EPLAN do not stick to the wound.

EPLAN is an antiseptic dermatotropic drug in the form of EPLAN cream ointment, liquid EPLAN solution, disposable wipes, for external use with bactericidal, anti-inflammatory, wound healing, regenerating, detoxifying, antipruritic, analgesic, protective and softening effects.

Composition of EPLAN: triethylene glycol, ethylcarbitol, glycolan, glycerin.

Glycolan enhances the regenerating properties of tissues, ethyl carbitol provides an antibacterial effect, triethylene glycol disinfects and cleanses the wound, glycerin has a softening effect and creates a protective film on the surface of the epithelium. The EPLAN formulation does not use antibiotic or hormonal components.

EPLAN - A UNIVERSAL RESULT FOR WOUNDS OF ANY ORIGIN

Wound healing ointment EPLAN-cream and liquid EPLAN-solution are effective remedies for the treatment of wounds, burns, cuts, abrasions, any diseases and damage to the skin.

SPECIAL FEATURES OF EPLAN TOOLS

First aid

EPLAN is used to provide first aid for various injuries to the skin: all types of burns - solar, thermal, boiling water, radiation, chemical, etc. For first aid against burns, use wound healing ointment EPLAN cream or liquid EPLAN solution.

EPLAN is also recommended for the initial treatment of wounds, frostbite, and skin after exposure to toxins. EPLAN is first aid for wounds, abrasions, and cuts.

Treatment of skin diseases and damage

EPLAN is used to treat skin diseases such as: sun, thermal, chemical burns; frostbite; bruises, wounds, cuts, abrasions, abrasions, cracks; early and late radiation damage to the skin; trophic ulcers and bedsores; psoriasis; pyoderma (staphylococcal and streptococcal), microbial eczema, dyshidrosis complicated by secondary infection; viral infection (herpes, warts, condylomas, papillomas); acne vulgaris; diseases of the nose (boils, sycosis, eczema, burns and traumatic injuries); external and middle ear (otitis, otomycosis, etc.).

EPLAN accelerates the healing of wounds, burns, and any skin damage, and reduces the risk of complications.

Relieving swelling and itching of the skin of various origins

including insect bites (mosquitoes, wasps, bees, etc.);

Protecting the skin from adverse effects

EPLAN is used to protect the skin from the effects of various poisonous and toxic substances. EPLAN is used to protect the skin from petroleum products, varnishes, acids, industrial oils and cutting fluids.

In sports

EPLAN is used in the treatment of sports injuries, bruises, hematomas.

For animals

EPLAN can be used in veterinary medicine for similar skin diseases in animals.

In the troops of the Ministry of Defense

EPLAN is used by the Ministry of Defense of the Russian Federation as an Individual Anti-Chemical Package IPP-11. IPP-11 is intended to neutralize toxic and irritating substances on human skin and personal protective equipment. When applied to the skin in advance, it protects from the effects of chemical warfare agents* for 6 to 24 hours.

GENERAL INFORMATION ABOUT EPLAN

Trade name:
EPLAN
Latin name:
Aplun
ATC classification:
D06 “Antibiotics and antimicrobial agents used in dermatology”
Pharmacological groups:
Dermatotropic agents, Antiseptics and disinfectants, Regenerants and reparants
Nosological classification (ICD-10):
H60 Otitis externa; H62.2 Otitis externa due to mycoses; H65 Non-suppurative otitis media; L00-L08 Infections of the skin and subcutaneous tissue; L02 Skin abscess, boil and carbuncle; L08.0 Pyoderma L30.1 Dyshidrosis [pompholyx]; L30.3 Infectious dermatitis; L30.8 Other specified dermatitis; L58 Radiation radiation dermatitis L70 Acne; L73.8.0* Sycosis L98.4.2* Trophic skin ulcer T14.1 Open wound of an unspecified area of the body T30 Thermal and chemical burns of an unspecified localization W57 Bite or stinging by non-venomous insects and other non-venomous arthropods
Manufacturer:
ZAO “OBERON”, Moscow.
Release forms:
Eplan cream in the form of ointment, liquid Eplan solution, Eplan napkins.
Recommended:
for all age groups.
Contraindications:
has no contraindications (except for individual intolerance to the components of the drug).
Study plan:
Completed research at: - All-Union Burn Center at the Institute of Surgery named after. Vishnevsky; — Moscow Regional Research Clinical Institute named after. Vladimirsky; - 1st City Hospital; — Medical Radiological Center of the Russian Academy of Medical Sciences (Obninsk); — Moscow Regional Oncology Center; — Kiev Research Institute of Pharmacology and Toxicology.
Eplan storage:
Does not require special storage conditions. Shelf life: 5 years.

