Many people often have to resort to the use of medications to eliminate skin problems. Currently, pharmacies can provide a large number of special medications, the action of which is aimed at eliminating acne.
One of the most frequently used is Baziron AS, instructions for use of which are included in the package. The instructions require detailed reading to reduce the risk of side effects and overdose.
Baziron AC gel
The drug Baziron AS was developed by specialists to quickly and effectively eliminate problems that tend to form on oily skin and in the event of a malfunction in a person’s hormonal balance.
The action of Baziron AS is aimed at combating all types of defects, including acne.
The medicinal gel Baziron AS is used to reduce inflammatory processes, as well as to clean pores of bacteria that form due to the accumulation of fat.
Regular use of the product penetrates deeply into the layers of the epidermis and eliminates the causes of acne in the initial stages. Also, the effect of the drug allows you to normalize the secretion of sebum and reduces the shine of the skin.
Baziron AS is very often prescribed by specialists for patients who suffer from skin defects due to hormonal imbalances.
Composition and release form
The drug Baziron AS is available in the form of a gel, which spreads evenly over the skin and has a therapeutic effect.
In addition to the gel skin treatment, you can purchase the following forms of the product:
- Lotion for cleansing the face of sebum Baziron AS;
- Cleanser Baziron AS;
- Scrub for deep cleaning Baziron AS;
- Cream Baziron AC.
The drug has the following composition:
- Benzoyl peroxide;
- Glycerol;
- Acrylate copolymer;
- Carbomer;
- Poloxamer;
- Silicon;
- Purified water;
- Propylene glycol;
- Sodium hydroxide.
However, the most penetrating component is benzoyl peroxide.
Gel for the treatment of problem skin is available in the following forms:
- Gel for external use 2.5%;
- Gel for external use 5%;
- Gel for external use 10%.
Baziron: reviews of dermatologists about the drug
As we said above, reviews of Baziron AS from dermatologists allow us to deservedly classify this drug as the gold standard for the treatment of acne.
But, only as part of complex therapy! International protocols for the treatment of acne are well described in the most famous textbook on dermatology - Fitzpatrick's Dermatology (we use the 8th edition). What does this textbook tell us? 1) We have already said that acne can be of 2 types. Firstly, these are papules (without pus inside), and secondly, they are pustules with pus. A patient may have both types of acne well expressed at the same time, or one type may dominate the other. And this is very important for us, because... When prescribing a treatment regimen, we will take into account what type of inflammatory elements dominates in the patient.
2) If the patient is dominated by papules, then we will prescribe him the drug Baziron AS once a day (in the morning) + one of the topical retinoids based on adapalene. For example, it could be Differin or Clenzit (optional). Topical retinoids are also used externally once a day, but at night (24stoma.ru).
3) If the patient has pustules with pus, then this is a clear indication for using not only the combination of “benzoyl peroxide + topical retinoid”, but also adding an antibiotic. For mild to moderate severity, the antibiotic is prescribed externally; for severe acne, it is prescribed orally. Thus, for mild to moderate severity, we must use a combination of drugs. And here there are many possible combinations of different drugs.
For example, we can still use the drug Baziron AS 1 time a day (in the morning) + the drug Klenzit-S in the evening (it contains the retinoid adapalene + the antibiotic clindamycin). Another option may involve the use not of Baziron, but of combination drugs where benzoyl peroxide is combined with antibiotics or retinoids. Examples of combination drugs for acne treatment:
- Indoxyl (UK) – benzoyl peroxide 5% + clindamycin 1%.
- Effezel (France) – benzoyl peroxide 2.5% + retinoid adapalene 0.1%.
Those. we can, for example, use the combination drug Indoxyl once a day (in the morning), and in the evening use one of the topical retinoids (Differin or Clenzit - to choose from). Another option is that we can use the combined drug Effezel once a day (in the evening), but in the morning of that day we then have to use one of the antibiotic gels - it could be Dalatsin, Clindavit or others. As you can see: the abundance of different drugs gives us room for maneuver.
Important: But we want to assure you that acne treatment is not limited to just prescribing benzoyl peroxide, topical retinoids or antibiotics. Phototherapy, laser treatment, and in women, oral contraceptives to reduce the production of androgens can play a major role in treatment. You can read about all these methods using the links below.
