Chlorhexidine vaginal suppositories 16 mg No. 10
A country
Russia
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Active substance
Chlorhexidine
Compound
1 suppository contains: chlorhexidine bigluconate 16 mg
pharmachologic effect
Chlorhexidine is an antiseptic drug for local (intravaginal) use, active against protozoa, gram-positive and gram-negative bacteria, viruses, incl. against Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gononhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex type 2. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria and bacterial spores are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli.
Indications for use
— prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes and others); — prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after installation of an intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine examinations); - treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).
Side effects
Extremely rarely (less than 0.1% of cases) allergic reactions and skin itching are possible, which disappear after discontinuation of the drug.
Contraindications
- childhood;
- hypersensitivity to the components of the drug. Use during pregnancy and lactation Use of the drug during pregnancy and lactation is possible if the expected benefit to the mother outweighs the potential risk to the fetus and child.
Use in children Contraindicated in childhood.
Mode of application
Intravaginally. Having previously freed the suppository from the contour cell packaging, it is inserted into the vagina in a supine position. For treatment: 1 suppository 2 times a day for 7-10 days. If necessary, it is possible to extend the course of treatment to 20 days. For the prevention of sexually transmitted infections: 1 suppository no later than 2 hours after sexual intercourse.
special instructions
Chlorhexidine remains active (albeit somewhat reduced) in the presence of blood and pus.
Overdose
Currently, no cases of drug overdose have been reported.
Interaction with other drugs
Concomitant use with iodine-containing drugs is not recommended if they are used intravaginally. Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Toilet of the external genitalia does not affect the effectiveness and tolerability of Chlorhexidine vaginal suppositories, because the drug is used intravaginally.
Chlorhexidine vaginal suppositories 16 mg 10 pcs (Pharmproekt)
Registration Certificate Holder
PHARMPROJECT (Russia)
Dosage form
Medicine - Chlorhexedine
Description
Vaginal suppositories
white or white with a yellowish tint, torpedo-shaped. Marbling of the surface is allowed.
1 sup.
chlorhexidine bigluconate 16 mg
Excipients
: macrogol 1500 2533.3 mg, macrogol 400 225.2 mg, macrogol 4000 56.3 mg.
Suppository weight:
2.9 g.
5 pieces. — contour cell packaging (2) — cardboard packs.
Indications
Trichomonas colpitis, cervical erosion, vulvar itching, prevention of sexually transmitted diseases (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis); prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth, abortion, before and after installation of an IUD, before and after diathermocoagulation of the cervix, before intrauterine examinations); treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).
Contraindications for use
Hypersensitivity to chlorhexidine.
pharmachologic effect
Antiseptic. Chlorhexidine exhibits a bactericidal effect (against gram-positive and gram-negative bacteria) - at a temperature of 22°C and exposure for 1 minute; fungicidal effect at a temperature of 22°C and exposure for 10 minutes; virucidal effect (against lipophilic viruses).
It affects bacterial spores only at elevated temperatures. It is stable, after treatment of the skin it remains on it in a certain amount sufficient to exhibit a bactericidal effect. Retains activity (albeit somewhat reduced) in the presence of blood, pus, various secretions and organic substances.
Does not have a damaging effect on objects made of glass, plastic and metals.
Drug interactions
Used in a neutral environment; at pH 5-8 the difference in activity is small; at a pH greater than 8, a precipitate forms.
Do not use in combination with anionic compounds, incl. with soap.
Incompatible with carbonates, chlorides, phosphates, borates, sulfates and citrates.
The use of hard water reduces bactericidal properties.
Compatible with drugs containing a cationic group (benzalkonium chloride, cetrimonium bromide).
Dosage regimen
The dose and route of administration depend on the indications and dosage form of chlorhexidine.
Side effect
Allergic reactions:
skin rash, itching, severe allergic reactions, including anaphylaxis.
For the skin and subcutaneous fat:
dry skin, itching, dermatitis, photosensitivity.
Local reactions:
staining of tooth enamel, tartar deposits, taste disturbance.
For vaginal use:
allergic reactions (rash, itching), burning are possible; very rarely - anaphylactic reactions; in some cases - sanguineous vaginal discharge.
special instructions
When used intravaginally, if bloody discharge from the vagina appears, the use of chlorhexidine should be discontinued.
