Polydexa ear drops bottle 10.5 ml + pipette

Polydexa is an original French drug based on two antibiotics and a glucocorticosteroid. Available in two forms - ear drops and phenylephrine nasal spray. The medication is sold strictly according to prescription and is not suitable for self-medication. Since it contains antibiotics, with uncontrolled use there is a high risk of developing resistance of pathogens to the active components.

Pharmacies offer many analogues of the drug, available freely without a doctor's prescription. Before purchasing, you should study the instructions for use and consult with a specialist.

pharmachologic effect

Manufacturer: Farmaster, France
Release form: ear drops, nasal spray (with phenylephrine)

Active ingredients: polymyxin B, neomycin, dexamethasone

Polydex is available in two forms - ear drops and phenylephrine nasal spray. Common components are two antibiotics and a local glucocorticosteroid. Medicines have the following therapeutic effects:

• antibacterial;
• anti-inflammatory;
• vasoconstrictor (typical only for nasal spray).

Polydex medications are dispensed strictly according to a doctor's prescription and are used as directed. Not suitable for self-medication.

With uncontrolled or frequent use, there is a high risk of developing insensitivity of microorganisms to the antibiotics included in Polydex. In the future, this threatens the ineffectiveness of the drug for diseases of the ENT organs and the development of superinfection.

Polydexa - antibiotic or not

A common question among patients is whether Polydexa is an antibiotic or a hormone. This drug contains two antibacterial substances and a hormone for local use (glucocorticosteroid) and belongs to the group of combined drugs.

Polydexa with phenylephrine is a nasal spray. It additionally contains a vasoconstrictor component, which eliminates nasal congestion, swelling and redness (hyperemia) of the mucous membrane.

Indications for use of Polydex

Polydex ear drops are prescribed for otitis externa and infected eczema. Restrictions for use are perforation of the eardrum, individual intolerance to the components, ear diseases of a fungal or viral nature, pregnancy and breastfeeding.

Polydex nasal spray with phenylephrine has a complex effect. Prescribed for the following diseases:

• sinusitis (including sinusitis);
• nasopharyngitis;
• rhinitis.

The drug is used for acute and chronic forms of these diseases. Restrictions - viral diseases, age up to 2.5 years, possible angle-closure glaucoma (due to the content of phenylephrine).

Contraindications

General contraindications to the use of the drug are:

1. ​Individual intolerance to active and auxiliary substances.
2. Damage to the eardrum due to various injuries and infections.
3. ​Time of bearing a child and breastfeeding.
4. ​Children under 2 years old.
5. Glaucoma.
6. Viral pathologies - herpes and chickenpox.
7. ​Serious kidney disease, urinary retention and albuminuria.
8. ​Tachycardia due to the use of pharmacological agents.

It is necessary to use the drug with extreme caution in case of hypertension, ischemic conditions and the presence of symptoms of hyperthyroidism.

Polydex's analogs

The price of Polydex for the ears varies from 260 to 360 rubles, for the nose - from 360 to 480 rubles. It depends on the region, the markup of the pharmacy organization, and the availability of promotional offers from the manufacturer or supplier.

There are no analogues of Polydex with the same composition (2 antibiotics and a hormone). Substitutes differ in their included components, therapeutic effect, cost, and contraindications.

List of Polydex analogues for the treatment of diseases of the nose and ear with approximate prices and country of origin

Analogues in the nose

Derinat

Manufacturer: FZ Immunolex, Russia
Release form: solution

Active ingredient: sodium deoxyribonucleate

Derinat is a domestic analogue of Polydex nasal spray. Available in bottles, the cost depends on the additional nozzle of drops or spray. The medicine is an immunomodulatory drug and helps to activate the body’s own forces to fight viral, fungal, and bacterial infections.

In otolaryngology, Derinat is used as an auxiliary measure for rhinitis, sinusitis, and sinusitis. The advantage of the analogue is that it is cheaper than Polydex spray, it is safe, there are no contraindications (except for reactions of individual intolerance).

Vibrocil

Manufacturer: Novartis, Switzerland
Release form: nasal drops

Active ingredient: phenylephrine, dimethindene

The drug Vibrocil combines the properties of its constituent components - it fights allergic reactions, eliminates swelling of the mucous membrane, redness, nasal discharge, constricts blood vessels, and normalizes breathing. In pediatrics, Vibrocil has been used since one year.

