Combilipen: how much to inject and whether to dilute


Compound

Active components of the injection solution Combilipen:

  • Vitamin B6 (Pyridoxine hydrochloride)
  • Vitamin B1 (Thiamin hydrochloride)
  • lidocaine hydrochloride
  • Vitamin 12

Excipients of the drug:

  • potassium hexacyanoferrate
  • sodium tripolyphosphate
  • purified water
  • benzyl alcohol

Active components of tablet form:

  • benfotiamine
  • pyridoxine hydrochloride
  • cyanocobalamin

Additional substances:

  • microcrystalline cellulose
  • carmellose sodium
  • Povidone K30
  • sucrose

Indications for use of cyanocobalamin

Vitamin B12 in ampoules

used as adjunctive therapy. It enhances the effect of drugs and helps the body overcome many diseases. In rare cases, it is prescribed as the only means to prevent anemia.

Indications for use of vitamin B12:

  • chronic migraine;
  • Down syndrome;
  • cerebral palsy;
  • neuralgia;
  • radiation sickness;
  • alcohol poisoning;
  • dystrophy;
  • anemia;
  • radiculitis;
  • diseases of the pancreas and liver;
  • gastritis;
  • photodermatosis;
  • sclerosis.

Taking cyanocobalamin is indicated for vitamin deficiency and frequent respiratory diseases. A lack of substance in the body leads to deterioration of the condition of hair, nails and teeth. For this reason, the drug is taken in ampoules not only for therapeutic purposes, but also for cosmetic purposes.

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pharmachologic effect

The drug is a multivitamin complex, among the components there are several components:

  • Vitamin B1 (thiamine hydrochloride) provides the necessary amount of glucose to nerve cells. Glucose deficiency provokes deformation and enlargement of nerve cells, which causes disruption of their functions.
  • Vitamin B6 (pyridoxine hydrochloride) is a direct participant in the metabolic processes of the central nervous system
  • Vitamin B 12 is involved in the combination of myelin, folic acid, nucleic acids

Kinds

What injections are given for osteochondrosis of the cervical spine and other areas of the spine is chosen for each patient by the attending doctor. The following groups of drugs are used:

  • analgesics;
  • NSAIDs;
  • hormonal;
  • muscle relaxants;
  • chondroprotectors;
  • vitamins;
  • improving blood circulation;
  • homeopathic.

Injections for osteochondrosis of the thoracic region are prescribed less often than for neighboring parts of the spine, since it is less susceptible to degenerative changes.

Non-steroidal anti-inflammatory injections

NSAIDs for spinal osteochondrosis are considered one of the most effective in the fight against inflammation, quickly and permanently eliminating pain and swelling. Due to the fact that they stop the action of prostaglandins, the inflammatory process stops. In addition, the sensitivity of the nerve plexuses and endings is blocked. Long-term use can cause abdominal and headache pain, dyspeptic disorders, dizziness, skin rash and other undesirable symptoms, including gastric bleeding.

Ortofen

The active ingredient is diclofenac sodium. One injection lasts for 12 hours. Usually a one-week course is required.

Ketorolac

The active substance is ketoprofen. Considered a strong analgesic. It is given for 1 week, 2 times a day.

Meloxicam

The drug is a selective COX-2 inhibitor, as a result of which it has fewer side effects. The course of therapy lasts on average 7-10 days, 2 injections per day.

Movalis

This is a German drug based on meloxicam. The product is injected deep into the muscle, providing an effect for 24 hours. The course lasts no more than a week.

Diclofenac

This non-steroidal anti-inflammatory drug is considered the “gold” standard. It is most often used for injections for lumbar osteochondrosis and other diseases of the musculoskeletal system.

Blockades

Nerve blocks are performed only for emergency indications. One or several drugs are administered, differing in the mechanism of action on the site of inflammation.

Novocaine

Included in the list of vital medications. It is a local anesthetic with a wide range of therapeutic effects. Quickly relieves pain.

Dexamethasone

A synthetic glucocorticosteroid with anti-inflammatory, antiallergic and immunosuppressive effects.

Prednisolone

A hormonal remedy to help in emergency situations with spinal osteochondrosis.

Muscle relaxants

Muscle relaxing injections for osteochondrosis are included in the treatment regimen to relieve muscle spasm, restoring normal blood circulation and the flow of nerve impulses.

Mydocalm

The active substance is tolperisone. Has a central effect on skeletal muscles.

Chondroprotectors

Course injections of chondroprotectors for spinal osteochondrosis help restore cartilage tissue, stopping the processes of its destruction.

Elbona

A Russian drug based on glucosamine sulfate.

Alflutop

The active component is represented by a biological concentrate obtained from small marine fish.

Mucosat

The active ingredient is chondratin sulfate.

Rumalon

Peptide complex from cartilage tissue and bone marrow of calves.

Vitamins

Vitamin injections are prescribed after relief of an “acute condition” and to prevent exacerbations of osteochondrosis.

Milgamma

A German drug consisting of B vitamins and lidocaine. It has a complex effect on the spine and the body as a whole. Metabolic processes, tissue trophism, and nervous system function improve.

Combilipen

Russian analogue of Milgamma. Has a good therapeutic effect. Injections for osteochondrosis are given for 5-10 days.

How much to inject Combilipen

Injection solutions are intended for intramuscular administration. For pronounced symptoms of the disease, injections of 2 ml of the drug are given every day for 7 days. After the administration of the medication, it is necessary to continue for another 2 weeks, only during this time injections are given only 2-3 times a week.