EPLAN BUY

Eplan can be purchased at your nearest pharmacy at an affordable price, or in specialized online stores selling medicines. Eplan is dispensed without a doctor's prescription (medicines should be prescribed only by the attending physician, taking into account the patient's medical history and diagnostic results).

HISTORY OF EPLAN

At the end of the 70s in the USSR, it was decided to create a special drug for the prevention of skin-resorptive and inhalation skin lesions from highly toxic chemical warfare agents. One of the requirements for the drug was that it should not have an irritating effect and not disrupt the barrier functions of the skin.

The drug was created on the basis of salts of rare earth elements and polyhydroxy compounds. During military trials, a positive effect of the drug on the course of various skin diseases was revealed. This marked the beginning of large-scale research into the possibilities of formulating the drug for civilian use. The drug was given the trade name "EPLAN".

LANTHANUM. INFLUENCE OF LANTANOIDS ON BIOLOGICAL PROCESSES

The therapeutic effect of EPLAN in the forms of wound healing agents for burns, wounds, cuts and abrasions - liquid EPLAN solution and EPLAN cream ointment, is undoubtedly associated with the presence of lanthanum in the formulation. Lanthanum is one of the representatives of the family of rare earth metals (lanthanides). Some lanthanides, including lanthanum, are found in the human body. A small amount of them was found in the spleen, very small amounts (0.1 mg/kg) - in dentin and tooth enamel. From the limited data it does not follow that lanthanides are necessary for the normal functioning of the body, but their ability to influence biological processes is beyond doubt

. Being good complexing agents, they are able to form complexes with many organic ligands (carbohydrates, amino acids, hydroxy acids, nucleotides, phosphatides, vitamins). The effect of lanthanides on biochemical functions is associated with their ability to replace Ca2+ in biological systems. The presence of f-electrons in the electronic shells of their atoms has a certain influence on the biological properties of lanthanides due to the effect of the magnetic microfields caused by them. This explains the ability of lanthanides to increase the phagocytic activity of blood leukocytes.

The use of lanthanides in medicine is primarily associated with their anticoagulant properties. They affect various stages of the blood coagulation process: they inhibit the synthesis of prothrombin, have antagonistic properties against thrombin, act as Ca2+ antimetabolites, displacing it from systems with one or more protein coagulation factors; via mast cells, they increase the level of free heparin in the blood when administered in sufficiently large doses.

The anti-inflammatory effect of lanthanide ions has been described, which have a high affinity for phospholipids and “stabilize” cell membranes by blocking ion channels; this effect of lanthanides on the site of inflammation is similar to the effect of corticosteroids.

You can buy EPLAN in all pharmacies in Russia. EPLAN is one of the most affordable drugs on the Russian market for wound healing products for wounds, cuts, and abrasions, intended both to protect the skin and to treat it.

* Chemical warfare agents

- chemical compounds that are the basis of chemical weapons. They have certain toxic and physico-chemical properties, which, when used in combat, ensure the defeat of enemy personnel, contamination of the air, military equipment and terrain. Chemical warfare agents are part of chemical weapons: shells, mines, missile warheads, aircraft bombs, aircraft jets, smoke bombs, grenades.

Chemical warfare agents penetrate the human body through the skin, wounds from chemical weapons fragments, and the respiratory system and, as a result, cause damage to the body. Lesions can also occur as a result of eating contaminated food and water.

The toxicity of chemical warfare agents is the ability to have a damaging effect on the body. Toxicity (local or general) manifests itself when a chemical warfare agent comes into contact with the body, causing a damaging effect:

1. Local damage manifests itself at the site of contact with body tissues (damage to the skin, irritation of the respiratory system, visual impairment).

