Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Vitamins Kvadevit normalize metabolism in the body. The dose of each component is close to the physiological norm.
- Vitamin A is necessary for the construction of epithelial cells, ensures the function of the skin and mucous membranes, and the organ of vision. Supports the synthesis of immunoglobulins.
- Vitamin E is a physiological antioxidant that protects cell membranes from damage, prevents hemolysis, stimulates the synthesis of many proteins, and has a positive effect on the function of the gonads and nervous tissue.
- Vitamin B1 is involved in carbohydrate metabolism and is necessary for the functioning of the nervous system.
- Vitamin B6 is involved in protein metabolism, without it the synthesis of neurotransmitters is not possible.
- Vitamin B2 is involved in cellular respiration and redox reactions.
- Vitamin B12 is a growth factor, is involved in the synthesis of amino acids, and is necessary for the processes of red blood cell maturation, hematopoiesis in general, and for the metabolism of folic acid.
- Folic acid is involved in the synthesis of amino acids and choline metabolism. It is necessary for the normal course of erythropoiesis and, together with vitamin B12, stimulates it.
- Rutoside is an antioxidant. Reduces capillary fragility, inhibits the effect of hyaluronidase. Promotes the accumulation of ascorbic acid in tissues.
- Nicotinamide takes part in tissue respiration, lipid and carbohydrate metabolism. It is part of the glucose tolerance factor.
- Vitamin C is necessary for the growth of bones, cartilage, skin, capillary endothelium, for the formation of hemoglobin and the maturation of red blood cells. Necessary for the functioning of the nervous system.
- Glutamic acid is a material for the synthesis of amino acids in the body. Improves protein and carbohydrate metabolism, energy supply to the brain. The presence of glutamic acid improves nervous activity and motor activity. Promotes the release of ammonia from the body.
- Methionine is an essential amino acid necessary for growth and the processes of detoxification of xenobiotics, activation of hormones, enzymes and proteins. Prevents fatty liver degeneration.
- Phytin is an organic phosphorus compound. Stimulates hematopoiesis, affects bone growth and helps improve the function of the nervous system.
- Calcium pantothenate is necessary for the synthesis of ATP and antibodies, the absorption of potassium and vitamin E. Participates in the processes of epithelial regeneration.
- Potassium is involved in electrolyte metabolism and nerve impulse transmission. Activates muscle work, including the heart muscle, regulates vascular tone.
- Copper is involved in anabolic processes, iron metabolism and the formation of red blood cells. Strengthens the walls of blood vessels.
Pharmacokinetics
Not studied.
Quadevit®
A complex preparation containing a complex of vitamins and minerals, which are important factors in metabolic processes. The dose of each vitamin is close to the physiological daily requirement.
Vitamin A (retinol acetate)
ensures the normal function of the skin, mucous membranes, and the organ of vision.
Vitamin E (α-tocopherol acetate)
has antioxidant properties, maintains the stability of red blood cells, prevents hemolysis; has a positive effect on the functions of the gonads, nervous and muscle tissue.
Vitamin B1 (thiamine chloride)
participates in carbohydrate metabolism and the functioning of the nervous system.
Vitamin B2 (riboflavin)
- the most important catalyst for the processes of cellular respiration and visual perception.
Vitamin B6 (pyridoxine hydrochloride)
takes part in protein metabolism and the synthesis of neurotransmitters.
Folic acid
takes part in the synthesis of amino acids, nucleotides, nucleic acids; necessary for normal erythropoiesis.
Rutoside (rutin)
participates in redox processes, has antioxidant properties, prevents oxidation and promotes the deposition of ascorbic acid in tissues.
Nicotines
d participates in the processes of tissue respiration, fat and carbohydrate metabolism.
Vitamin C (ascorbic acid)
ensures collagen synthesis; participates in the formation and maintenance of the structure and function of cartilage, bones, teeth; affects the formation of hemoglobin and the maturation of red blood cells.
Vitamin B12 (cyanocobalamin)
participates in the synthesis of nucleotides, is an important factor in normal growth, hematopoiesis and development of epithelial cells; necessary for folic acid metabolism and myelin synthesis.
Glutamic acid
takes part in nitrogen metabolism, being the starting material for amino acid synthesis in the body. Stimulates oxidative processes, improves protein and carbohydrate metabolism, improves energy supply to brain functions. The introduction of glutamic acid improves nervous activity, improves mood and motor activity.
Methionine
activates the action of hormones, vitamins, enzymes, proteins. Essential for detoxification of xenobiotics.
Calcium pantothenate
plays an important role in oxidative reactions; participates in the regeneration of epithelium and endothelium.
Fitin
stimulates hematopoiesis, enhances the growth and development of bone tissue; improves the function of the nervous system in diseases associated with a lack of phosphorus in the body.
