Pharmacological properties
Folic acid
, a B vitamin, plays an important role in the synthesis of nucleic acids and the conversion of essential amino acids. When folic acid is taken before conception and early in pregnancy, the risk of neural tube defects in newborns is reduced.
The need for folic acid salts especially increases during pregnancy due to embryogenesis and rapid fetal growth.
With a lack of folic acid salts, the synthesis of DNA necessary for cell division, as well as the synthesis of some proteins and lipids, decreases. In early pregnancy, this disorder can cause neural tube defects in the newborn. Low levels of folic acid salts in the blood have been found in women who gave birth to children with a neural tube defect.
Iodine
promotes the normal functioning of the thyroid gland, is part of its hormones (thyroxine, triiodothyronine). Prevents the development of endemic goiter and cretinism. When iodides enter the epithelial cells of the thyroid follicle, under the influence of the enzyme iodide peroxidase, iodine is oxidized to form elemental iodine, which is included in the tyrosine molecule. In this case, one part of the tyrosine radicals in Thyroglobulin is iodinated. Iodinated tyrosine radicals condense into thyrotrons, the main of which are thyroxine (T4) and triiodothyronine (T3). The resulting complex of thyronine and thyroglobulin is released as a deposited form of thyroid hormone into the follicle colloid and remains in this state for several days or weeks. With iodine deficiency, this process is disrupted. Potassium iodide compensates for its deficiency and helps restore impaired synthesis of thyroid hormones. An important property of potassium iodide is its ability to prevent the accumulation of radioactive iodine in the thyroid gland and provide its protection from radiation.
IODOPHOL TAB No. 60
Instructions
Trade name of the drug: Yodofol
Active ingredients: Comb.drug (potassium iodide, folic acid)*
Pharmacotherapeutic group: Iodine preparations., Iodine preparations.
Release form:
Pills. 30 tablets in a blister or 150 tablets in a polypropylene dispenser. 1, 2 or 3 blisters or 1 dispenser along with instructions for use in a cardboard box.
Dosage form: Tablets (200 mcg/400 mcg) N30, N60, N90 (blisters), N150 (dispenser bottles)
Compound:
One tablet contains: active substances: potassium iodide – 200 mcg, which corresponds to 150 mcg of iodine, folic acid – 400 mcg. excipients: lactose monohydrate, microcrystalline cellulose, silicic acid, glucose, talc, magnesium stearate.
Pharmacological properties:
Iodine contributes to the normal functioning of the thyroid gland and is part of its hormones (thyroxine, triiodothyronine). Prevents the development of endemic goiter and cretinism. Folic acid deficiency causes impaired DNA synthesis in the cell preparing for chromosome replication and division. The mechanism of action is due to the participation of folic acid in the form of tetrahydrofolate in the synthesis of nucleic acids and in cell division, as well as participation as a coenzyme in the synthesis of purines and pyrimidines, which makes it a decisive factor in the formation of the central nervous system, which develops in humans on days 15-28 after fertilization. Folic acid is necessary for normal maturation of megaloblasts and the formation of normoblasts. Its deficiency leads to the accumulation of homocysteine in the blood plasma, which is a marker of atherosclerotic changes.
Indications for use:
• prevention and compensation of iodine and folic acid deficiency in women during pregnancy planning, as well as during pregnancy and lactation; • prevention of intrauterine anomalies in the development of the nervous system, limbs, heart; • prevention of growth disorders and puberty in adolescents; • state of chronic fatigue, memory impairment; • peripheral neuropathies; • prevention of relapses after therapeutic treatment of iodine deficiency goiter.
Mode of application:
Iodofol is taken orally, 1 tablet per day during or after meals, with a sufficient amount of water. The duration of the course of taking the drug is determined by the doctor.
Side effects: Allergic reactions to the components of the drug are possible.
Contraindications: • hypersensitivity to the components of the drug; • hyperthyroidism.
Drug interactions:
The drug Yodofol should not be taken in combination with analgesics, anticonvulsants, antacids, cholestyramine, sulfonamides, antibiotics, cytostatics, as they reduce the absorption of folic acid. With simultaneous use of Iodofol with potassium-sparing diuretics, hyperkalemia may develop. The simultaneous use of Iodofol and lithium preparations contributes to the development of goiter and hypothyroidism.
Special instructions:
If you have thyroid disease or are using other iodine preparations, you should consult your doctor before using the drug. Effect on the ability to drive vehicles and operate machinery The drug does not affect the ability to drive a car or operate machinery. The drug should be stored out of the reach of children and not used after the expiration date.
Storage conditions: Store in a place protected from moisture and light at a temperature not exceeding 25ºС.
Shelf life: 3 years.
Dispensing conditions: Without a prescription.
Manufacturer: World Medicine Limited, UK made: Kendy LTD, Bulgaria
Release form
Tablets 95 mg No. 150 in a dispenser.
pharmachologic effect
Improves metabolic processes and reproductive function.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Not a medicine. A source of iodine and folic acid, the tablets contain the body's daily requirement for them.