2. General damage occurs as a result of chemical warfare agents entering the blood through the skin (skin-resorptive toxicity) or through the respiratory system (inhalation toxicity).

EPLAN: PHARMACOLOGICAL ACTION

BACTERICIDAL AND ANTI-INFLAMMATORY ACTION

Wounds that occur as a result of skin damage (especially wounds of mechanical origin) are primarily infected - pathogenic bacteria enter the wound. Without proper initial treatment of the wound, its infectious contamination (contamination) may increase. However, it is necessary to protect the wound not only when it occurs, but also during its healing, because it can become secondarily infected, which will lead to pain in the wound, its re-infection and inflammation will occur.

EPLAN wound healing agent destroys most bacteria and germs. This is facilitated by the components of the drug: Glycolan, Elitcarbitol, Triethylene glycol.

Phagocytes are cells that protect the body from the development of infection. Glycolan, being a lanthanide, has high antimicrobial activity and increases the phagocytic activity of blood leukocytes (phagocytes capture and destroy pathogens of infectious diseases, releasing a substance that damages bacteria and fungi, increasing the flow of immune cells to the site of inflammation). This leads to rapid cleansing of the wound and eliminates the growth of pathogenic bacteria and fungi in the wound and on the surface of the skin around the wound.

Ethylcarbitol has a disinfecting and antimicrobial effect and enhances the effect of Glycolan. As a result of healing with EPLAN ointment cream or liquid EPLAN solution, secondary infection of the wound is prevented, the healing process occurs quickly and without complications.

Triethylene glycol disinfects the wound and enhances the protective properties of the treated wound.

WOUND HEALING AND REGENERATING EFFECT

EPLAN is a catalyst for skin regeneration. The effect of EPLAN as a drug for regeneration, skin restoration, rapid healing of wounds and burns is due to the presence of lanthanide (Glycolan) in its composition. Glycolan influences the process of proliferation of damaged cells.

The use of EPLAN ointment cream or liquid EPLAN solution on a burn or wound triggers the process of lanthanides acting on the membranes of proliferating skin cells, which leads to stimulation of their cell division and rapid healing of the wound.

DETOXIFICATION EFFECT

Sometimes during the healing of wounds (for example, burns), intoxication of the patient’s wound occurs, as a result of which toxins, under-oxidized compounds, bacterial tissue, and dead tissue appear in the wound. As a result, signs of toxic damage to the victim appear. Glycolan, which is part of EPLAN, enhances the phagocytosis of blood cells and tissues: blood leukocytes actively destroy pathogenic bacteria and dead cells, preventing the entry of decay products of necrotic tissues and bacteria into the patient’s blood through the wound. This leads to active detoxification of the wound and the patient’s body.

Moreover, EPLAN itself is non-toxic and does not contain hormonal components.

Particularly noteworthy is the importance of detoxifying wounds and skin in case of large wound surfaces, chemical burns, damage from poisonous and toxic chemicals and insect bites, in the prevention of household infections, and in protecting the skin at home and at work.

ANTIPRITIC AND ANALESTIC EFFECT

Treatment of wounds with EPLAN has a local anesthetic effect and eliminates skin itching. This is due to the presence of a thin layer of the drug on the wound surface, which protects the sensitive nerve endings of the underlying tissues from irritation.

In addition, Glycolan, which is part of EPLAN, actively detoxifies the wound, Ethylcarbitol disinfects, and Triethylene glycol disinfects the wound and enhances the protective properties of the treated wound.

PROTECTIVE ACTION

When EPLAN is applied to intact skin, it penetrates the upper layers of the epidermis and fills the intercellular space. This allows you to create a protective preventative barrier coating that is effective for up to 8 hours. A kind of “biological glove” allows you to protect your skin from exposure to various poisonous and toxic substances in everyday life and at work. EPLAN is used to protect the skin from petroleum products, varnishes, acids, industrial oils and cutting fluids.

EPLAN, when applied to intact skin, does not penetrate into the deep layers of the epidermis and does not affect the natural proliferation of Epidermal cells, does not change the water-lipid balance of the skin.

