Hofitol is a medicinal product that is made from the field artichoke. The drug has hepatoprotective and choleretic effects. It uses natural ingredients as additional ingredients. Due to this, the risks of side effects when using it are minimal.
Compound
One Hofitol tablet contains 200 mg of dried aqueous extract of Cynara Scolymus (field artichoke) leaves, as well as pregelatinized corn starch - 22 mg, talc - 3 mg, magnesium trisilicate - 12 mg, magnesium stearate - 3 mg. Shell composition: talc - 16.3 mg, rosin - 1.152 mg, gum lac - 1.152 mg, sucrose - 86.146 mg, gelatin - 0.384 mg, calcium carbonate - 2.2 mg, carnauba wax - 0.082 mg, polysorbate 80 - 0.004 mg, dispersed dye (oxides brown, black and yellow, sucrose), additives E214 and E 218 (ethyl and methyl parahydroxybenzoate).
The composition of the Hofitol solution includes a thick aqueous extract of Cynara Scolymus (field artichoke) leaves at a concentration of 20 g per 100 ml, ethyl alcohol, orange flavor, methyl parahydroxybenzoate, propyl parahydroxybenzoate, glycerol, purified water.
Pharmacodynamics and pharmacokinetics
The medicine Hofitol - its effect?
The pharmacological properties of the drug are due to the action of the complex of biologically active substances contained in the leaves of Cynara Scolymus. Cynarin in combination with phenolic acids has hepatoprotective and choleretic effects. Carotene, inulin, ascorbic acid and vitamins B1 and B2 help normalize metabolic processes.
Hophytol helps to activate bile formation and excretion, reduce the level of urea and cholesterol in the blood.
Pharmacokinetics
Carrying out kinetic observations and identifying metabolites of the drug is not possible, since the effect of Hofitol is the cumulative effect of its active substances.
What is Hofitol taken for?
Medicine in any form is prescribed for the following conditions and diseases:
- dyspeptic disorders, which are accompanied by nausea, vomiting, bloating, and indigestion;
- chronic hepatitis;
- cirrhosis of the liver;
- chronic renal failure;
- non-calculous cholecystitis.
In combination with other drugs with the same active substance, it can be used for the following problems:
- excessive weight;
- anorexia;
- atherosclerosis;
- urolithiasis.
Indications for use of Hofitol
Injection solution, drops and tablets Hofitol - what are they for?
Indications for use of Hofitol:
- dyspeptic disorders, manifested by nausea, flatulence, heartburn, a feeling of heaviness in the epigastric region;
- chronic non-calculous (calculous) cholecystitis;
- chronic hepatitis;
- biliary dyskinesia (BDH) of the hypokinetic type (characterized by slowing and sluggishness of bile outflow);
- cirrhosis of the liver;
- chronic renal failure;
- chronic nephritis.
In combination with other drugs, field artichoke preparations can be used to treat:
- chronic intoxication (salts of heavy metals, alkaloids, nitro compounds, hepatotoxic substances);
- anorexia;
- obesity;
- atherosclerosis;
- uraturia;
- urolithiasis.
Indications for use and therapeutic effect
Most often, Hofitol is prescribed for the treatment of diseases that damage the gallbladder and liver. Thanks to the medication, the flow of bile is restored. The course of treatment with Hofitol is up to 2 months. After a 2-3 month break it can be repeated. Three authorized courses of therapy per year guarantee effective therapy. By maintaining high-quality bile outflow, the patient's condition quickly improves. The product protects the liver from overload and helps eliminate intoxication.
The drug is also prescribed for various dyspeptic problems. It is used in complex therapy of chronic hepatitis and liver cirrhosis. The drug is indicated for stabilizing the body condition of patients with non-calculous cholecystitis and chronic renal failure.
In combination with other drugs, Hofitol is prescribed for excessive weight or anorexia. It improves the effectiveness of treatment of atherosclerosis and urolithiasis. After taking the medicine, an anti-inflammatory effect is provided and metabolism is normalized.