Iodine is necessary for the normal functioning of the thyroid gland, since it is part of its hormones and must be supplied daily with food. Taking iodine supplements prevents the development of iodine deficiency goiter.
A lack of folic acid in the body leads to disruption of DNA synthesis in a cell that is preparing to divide. Folic acid is involved in the synthesis of nucleic acids (in the form of tetrahydrofolate), purines and pyrimidines (as a coenzyme), so it plays a decisive role in the formation of the central nervous system (formed 17-28 days after conception).
Taking folic acid and iodine by adolescents during puberty increases physical performance, reduces fatigue, promotes the normal functioning of the body as a whole and the reproductive system, in particular, and helps reduce overall morbidity.
Pharmacokinetics
Folic acid is well absorbed from the gastrointestinal tract. Intensively binds to blood proteins. Cmax is determined after 30 - 60 minutes. Metabolized in the liver to tetrahydrofolic acid. It is excreted by the kidneys in the form of metabolites.
Potassium iodide is quickly absorbed from the gastrointestinal tract. Bioavailability is 100%. Within 2 hours it is distributed in all tissues. Accumulates in the thyroid gland, salivary and mammary glands. It is excreted by the kidneys and partially with the secretions of the bronchial, salivary and sweat glands.
Indications for use
- replenishment of deficiency in women when planning pregnancy, during pregnancy and breastfeeding;
- prevention of intrauterine fetal anomalies;
- prevention of puberty disorders in adolescents;
- chronic fatigue, memory impairment;
- prevention of relapses of iodine deficiency goiter;
- peripheral neuropathies.
Contraindications
Iodofol is contraindicated in:
- hyperthyroidism;
- hypersensitivity to the product.
Side effects
Iodofol may cause the following unwanted reactions:
- skin itching, rash;
- nausea.
Instructions for Iodofol (Method and dosage)
The tablets are taken orally, 1 tablet per day during meals with plenty of water. Take for 1 month. Further appointments are agreed with the doctor.
The instructions for use contain a warning that before starting to take a dietary supplement, you must consult a doctor, since iodine preparations are not indicated for some diseases of the thyroid gland.
Overdose
When taking the recommended dose, an overdose is not observed.
Interaction
When used with potassium-sparing diuretics, hyperkalemia develops.
The drug should not be combined with antibiotics, analgesics, antacids, sulfonamides, anticonvulsants, cholestyramine, cytostatics, since the absorption of folic acid is reduced.
The simultaneous use of lithium preparations leads to the development of goiter and hypothyroidism.
Terms of sale
Over the counter.
Storage conditions
At a temperature of no more than 25 C.
Best before date
3 years.
Iodofol during pregnancy
According to the recommendations of the Ministry of Health (Order of the Ministry of Health of Russia dated November 12, 2012 No. 572n), the list of therapeutic measures during pregnancy includes the mandatory intake of folic acid by a woman up to 400 mcg / day (the entire first trimester, and longer if indicated) and potassium iodide 200-250 mcg per day. throughout pregnancy and lactation.
These appointments have justifications. Folic acid is prescribed to women planning pregnancy and pregnant women to prevent fetal malformations. Its deficiency during pregnancy causes anemia, miscarriage and premature birth.
Timely correction of iodine deficiency reduces the incidence of complications during pregnancy—the threat of miscarriage is reduced by 8 times. Iodine is also necessary for normal fetal development. It is not synthesized in the body and must be supplied daily through the mother's diet. At 10–12 weeks, the thyroid gland in the fetus is already functioning, capturing iodine from the mother’s body, which can lead to disruption of its function (formation of a goiter in a pregnant woman).
Serious consequences of iodine deficiency in the fetus are a slowdown in the formation of the bone skeleton, lungs, hearing pathology, a slowdown in the development of the brain and the central nervous system in general. Subsequently, the child develops attention deficit disorder and hyperactivity.
Based on the above, Iodofol is prescribed as a vitamin and mineral complex for women planning pregnancy, pregnant and lactating mothers. This biological supplement should be taken 3-5 months before the planned pregnancy after stopping taking contraceptives and during pregnancy. The duration of treatment in this case is recommended by the gynecologist.
This food supplement prevents intrauterine anomalies of the nervous and cardiovascular systems and fetal limbs. Improves the function of the thyroid gland of a pregnant woman, restores the body's adaptation processes. This product is effective and safe for a woman and her unborn child.
Instructions for Iodofol during pregnancy
The food supplement is taken 1 tablet 1 time per day with meals.
For better digestibility, it is recommended to limit the consumption of fats and carbohydrates (sugar, sweets, baked goods). Attention! The description of the drug on this page is simplified. Before purchasing and using the drug, consult your doctor or pharmacist, and also read the instructions approved by the manufacturer. Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. ATTENTION! This section is provided for informational purposes only and is not a catalog or price list of our company. To obtain information about the availability of drugs, call + 99871 202 0999 Pharmacy Network Helpline 999.