SOFTENING EFFECT

EPLAN contains Glycerin, which retains moisture in the skin and saturates the epidermis with moisture. Glycerin creates a protective film on the wound and on the surface of the skin, which does not impede the flow of oxygen into the wound, prevents it from drying out and the formation of a dry scab. In addition, the access of oxygen to the wound makes it possible to maintain the phagocytic activity of blood cells and tissues increased by Eplan (phagocytosis can only occur in the presence of oxygen in the wound), which leads to its rapid healing.

The softening effect of EPLAN ointment cream or liquid EPLAN solution for burns can reduce pain and the development of the inflammatory process during healing.

special instructions

"Epalan" can be used at any stage of pregnancy, as well as during breastfeeding. It is non-toxic and does not pose a health threat, so it can be used without first consulting a doctor. The only exception is the possible manifestation of allergic reactions due to individual intolerance.

The ointment does not leave greasy marks on clothes, so it can be used to treat different areas. Moreover, due to the presence of glycerin, hands may be “greasy” after treatment. Therefore, it is better to do the procedure at home, before starting work.

EPLAN: OFFICIAL INSTRUCTIONS FOR USE OF THE DRUG

PREPARATION FORM: EPLAN cream, EPLAN solution. GOST 31679-2012

Completed research at the All-Union Burn Center at the Institute of Surgery named after. Vishnevsky, Moscow Regional Research Clinical Institute named after. Vladimirsky, 1st City Hospital, Medical Radiological Center of the Russian Academy of Medical Sciences (Obninsk), Moscow Regional Oncology Dispensary, Kiev Research Institute of Pharmacology and Toxicology.

The drug has simultaneously effective wound healing, regenerating, bactericidal, analgesic, protective and softening effects. Prevents infection, accelerates the healing of wounds, thermal and chemical burns, and pustular skin lesions.

Made on the basis of lanthanum salt and polyhydroxy compounds without the use of antibiotics, hormonal and analgesic agents.

Indications for use

solar, thermal, chemical burns and frostbite, bruises, wounds, cuts, abrasions, abrasions, cracks;
early and late radiation damage to the skin;
trophic ulcers and bedsores;
psoriasis;
pyoderma (staphylococcal and streptococcal), microbial eczema, dyshidrosis complicated by secondary infection;
viral infection (herpes, warts, candilomas, papillomas);
acne vulgaris;
diseases of the nose (boils, sycosis, eczema, burns and traumatic injuries), external and middle ear (otitis media, otomycosis, etc.);
relieving swelling and itching of the skin of various origins, including insect bites (mosquitoes, wasps, bees, etc.);
preventive protection of the skin from exposure to chemicals and aggressive environments (including detergents, fertilizers, solvents, etc.);

Eplan is effective for similar diseases in domestic animals.

Recommendations for use

Burns, small wounds, bruises, abrasions and other skin damage: lubricate the affected area and, as it absorbs and dries, the treatment is periodically repeated until complete healing (for bruises, it is preferable to use cream).

In case of significant damage (purulent wounds, ulcers, bedsores, burns, frostbite): apply a sterile gauze pad soaked in the drug to the damaged surface and fix it with a light bandage. The wound is treated daily or every other day.

For pustular skin diseases, the drug (in liquid form) is applied to previously cleansed skin. Treatment is carried out regularly until the skin is completely normalized. The effect is achieved after 1-4 weeks with regular use.

To protect the skin from sunburn, frostbite, chapping: 15-20 minutes before contact with the irritant, treat exposed skin with the solution.

Preventive protection of the skin from chemicals: the cream is evenly applied to the surface of the skin. A single prophylactic dose of the drug involves treating hands with a consumption rate of 0.2 g/dm. The optimal effect is achieved when using the product twice a day - before and after work. The protective effect is created immediately after application and lasts for a long time.

Side effects

Not identified. Eplan is non-toxic and has no contraindications for repeated and long-term use. No allergic reactions were noted.

Contraindications

Hypersensitivity to individual components of the drug.

Release form and storage conditions

Eplan is available in liquid form in a sealed plastic dropper bottle of 20 g, in the form of a cream in a tube of 30 g. It does not require special storage conditions. Shelf life: 5 years.

. Russia, Moscow, Entuziastov highway, 56.

PREPARATION FORM: EPLAN 25% UREA, GOST 31679-2012

A combined preparation for daily preventive care for dry, rough, cracked skin of the hands and feet. An effective remedy for removing corns, softening dry calluses, hard and difficult to remove cuticles.