Contraindications
The drug is not prescribed in case of known hypersensitivity to the components of the tablets/solution (in particular to preservatives E214, E216 or E218) and plants of the aster family (Asteraceae or Compositae).
Other contraindications to the use of Hofitol:
- bile duct obstruction;
- cholelithiasis;
- acute diseases of the kidneys, liver, urinary and biliary tract ( angiocholitis , empyema of the gallbladder , etc.);
- children up to six years of age (for the tablet form of the drug).
Contraindications and side effects
It is strictly prohibited to take Holyfill in combination with alcohol in the presence of serious pathologies, such as:
- Chronic renal and liver failure.
- Obstruction of the bile ducts.
- Any damage to the gallbladder and digestive system organs.
A contraindication is individual intolerance to the components included in the medicine. Despite the naturalness of the drug, there is a health hazard in case of overdose. If the doctor's recommendations and instructions for use are violated, life is threatened.
When consuming Holyfill with alcohol simultaneously, the likelihood of side effects increases:
- Dizziness.
- Diarrhea.
- Nausea
- Vomiting.
In severe cases, increased blood pressure, allergies and difficulties with coordination of movements may occur.
Instructions for use of Hofitol (Method and dosage)
Hofitol tablets, instructions for use
Patients over the age of twelve are prescribed to take tablets three times a day (before meals), one or two tablets at each dose (daily dose from 600 mg to 1.2 g).
Treatment usually lasts from 2 to 3 weeks. If necessary, the doctor may prescribe a repeat course.
Hofitol solution, instructions for use
The oral solution is shaken and diluted with water before use. A single dose for an adult is 2.5 - 5 ml (1 tsp). Frequency of applications - 3 times a day.
The duration of treatment depends on the nature and characteristics of the course of the disease.
special instructions
- Hofitol should be used with extreme caution in pathologies that could potentially provoke bile duct obstruction , as well as in severe liver pathologies .
- The occurrence of abdominal pain and/or diarrhea should be a reason to stop treatment and consult a doctor.
- The tablets contain sucrose (0.08 grams/tablet), which should be taken into account in patients with glucose-galactose malabsorption syndrome , fructose intolerance or sucrase-isomaltase deficiency .
- The presence of preservatives in tablets and oral solution may cause the development of hypersensitivity reactions (including delayed ones).
- The oral solution contains ethanol, therefore, during treatment with Hofitol in this dosage form, it is recommended to avoid drinking drinks that contain alcohol.
- Tablets and injection solution do not slow down the speed of reactions and do not impair the ability to concentrate. Drops for oral administration, due to the presence of ethanol in their composition, can affect these parameters, which should be remembered when driving a car and when working with machinery.
Combination with alcohol
Considering the fact of a long course of treatment with Hofitol, in the treatment of various pathologies, many are interested in the question of the compatibility of the drug with alcoholic beverages. In order to understand this, you need to know how alcohol enters the blood. Part of the process begins in the stomach and intestines. But at the same time, the most dangerous components are filtered out by the liver. This increases the load on the organ.
With alcohol abuse, pathological abnormalities occur in the liver. The following symptoms indicate this:
- Bitterness in the mouth.
- Temperature increase.
- Cutting pain in the organ area.
- Constant heaviness in the right side.
When Chofitol and alcohol are combined, the load on all internal organs increases. First of all, malfunctions of the liver may occur. With a strong negative impact, the likelihood of developing liver failure, cirrhosis, etc. increases. Against the background of severe liver pathologies, when taking Chofitol with alcohol simultaneously, there is a risk of death
Removing alcohol intoxication
The drug Hofitol is often prescribed for alcohol intoxication. During treatment, drinking alcoholic beverages is strictly prohibited. During therapy, the drug restores liver cells, but ethyl can aggravate the condition. With repeated treatment, the pharmacological effect of Hofitol is always less effective.