→ International acne treatment protocols → Acne treatment protocols
Indications for use
Experts recommend using the drug to eliminate the following problems:
- Rosacea;
- Acne;
- Pimples with purulent formations;
- Acne;
- Black dots;
- Spots after acne removal;
- Comedones;
- Internal acne;
- Disruption of the sebaceous glands;
- Acne vulgaris;
- Hormonal skin rashes;
- Seborrheic dermatitis.
Depending on the problem that needs to be eliminated, specialists prescribe a certain type of Baziron AS gel.
Indications for use of the drug Baziron:
According to the instructions, it has only 1 indication for use:
- acne.
But the fact is that the indications in the official instructions for use are written incorrectly. The fact is that the term acne can imply the presence of only non-inflammatory elements - acne vulgaris (comedones). Such non-inflammatory elements do not require the use of antimicrobial agents, but are treated only with topical retinoids (Differin, Klenzit) or drugs with azelaic acid (Skinoren, Azelac).
Preparations with benzoyl peroxide are used when there are inflammatory elements (acne). The latter can be either in the form of pustules with pus, or papules without pus. Therefore, the correct indication for the use of Baziron should be “Papulopustular acne of mild, moderate or severe degree.”
Mechanism of action
The medicine is used only for external application.
The active components of the substance tend to penetrate deeply into the layers of the epidermis and turn into benzoic acid.
The action of this type of substance eliminates the causes of inflammatory formations and has a therapeutic effect on the skin.
Proper use allows you to eliminate bacteria that form in the pores due to the large secretion of sebum.
Benzoyl peroxide blocks further damage to healthy areas of the epidermis, and starts the natural process of restoration of cell membranes.
The action of the active components removes dead cells, which very often clog the pores of the epidermis and contribute to the appearance of blackheads and acne.
Correct use of the substance allows you to saturate the skin with oxygen and increases blood flow to problem areas, thereby improving the therapeutic effect on the skin.
Baziron AS product
Baziron®️ AS is an antibacterial, anti-inflammatory drug for external use. Effective in destroying bacteria that provoke the development of acne and acne Propionibacterium acnes, Staphylococcus epidermidis. By reducing skin oiliness, it prevents the occurrence of comedones.
Gel Baziron®️ AC for acne gives you self-confidence and a feeling of harmony with the world around you.
Composition of Baziron®️ AC gel
Baziron®️ AC gel contains benzoyl peroxide, an active substance that was specially developed to combat bacteria, an important cause of acne. Baziron®️ AS has been proven to kill 94% of acne-causing bacteria within just 1 week of use, for which the gel can be called an “ambulance” for acne.
In addition to fighting bacteria, Baziron®️ AS also regulates the functioning of the sebaceous glands (helps get rid of oily sheen) and normalizes oxygen supply to the skin. And what is especially important is that Baziron®️ AS is not an antibiotic, so this gel retains its effect over time, the skin “does not get used to the drug” (resistance (resistance) of bacteria to the effects of the drug does not develop).
And although Baziron®️ AS, a medicinal gel for acne, is sold in pharmacies without a doctor’s prescription, clinicians around the world have thoroughly studied this drug, which is included in both Russian and European clinical recommendations for the treatment of patients with acne for dermatologists.
Why is Baziron AC effective against acne?
The medicinal gel is widely prescribed by specialists to eliminate defects in problem skin. This is due to the large amount of benzoyl peroxide included in the product.
Thanks to this component, the secretion of the sebaceous glands is affected, due to which the secretion of fat is reduced, and the skin begins to receive more oxygen.
Penetrating into the epidermis, the components have an anti-inflammatory effect and eliminate bacteria that contribute to the appearance of skin defects.
The use of Baziron As allows you to achieve the following tasks:
- Improves the supply of oxygen to the layers of the epidermis;
- The natural process of restoration of epidermal cells is launched;
- Helps narrow pores, thereby eliminating scars;
- The inflammatory process is reduced;
- Normalization of the functioning of the sebaceous glands;
- Skin moisturizing;
- Eliminate germs that cause acne;
- The spread of germs to healthy areas is blocked;
- Pore cleansing;
- Dries purulent formations;
- Elimination of dead epidermal cells;
- Promotes the resorption of comedones;
- Removes toxins from the epidermis.
