Hexoral: what it treats and when to take it

Hexoral tabs classic

Hexoral tabs - available in the form of lozenges with the taste of lemon with honey, blueberry and orange. The main active ingredient is amylmetacresol. Being an anesthetic, it successfully fights pathogenic flora that causes sore throat, cough, and irritation of the mucous membrane.

During resorption, the substances are slowly dissolved by saliva and gently envelop the oral cavity and tonsils, descending down the trachea. Regular use of medicinal lozenges allows you to destroy the pathogen, regardless of what type of microorganism caused the disease.

It is recommended to dissolve the tablets after meals so that the medicinal effect is not washed away with drinks and food. Within an hour after resorption, you should not drink or eat.

Hexoral aerosol

The active ingredient in Hexoral aerosol is hexetidine. It is an antiseptic that prevents the oxidative reactions of bacteria necessary for metabolism. This is how its antimicrobial effect manifests itself. In addition, Hexoral in spray form is also active against fungi that cause candidiasis.

Hexoral aerosol for topical use 0.2%, 40 ml

Manufacturer

Famar Orleans, France

Briefly about the product

“Spray Hexoral® can act on 4 main causes of sore throat - bacteria, viruses, fungi and biofilms 1. 1 – Polyakova A.S., Tatochenko V.K. Once again about the term “viral-bacterial infection”. Medical advice. 2015;(14): 30-35."

Compound

100 ml of the drug contains: active ingredient: hexetidine – 0.200 g; excipients: polysorbate 80 - 1.400 g, citric acid monohydrate - 0.070 g, sodium saccharinate - 0.040 g, levomenthol - 0.070 g, eucalyptus leaf oil - 0.0011 g, sodium calcium edetate - 0.100 g, ethanol 96% - 4.333 g , sodium hydroxide – qs up to pH 5.5 ± 0.2, purified water – qs up to 100 ml, nitrogen – qs up to 5 bar.

Clinical pharmacology

Pharmacodynamics: The antimicrobial effect of the drug "Hexoral®" is associated with the suppression of oxidative reactions of bacterial metabolism (thiamine antagonist). The drug has a wide spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, however, Hexoral® can also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus spp. At a concentration of 100 mg/ml, the drug inhibits most strains of bacteria. No development of resistance was observed. Hexethidine has a weak anesthetic effect on the mucous membrane. The drug has an antiviral effect against influenza A viruses, respiratory syncytial virus (RS virus), and herpes simplex virus type 1, which affect the respiratory tract. Pharmacokinetics: Hexetidine adheres very well to the mucous membrane and is practically not absorbed. After a single use of the active substance, traces of it are found on the gum mucosa within 65 hours. In dental plaque, active concentrations remain for 10–14 hours after application.

Indications

As a symptomatic remedy. • Symptomatic treatment for inflammatory and infectious diseases of the oral cavity and larynx: – tonsillitis, tonsillitis (including Plaut-Vincent tonsillitis, tonsillitis of the lateral ridges), pharyngitis, gingivitis, stomatitis, glossitis, periodontal disease; – fungal diseases; • prevention of infectious complications before and after surgical interventions on the oral cavity and larynx and in case of injuries, including prevention of infection of the alveoli after tooth extraction; • oral hygiene, including to eliminate bad breath.

Use during pregnancy and breastfeeding

There is no information about any undesirable effects of the drug Hexoral® during pregnancy and breastfeeding. However, before prescribing Hexoral® to pregnant or lactating women, the doctor must carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placenta and into breast milk.

Contraindications

• Hypersensitivity to any of the components of the drug; • erosive-desquamous lesions of the oral mucosa; • children under 3 years of age.

Side effects

Adverse reactions identified during post-registration use of the drug were classified as follows: very common (≥1/10), common (≥1/100, <1/10), not common (≥1/1000, <1/100) , rare (≥1/10000, <1/1000), very rare (<1/10000), frequency unknown (incidence cannot be estimated based on available data). Immune system disorders. Very rare: hypersensitivity reactions (including urticaria), angioedema. Nervous system disorders. Very rare: ageusia, dysgeusia. Disorders of the respiratory system, chest and mediastinal organs. Very rare: cough, shortness of breath due to a hypersensitivity reaction. Gastrointestinal disorders. Very rare: dry mouth, dysphagia, nausea, enlarged salivary glands, vomiting. General disorders and disorders at the injection site. Very rare: application site reactions (including irritation of the oral mucosa and pharynx, burning sensation, oral paresthesia, discoloration of the tongue, discoloration of the teeth, inflammation, blistering and ulceration). If any of the side effects listed in the instructions get worse or you notice other side effects, it is recommended to consult a doctor.

Interaction

No data available.

How to take, course of administration and dosage

Locally. Children from 3 to 6 years old: use of the drug is possible after consultation with a medical professional. Adults and children over 6 years of age: treat the affected areas while holding your breath, 1 injection for 1-2 seconds 2 times a day. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals. General recommendations for administration. The drug is sprayed into the mouth or throat. Using an aerosol you can easily and quickly treat the affected areas. It is necessary to perform the following steps: • put the spray nozzle on the aerosol can; • direct the end of the spray nozzle to the affected area of the mouth or pharynx; • during the administration of the drug, the bottle should be kept in a vertical position at all times, as shown in the figure; • inject the required amount of the drug by pressing on the head of the spray nozzle for 1–2 seconds, do not breathe while administering the aerosol. The duration of treatment is determined by the doctor.