Medicine to eliminate alcohol intoxication is allowed to be taken after a feast no less than 12 hours later. Hofitol will accelerate the removal of breakdown products from the blood and protect the liver from their effects. If you take the medicine immediately after drinking alcohol, the risk of negative reactions in the body that worsen the person’s condition increases significantly. It is important to understand that Hofitol is an additional remedy for relieving alcohol intoxication, and not the main one. Therefore, in severe cases, gastric lavage should be performed and a drip should be used.
Hofitol's analogs
Similar drugs with a similar mechanism of action: Allohol , Arnica tincture , Berberine , Hepabene , Convaflavin , Leptandra , Olimethin , Tansy flowers , Choleretic collection , Tanacehol , Phytohepatol No. 2 and No. 3 , Flamin , Holagol , Holemaks , Holos , Holosas , Kavechol , Tsikvalon , Rosehip fruits .
A cheap analogue of Hophytol based on the leaf extract of Cynara Scolymus - dragees and tablets for the liver of Artichoke extract (about 220 rubles for package No. 60),
Which is better: Allohol or Hofitol?
Allohol , like Hofitol, is intended for the treatment of pathologies of the liver and biliary tract. Its basis is Activated carbon (enterosorbent), bile, garlic bulbs and stinging nettle leaves.
The drug has choleretic properties (has a cholekinetic effect and causes a moderate choleretic effect), enhances the secretory function of the liver, reflexively increases the motor and secretory organs of the digestive system, improves the digestion process in general and, in particular, the emulsification of dietary fats, reduces the likelihood of cholesterol precipitation from subsequent stone formation.
The active components of Allochol also help to inhibit fermentation processes in the intestinal tract and thereby reduce flatulence.
Allochol is prescribed for the treatment of cholangitis , chronic reactive hepatitis , ADHD , postcholecystectomy syndrome , and atonic constipation .
Choleretic drugs are prescribed only in the absence of signs of inflammation. The choice in favor of a particular drug is made taking into account the type of dysfunction, as well as depending on how quickly you need to get a positive result from therapy.
Both Allohol and Hofitol are true choleretics, since both increase the secretion of bile and stimulate the formation of bile acids, however, in addition to the choleretic effect, Hofitol also has a protective effect.
Based on this, we can conclude that the use of bile-containing drugs is advisable when it is necessary to carry out long-term course treatment for biliary dysfunction , while the choice in favor of Hofitol is made in situations where the patient is simultaneously diagnosed with liver pathology.
Which is better: Allohol or Hofitol
These two drugs can cope with diseases of the liver and biliary tract. Allochol contains activated carbon, bile, and garlic bulbs.
The medicine has a choleretic effect and has a positive effect on the functioning of the liver and gastrointestinal tract. Also, under the influence of active elements, flatulence decreases.
The difference is that Hofitol additionally has a protective effect.
It is advisable to take the drug Allochal for long-term therapy for biliary dysfunction. Hofitol should be used if the patient also has liver disease.
The use of Hofitol in pediatric practice
In pediatrics, solutions for oral/parenteral use are prescribed without age restrictions, tablets are prescribed to children over six years of age.
Indications for use in children are acute or chronic hepatitis , acalculous chronic cholecystitis , fatty hepatosis , motility disorders and decreased tone of the gallbladder and its ducts, increased concentration of acetone in the blood, intoxication (salts of heavy metals, nitrates, etc.), oliguria , chronic renal failure , chronic nephritis , skin diseases ( acne in adolescents, psoriasis , etc.), dyspeptic disorders, obesity, neonatal jaundice.
Children over twelve years of age are prescribed tablets at the same dose as adults. The daily dose of Hofitol tablets for children 6-12 years old is 600 mg (the dose should be divided into three doses).