Iodofol during pregnancy
According to the recommendations of the Ministry of Health (Order of the Ministry of Health of Russia dated November 12, 2012 No. 572n), the list of therapeutic measures during pregnancy includes the mandatory intake of folic acid by a woman up to 400 mcg / day (the entire first trimester, and longer if indicated) and potassium iodide 200-250 mcg per day. throughout pregnancy and lactation.
These appointments have justifications. Folic acid is prescribed to women planning pregnancy and pregnant women to prevent fetal malformations. Its deficiency during pregnancy causes anemia , miscarriage and premature birth.
Timely correction of iodine deficiency reduces the incidence of complications during pregnancy—the threat of miscarriage is reduced by 8 times. Iodine is also necessary for normal fetal development. It is not synthesized in the body and must be supplied daily through the mother's diet. At 10–12 weeks, the thyroid gland in the fetus is already functioning, capturing iodine from the mother’s body, which can lead to disruption of its function (formation of a goiter in a pregnant woman).
Serious consequences of iodine deficiency in the fetus are a slowdown in the formation of the bone skeleton, lungs, hearing pathology, a slowdown in the development of the brain and the central nervous system in general. Subsequently, the child develops attention deficit disorder and hyperactivity .
Based on the above, Iodofol is prescribed as a vitamin and mineral complex for women planning pregnancy, pregnant and lactating mothers. This biological supplement should be taken 3-5 months before the planned pregnancy after stopping taking contraceptives and during pregnancy. The duration of treatment in this case is recommended by the gynecologist.
This food supplement prevents intrauterine anomalies of the nervous and cardiovascular systems and fetal limbs. Improves the function of the thyroid gland of a pregnant woman, restores the body's adaptation processes. This product is effective and safe for a woman and her unborn child.
Instructions for Iodofol during pregnancy
The food supplement is taken 1 tablet 1 time per day with meals. For better digestibility, it is recommended to limit the consumption of fats and carbohydrates (sugar, sweets, baked goods).
Iodofol price, where to buy
Buy this drug in some Moscow pharmacies, specialized stores selling dietary supplements and healthy food products, and departments of retail chains. Price of Iodofol 150 tablets. ranges from RUB 494. up to 520 rub.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
LuxPharma* special offer
- Iodofol tab.
N60 1370 rub. order
show more
Pharmacy24
- Iodofol No. 60 tablets Kendi LTD, Bulgaria
95 UAH. order
PaniPharmacy
- Iodofol No. 60 Bulgaria, Kendy
107 UAH order
show more
Precautionary measures
Consultation with a physician is recommended before use.
When planning pregnancy, the dietary supplement should be added to the diet after stopping the use of contraceptives and preferably no later than 4 weeks before the start of pregnancy.
Before starting use and when using it simultaneously with any medications, consult a doctor.
Do not exceed the recommended daily dose.
The dietary supplement should not be used as a substitute for a complete diet.
Not a medicine.
Reviews of Iodofol
Analyzing the reviews, we can conclude that this food supplement is often prescribed for chronic fatigue, memory loss, hair loss and split nail plates.
“The child has a bad memory. We took a course of Iodofol - the result is fantastic: memory has improved significantly, the child has become more active."
“They prescribed it to my teenage son: he complained of fatigue, headache, and poor memory. I took iodofol for a month and were pleased with the results.”
Reviews of Iodofol during pregnancy are very common, since it is prescribed to all pregnant women. The duration of taking the drug in each case is different - it depends on the condition of the pregnant woman, the function of the thyroid gland, and the region of residence. In areas where goiter is endemic, the drug was prescribed several months before pregnancy and throughout the entire period of pregnancy and lactation. This issue is resolved by a gynecologist and endocrinologist. Reviews are only positive, only occasionally there are complaints about poor tolerability and side effects.
“I drank before pregnancy and during pregnancy, I felt great. A package of 150 pieces is enough for 5 months"
“I started taking Iodofol from the 5th week of pregnancy until birth - the child was born healthy, he has a good memory”
“I took 1 tablet a day throughout my pregnancy - the baby is healthy”
“I took it while planning my pregnancy and up to 12 weeks. There were no side effects"
“At the 5th week of pregnancy, fatigue, lethargy and headache appeared, Iodofol was prescribed. The headache went away, but the pills caused nausea and stomach pain.”
“...I stopped taking it because immediately after taking it I started to feel nauseous and dizzy.”
Interaction
When used with potassium-sparing diuretics, hyperkalemia develops .
The drug should not be combined with antibiotics , analgesics , antacids , sulfonamides , anticonvulsants , cholestyramine , cytostatics , since the absorption of folic acid is reduced.
The simultaneous use of lithium leads to the development of goiter and hypothyroidism .