Potassium
regulates the acid-base balance of the body. Participates in the processes of transmission of nerve impulses and muscle contraction, activates the work of a number of enzymes, activates the muscular work of the heart, and participates in the regulation of vascular tone.
Copper
participates in processes that provide tissues with oxygen: the formation of hemoglobin and the formation of red blood cells. Strengthens the walls of blood vessels.
Analogs
Level 4 ATC code matches: Optix
Antioxycaps
Multi-Tabs Immuno Kids
Multi-Tabs Immuno Plus
Multi-Tabs Active
Coenzyme Q10
Doppelhertz Energotonic
Complement for women 45 Plus
Vitamax
Revalid
Gerimaks
Biovital
Vitrum Lift-Skin Q10
Vitrum Vision
Vitrum Beauty
There is no vitamin complex that completely replicates the composition of Kvadevit. You can name an analogue of Kvadevit in action - Complivit , as well as Alvitil , Revit , Pangexavit .
Active components
- Ginkgo biloba leaf extract - stimulates blood circulation in both healthy and ischemic tissues of the heart and brain, counteracts platelet aggregation factor, preventing blockage of blood vessels; improves brain cell metabolism, nervous system activity, memory function and learning ability; improves blood circulation, regulates pressure in blood vessels; improves the functioning of the cardiovascular system.
- Vitamin A has a positive effect on the function of the lacrimal, sebaceous and sweat glands; increases resistance to diseases of the mucous membranes of the respiratory tract and intestines; increases the body's resistance to infections; stimulates skin regeneration; is a necessary component for normal retinal function.
- Vitamin C is a water-soluble antioxidant with a powerful restorative effect. Increases nonspecific resistance of the body.
- Vitamin E - prevents lipid peroxidation. Necessary for the biosynthesis of heme and proteins, tissue respiration processes, affects the tone and permeability of blood vessels.
- Rutin has a positive effect on the walls of blood vessels - strengthens them, promotes blood clotting, improves oxygen supply, and normalizes blood pressure. Improves metabolism, promotes effective fat processing and absorption of vitamins C and E.
- B vitamins (B1, B2, B3, B6 and B9) ensure the normal course of many types of metabolism, including energy. Important for the functioning of the nervous, digestive systems, cardiac activity and endocrine glands. Participate in growth processes. Improve liver function, promote insulin incretion. A deficiency or increased need for one of the B vitamins is usually accompanied by a deficiency of the other vitamins in this group, so they must be taken in combination.
- Selenium - helps neutralize and remove harmful and foreign substances, heavy metals (lead, mercury, cadmium) from the body; improves thyroid function; normalizes cholesterol metabolism; participates in the metabolic processes of the bone, cardiovascular, immune and digestive systems; has a positive effect on the condition of the hair.
- Zinc - participates in the implementation of the biological functions of insulin, normalizing fat metabolism, in hematopoiesis, and is also necessary for the normal functioning of the pancreas and seminal vesicles. Zinc protects the skin from dangerous free radicals and accelerates its regeneration process.
Reviews about Kvadevit
This vitamin complex is designed primarily for elderly people. It has a lipid-lowering effect: it reduces the atherogenic index and reduces cholesterol in patients with coronary artery disease . It is also used to prevent aging. Consumers note an acceptable price compared to imported drugs. Some people are not satisfied with the frequency of administration - three times a day, since they can forget about taking it.
Many people, including middle-aged people, take these vitamins to prevent diseases and speak positively about them.
“For the second winter in a row, I’ve been taking Kvadevit for preventive purposes—I’ve never gotten sick.”
“This is not the first time I’ve taken Kvadevit and I notice that there is an incredible increase in strength.”
“I noticed that after taking these vitamins my nails stopped peeling.”
However, vitamin complexes with a limited content of minerals ( Kvadevit Revit , Undevit ) have recently been losing popularity, as consumers have a tendency to purchase drugs with the maximum possible number of useful components - a full range of minerals and trace elements.
Kvadevit tablets, 60 pcs.
Vitamin A (retinol acetate) plays a key role in the synthesis of enzyme proteins and structural components of tissues, is necessary for the formation of epithelial cells, bones and rhodopsin synthesis, supports the division of immunocompetent cells, normal synthesis of immunoglobulins and other factors of protection against infections.
Vitamin E (α-tocopherol acetate) is a physiological antioxidant that protects cell membranes from damage and stimulates the synthesis of heme and many proteins.
Vitamin B1 (thiamine hydrochloride) is an important coenzyme in the metabolism of carbohydrates and takes part in the functioning of the nervous system.
Vitamin B2 (riboflavin) is part of the flavin coenzymes - flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which take part in redox reactions and is a catalyst for cellular respiration processes.
Vitamin B6 (pyridoxine hydrochloride) plays an important role in the metabolism of amino acids, neurotransmitters and hemoglobin.