Indications for the use of this Polydex analogue are rhinitis (acute, allergic, chronic), sinusitis, as an adjuvant for otitis media to restore breathing.

Sinupret

Manufacturer: Bionorica, Germany
Release form: drops, tablets

Active ingredient: extracts of medicinal plants

The drug Sinupret is used in pediatrics from 2 years of age and for the treatment of adults with sinusitis. Helps reduce inflammation in the sinuses, liquefy and drain exudate.

The drops contain alcohol, so they are used with caution for diseases of the liver, brain, head injury and alcoholism.

Composition and release form

The drug is dispensed in the following forms:

1. ​Drops - used in the fight against smart pathologies. This is a liquid base, packaged in a 10 ml glass bottle and secondary paper packaging. The kit includes a pipette for convenience.
2. ​Spray is a colorless, odorless, completely transparent liquid. Designed for instillation into the nose. Sold in a 15 ml bottle. The set includes a sprayer. One cardboard box contains 1 bottle and instructions for use are included.

The active substances in the drops are: neomycin sulfate, polymyxidine sulfate, sodium dexamethasone methylsulfobenzoate.

The active ingredients of the spray are the same and additionally includes phenylephrine hydrochloride.

Polydex auxiliary compounds: citric acid, pure water, lithium chloride, macrogol, methylparaben, polysorbate, thiomersal.

Analogs for ears

Dioxidine

Manufacturer: Novosibkhimpharm, Russia
Release form: solution in ampoules

Active ingredient: hydroxymethylquinoxaline dioxide

The drug Dioxidin is often prescribed as an antimicrobial agent for infectious and inflammatory diseases of the ears and nose. Produced in ampoules of 5 and 10 ml, 10 pieces in a package. Two ampoules are required for treatment.

The medicine is dispensed by prescription, strictly as prescribed by the doctor.

Otofa

Manufacturer: Farmaster, France
Release form: ear drops

Active ingredient: rifamycin

Otofa is used as prescribed by a doctor for otitis media and externa, and is an analogue of Polydex. Contains an antibacterial component, approved for use in pediatrics.

Anauran

Manufacturer: Zambon S.P.A., Italy
Release form: ear drops

Active ingredients: polymyxin B, neomycin, lidocaine

Anauran - ear drops similar to Polydex. The difference is that instead of the anti-inflammatory hormone dexamethasone, they contain the local anesthetic lidocaine. Used for external and otitis media.

Candibiotic

Manufacturer: Glenmark, India
Release form: ear drops

Active ingredients: beclomethasone propionate, chloramphenicol, clotrimazole, lidocaine

The candibiotic combines 4 actions at once and is used for external and otitis media:

• antibacterial;
• antimicrobial;
• anesthetic;
• anti-inflammatory.

Can be used in children from 6 years of age.

Important! Drops in the ear are used only after examination and consultation with a specialist. For many, a contraindication is perforation of the eardrum, which is diagnosed by a doctor.

Polydexa ear drops bottle 10.5 ml + pipette

A country

France
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.

Active substance

Dexamethasone + Neomycin + Polymyxin B

Compound

thiomersal, citric acid, sodium hydroxide (1N solution), macrogol 400, polysorbate 80, purified water.

pharmachologic effect

Combined drug for local use in otorhinolaryngology. The therapeutic effect of Polydex is due to the anti-inflammatory effect of dexamethasone and the antibacterial effect of the antibiotics neomycin and polymyxin B. When these antibiotics are combined, the spectrum of antibacterial action expands on most gram-positive and gram-negative microorganisms that cause infectious and inflammatory diseases of the outer and middle ear. Neomycin is active against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae. Polymyxin B is active against gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa. Streptococcus spp. are resistant to these antibiotics. (including Streptococcus pneumoniae) and anaerobic bacteria. In the absence of damage to the eardrum, Polydexa does not have a systemic effect.

Indications for use

- otitis externa (in particular, infected eczema of the external auditory canal).