Overdose

It is unlikely that hexetidine can have a toxic effect when used according to the instructions for use of the drug. Ingestion of large quantities of a product containing ethanol may result in signs/symptoms of alcohol intoxication. In any case of overdose, consult your doctor immediately. Treatment is symptomatic, as for alcohol intoxication. Gastric lavage is necessary within 2 hours after ingestion of an excess dose.

Special instructions

There are no special instructions.
Use in pediatrics

In children, the drug can be used from an age when there is no danger of uncontrolled swallowing or when they do not resist a foreign object (spray nozzle) in the mouth when using an aerosol and are able to hold their breath when injecting the drug.

Impact on the ability to drive vehicles and operate machinery

Hexoral® aerosol does not affect the ability to drive vehicles and other potentially hazardous activities.

Rules for drug disposal

The patient should be informed that if the medicine has become unusable or has expired, it should not be thrown into wastewater or onto the street. It is necessary to place the medicine in a bag and place it in the trash container. These measures will help protect the environment.

Release form

Aerosol for topical use

Storage conditions

Store at a temperature not exceeding 25 °C. Keep out of the reach of children.

Best before date

2 years

Active substance

Hexethidine

Dosage form

mouth spray

Purpose

Pregnant women in the 2nd and 3rd trimester as prescribed by a doctor, For adults, Children over 3 years old, Pregnant women as prescribed by a doctor, Nursing mothers as prescribed by a doctor

Indications

Sore throat, Tonsillitis, Thrush, Periodontitis, Stomatitis, Pharyngitis, Periodontitis, Inflammation in the oral cavity, Colds, Inflammation of the gums, Flu

Barcode and weight

Barcode: 3574661065885 Weight: 0.073 kg

How much does Hexoral rinse solution cost?

Hexoral solution is used exclusively for rinsing the mouth. The drug should not be swallowed, therefore, if the patient, due to age or some other characteristics, cannot spit out liquid that has entered the mouth, the form of mouthwash is not suitable for such patients.

Rinsing with Hexoral is effective not only for pain or inflamed tonsils, but also for stomatitis or inflammation of the gums.

The drug is sold in aerosol form at pharmacies. No doctor's prescription required. The average cost of one bottle is 300 rubles.

Description and composition

The active ingredient of the drug is hexetidine.

The drug is available in several forms:

aerosol;
solution.

The most popular is an aerosol, which is widely used for various throat diseases. The active substance is an antiseptic and affects many harmful bacteria, as well as Candida fungi.

Has a slight analgesic effect. The therapeutic effect can last up to fourteen hours.

Is it possible to take Hexoral for purulent sore throat?

Sore throat is an infectious disease caused by a bacterium called streptococcus. Streptococci are gram-positive bacteria that are susceptible to destruction by Hexoral. For purulent sore throat, local exposure to an antiseptic will not be a mistake; this will allow you to quickly restore the healthy state of the mucous membranes.

However, a sore throat, regardless of whether it is purulent or not, cannot be treated only with local drugs. Hexoral should act as an additional therapy, in combination with a systemic antibiotic. Delaying treatment and refusing to take antibacterial drugs orally can lead to complications from the cardiovascular system and the musculoskeletal system.

When is it prescribed?

The drug is useful in the following conditions:

for infections of the mouth and throat;
tonsillitis;
angina;
pharyngitis;
gingivitis;
bleeding gums;
aphthous ulcers;
stomatitis;
glossitis;
conditions after tooth extraction;
before and after throat surgery;
prevention of mouth and throat infections;
with thrush of the mouth and throat;
cold;
ARVI;
Flu.

The drug is also used to minimize bad breath in people with tooth decay or stomach problems.

Is it possible to use Hexoral for a dry cough?

A dry cough indicates that the mucous membrane of the respiratory tract is inflamed. Any dry cough needs to be made wet, that is, productive. Only a wet cough can remove harmful substances from the respiratory tract. This will significantly speed up the healing process. The only exception is an allergic dry cough, which is not related to pathogenic flora in the sputum.

The use of Hexoral does not have a mucolytic or expectorant effect. However, the use of lozenges provokes greater secretion of saliva, due to which the mucous membranes are moistened and the cough can become wet.

Despite the lack of mucolytic effect, Hexoral is also indicated for dry cough. This is explained by the fact that cough is only a symptom, not a diagnosis. It is the disease that needs to be treated, not the cough. Hexoral, having an antiseptic effect, successfully destroys the source of infection in the throat.

special instructions

Local antiseptics do not play a big role in the treatment of acute manifestations of any respiratory diseases. The use of such drugs is important mainly when the patient feels the beginning of a sore throat. At the initial stages of the spread of infection, Hexoral is able to suppress the pathogen and prevent the infection from spreading and becoming acute.

If the use of the drug does not produce positive dynamics within 7 days, you must stop self-medication and seek qualified help.