Vitamin B12 (cyanocobalamin) is a growth factor, necessary for the normal course of hematopoiesis and red blood cell maturation, and takes part in the synthesis of amino acids, nucleic acids and myelin.
Nicotinamide is a component of the cofactor NAD(H) and NADP(H), part of the glucose tolerance factor, and takes part in the processes of tissue respiration, carbohydrate and lipid metabolism.
Folic acid is necessary for the normal formation of blood cells; together with vitamin B12, it stimulates erythropoiesis, takes part in the synthesis of amino acids, nucleic acids, and choline metabolism.
Vitamin C (ascorbic acid) takes part in redox processes and is necessary for the growth and formation of bones, skin, teeth, capillary endothelium and for the normal functioning of the nervous and immune systems.
Rutin reduces the permeability and fragility of capillaries, takes part in redox processes, and inhibits the action of hyaluronidase.
Calcium D-pantothenate is part of coenzyme A and is necessary for the normal functioning of the tricarboxylic acid cycle, the synthesis of adenosine triphosphate (ATP), the production of hormones and antibodies, the synthesis of acetylcholine, and the absorption of potassium ions, glucose, and vitamin E from the intestine.
Copper is an essential microelement that takes an active part in iron metabolism, hemoglobin synthesis, reticulocyte maturation, and anabolic processes.
Potassium takes part in electrolyte metabolism and conduction of nerve impulses.
Phytin is a complex organic phosphorus compound containing a mixture of calcium and magnesium salts of inositol phosphoric acids; stimulates hematopoiesis, enhances the growth and development of bone tissue, improves the function of the nervous system.
Glutamic acid takes part in metabolic processes, promotes the neutralization and release of ammonia, and stimulates the transmission of excitation in the synapses of the central nervous system. Methionine is an essential amino acid, necessary for growth and nitrogen balance in the body, takes part in the processes of remethylation and transsulfuration, and prevents fatty infiltration of liver cells.
Vitamins and microelements are contained in the medicine in physiological, balanced doses that meet the needs of the human body.
Kvadevita price, where to buy
At the moment, it is not possible to buy Kvadevit in Moscow pharmacies. If you are interested in domestic vitamin preparations that are affordable, then in the pharmacy chain you can buy Revit 100 tablets for 34-65 rubles. and Undevit 50 tablets for 45-66 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
LuxPharma* special offer
- Kvadevit tab.
N60 1800 rub. order
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Pharmacy24
- Kvadevit No. 30 tablets PAT "Kiev Vitamin Plant", Kiev, Ukraine
74 UAH. order - Kvadevit N60 tablets PAT "Kiev Vitamin Plant", Kiev, Ukraine
134 UAH order
SOCIAL PHARMACY
1 film-coated tablet contains: retinol acetate 0.00086 g (2500 IU), thiamine chloride 0.002 g or thiamine bromide 0.0032 g, riboflavin 0.0025 g, pyridoxine hydrochloride 0.002 g, cyanocobalamin 0.00001 g, ascorbic acid 0.075 g, alpha-tocopherol acetate 0.003 g, nicotinamide 0.02 g, rutin 0.01 g, folic acid 0.0001 g, calcium pantothenate 0.005 g, glutamic acid 0.05 g, methionine 0.05 g, phytin 0, 03 g, potassium chloride 0.02 g and copper sulfate 0.00156 g; 30 pcs in a polymer jar, 1 jar in a cardboard pack.INSTRUCTIONS
PHARMACOLOGICAL PROPERTIES:pharmacological properties
Vitamin A plays a key role in the synthesis of protein-enzymes and structural components of tissues, is necessary for the formation of epithelial cells, bones and the synthesis of rhodopsin, supports the division of immunocomponent cells, the normal synthesis of immunoglobulins and other factors of protection against infections. Vitamin E is a physiological antioxidant that protects cell membranes from damage and stimulates the synthesis of heme and many proteins. Vitamin B1 is an important coenzyme in the metabolism of carbohydrates and takes part in the functioning of the nervous system. Vitamin B2 is part of the flavin coenzymes - flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which take part in redox reactions and is a catalyst for cellular respiration processes. Vitamin B6 plays an important role in the metabolism of amino acids, neurotransmitters and hemoglobin. Vitamin B12 is a growth factor, necessary for the normal course of hematopoiesis and red blood cell maturation, and takes part in the synthesis of amino acids, nucleic acids and myelin. Nicotinamide is a component of the cofactor NAD(H) and NADP(H), part of the glucose tolerance factor, and takes part in the processes of tissue respiration, carbohydrate and lipid metabolism. Folic acid is necessary for the normal formation of blood cells; together with vitamin B12, it stimulates erythropoiesis, takes part in the synthesis of amino acids, nucleic acids, and choline metabolism. Vitamin C takes part in redox processes and is necessary for the growth and formation of bones, skin, teeth, capillary endothelium and the normal functioning of the nervous and immune systems. Rutin reduces the permeability and fragility of capillaries, takes part in redox processes, and inhibits the action of hyaluronidase. Calcium pantothenate is part of coenzyme A and is necessary for the normal functioning of the tricarboxylic acid cycle, ATP synthesis, production of hormones and antibodies, acetylcholine synthesis, absorption of potassium ions, glucose, vitamin E, etc. from the intestines. Copper, an essential microelement, takes an active part in metabolism iron, hemoglobin synthesis, reticulocyte maturation, anabolic processes. Potassium takes part in electrolyte metabolism and conduction of nerve impulses. Phytin is a complex organic phosphorus compound containing a mixture of calcium and magnesium salts of inositol phosphoric acids; stimulates hematopoiesis, enhances the growth and development of bone tissue, improves the function of the nervous system. Glutamic acid takes part in metabolic processes, promotes the neutralization and release of ammonia, and stimulates the transmission of excitation in the synapses of the central nervous system. Methionine is an essential amino acid, necessary for growth and nitrogen balance in the body, takes part in the processes of remethylation and transsulfuration, and prevents fatty infiltration of the liver. Vitamins and microelements are found in Kvadevit in physiological, balanced doses and correspond to the needs of the human body. The pharmacokinetics of the drug Kvadevit has not been studied.