Widely used to prevent the appearance of inflammatory processes, especially in adolescence.
Instructions for use
To use the product, it is recommended to consult with a specialist who will correctly determine the type of gel and prescribe the most effective method of treatment.
Here are some simple rules for using the gel:
- For those patients who use the product for the first time, it is recommended to start treatment with a gel containing 2.5% of the active substance;
- Before application, it is necessary to thoroughly clean the skin using special antibacterial detergents;
- Distribute the gel evenly over the problem area of the skin;
- Apply the product twice a day, morning and evening;
- The course of treatment is up to three months. The course depends on the severity of the disease and is prescribed by a dermatologist on an individual basis.
If necessary, the dosage of Baziron As can be increased, however, this method of treatment is carried out only after consultation with a dermatologist.
Use during pregnancy and lactation
It is not recommended to use the drug during pregnancy and breastfeeding. Active components tend to penetrate the placenta and have a negative effect on the health of the fetus.
Use of the drug during lactation is passed on to the baby through mother's milk.
In case of urgent need, it is permissible to prescribe the drug for pregnant women in the second and third trimester. Such treatment is carried out in the minimum permissible doses and under the supervision of the attending physician.
Use in childhood
The use of Baziron AS is prohibited for children under 12 years of age.
For other cases, an individual treatment method is prescribed depending on the complexity of the disease. In case of a small number of inflammatory formations on the skin, it is recommended to apply the product using a spot method once a day.
Baziron AS: instructions for use, composition
Pharmacological action of the drug Baziron AS:
- Antimicrobial effect - benzoyl peroxide has a pronounced bactericidal effect against all known strains of bacteria Propionibacterium acnes and Streptococcus epidermidis, which play a large role in the development of inflammation and the appearance of inflammatory elements - papules and pustules (i.e. acne).
- Keratolytic effect - the drug dissolves intercellular cement in the stratum corneum of the epidermis and, accordingly, facilitates the desquamation of cells of the stratum corneum. This helps to expand the mouths of the follicles and facilitates the release of fatty secretions (sebum) from them to the surface of the skin.
- Reduces oily skin - according to the instructions for use, the drug suppresses the function of the sebaceous glands, thereby reducing oily skin.
Reviews on Baziron AC indicate that skin oiliness actually decreases slightly, but why this happens is actually a debatable question. On the one hand, there is no clear evidence in the scientific literature that benzoyl peroxide directly affects the sebocytes of the sebaceous glands, suppressing the hypersecretion of sebum. However, on the other hand, among the auxiliary components of the drug there are substances that simply neutralize the fatty acids themselves on the surface of the skin. And most likely, the reduction in fat content may be associated with this. In addition, drugs with benzoyl peroxide are almost always prescribed only in combination with topical retinoids, which in turn tend to suppress hypersecretion of the sebaceous glands.
- Reduces the content of free fatty acids - this effect is again associated with the antimicrobial activity of the drug.
The fact is that normally the secretion of the sebaceous glands does not contain free fatty acids (it contains only triglycerides). But when the ducts of the sebaceous glands are colonized by the bacteria P.acnes, the enzymes of these bacteria begin to break down triglycerides into monoglycerides (free fatty acids). As a result, the amount of the latter increases to 20% of the total volume of lipids produced by the sebaceous glands. Free fatty acids are comedogenic, i.e. they promote the formation of fat plugs (comedones) in the follicles. In addition, they change the process of keratinization - not only in the epidermis on the surface of the skin, but also in the depths of the hair follicles. In addition, free fatty acids have so-called “chemotaxis,” which means that they cause the migration of neutrophils to the follicles. In turn, the migration of neutrophils already leads to the formation of papules and pustules (pimples).
Baziron: composition and release form
The main active ingredient is the component “benzoyl peroxide”. There are 3 forms of the drug: the gel can have a concentration of benzoyl peroxide of 2.5%, 5% or 10% (each form is available in 40 g tubes). Externally, the gel has a uniform white color and is easily applied in a thin layer.
