Unlike the similar three-component Triderm, which is produced by the same company, Belgian Celestoderm contains only one or two ingredients in both forms. In the latter, an antibacterial component is additionally included in the composition, and “with garamycin” is added to the name. Let's take a closer look at the difference between these versions and in which cases it would be better to use cream or ointment.
Indications for use
Inflammatory skin diseases sensitive to glucocorticosteroid therapy:
- contact and seborrheic dermatitis ;
- radiation dermatitis;
- eczema;
- solar dermatitis;
- neurodermatitis;
- exfoliative dermatitis;
- psoriasis;
- intertriginous dermatitis;
- anogenital itching.
Instructions for use Celestoderm-B (Method and dosage)
Celestoderm ointment, instructions for use
The ointment is used externally only. It should be applied to the affected areas in a thin layer up to three times a day, depending on the severity of the disease. To achieve the effect, in most cases, applying the ointment twice a day is sufficient.
Celestoderm cream, instructions for use
The cream is used externally only. It should be applied to the affected areas in a thin layer up to three times a day, depending on the severity of the disease. To achieve the effect, in most cases, applying the cream twice a day is sufficient.
What is the difference?
betamethasone as the main active substance.
, relieving inflammation, redness and itching. Don’t let its hormonal effect scare you; if you use it in the recommended quantity and frequency (1-2 times a day), and do not smear it on open wounds and large surfaces of the skin, then betamethasone will only work at the site of application, without having a negative effect on the body. Effective for almost all types of non-infectious dermatitis, psoriasis and itching.
If the lesion is complicated by a bacterial infection, which often occurs when scratching, contact with dirty surfaces, or untimely treatment with antiseptics, then it is better to use the next option.
The composition of Celestoderm with garamicin, in addition to the same GCS, includes the antibiotic gentamicin
. This is a powerful antimicrobial agent that, when applied externally, destroys most pathogens. Like betamethasone, gentamicin, when used correctly, practically does not penetrate into the blood and does not cause side effects characteristic of general antibiotics. The combination will work well for most infectious dermatitis, except viral or fungal ones.
Celestoderma does not have an antifungal agent, so it will not be effective for mycotic lesions. In this case, it is better to use the above-mentioned Triderm, which contains clotrimazole (for fungi) or its Russian analogue Akriderm GK as a third link.
Overdose
Signs of overdose: excessive or prolonged local use of glucocorticosteroids can cause suppression of the pituitary and adrenal glands, which can cause the development of secondary hypofunction of the adrenal cortex and symptoms of hypercortisolism, including Cushing's syndrome .
Overdose therapy: symptomatic treatment. If necessary, monitoring and correction of electrolyte imbalance is recommended. Acute hypercortisolism is usually reversible. In case of prolonged exposure, slow withdrawal of corticosteroids .
Overdose of the drug Celestoderm-v, symptoms and treatment
Excessive or long-term use of topical corticosteroids, especially in children, can lead to suppression of the hypothalamic-pituitary-adrenal axis with the development of secondary adrenal insufficiency and symptoms of hypercortisolism, including Cushing's syndrome. Long-term topical use of gentamicin can lead to the growth of resistant fungal or bacterial microflora. Treatment is symptomatic. Symptoms of acute hypercortisolism are usually reversible. If necessary, electrolyte balance is corrected. In case of chronic toxic effects, gradual withdrawal of GCS is recommended. In case of excessive growth of resistant microorganisms, the necessary therapy for infectious complications is prescribed; Adequate antifungal and antibacterial therapy should be carried out.
special instructions
If there is no effect of treatment within 14 days, then you need to consult a doctor to clarify the diagnosis.
If irritation or an allergic reaction is detected when using the drug, then treatment should be stopped and adequate therapy should be selected for the patient.
If a secondary bacterial or fungal infection develops, it is recommended to prescribe appropriate medications. If a rapid therapeutic effect cannot be achieved, then the use of glucocorticosteroids should be discontinued until all signs of infection are eliminated.
Any adverse reactions of systemic glucocorticosteroids , including adrenal suppression, can also be recorded when using local glucocorticosteroids , especially in children.
The absorption of local glucocorticosteroids into the systemic circulation is increased with their prolonged use, when treating large surfaces of the body or when using occlusive dressings, as well as when treating children.
Celestoderm-B cream and ointment are approved only for external use and are prohibited for use in ophthalmology.
The following adverse reactions were recorded in children receiving this drug: Cushing's syndrome , suppression of the hypothalamic-pituitary-adrenal system, growth retardation, increased intracranial pressure, and delayed weight gain. Signs of suppression of the adrenal cortex in children include: decreased cortisol in the blood, lack of response to activation by adrenocorticotropic hormone . Increased intracranial pressure can be detected by bulging of the fontanel, swelling of the optic disc and is accompanied by headache.
