How long does it take for the Cefekon suppository to work in children?

How to lower a child's temperature? Not all children are able to swallow medicine. For them and for the little ones, candles with antipyretic are suitable. Produced in this form, the product is quickly absorbed and is even more effective.

Cefekon, available only in the form of suppositories, also has a mild analgesic effect, which is why it is used when the baby is teething. It is also suitable if the child feels sick or has frequent vomiting. Suppositories will help if you need to reduce inflammation in the rectum.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Children's Cefekon has an analgesic and antipyretic effect . In the central nervous system, the drug causes a blockade of cyclooxygenase, thereby affecting the pain center and thermoregulation system. At the site of inflammation, the effect of paracetamol on cyclooxygenase is neutralized by cell peroxidase, which significantly reduces the anti-inflammatory effect. Cefekon does not negatively affect the gastrointestinal mucosa and water-electrolyte metabolism, that is, sodium water retention in the body is not observed.

Pharmacokinetics

The drug has high absorption and is quickly absorbed through the mucous membrane. Easily overcomes the BBB. Has high bioavailability. Distributed mainly in body fluids. Protein binding is insignificant (less than 10%). Metabolized in the liver. The maximum concentration of the drug in the blood occurs within 10-60 minutes after taking it. It is excreted by the kidneys in the form of inactive metabolites (sulfates and glucuronides).

Combination with other drugs

Babies under one year old cannot combine the drug with other medications to reduce fever, but even after this age, it is dangerous to take drugs containing paracetamol with Cefekon. Complex use can lead to an overdose and negatively affect liver function.

Ethanol, tricyclic antidepressants, Rifampicin in combination with Cefekon can lead to intoxication because they enhance the effect of paracetamol. In turn, paracetamol enhances the effect of anticoagulants, so giving them at the same time is dangerous.

The use of Nurofen during the period of use of Cefekon is permissible only with an interval of 8 hours.

The active ingredient of Nurofen is ibuprofen, the anti-inflammatory effect of which is stronger than that of paracetamol. However, it has a stronger effect on the stomach and intestines. Inserting 2 suppositories is dangerous, since the baby may respond to such treatment by defecation. For very tiny people, weighing up to 6 kg, Nurofen is completely contraindicated.

Indications for use

The drug is prescribed to children as:

  • antipyretic . Prescribed for influenza , ARVI , post-vaccination reactions, childhood infections and other conditions that cause an increase in body temperature;
  • analgesics and for pain syndrome ( neuralgia , myalgia , headache and toothache, pain from burns and injuries).

Contraindications

Children under 1 month, hypersensitivity to paracetamol, chronic alcoholism. The drug should be prescribed with caution in diseases of the blood system, severe and liver dysfunction , genetically determined enzymatic absence of glucose-6-phosphate dehydrogenase.

Cefekon D - suppositories during pregnancy and lactation can be prescribed taking into account the benefits and risks for the pregnant woman and the child (fetus). Studies have not established the teratogenic, mutagenic and embryotoxic effects of paracetamol .

Negative reactions of the body

When using the drug, negative reactions of the child’s body may occur. Most often they are expressed by malfunctions of the digestive system. This may include abdominal pain, nausea and vomiting.

In case of hypersensitivity to the active ingredient, there is a risk of allergies. It manifests itself

  • Rash.
  • Itching.
  • Hives.

With prolonged use of suppositories, severe negative reactions of the body from the hematopoietic system are observed. Anemia occurs most often, but other pathological conditions that threaten the child’s health are also possible.

An overdose of the drug is dangerous. Its symptoms are pale skin, constant nausea that causes severe vomiting and abdominal pain. Within 12-48 hours, against the background of an overdose, signs of liver failure appear, which is life-threatening.

If you suspect an overdose, you should urgently call an ambulance. After cleansing therapeutic procedures, symptomatic treatment and strict monitoring of blood counts are prescribed.

Instructions for Cefekon D

The suppository is administered rectally to the child or adolescent. The instructions for Cefekon D suppositories for children recommend administering the suppositories after a cleansing enema. The suppository is administered 2-3 times a day. A single dose of Cefekon D on average should not exceed 15 mg per kilogram of a child’s weight, and the maximum daily dose is 60 mg.

A special purpose of the drug is required for children aged 1-3 months - a single administration of one suppository (0.05 g of paracetamol) per day.

At the age of 3 months to one year, with a child weighing 6-10 kg, the dose of the drug is 1-2 suppositories of 0.1 g each; 1–3 years with a body weight of 10–15 kg 1–2 suppositories of 0.1 g; 3–10 years (weight 16–32 kg) 1 candle, 0.25 g; 10–12 years (weight 33–36 kg) 2 suppositories of 0.25 g each.