Gel composition (in terms of 100 g):
Active substance – benzoyl peroxide (anhydrous) → in 2.5% Baziron AS – 2.5 g, → in 5.0% Baziron AS – 5.0 g, → in 10.0% Baziron AS – 10.0 g. |
Excipients: methacrylic acid copolymer 2.0 g, glycerol 4.0 g, poloxamer-182 – 0.2 g, carbomer-940 – 0.8 g, disodium edetate 0.1 g, sodium docusate 0.05 g, propylene glycol 4.0 g, colloidal silicon dioxide 0.021 g, sodium hydroxide - up to pH 5.1-5.5, purified water - up to 100 g. |
→ Baziron AS official instructions (PDF)
What concentration of gel to choose -
For Baziron AS, the instructions for use do not contain detailed information about what concentration of gel is preferable to use. However, clinical studies have shown that the drug is approximately equally effective at concentrations of 2.5, 5.0 and 10%. But at the same time, skin irritation (contact dermatitis) will be more pronounced, the higher the concentration you use. Therefore, you should not immediately start even with 5.0% concentration.
If you are going to use a drug with benzoyl peroxide, then we recommend starting with a 2.5% gel. This will allow the skin to get used to this component. But in case of repeated courses of therapy, you can safely use 5.0% gel. As for the gel with 10% benzoyl peroxide, in fact it is only present in the instructions and is not sold in pharmacies. This concentration will cause very severe contact dermatitis.
How to apply the drug and how long the course of treatment lasts -
The drug is intended for external use only.
According to the instructions for use, the gel should be applied to the affected areas of the skin 1 or 2 times a day (morning and evening) with light massaging movements. First you need to cleanse the skin with mild detergents and dry it well. The course of treatment is 3 months. The effect of using the drug is usually noticeable within 4 weeks from the start of use. However, in no case should you stop using the drug at this point. To get a lasting effect for a long period of time, you need to complete a full 3-month course of treatment. At the same time, if you managed to achieve the disappearance of acne much earlier than this period, then at some point you can start using the drug only once a day.
Important: but the instructions for Baziron AS are one thing, and international protocols for the treatment of acne (papulopustular acne) are completely different. The instructions are compiled in such a cunning way that a person who decides to self-medicate gets the impression that to treat acne, monotherapy with only one drug, Baziron AS, is sufficient. But this is not at all true, and below we will talk about international acne treatment protocols, which are also used in Russia.
Side effects
In most cases, the human body tolerates the effects of the drug on the skin well and causes virtually no side effects.
However, individual cases may arise in which:
- Redness of the skin at the site of application of the gel;
- Peeling;
- Itching and burning;
- Allergic rashes in the form of small red pimples;
- Increased dryness of the skin;
- Headache;
- Nausea.
The substance should not be allowed to come into contact with mucous membranes; if contact occurs, it is recommended to rinse the organs with plenty of running water.
If any side effects occur, you should stop using and consult your doctor.
Side effect of the drug -
When using the drug, local skin irritation is possible, which is normal. Frequent symptoms of irritation include flaking and dry skin, redness, and a burning sensation. More rare symptoms include skin soreness and contact dermatitis. Rarely, allergic contact dermatitis may occur, which will require discontinuation of the drug.
In order to prevent or reduce the symptoms of irritation, we recommend that you start using Baziron AS with a 2.5% concentration of benzoyl peroxide. If symptoms of irritation do occur, then within 1-2 weeks you can switch to a single use of the drug (once a day), then returning to use 2 times a day (of course, if this was initially necessary).
Important : Benzoyl peroxide increases skin sensitivity to the sun. This means that when using the drug during periods of high solar activity, hyperpigmentation of the skin in the areas where the drug is applied is highly likely. Therefore, you will need to use sun protection products - no less than SPF 50; face-shading glasses, a Panama hat or a cap will also be useful. Let us remind you that products with SPF must be non-comedogenic (not clog pores), otherwise we will get an exacerbation of acne.
A good product SPF 50 for acne (in the form of a suspension) –
Contraindications for use –
- allergy to one of the components of the drug,
- children's age up to 12 years.
Special instructions - the drug can only be applied to the skin (not to the mucous membrane and red border of the lips). In case of contact with the mucous membranes of the nose, eyes, or mouth, rinse immediately with water. In addition, it is undesirable to use Baziron AC in parallel with products that have a drying, exfoliating effect, or alcohol-based products, because this will increase the irritant effect of the drug.