The optimal dosage form for newborns is drops. According to the instructions for Hofitol, for newborns it is necessary to measure 5-10 drops of the medicine for each dose. The medicine is given on an empty stomach 3 times a day. Before giving the child Chofitol in drops, the required dose is first dissolved in 5 ml of water.
For adolescents over twelve years of age, 2.5-5 ml of solution is diluted in 1 tbsp. l. water. For children under twelve years of age, take 2-3 (depending on age and indications) milliliters of the drug for the same volume of water. The indicated dose should be taken 3 times a day. 20 minutes before meals.
Reviews of Hofitol for children indicate that the drug not only copes with its task very well, but is also very well tolerated by young patients. In addition, the drug is very convenient to use and easy to dose, which is very important when it comes to treating infants.
physiological jaundice for a long period .
An excessive increase in the concentration of bilirubin in the blood during pathological jaundice is dangerous because it can lead to the development of non-infectious damage to brain structures .
Timely use of Hofitol for newborns helps normalize liver function and biotransformation of insoluble toxic indirect bilirubin into non-toxic direct bilirubin. Mothers of young children note that bilirubin decreased on average by the ninth day of life, and by the end of the second or third week, the symptoms of jaundice completely disappeared.
Chofitol during pregnancy
Why is the drug prescribed to pregnant women?
What is Chofitol for during pregnancy? The instructions indicate that the use of Hofitol in pregnant women is allowed as prescribed by a doctor and provided that the expected result of treatment exceeds the likely risks to the fetus or child.
In the first months of pregnancy, the drug is prescribed for existing risk factors to prevent late gestosis , as well as to alleviate the condition of a woman with early toxicosis . There is evidence that the inclusion of Hofitol in the treatment regimen for preeclampsia helps to improve the clinical course of the disease.
During pregnancy, the drug acts as an antioxidant and hepatoprotector . It reduces the oxidative degradation of lipids under the influence of free radicals, improves fat metabolism, protects the liver and facilitates its work, stimulates the formation and excretion of bile, has a mild diuretic effect, reduces cholesterol in the blood, improves blood condition and blood microcirculation (including in the placenta) .
Despite the fact that the drug is not a special gynecological or obstetric drug, it is used to improve the condition of liver pathologies , atherosclerosis , and inflammatory diseases of the urinary tract.
The use of Hofitol also improves the general well-being of asthenic pregnant women. A woman is much less likely to be bothered by weakness, dizziness, mood swings, drowsiness, and her central nervous system excitability decreases.
One of the problems of pregnant women is fluid retention in the tissues. As a result, pregnancy is often complicated by quite serious pathologies. Chophytol improves the functioning of small vessels and kidney function, thus preventing the development of edema and dropsy.
However, it must be borne in mind that the drug does not have antiseptic and antibacterial properties. Therefore, if a blood test reveals signs of inflammation, Hofitol alone is not enough. Along with it, you should take uroseptic drugs .
Reviews about Chofitol during pregnancy are often good. Most women claim that the drug helped them well with toxicosis, heartburn and swelling. However, there are also reviews that note that the result was not noticeable even after completing the full course.
What dosage is considered optimal during pregnancy?
How to take Hofitol during pregnancy? The optimal dosage of tablets during pregnancy is 500 mg/day. The medicine is usually taken for three weeks.
In the form of an oral solution, Hofitol is taken three times a day, a teaspoon (5 ml). The course of treatment is usually about two weeks.
The duration of the course is determined by the doctor individually.
Use of Chofitol during lactation
Data on the safety of use of the product during breastfeeding are not provided.
Why take Hofitol during pregnancy?
You can take the drug only after examination by a doctor and his prescription. It is prescribed in the first trimester in order to prevent complications in the later stages, as well as to improve well-being in case of toxicosis in the early stages.
During the period of bearing a child, the drug has a positive effect on the liver, promotes the excretion of bile, has a mild diuretic effect, reduces the amount of cholesterol in the plasma, and has a positive effect on blood circulation. In addition, the medicine contributes to a general improvement in the condition, malaise and lethargy disappear, and mood improves.