Mode of application

The drug is prescribed 1-5 drops in each ear 2 times a day for 6-10 days. Before using ear drops, it is recommended to warm the bottle by holding it in your hand to avoid discomfort associated with cold liquid getting into the ear. After instilling the drug into one ear, you should tilt your head in the opposite direction for a few minutes, and then instill it into the other ear. Adequate and strictly controlled clinical studies of the safety of using Polydex during pregnancy and lactation (breastfeeding) have not been conducted.

Interaction

No clinically significant interactions between Polydex and other drugs have been identified.

Side effect

Allergic reactions: rarely - skin manifestations.

Contraindications

- infectious or traumatic damage to the eardrum; - hypersensitivity to the components of the drug.

Overdose

Due to the low degree of absorption into the systemic circulation, an overdose is unlikely.

special instructions

Before starting treatment, it is necessary to examine the condition of the eardrum. In case of perforation of the eardrum, the use of the drug is unacceptable due to the risk of toxic effects on the vestibular and auditory apparatus. If you are allergic to neomycin, cross-allergy with aminoglycoside antibiotics is possible.

Dispensing conditions in pharmacies

On prescription

Polydexa or Isofra - which is better?

Manufacturer: Sofartex, France
Release form: nasal spray

Active ingredient: framycetin

Synonym: Tramicent

Isofra is an analogue of Polydex nasal spray, containing one component - framycetin. Refers to antibacterial drugs, affects pathogenic sensitive microflora - gram-positive and gram-negative bacteria. The medicine is used for sinusitis (sinusitis), nasopharyngitis, rhinitis, green snot, and adenoids. The price of the medicine is slightly lower than Polydex - 330–440 rubles.

Polydexa contains two antibiotics that enhance each other, and a glucocorticosteroid with pronounced anti-inflammatory properties. The composition of the drug is more effective and stronger. An additional substance is phenylephrine, which normalizes breathing by constricting blood vessels and eliminating redness and swelling of the nasal mucosa.

What is best for a child is individual. Both drugs are prescribed by a doctor and are available with a prescription.

Difference between drugs:

• composition – Isofra has only an antibacterial effect, Polydexa has an antibacterial, anti-inflammatory, vasoconstrictor effect;
• due to its composition, Isofra is used in pediatrics from the age of 1 year, Polydexa - from 2.5 years, strictly as prescribed by the doctor;
• an analogue of Polydex spray with Phenylephrine Isofra is slightly cheaper - up to 50 rubles;
• Polydex has more contraindications for use than its analogue.

Both medicines are effective, imported, and of high quality. The choice in favor of one or the other is made by the doctor based on medical history. The undoubted advantage of the medicines is that they are original. This means that they have been sufficiently studied, there is clinical research data on the safety and effectiveness of using nasal spray in adults and children.

Polydexa or Sofradex - which is better in the ear?

Manufacturer: Sanofi India Limited, India
Release form: drops

Active ingredients: dexamethasone, framycetin, gramicidin

Sofradex is an analogue of Polydex ear drops, with a combined composition. It also contains a glucocorticosteroid and two antibacterial components and has an anti-inflammatory and antibacterial effect.

In otolaryngology, an analogue is used for otitis externa, it is more expensive. Which is better – Sofradex or Polydex, individually. The drugs are similar in terms of the included groups of substances and properties.

Side effects

As a rule, side effects rarely occur after taking Polydex ear drops. The only condition that the drug can provoke is allergic reactions. Skin rashes, itching, rarely hyperemia and urticaria are observed.

The nasal spray contains a larger number of active ingredients, therefore it has a wide range of side effects, these are:

1. ​Headache.
2. ​Sleep disturbance.
3. Signs of tachycardia.
4. ​Increased pressure level.
5. Tremor of the limbs.
6. ​Pale or redness of the skin.
7. ​Allergy symptoms - itching, rash, hives.

Polydexa or Rinofluimucil

Manufacturer: Zambon S.P.A., Italy
Release form: spray

Active ingredient: acetylcysteine, tuaminoheptane

Rinofluimucil is an analogue of Polydex with phenylephrine, eliminating swelling of the mucous membrane, normalizing breathing and thinning purulent mucous discharge in the nose. The drug is better for sinusitis if used in combination with antibacterial drugs orally.

The analogue Rinofluimucil is available freely without a doctor's prescription. Indications: sinusitis, vasomotor, chronic rhinitis, with thick purulent mucous secretion.

Restrictions: age under 3 years, angle-closure glaucoma, thyrotoxicosis, complicated course of heart disease.

Polydexa is also used for sinusitis and other types of sinusitis; it has antibacterial, anti-inflammatory and vasoconstrictor effects. The choice of drug is made by the doctor.

Polydexa or Nasonex – which is better?

Manufacturer: Schering-Plough Labo N.V. / Akrikhin, Belgium or Russia
Release form: spray

Active ingredient: mometasone

Synonyms: Mometasone, Momat Rino, Desrinit

An analogue of Polydex with Phenylephrine in a spray is the drug Nasonex. Contains mometasone and is a topical glucocorticosteroid. Available with a prescription, used on the recommendation of a doctor. Has anti-inflammatory and anti-allergic effects.

Indications for the use of the Nasonex analogue are rhinitis, sinusitis, rhinosinusitis in adults and children over 2 years of age in combination with antibacterial drugs.

The difference between Polydexa for the nose and Nasonex is the effect it provides. Polydexa is a complex agent that acts on bacteria. Nasonex – relieves allergies, inflammation, reduces swelling, restores breathing. Can be used in combination with antibiotics if there is intolerance to the components of Polydex in the nose.

Substitutes for Nasonex, belonging to the group of glucocorticosteroids, are available by prescription: Avamis, Nasobek, Flixonase, etc.

Instructions for use of Polydex

Ear drops are convenient to use to treat various conditions in adults and children. The duration of the course and therapeutic dose depend on the diagnosis and severity of clinical signs.

As a rule, 1-2 drops are instilled into the ears twice a day. In complicated conditions, it is permissible to increase the dosage to 5 drops. Before using the product, it needs to be warmed up a little.

The duration of the course of treatment is no more than 10 days.

Polydex nasal spray has a similar application regimen as ear drops. Before spraying, Aeroflot should be shaken and holding the bottle vertically, irrigate the nasal cavity.

Spray dose 1 press in each pass up to 3 times a day. Depending on the age and nature of the disease, the therapeutic dosage can be increased up to 5 times a day.

The course of spray treatment is 5-10 days.

Polydexa or Otipax

Manufacturer: Biocodex, France
Release form: ear drops

Active ingredient: lidocaine, phenazone

Otipax ear drops are a substitute for Polydex, used for otitis media, barotraumatic otitis and inflammation after a cold. It has analgesic and anti-inflammatory effects. Used in pediatrics. Limitations for use include perforation of the eardrum and individual intolerance to the components.

Polydexa has a different purpose - it is used for external otitis and eczema.

The choice of drug should be entrusted to the doctor in order to make a diagnosis and exclude perforation of the eardrum.

special instructions

It is highly not recommended to use the drug in any form for more than 10 days and in the presence of damage to the eardrum.

After opening the bottle, it must be hermetically sealed and the treatment procedure must be carried out only with clean hands, since the likelihood of contamination of the drug with pathogenic organisms increases.

Polydexa does not have any negative effect on concentration, therefore, during the course of therapy it is not prohibited to personally drive a car.

Polydexa or Protargol

Manufacturer: Pharmvilar, Kirov FF, Russia
Release form: powder with solvent

Active ingredient: silver proteinate

Synonyms: Sialor

Protargol is an analogue of Polydex for children and adults based on silver ions with an antiseptic effect. Available in powder and solvent form, when combined they form nasal drops. The resulting solution is stored for up to 30 days in a place protected from light (cabinet).

Protargol is a nasal analogue that is cheaper than Polydexa and is used for rhinitis and sinusitis for up to 5-7 days. After instillation, a film is formed on the mucous membrane, preventing the proliferation of the pathogen. Dry mouth, burning sensation, tingling sensation, and allergic reactions are also possible.

Polydexa has a wider spectrum of action and is used as prescribed by a doctor.

What to replace Polydex with depends on many factors (cause, symptoms of the disease, duration, age of the patient, restrictions, previously used drugs, etc.). Polydex analogues for children for the nose and ear are selected with a pediatrician. For treating adults, consulting a doctor is also important.