Use during pregnancy and lactation –
The drug has extremely low absorption from the surface of the skin, due to which it practically does not enter the bloodstream and does not have a systemic effect on the body. However, a large amount of breakdown products of benzoyl peroxide, namely benzoic acid, enters the body. No safety studies have been conducted during pregnancy and lactation. We hope that our article on the topic: Baziron AS price reviews was useful to you!
Sources:
1. Textbook on dermatology “Fitzpatrick's Dermatology” (8th edition), 2. “Etiology, pathogenesis, classification and clinical picture of acne vulgaris” (Barinova A.N.), 3. “Acne from the position of evidence-based medicine” (Anisimova M. .Yu.), 4. “Modern methods of treatment and rehabilitation of patients with acne vulgaris” (Barinova A.N.).
special instructions
Before using the drug, you must familiarize yourself in detail with the special conditions for using Baziron AS:
- If allergic reactions occur during treatment, it is recommended to stop the use of the drug, since the presence of inflammatory formations may increase;
- If there is damage to the skin, it is prohibited to use Baziron AS;
- It is forbidden to sunbathe during treatment with the drug , this may cause burns;
- It is not recommended to apply the gel in combination with other medications that dry out the epidermis;
- Additional medications to enhance treatment results are prescribed only by a specialist;
- For small areas affected by acne, Baziron AS is recommended to be applied using a spot method;
- In the first days of treatment, increased appearance of acne may be observed ; this is considered a normal course of treatment;
- After the results appear, you should not stop treatment ; you must complete the course completely. This is necessary to prevent the recurrence of acne.;
- Additional and repeated courses of treatment are carried out only after the appointment of a dermatologist;
- It is forbidden to apply a thick layer of Baziron AS , as skin disease dermatitis may occur;
- To eliminate flaking, it is recommended to additionally use Panthenol, which will not only moisturize the skin, but also relieve redness.
Following these simple steps allows you to quickly achieve the desired result and reduce the risk of re-formation of inflammatory areas.
Analogs
Cheap analogues of Baziron AS:
- Tetracycline ointment is widely used to eliminate purulent formations and acne. Recommended for preventive measures against the occurrence of inflammatory formations. The average cost of the ointment is 50 rubles ;
- Erythromycin - contains an antibiotic that effectively fights formations on problem skin. Recommended for eliminating large accumulations of pimples, as well as acne. Not used for a long time. Average cost 100 rubles;
- Metrogyl - used in the form of a gel to combat problem skin. This is a synthetic medicine that has a wide spectrum of antiprotozoal and antimicrobial effects. Average cost 160 rubles;
- Urodem - the drug is available in the form of a gel. Dermatologists prescribe it for minor inflammations. It contains a small percentage of benzoyl peroxide, as well as drugs of hormonal origin. That is why, before starting treatment, it is recommended to consult an experienced cosmetologist or dermatologist. The average cost of the product is 120 rubles;
- Baneocin (ointment) is an alternative solution. The composition of the medicine is not suitable for every person. The presence of fragrances and numerous additives can cause skin allergies. The average cost of the product is 190 rubles;
- Ugresol is a product available in the form of a lotion and is widely used to treat pimples and acne. The liquid structure of the product is used to eliminate excess sebum and reduce the redness of inflammatory formations. The average cost of the product is 120 rubles .
Tetracycline ointment
Erythromycin ointment
Metrogyl gel
Ugly
Baneocin Ugresol
More expensive similar drugs:
- Adaklin is a product designed specifically for the care of problem skin. The active components penetrate the layers of the epidermis and eliminate bacteria; it is widely prescribed to eliminate pimples and acne, and also reduces the appearance of scars after treatment. Average cost 450 rubles;
- Differin is a non-addictive drug and is therefore suitable for long-term treatment. The action of the substance is aimed at eliminating the cause of acne and reduces the likelihood of further spread of microbes to healthy areas of the skin. The cost of the drug is 700 rubles;
- Skinoren is the active ingredient of the drug azelaic acid, which effectively fights inflammatory formations and normalizes sebum production, which helps cleanse pores. The average cost of the drug is 600 rubles;
- Zenerit is the active ingredient erythromycin, the action of which is aimed at reducing the development of inflammatory formations and eliminating painful symptoms and purulent formations. It is recommended to use only after a doctor’s prescription and for a short course. Average cost 700 rubles;
- Curiosin is available in gel form. It is prescribed for minor skin lesions on the face. An alcohol solution cleans contaminated surfaces well. With constant application, the skin acquires a uniform structure and redness is significantly reduced. Average price 550 rubles;
- Benzac AS is a similar drug that contains the active component benzoyl peroxide. Effectively deals with acne and prevents its re-formation. Average price 500 rubles .