Reviews about Khofitol
Hofitol is intended to enhance the motility of the gallbladder and restore normal bile flow in case of dysfunctional disorders of the biliary tract .
The drug has hepatoprotective and diuretic properties, which makes it possible to use it not only for ADHD and chronic pathologies such as nephritis , hepatitis or cholecystitis , but also during pregnancy (to reduce the severity of symptoms of early toxicosis and treat late gestosis ), for neonatal jaundice and for weight loss as part of obesity treatment programs (as an adjuvant).
If we study the reviews of doctors about Chofitol, we can conclude that the drug is effective for chronic cholecystitis and, in addition, “works” well for liver dysfunction. As a hepatoprotector , the drug is most often used to eliminate the consequences of toxic liver damage (including drug-induced).
Reviews of Hofitol for toxicosis , as well as the results of a number of studies confirm that after a course of use of the drug, the symptoms of toxicosis completely cease in approximately 25% of patients, and in another 35-50% (according to various sources), the general condition noticeably improves.
The forums also often discuss the feasibility, safety and effectiveness of prescribing Hofitol for children (in particular, for newborns). For older children, the medicine is prescribed for the treatment of diseases of the biliary tract and gall bladder, as well as for the elimination of dyspeptic symptoms , and for newborn children - for the treatment of physiological jaundice .
Most mothers leave good reviews about the drug, since it has a natural composition, is well tolerated by children and is easy to use. However, there are also reviews that mention side effects during treatment (the cause of complaints is most often diarrhea), and also that in some cases the medicine did not alleviate the child’s condition at all.
To be fair, it is worth noting that negative reviews about Hofitol are rare. Mostly they are left by people who are dissatisfied with the fact that the medicine did not completely rid them of the disease, but only temporarily removed the symptoms.
Hofitol price, where to buy
How much do tablets and solution cost in Russian pharmacies?
The price of Chofitol in drops is 500 rubles. You can buy tablets from 390 rubles for package No. 60 and from 890 rubles for package No. 180. The cost of the oral solution is 390-400 rubles.
Cost of Hofitol in Ukraine
The price of Hofitol in tablets is from 120 to 300 UAH (for 2 blisters of 30 tablets, 5 blisters of 12 tablets or 6 blisters of 10 tablets). Buy syrup in Kyiv, Odessa, Dnepropetrovsk and other large cities - 230 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Hofitol tablets p.p.o.
60 pcs. Rosa-Phytopharm 406 rub. order - Hofitol tablets p.p.o. 180 pcs Rosa-Phytopharm
902 rub. order
- Hofitol solution internal 120ml n1Rosa-Phytopharm
540 rub. order
Pharmacy Dialogue
- Hofitol (tab.p/vol. No. 60)Lab. Rosa-Phytopharma
400 rub. order
- Hofitol (tab. p/o No. 180)Lab. Rosa-Phytopharma
RUB 897 order
- Hofitol (oral solution 120 ml)Lab. Rosa-Phytopharma
RUR 543 order
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Pharmacy24
- Chophytol 120 ml No. 1 solution Laboratory Rose-Fitofarm, France
205 UAH order - Hofitol No. 180 tablets of the Rose-Phytopharma Laboratory, France
329 UAH. order
- Hofitol No. 60 tablets Laboratories Rosa-Phytopharma, France
113 UAH order
PaniPharmacy
- Hofitol tablets Hofitol tablets. p/o 0.2g No. 60 France, Lab. Rosa-Phytopharma
118 UAH order
- Hofitol tablets Hofitol tablets. p/o No. 180 France, Lab. Rosa-Phytopharma
341 UAH. order
- Hofitol liquid Hofitol solution per/approx. 120ml France, Lab. Rosa-Phytopharma
201 UAH order
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