Dermatitis: which cream to choose?
This problem causes discomfort and, in some cases, fear and confusion. Symptoms of dermatitis can affect not only your health, but also your work and personal life. It causes particular concern among young parents, like any illness in the baby.
Dermatitis is usually called any kind of manifestation on the skin that differs from its normal state: redness, peeling, itching, and so on.
If any changes occur, consult a specialist. It is worth noting that 10% of all visits to a dermatologist are related to manifestations of dermatitis. Women apply more often due to greater contact with household chemicals.
Types of Dermatitis
There are two main groups of dermatitis: contact and allergic.
The manifestations of contact dermatitis are:
Acute - the onset is rapid after a single interaction with substances that have a pronounced irritant effect.
Chronic - develops gradually with constant contact with an irritant over several days or even years. In this case, the cause will be mild irritants such as: household chemicals, soap solutions, dry air, dust.
Allergic dermatitis is a manifestation of a malfunction of the body's immune system to one or more irritants, manifested by inflammation.
The most common places of manifestations:
- Skin of hands
- Face
- Neck
- Armpits
- Scalp
- Anogenital area, most often in children.
- Ears
- Shin
- Feet
The manifestations of acute contact and allergic dermatitis are very similar: redness, swelling and rashes in the form of bubbles and blisters and “pimples”. Itching, burning, and soreness of the skin will also be felt. With allergic dermatitis, the manifestations will not be limited to the place of skin contact with the irritant; the reaction goes far beyond its limits. As a result, mandatory consultation with a specialist is necessary to confirm the correct diagnosis and treatment.
In chronic dermatitis, the lesions do not look as bright as in acute dermatitis, but also have swelling, which can be accompanied by: cracks, hyperpigmentation and damage to the integrity of the skin, the desire to scratch and pinch it. Even after eliminating the impact of the irritant, the process can continue for up to several months.
To make an accurate diagnosis, the doctor will need to tell you in detail how, when and after what the skin lesion occurred. Skin tests will also be performed.
Dermatitis is usually called any kind of manifestation on the skin that differs from its normal state.
Treatment
The main goal of treatment is to return the person to the previous comfort and condition of the skin. The priority in the treatment of contact dermatitis is to identify the irritating factor and eliminate it. If it is impossible to eliminate contact, for example, due to professional necessity, adequate and reliable skin protection must be selected (overall clothing, gloves, protective creams and ointments). For simple contact dermatitis, the effectiveness of hormonal ointments and creams is not enough. The effectiveness of the use of selective alcineurin inhibitors tacrolimus and pimecrolimus for the types of dermatitis indicated in the article has not been proven in controlled studies.
In case of severe itching, it is possible to use antihistamines - Zodak, Claritin, Xestin, Erius, Suprastinex, Dizal, Alegra, Xyzal, Fenistil.
Local treatment:
- Cutivate (fluticasone propionate) cream, ointment for 2 weeks
- Triacort, Fluorocort (triamcinolone acetonide) ointment 0.025%, 0.1% for 2 weeks, treatment must begin with a higher dose
- Dermovate, Clobetasol, Psoriderm, Dilasen, Powercourt (clobetasol propionate) ointment for 3–4 weeks
- Akriderm, Beloderm, Celestoderm (betamethasone valerate) cream, ointment 2 weeks
- Uniderm, Elokom, (mometasone furoate) cream, ointment 0.1% 2 weeks
It happens that a bacterial infection can join the course of the underlying dermatitis. In this case, it is worth connecting additional local antibacterial therapy:
- Fucidin (fusidic acid) cream, gel 2% for 1–2 weeks
- Supirocin, Bactroban (mupirocin) ointment 2% for 2 weeks
If there is no result in the treatment of allergic dermatitis, it is possible to use immunosuppressive drugs cyclosporine, azathioprine. Application of UV-B or PUVA therapy.
Prevention of dermatitis is the understanding that this reaction is lifelong and even short-term contact should be avoided.
Reminder for hand skin care for occupational contact dermatitis:
- Be sure to wear gloves
- Use soap substitutes. Soap removes the protective fatty layer of the skin and damages the stratum corneum of the skin, which retains water, thereby greatly increasing permeability to any substances. In addition, some soap components themselves are irritating.
- Avoid Potentially Irritating Substances
- Follow your doctor's recommendations for at least six months
- Do not wear rings as they are a place where irritants accumulate, and if a person is still not ready to give up wearing them, then it is necessary to remove them while working and doing household chores.
- Also regularly use emollients - these are substances similar in composition to the natural protective fatty film of the skin, affecting the upper layers of the skin. They are: natural, chemical, synthetic.