Tsefekon - suppositories for children, the instructions do not recommend using for a long time. Taking Cefekon D to reduce fever is limited to 3 days, and to relieve pain - use no more than five days.

Special instructions

Before using Cefekon suppositories, you must carefully study the instructions for use. It is imperative to ensure that the amount of active substance used does not exceed the permissible daily allowance in accordance with the age and weight of the child.

If minimal side effects occur during treatment with the drug, you should stop using it and inform your doctor. It is important to exclude other paracetamol-containing drugs during treatment to avoid accidental overdose.

Analogs

Level 4 ATC code matches:
Phenacetin

Combiflu

Chlorphenamine

Coldflu

Calpol

Fervex

Panadol Extra

Panadol for children

Panadol

Solpadeine

Efferalgan

Milistan

Coldrex Maxgripp

Coldrex Hotrem

Coldrex

AntiGrippin

Unispaz

Pentalgin Plus

Rapidol

Maxicold

There are quite a lot of analogues of the drug “children’s Cefekon” containing paracetamol.

Let's mention just a few of them: Paracetamol for children , Children's Panadol , Tylenol for children , Bindard (effervescent powder for children), Dynafed EX , Volpan (powder), Dynafed junior , Dafalgan , Deminofen , Calpol 6 plus , Paracetamol MS , Efferalgan and others.

Reviews of Tsefekon D

On numerous online forums discussing drugs for children, reviews of Cefekon suppositories confirm the high effectiveness of the drug. Cefekon D is especially indispensable in cases where the child categorically refuses to take antipyretics and painkillers in the form of drinks (syrups) or tablets, or the child begins vomiting after taking the syrup.

Some parents, if their child has a fever, give him an antibiotic , which absolutely cannot be done without consulting a doctor. Do not forget that temperature is a protective reaction of the body and does not need to be reduced within moderate limits. Give your child wet wipes and give him plenty of fluids.

Antipyretic suppositories Tsefekon for children are the best option, but we should not forget that children’s suppositories for fever should not be taken for more than 3-5 days. In addition, the drug is not expensive. Information from forums confirms that suppositories for children containing paracetamol are quite popular among parents. People often ask on forums “how long does it take for Cefekon D suppositories to work?” As a rule, the effect appears within 15-20 minutes and lasts up to five hours.

Some parents are faced with the choice “which is better: Cefekon or Nurofen ?” and is it possible to give Cefekon and Nurofen to a child at the same time? These two drugs have different active substances ( paracetamol and ibuprofen ). Everything here is individual. In some cases, Cefekon is more effective, in others - Nurofen. It is not recommended to give Cefekons Nurofen at the same time. If between taking, for example, Nurofen, the temperature rises, reduce it by rubbing it. However, if your child takes Cefekon for five days and the temperature does not drop, then Cefekon must be replaced with another drug. But you cannot give your child one drug between doses of another.

Sometimes parents use adult suppositories to reduce their child's temperature. This cannot be done, since most parents cannot correctly calculate the dose for the child. It is better to use a drug intended for children.

Composition and action of Tsefekon suppositories

In the pharmacy you can find 2 types of medicines, differing in the composition of the active ingredients. Cefekon D, like most modern antipyretics, contains paracetamol. The suppositories also contain solid fat, which allows you to insert the suppository into the anus.

In contrast, Cefekon N contains naproxen, salicylamide and caffeine. Solid fat also acts as a filler.

Cefekon not only reduces temperature, it has an anti-inflammatory effect and relieves pain. When purchasing suppositories, it is useful to look at the marking - the letter, since Cefekon N is intended for patients over 16 years of age.

Price Tsefekon D, where to buy

The price of Tsefekon suppositories for children 0.25 g No. 10 varies between 44 - 58 rubles per package. The price of Tsefekon D suppositories 0.05 g No. 10 is 34-42 rubles, and 0.1 g No. 10 is 38-47 rubles per package. You can purchase the drug in most pharmacies in Moscow and other cities.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in UkraineUkraine
  • Online pharmacies in KazakhstanKazakhstan

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Pharmacy24

  • Cefekon D for children 0.25 g N10 suppositories VAT "Nizhpharm", Nizhny Novgorod, Russian Federation
    39 UAH. order
  • Cefekon D for children 0.1 g No. 10 suppositories VAT "Nizhpharm", Nizhny Novgorod, Russian Federation

    45 UAH order

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