A mild form of the disease involves injection 2 or 3 times a week for 10 days.

The treatment course using the Kombilipen injection solution should be carried out for no more than 14 days. The dosage must be adjusted by a specialist.

Pros and cons of injections for osteochondrosis

Injections for osteochondrosis have a number of advantages over non-injection forms of drugs:

  • the entire dose of the substance enters the bloodstream, so it is easy to calculate;
  • immediate effect (in 2-3 minutes);
  • maximum effectiveness, especially when using droppers;
  • no negative effect on the gastrointestinal tract;
  • When the drug is administered locally, it acts directly on the source of inflammation and pain, without affecting other body systems (minimum side effects).

Self-injections for osteochondrosis of the cervical spine and other areas of the spine can provoke a number of serious complications. Disability and death cannot be ruled out.

Even the most effective injections for osteochondrosis have their drawbacks:

  • local complications (hematoma, vessel damage, etc.);
  • pain and discomfort during insertion;
  • general complications (infection, embolism, etc.);
  • the need to visit a treatment room for several days or call a medical professional at home;
  • the possibility of increased pain after the action of the drug and the appearance of an “addiction symptom” when the patient requires a stronger drug or an increased dose of the drug.

Considering the high likelihood of complications, treatment with injections for osteochondrosis of the lumbosacral spine and other areas should be carried out under the supervision of a doctor.

Overdose and its dangers

When using large dosages, the symptoms of the negative effects of the drug intensify.

Signs of overdose:

  • dizziness
  • tachycardia
  • allergic reaction
  • nausea, vomiting

If you have symptoms of overdose, you should:

  • perform gastric lavage
  • carry out symptomatic therapy
  • take activated charcoal

Forms of injections for osteochondrosis

What injections are prescribed for osteochondrosis of the lumbar region and other areas of the spine depends on the specific situation. Orthopedists, traumatologists and neurologists practice an integrated approach to treatment. The doctor prescribes a treatment regimen consisting of several drugs.

Intramuscular injections for osteochondrosis

What injections are given for osteochondrosis? Most often, the answer is clear - into the muscle. This method is considered the simplest and most accessible for the patient. The medicine, entering the muscle tissue, gradually penetrates through small vessels into the general bloodstream, providing a long-term therapeutic effect. Intramuscular injections for spinal osteochondrosis are prescribed in the acute period and in the remission stage.

Intravenous injections for osteochondrosis

Injections into a vein are indicated for severe unbearable pain, when it is necessary to achieve a positive effect as soon as possible. After the injection, the active substance immediately enters the bloodstream without loss. If you need to administer a large volume of medication, it is preferable to install a dropper. Intravenous injections for osteochondrosis of the cervical spine are often prescribed for severe compression of the vertebral arteries, when the blood supply to the brain is disrupted.

Nerve blockades

Spinal nerve blocks must be performed by a physician skilled in this technique. In “inept hands” the procedure can result in serious consequences (paralysis, sepsis, death). The drug is injected into trigger points (paravertebral) or directly into the epidural space to instantly reach nerve endings, relieve pain, vasospasm and swelling.

Cyanocobalamin treatment regimen

When vitamin B12 is prescribed, instructions for use

will help you calculate the correct dosage. The treatment plan looks like this:

  • For the prevention of anemia and vitamin deficiency - from 200 to 500 mcg per day. The course of treatment ranges from 7 to 15 days.
  • For the treatment of diseases of the central nervous system - 200 mcg per day daily for the first 3 days. Then 300 mcg daily for 4 days.
  • If cyanocobalamin is used in complex therapy, the dosage is from 200 to 500 mcg per day.

Take vitamin B12

It is necessary only in the dosage recommended by the doctor. It is not recommended to use the drug on your own, since it is quite difficult to determine an individual treatment regimen.

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What does the choice depend on?

The doctor determines the form of administration, relying not only on those drugs that are available. He pays attention to the patient’s age, gender, financial capabilities, and even his mood and attitude towards treatment. Children require special attention.

“Choosing the form of a drug is partly a creative process,” says Ekaterina Bokova, a therapist at the 120 to 80 clinic. “There are no ready-made solutions here. But most often we focus on age. If this is a very young baby, then we choose liquid or rectal forms to prevent spitting and choking. This way, the child will receive his dose of the active substance with a greater guarantee. Sometimes you even have to make a choice in favor of an injectable drug. In any case, a child should not be prescribed “adult” pills and divided into parts.”

The wishes of the patient or relatives also matter when choosing the form of the medicine. For older people, it is important to take fewer pills per day, otherwise you can get confused, especially if there are a lot of medications. In such cases, tablet holders or planners help.

“Unfortunately, older people usually insist on prescribing the most affordable drug,” says Ekaterina Bokova, “here, if possible, we will meet them halfway.”

How to give injections

Vitamin B12 injections

can be done in different ways:

  • subcutaneously;
  • intramuscularly;
  • intravenously;
  • into the spinal cord.

The instructions say that cyanocobalamin cannot be used simultaneously with drugs that increase blood clotting, as well as with vitamins B1 and B6. If you have an allergy to B1, then B12 can make it worse.

Administer the drug intramuscularly and intravenously

you can do it yourself. For injection into the spinal cord, you should consult an experienced doctor.

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