Available daily care products that can be purchased at any pharmacy: Bepanten, Tipikrem, Emolium, Mustela, Lipobase, La-cree.
For adults only: Lokoid, Dermovate, Sinalar. They should only be applied to clean, dry skin.
One of the new directions is the use of corneoprotectors. These are products that restore the integrity of the stratum corneum directly. Physiogel, Oilatum, Lipikar, Protopic.
By self-medicating, you can cause irreparable harm to your health; be sure to consult a doctor and follow his recommendations.
Literature: Federal clinical guidelines for the management of patients with contact dermatitis, Moscow - 2015
Analogs
Level 4 ATC code matches:
Gistan-N
Sinalar
Avecourt
Mesoderm
Momederm
Betazon
Silkaren
Elokom
Flucinar
Sinaflan
Cutivate
Advantan
Betamethasone
Beloderm
Mometasone Furoate
Uniderm
Momat
Analogues of Celestoderm-B: Akriderm , Beloderm , Betliben , Soderm , Advantan , Sterocort , Metizolone , Cutivate .
During pregnancy and lactation
The safety of using the drug in pregnant women has not been established, so its use during pregnancy can only be justified if there are strict indications and under the supervision of the attending physician. The described remedy should not be prescribed to pregnant women in large dosages or for a long time.
It has not yet been clarified whether local glucocorticosteroids be excreted in breast milk, so breastfeeding or taking the drug should be stopped, taking into account the need for its use for the mother.
Celestoderm-B price, where to buy
The price of Celestoderm-B ointment 30 g in Russia averages 300 rubles; in Ukraine, this form of release costs 190-210 hryvnia.
The price of Celestoderm-B cream 30 g in Russia is 300-325 rubles, in Ukraine this form of release costs 180-225 hryvnia.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Celestoderm in cream 0.1% 15gSchering-Plough Labo NV
RUB 228 order - Celestoderm in cream 0.1% 30gSchering-Plough Labo NV
RUB 292 order
- Celestoderm-B with garamycin cream d/nar. approx. tube 15g No. 1Schering-Plough Labo NV
470 rub. order
- Celestoderm B ointment 0.1% 30gSchering-Plough Labo NV
RUB 306 order
- Celestoderm B with garamycin ointment 15gSchering-Plough Labo NV
465 rub. order
Pharmacy Dialogue
- Celestoderm-B cream tube 0.1% 15gShering-Plough
RUB 237 order
- Celestoderm-B ointment (tube 0.1% 30g) Bayer/Shering-Plough
RUB 311 order
- Celestoderm-B ointment tube 0.1% 15gShering-Plough
RUB 207 order
- Celestoderm-B ointment tube 0.1% 30gShering-Plough
RUB 294 order
- Celestoderm-B with garamycin ointment tube 0.1% 15gShering-Plough
RUR 444 order
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Pharmacy24
- Celestoderm B with garamycin 30 g cream Schering-Plough Labo N.V., Belgium
138 UAH order
PaniPharmacy
- Celestoderm B ointment Celestoderm-B ointment 0.1% 15g Belgium, Schering-Plough Labo
136 UAH order
- Celestoderm B ointment Celestoderm-B ointment 0.1% 30g Belgium, Schering-Plough Labo
199 UAH order
- Celestoderm with garamycin ointment Celestoderm-B with garamycin ointment 30g Belgium, Schering-Plough Labo
154 UAH order
- Celestoderm with garamycin cream Celestoderm-B with garamycin cream 30g Belgium, Schering-Plough Labo
151 UAH order
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What is better to choose - cream or ointment?
The composition and richness of the texture that distinguishes Celestoderm cream from ointment depends on the appropriateness of choosing the form. A more watery cream base affects:
- Possibility of use for weeping lesions. This does not mean a bleeding open wound, but an exudative process (effusion) on the surface. Water and alcohol in the composition will provide a drying effect.
- Good ability to absorb and evaporate. It is quickly absorbed and will have a “cooling” effect.
- Speed of action. In most cases, the cream is more likely to relieve itching and redness.
In turn, Celestoderm ointment will be better for:
- Apply to dry and keratinized areas (without bleeding cracks). A thicker base will soften the damage well and stay longer in the coarsened layer.
- Increased skin sensitivity. The ointment contains much less preservatives and formative substances than the cream - only paraffin and no alcohol.
- Using dressings and plasters. In general, local GCS-containing products are not recommended for use under dressings, especially occlusive (sealed), due to the risk of systemic action. If such a need nevertheless arises, then the ointment will be better due to its slower absorption.
Both forms are available in tubes of 15 or 30 g; the same volume of cream will cost 10-15% less.