Do not allow chlorhexidine to come into contact with the eyes (with the exception of a special dosage form intended for use in ophthalmology), as well as contact with the meninges and the auditory nerve.
Use during pregnancy and breastfeeding
Restrictions during pregnancy - With caution. Restrictions when breastfeeding - With caution. If use is necessary during pregnancy and breastfeeding, the expected benefits of therapy for the mother should be weighed against the possible risk to the fetus.
Use in elderly patients
Restrictions for elderly patients - No restrictions.
There are currently no restrictions for use in elderly patients.
Use in children
Restrictions for children - With caution.
Use with caution in children.
Chlorhexidine
INSTRUCTIONS for the use of a medicinal product for medical use CHLORGEXIDINE Registration number: LP-001956 Trade name: Chlorhexidine International nonproprietary name: chlorhexidine Dosage form: vaginal suppositories
Compound:
One suppository weighing 1.5 g contains: Active substance: chlorhexidine bigluconate – 8 mg (chlorhexidine bigluconate is used in the form of a solution (20% concentration)). Excipients: macrogol-1500 (polyethylene glycol 1500) – 1311.7 mg, macrogol-400 (polyethylene glycol 400) – 116.6 mg, macrogol-4000 (polyethylene glycol 4000) – 29.1 mg.
One suppository weighing 2.9 g contains: Active substance: chlorhexidine bigluconate – 16 mg (chlorhexidine bigluconate is used in the form of a solution (20% concentration)). Excipients: macrogol-1500 (polyethylene glycol 1500) – 2533.3 mg, macrogol-400 (polyethylene glycol 400) – 225.2 mg, macrogol-4000 (polyethylene glycol 4000) – 56.3 mg. Description: suppositories are white or white with a yellowish tint, torpedo-shaped. Marbling of the surface is allowed.
Pharmacotherapeutic group: antiseptic ATC code: G01AX
Pharmacological properties: Pharmacodynamics Chlorhexidine is an antiseptic drug for topical use, active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes virus. Some strains of Pseudomonas spp., Proteus spp., as well as acid-resistant forms of bacteria, bacterial spores, and fungi are weakly sensitive to the drug. Chlorhexidine does not interfere with the functional activity of lactobacilli. Retains activity, although somewhat reduced, in the presence of blood, pus and other biological fluids.
Pharmacokinetics: When administered intravaginally, it is practically not absorbed and has no systemic effect.
Indications for use: treatment of vaginitis (including acute nonspecific, mixed, trichomonas), prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after installation of an intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine examinations), - prevention of sexually transmitted infections (chlamydia, ureaplasmosis, genital herpes, syphilis, gonorrhea, trichomoniasis).
Contraindications for use: hypersensitivity to the components of the drug. Use the drug with caution in childhood (it is recommended to use the drug Chlorhexidine, vaginal suppositories 8 mg). Dosage regimen, route of administration and duration of treatment Intravaginal. Before use, the suppository is released from the contour packaging. For treatment: 1 suppository 2 times a day, for 7 – 10 days. For the prevention of sexually transmitted infections: 1 suppository no later than 2 hours after unprotected sexual intercourse.
Precautions for use The toilet of the external genitalia does not affect the effectiveness and tolerability of suppositories, because the drug is used intravaginally. Chlorhexidine remains active, although somewhat reduced, in the presence of blood, pus and other biological fluids. Symptoms of overdose, measures to help with overdose Currently, there are no cases of overdose reported.
Side effects Possible allergic reactions, itching, which disappear after discontinuation of the drug. If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor. Interaction with other drugs Concomitant use with iodine-containing drugs is not recommended if they are used intravaginally. Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Features of the medical use of the drug by pregnant women, women during breastfeeding, children, adults with chronic diseases. Can be taken during pregnancy and lactation. Effect of a medicinal product for medical use on the ability to drive vehicles and machinery. The use of the drug does not affect driving or engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Release form: Vaginal suppositories 8 mg and 16 mg. 5 suppositories in a blister pack, 2 blister packs each, along with instructions for medical use, are placed in a cardboard pack.
Storage conditions Store at a temperature not exceeding 25 °C. Keep out of the reach of children.
Shelf life: 2 years. Do not use after the expiration date stated on the package. Dispensing conditions Without a prescription.
When destroying unused packages of the drug, no special precautions are required.