Adaklin
Differin
Skinoren
Zenerite
Curiosin
Benzac AS
Similar substances are recommended to be used only after studying the instructions, since each type of drug has its own side effects and can be perceived differently by the human body.
Which drug should I choose?
There is a wide selection of different drugs on the medicine market to combat problem skin. Therefore, the patient is faced with the question of which drug to choose? Let's compare some of them.
Which is better Baziron AC or Differin?
Both drugs are well tolerated by the skin and are not addictive, so they are used for long-term treatment. Medicinal substances have different active components, therefore they have different effects on the cause of acne formation.
The combined use of these substances is not permitted.
Experts differ in their opinions regarding which remedy is more effective. Both drugs are aimed at solving similar problems and require an individual prescription from a doctor.
The preference when choosing a drug is given depending on the type of problem. For example, Baziron AS effectively eliminates acne and pimples, and Differin, in turn, reduces the number of vulgar acne and helps eliminate age spots.
Therefore, the choice of drug for the treatment of problem skin depends on the patient’s personal preferences.
Which is better Baziron AS or Zinerit?
When comparing two medicinal substances, such as Zinerit and Baziron As, it should immediately be clarified that these two substances are aimed at different effects on the epidermis.
Zenerite fights surface problems and eliminates bacteria that are located inside the pores. Baziron AS, in turn, effectively eliminates the causes of inflammatory formations inside the skin layers and on the surface.
Application Zinerit has the property of being addictive, which makes it unsuitable for long-term use. Therefore, many dermatologists advise using Baziron As to eliminate skin defects.
What is better Baziron AS or Skinoren?
The use of these two drugs depends on the individual characteristics of the skin, therefore, before choosing a product, it is recommended to undergo appropriate diagnostics, based on the results of which the doctor will prescribe the most effective remedy.
Experts advise that if the use of Baziron AC does not bring the necessary results, then you need to use Skinoren.
If you have a large area of skin that has been affected by acne, it is more effective to use Skinoren, since it can be applied to the entire area of the epidermis in large quantities; Baziron AS is recommended to be applied only to places of inflammatory formations.
One of the advantages of Baziron AS is the ability to choose the most appropriate dosage of the product and its ability to moisturize the skin, while Skinoren dries the skin and can cause peeling. Also, very often, with sensitive skin, dryness and burning may occur at the application sites.
Baziron®️AS for teenagers
Juvenile acne is the “work” of millions of propionic acid bacteria (Propionibacterium acnes, modern name - Cutibacterium acnes), multiplying in the mouths of hair follicles. They feed on the secretion of the sebaceous glands, which are distributed to a greater or lesser extent throughout the skin.
In adolescence, during the period of hormonal shifts, excess secretion of sebum occurs, and bacteria actively multiply. Inflammation begins, which is aggravated by blockage of the sebaceous gland ducts with a large number of keratinized epithelial cells. In such cases, a drug such as Baziron®️ AS can come to the rescue, which, by acting on bacteria, fights the key cause of the disease and thereby helps reduce the visible signs of acne on the skin in the form of various rashes.
Release form and dosage Baziron® AS
In our country, Baziron® AS gel is available in two dosages: Baziron® AS 2.5% and Baziron® AS 5%. The therapeutic effect of both gels is comparable, but the 2.5% dosage is more “gentle” on the skin and “works” more delicately. If the patient has no previous experience of using the drug Baziron® AS, it is recommended to start treatment with this dosage.
In general, Baziron® AC 2.5% is recommended for sensitive skin prone to irritation. Baziron® AC 5% is optimal for people with oily, problem skin.
If your skin type is in doubt, then it is better to use Baziron® AC gel 2.5% during the first four weeks. After four weeks, if signs of acne remain and the skin responds well to treatment, then you can switch to a gel with a higher concentration - 5%.
Reviews
Reviews about the drug Baziron AS: