Pharmacy No. 84. Delivery of medicines to your home and office.

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Hepilor (spray)

From the immune system: hypersensitivity reactions, including urticaria, angioedema, laryngospasm, bronchospasm.

From the nervous system: ageusia, dysgeusia, change in taste sensations within 48 hours (the sensation of “sweet” can change twice

From the immune system: hypersensitivity reactions, including urticaria, angioedema, laryngospasm, bronchospasm.

From the nervous system: ageusia, dysgeusia, change in taste sensations within 48 hours (the sensation of “sweet” can change twice to the sensation of “bitter”).

From the respiratory system, chest and mediastinal organs: cough, shortness of breath.

From the digestive system: dry mouth, dysphagia, enlarged salivary glands, pain when swallowing. If the drug is accidentally ingested, gastrointestinal disorders may occur, primarily nausea and vomiting.

From the skin and subcutaneous tissue: allergic contact dermatitis, skin reactions (rash).

General disorders and condition of the application site: local reactions - reversible change in the color of teeth and tongue; sensitivity of the mucous membrane, namely burning, numbness; irritation (pain, feeling of heat, itching) of the tongue and/or oral mucosa; decreased sensitivity; paresthesia of the mucous membrane; inflammation; bubbles; the occurrence of ulcers on the mucous membrane, a sore throat, swelling at the site of contact, dryness of the mucous membrane of the nose/throat.

pay attention to the feeling of “bitter”).

From the respiratory system, chest and mediastinal organs: cough, shortness of breath, sore throat.

From the skin and subcutaneous tissue: allergic contact dermatitis, skin reactions (rashes).

General disorders and condition of the application site: local reactions - reversible change in the color of teeth and tongue; sensitivity of the mucous membrane, namely burning, numbness; irritation (pain, feeling of heat, itching) of the tongue and/or oral mucosa; decreased sensitivity; paresthesia of the mucous membrane; inflammation; bubbles; the occurrence of ulcers on the mucous membrane, swelling at the site of contact, dryness of the mucous membrane of the nose/throat.

If any adverse reactions occur, you should stop using the drug and be sure to consult a doctor.

Overdose

If a sufficient amount of Hepilor oral solution or spray is absorbed, alcohol intoxication may occur due to the ethyl alcohol content.

The concentration of hexetidine contained in Hepilor oral solution or spray is not toxic if the drug is used as directed.

The occurrence of acute alcohol intoxication is extremely unlikely. If a child swallows a significant dose of the drug, alcohol intoxication may occur due to the ethyl alcohol content.

There are no cases of excessive use of hexetidine, which led to hypersensitivity reactions.

Treatment: symptomatic. If a child swallows the contents of the bottle, consult a doctor immediately. It is necessary to consider the possibility of performing gastric lavage within 2 hours after ingestion and take measures to eliminate signs of alcohol intoxication.

Application

Apply topically.

Solution for rinsing the mouth

For one mouth rinse for adults and children over 6 years of age: pour the solution into a measuring cup until 10 ml is divided and dissolve in 50 ml of warm water or dissolve 2 teaspoons of the drug in ¼ glass of warm water. From 2 to 4 rinses per day. Do not swallow. The course of treatment is no more than 5 days.

Spray

Adults and children over 15 years of age: 1 spray 4–6 times a day.

Children aged 6 to 15 years: 1 spray 2-3 times a day.

The course of treatment is no more than 5 days.

Note!

Description of the drug Hepilor spray for mouth. floor. fl. 50ml on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Pharmacological properties

Pharmacodynamics.
The effect of the drug is due to three active ingredients. Antibacterial and antifungal activity

Hexetidine has an antibacterial effect on both gram-positive and gram-negative strains of microorganisms, both aerobes and anaerobes.

In relation to aerobic strains, hexetidine mainly has a bacteriostatic effect, the bactericidal effect is weak. Regarding anaerobic strains, hexetidine has a pronounced bactericidal effect. The mechanism of action of hexetidine is a competitive action with thiamine: its structure is similar to the structure of thiamine, which is necessary for the growth of microorganisms.

Anti-inflammatory activity

Choline salicylate has analgesic, antipyretic and anti-inflammatory effects.

Analgesic activity is provided by chlorobutanol. Used in otolaryngology (nasal drops, rinses) and in dental practice (applications and irrigation) as an anesthetic.

Pharmacokinetics. The active substances are fixed on the oral mucosa, from where they are gradually released.

Hepilor mouth rinse solution

Instructions for medical use of the drug

Description of pharmacological action

The effect of the drug is due to three active components. Antibacterial and antifungal activity. Hexetidine has an antibacterial effect on both gram-positive and gram-negative strains of microorganisms, both aerobes and anaerobes. It should be noted that it has a mainly bacteriostatic effect on aerobic strains; the bactericidal effect is weak. Hexetidine has a pronounced bactericidal effect on anaerobic strains. The mechanism of action is a competitive action with thiamine: the chemical structure of hexetidine is similar to the structure of thiamine, which is necessary for the growth of microorganisms. Anti-inflammatory activity. Choline salicylate has analgesic, antipyretic and anti-inflammatory effects (oral diseases). Analgesic activity is provided by chlorobutanol. Used in otolaryngology (nasal drops, rinsing) and in dental practice (applications and irrigation) as an anesthetic. The active substances are fixed on the oral mucosa, from where they are gradually released.

Indications for use

Local treatment of infectious diseases of the oral cavity and pharynx: sore throat, acute and chronic tonsillitis, pharyngitis, laryngitis; gingivitis, stomatitis, aphthae. Oral care after dental interventions.

Release form

solution for rinsing the mouth: bottle 100 ml, No. 1

Contraindications for use

The solution should not be used in children under 6 years of age; the spray should not be used in children under 12 years of age. Do not use if you are allergic to any of the components of the drug. Hypersensitivity to any of the components of the drug.

Side effects

The drug may cause allergic reactions: mild irritation of the oral mucosa, skin reactions; Possible disturbance of taste and smell. In this case, it is necessary to stop treatment. Risk of sensitization to one of the components of the drug.

Directions for use and doses

Apply topically. Mouth rinse solution: pour the solution into a measuring cup to the 10 ml mark and dissolve in 50 ml of warm water, or dissolve 2 teaspoons of the drug in ¼ glass of warm water. Carry out 2–4 rinses per day. Do not swallow. The course of treatment is 5 days.

Overdose

There have been no reports of drug overdose.

Interactions with other drugs

Should not be used simultaneously with medications containing antiseptics.

Special instructions for use

When using, do not swallow and avoid contact with eyes, as the drug contains ethanol. Long-term use is not recommended - the natural microbial balance of the mouth and throat may change, where there is a risk of the spread of bacteria and fungi. If general clinical signs of a bacterial infection appear, general antibacterial therapy should be provided. If symptoms persist for more than 5 days and/or body temperature rises, treatment tactics should be reconsidered. Use during pregnancy and lactation. During pregnancy and lactation, the drug is used only as prescribed by a doctor and only when the benefit to the mother outweighs the risk to the fetus.

Storage conditions

At a temperature not higher than 25˚С. Do not freeze!

Best before date

12 months

ATX classification:

R Respiratory system

R02 Preparations for the treatment of throat diseases

R02A Preparations for the treatment of throat diseases

special instructions

When using the drug, do not swallow and avoid contact with eyes; use caution in patients with liver disease, since the drug contains ethanol.

The drug should be used with caution in patients with epilepsy. The drug may lower the epileptic threshold and cause seizures in children. Use with caution in patients with allergic reactions.

There is a risk of laryngospasm in children due to the presence of levomenthol.

Long-term use is not recommended as it may alter the natural microbial balance of the mouth and throat, where there is a risk of bacterial or fungal spread.

If general clinical signs of a bacterial infection appear, general antibacterial therapy should be provided.

If symptoms persist for more than 5 days and/or body temperature increases, if inflammation increases, drug therapy should be discontinued and treatment tactics should be reconsidered.

Use during pregnancy or breastfeeding. There are no data from human studies on the possibility of hexetidine crossing the placenta and excretion into breast milk, therefore the drug should not be used during pregnancy or breastfeeding.

Children. Use the drug in children over 6 years of age.

The ability to influence reaction speed when driving vehicles or working with other mechanisms. The drug contains ethanol. Drivers are not recommended to drive a vehicle for 30 minutes after using the drug.