INDICATIONS
the drug is indicated as a preventive and therapeutic agent: • to improve mental and physical performance in active age (18–55 years); • in case of hypovitaminosis, increased need of the body for vitamins due to an unbalanced diet, adherence to a special diet, intolerance to certain foods; •to meet the increased need for vitamins during the recovery period after serious illnesses, operations, injuries and stressful situations, radiation and chemotherapy, with a decrease in the body’s immune resistance; •to increase the overall resistance of the body and prevent infectious diseases during epidemics (influenza, etc.), seasonal exacerbations of chronic diseases; •in old age - to optimize metabolism and the functioning of the endocrine glands, prevent premature aging; •to stimulate the healing of wounds and burns; •in order to reduce toxicity and reduce the severity of side effects of drugs, enhance the functional activity of the liver; •in the complex treatment of atherosclerosis, cerebrovascular accidents and cardiovascular failure.
APPLICATION
the drug is taken orally after meals. For preventive purposes, Kvadevit is prescribed to adults and children over 14 years of age, 1 tablet per day, for elderly people - 1 tablet 2 times a day. The duration of the preventive course is 1–2 months. For therapeutic purposes, use 1 tablet 3 times a day. The course of treatment is 3–4 weeks. Repeated courses are carried out after a 3-month break. During pregnancy and breastfeeding, the drug is used exclusively as prescribed by a doctor. In the first trimester - no more than 1 tablet per day, in the second and third trimester - no more than 2 tablets per day. During breastfeeding, take 1 tablet per day for preventive purposes, and 1 tablet 2 times a day for therapeutic purposes.
CONTRAINDICATIONS
hypersensitivity to the components of the drug, children under 14 years of age.
SIDE EFFECTS
in recommended doses, the drug is well tolerated and rarely causes side effects, which are usually associated with individual intolerance to individual components. In this case, allergic reactions (itching, skin hyperemia, skin rashes) and gastrointestinal dysfunction are possible, requiring discontinuation of the drug. If these or any undesirable symptoms appear, the drug should be discontinued.
SPECIAL INSTRUCTIONS
The drug must be taken under medical supervision. When taking Kvadevit, like other multivitamin preparations, you need a complete protein diet that promotes better absorption and metabolism of vitamins, especially water-soluble ones. The urine may turn yellow, which is a completely safe symptom and is explained by the presence of riboflavin in the drug. It is not recommended to take Kvadevit simultaneously with other drugs that contain vitamins included in the drug (especially vitamin A), due to the possibility of developing overdose symptoms. Use during pregnancy and lactation. The drug is used exclusively as prescribed by a doctor, without exceeding the recommended dose. Children. This dosage form is not intended for use in children under 14 years of age. The ability to influence reaction speed when driving vehicles or working with other mechanisms. There is no data on the effect of the drug on the ability to drive a car or operate complex machinery.
INTERACTIONS
The interaction of Kvadevit with other drugs has not been described. While using the drug, you should not take other vitamin preparations due to the possibility of developing hypervitaminosis.
OVERDOSE
no cases of overdose of the drug Kvadevit have been reported. In case of overdose, allergic reactions (itching, skin hyperemia, skin rashes) and gastrointestinal dysfunction may occur. Treatment: discontinue the drug, symptomatic therapy.
STORAGE CONDITIONS
in original packaging at a temperature not exceeding 25 °C.
Before using the drug Kvadevit, you should consult your doctor. This instruction is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions.