Returns skin softness, elasticity, prevents the development of cracks. Reliably protects the skin from damaging factors.

The introduction of one of the strongest keratolytics and moisturizers - urea - into Eplan allows you to fully restore the elasticity of the skin, normalize its moisture and maintain the integrity of the skin. The drug is an effective means of preventing cracks and correcting their manifestations. Suitable for use in hardware pedicure and non-hardware professional foot care programs.

Compound

Triethylene glycol, urea, ethoxydiglycol, glycolan, glycerin, lactic acid, panthenol, perfume.

Recommendations for use

Distribute a small amount of product evenly over cleansed skin.

Contraindications

Hypersensitivity to individual components of the drug.

Storage conditions

Does not require special storage conditions. Keep out of the reach of children.

Best before date

5 years from the date of manufacture.

, Russia, 111123, Moscow, Entuziastov highway, 56.

PREPARATION FORM: Antiseptic, sterile wipes “Eplan from 100 wounds”, RU MZ and SR No. ФСR2009/05127

Purpose

Antiseptic napkins, sterile “Eplan from 100 wounds” - a medical product for external use /hereinafter napkins (bandages) “Eplan from 100 wounds”.

The medical product is a two-layer medical gauze napkin measuring 16x14 cm, impregnated with a solution of the Eplan drug in individual sealed packaging. The product is sterile.

Providing first aid, treatment and treatment of wounds, burns of I, II, III degrees, abrasions, bruises, other traumatic injuries to the skin, purulent-inflammatory diseases of the skin and subcutaneous tissue of various locations and etiologies in all phases of the wound process. Effective prevention of secondary infection.

Providing medical care for combined injuries of a mechanical, thermal, chemical, radiation nature, microbial contamination. “Eplan from 100 wounds” dressings simultaneously have a pronounced antimicrobial (bactericidal, bacteriostatic), wound healing, regenerating, local anesthetic and protective effect.

Evidence base

Approbation is confirmed by approved documents - reports on randomized controlled trials conducted on the basis of: Federal State Institution Institute of Surgery named after A.V. Vishnevsky (Moscow, 2005, 19 p.), Research Institute of Emergency Medicine named after N.V. Sklifosovsky (Moscow , 2005, 15 p.); GOUVPO "Russian State Medical University" (Moscow, 2005, 17 p.); GVKG named after N.N. Burdenko of the Ministry of Defense of the Russian Federation (Moscow, 2005, 7 p.).

The given results are confirmed by medical practice of using the drug, a set of tests carried out on the basis of: GOUVPO VMA named after S.M. Kirov, (St. Petersburg); Federal State Institution “All-Russian Center for Disaster Medicine “Zashchita” (Moscow); State Central Airmobile Rescue Squad of the Ministry of Emergency Situations of Russia (Zhukovsky); /Special unit of the Ministry of Internal Affairs of Russia; Polyclinic No. 5 of the Federal Security Service of the Russian Federation; State Military Clinical Hospital named after N.N. Burdenko of the Ministry of Defense of the Russian Federation (radiological center); City Clinical Hospital No. 15; City Clinical Hospital No. 29; MONIKI; KVD No. 8; KVD No. 19/ (Moscow); Medical Radiological Research Center of the Russian Academy of Medical Sciences (Obninsk); Moscow Regional Oncology Dispensary (Balashikha); GOUVPO Moscow State Medical and Dental University; OJSC NPK Uralvagonzavod (Nizhny Tagil); enterprises: EvrazHolding LLC, Rosatom State Corporation, MOESK, etc.

Indications for use

Providing first aid and treatment of superficial solar, thermal, chemical burns and frostbite; light, superficial bruises, wounds, cuts, abrasions, abrasions, cracks and injuries to the feet.
Treatment of wounds of various locations and etiologies in all phases of healing.
Treatment of purulent-necrotic wounds of soft tissues, incl. post-traumatic, post-operative.
Treatment of trophic ulcers, bedsores and flaccid granulating wounds.

In addition, the drug is indicated

when providing medical care at extreme temperatures (use temperature from -40C to +50C);
in cases of intolerance to drugs (levomekol, levosin, etc.);
to relieve pain and swelling from injuries (bruises, sprains, etc.);
to relieve itching from insect bites;
for skin diseases: dermatitis of various etiologies, acne vulgaris, microbial eczema, viral infections (herpes, warts, condylomas);
for aseptic treatment of skin, destruction of vegetative microorganisms, including fungi;
to protect the skin from unfavorable climatic conditions (low temperatures, wind, humidity) in order to prevent frostbite, chapping and roughening of the skin;
to protect the skin from aggressive chemical and toxic substances (acids, alkalis, fuels and lubricants, rocket fuel, etc.) and to treat skin damage resulting from contact with these substances.

Efficiency

-Reducing the time of outpatient and hospital treatment. The length of hospital stay is reduced: for purulent-necrotic wounds by an average of 5-7 days; for superficial burns of II, III degrees on average for 5-6 days compared to the use of standard traditional medications.

-Reducing the time of outpatient and inpatient treatment compared to modern anti-burn drugs by 3-4 days.

-Reducing the time required for recovery and return to work (to work) of victims after injuries and wounds, reducing treatment costs (see healing time above).

-Reducing the time to provide assistance to victims, saving dressing material due to the compactness, simplicity and ease of use of the dressing, its good fixation on the wound surface of any configuration.

- Absence of allergic reactions, side effects and complications, non-traumatic, pain and swelling relief from injuries.

Procedure for working with the product

Preparing for work

-Open the package (package) along the notch and take out a napkin; -If necessary, unfold the napkin.

Instructions for use

Externally.

-I and II degree burns, small wounds, minor wounds, superficial bruises, cuts, abrasions, abrasions, cracks and damage to the feet and other skin lesions: lubricate the affected area, and repeat the treatment periodically until complete healing.

In case of significant damage.

-Burns with an area of up to 10% at all phases of the wound process: after opening the burn blisters, removing exfoliated necrotic epidermis and treating the wounds with antiseptics (Eplan from 100 wounds napkin), an “Eplan from 100 wounds” napkin is applied to the damaged surface, and a sterile napkin is placed on top and fixed with a gauze bandage (standard dressing). -During the first days of treatment, the dressings are changed daily. In subsequent periods, depending on the condition of the wound, the dressings are changed daily or every 1 day. - Purulent-necrotic wounds, bedsores, etc. at all phases of the wound process: after treating the wound with antiseptic solutions (Eplan from 100 wounds napkin), an Eplan from 100 wounds napkin is applied to the damaged surface and fixed with a light bandage (gauze bandage, IPP1, etc.). Treatment is carried out daily or every other day, depending on the condition of the wound.

Note:

1) In the absence of antiseptics, the wound is treated with an “Eplan from 100 wounds” napkin.

2) If necessary, use (apply to the wound) several “Eplan from 100 wounds” napkins.

3) “Eplan from 100 wounds” dressings are atraumatic and do not stick to wounds when changing dressings.

-In case of chemical burns: in case of contact with vapors, aerosols, solid and liquid chemical ecotoxicants (for example, in field conditions: the poisonous hogweed plant). -If possible, wash off the toxic substance with water and blot the wound with a gauze napkin (bandage or other available material), treat the affected area with an “Eplan from 100 wounds” napkin. An “Eplan from 100 wounds” napkin is applied to the damaged surface and secured with a light bandage. Treatment is carried out daily or every other day, depending on the condition of the wound. -Protection of the skin from adverse climatic conditions; for chemical and sunburn: apply a thin layer of the “Eplan from 100 wounds” napkin to exposed skin (face, hands). - Removing swelling and itching of the skin from insect bites (mosquitoes, wasps, bees): with an “Eplan from 100 wounds” napkin, lubricate (dab) the bite site. -Sprains and inflammation of ligaments: apply an “Eplan from 100 wounds” napkin to the damaged surface and secure it with a light bandage. Change dressings daily or every other day depending on the condition of the wound. -Pustular diseases, acne vulgaris, etc.: treat the damaged surface with an “Eplan from 100 wounds” napkin. Repeat the treatment periodically until complete healing. If necessary, cut the napkin into pieces and sequentially (daily or every other day) apply them to the wound and secure with adhesive tape.