“Posterizan” is an effective suppository that allows you to cure hemorrhoids in just a few days. The drug can be used even during pregnancy and lactation. There are practically no contraindications or side effects. Therefore, the product is recommended by more than 90% of buyers.
Composition and release form
| Ointment | 1 g |
| microbial cells of E. coli killed by phenol | 500 million |
| hydrocortisone (in 166.7 mg aqueous suspension) | 2.5 mg |
| excipients: lanolin; Vaseline (yellow) or paraffin (yellow, soft); phenol |
in aluminum tubes (with applicator) 25 g, complete with applicator; 1 tube in a box.
| Rectal suppositories | 1 sup. |
| microbial cells of E. coli killed by phenol | 1000 million |
| hydrocortisone (in 387.1 mg aqueous suspension) | 5 mg |
| excipients: solid fat; macrogolglycerol; hydroxystearate; acetylcysteine; phenol (preservative); ethylenediaminetetraacetate disodium salt |
5 pcs in blister; There are 2 blisters in a box.
Posterisan Forte ointment for external and rectal use 25g
Compound
Active ingredients: inactivated microbial cells E. coli - 500 million, hydrocortisone - 2.5 mg. Excipients: lanolin, petroleum jelly, phenol (preservative).
Pharmacokinetics
Data on the pharmacokinetics of the drug are not provided.
Indications for use
The ointment is prescribed to adults for the following diseases:
- persistent hemorrhoids;
- perianal dermatitis;
- anal itching, especially resistant to other medications;
- anopapillitis;
- anal fissure.
Contraindications
- bacterial infections in the treatment area (for example, tuberculosis, syphilis, gonorrhea);
- fungal infections in the area of treatment;
- hypersensitivity to hydrocortisone or other components of the drug.
Directions for use and doses
The ointment is applied in a thin layer to the affected area of the skin and mucous membrane in the morning and evening, as well as after each act of defecation. For deeper introduction of the ointment into the anal canal, you can use the screw-on applicator included with the kit.
Storage conditions
The drug should be stored in a dry place, protected from light and out of reach of children, at a temperature of 0° to 25°C.
Best before date
3 years. Do not use after the expiration date stated on the package.
special instructions
Phenol is used as a preservative in the preparation.
Description
A drug for topical use for diseases of the anorectal area.
Dosage form
Ointment for rectal and external use is yellowish to light brown in color, homogeneous, with a characteristic odor of phenol.
Action
A drug with anti-inflammatory and immunostimulating effects for topical use.
Cell wall antigens and metabolic products of Escherichia coli upon contact with the rectal mucosa and skin of the anogenital area increase local tissue resistance to the effects of pathogenic microflora. The drug stimulates the T-system of immunity, the phagocytic activity of leukocytes and cells of the reticuloendothelial system, nonspecific immune factors, reduces exudation during inflammation, normalizes the permeability and tone of blood vessels, and stimulates the regeneration of damaged tissues.
Hydrocortisone, when applied topically, has anti-inflammatory and antiallergic effects. When applied to the affected surface, it reduces swelling, hyperemia, and itching.
Side effects
Possible: allergic reactions in patients with hypersensitivity to phenol.
Use during pregnancy and breastfeeding
There is no evidence that when using the drug Posterisan® forte, hydrocortisone crosses the placental barrier or is excreted in breast milk. To date, no information has been found indicating a damaging effect of the drug on the fetus.
At the same time, Posterizan® forte, like all medications, should be used during pregnancy and lactation only as prescribed by a doctor.
Interaction
When used simultaneously with other drugs containing corticosteroids (tablets, drops or injection solutions), the effects or side effects may mutually increase.
Overdose
Currently, no cases of overdose of Posterisan® Forte have been reported.
Pharmacodynamics
A combined drug containing two active components - a suspension of a bacterial culture containing inactivated bacteria and their metabolic products, and hydrocortisone. Stimulates the T-system of immunity, increases the phagocytic activity of leukocytes and cells of the reticuloendothelial system, increases the role of a number of humoral factors of nonspecific immunity (induces the formation of cytokines), enhances the formation of antibodies at the site of exposure. Concentrated lipopolysaccharides of cell membranes and metabolites of E. coli of various strains, incl. resistant to antibiotics and other antibacterial agents, lead to an increase in local tissue resistance to the effects of pathogenic microflora. Hydrocortisone (contained in a small dose) complements the effect of a bacterial culture suspension due to its anti-inflammatory, antiallergic and antipruritic effect, which is manifested in reducing exudation, normalizing the permeability and tone of blood vessels, reducing swelling, hyperemia, itching, and stimulating the regeneration of damaged tissues.
pharmachologic effect
A drug for topical use for diseases of the anorectal area.
The cell wall antigens and E. coli metabolites contained in Posterisan, upon contact with the mucous membrane of the rectum and the skin of the anogenital area, increase the local resistance of tissues to the effects of pathogenic microflora.
The drug stimulates the T-system of immunity, at the site of exposure increases the phagocytic activity of leukocytes and cells of the reticuloendothelial system, nonspecific immune factors, reduces vascular exudation during inflammation, normalizes the permeability and tone of blood vessels, stimulates the regeneration of damaged tissues.
Directions for use and doses
Externally, rectally. Apply a thin layer to the affected area in the morning and evening, as well as after each bowel movement. For deeper introduction of the ointment into the anal canal, you can use a screw-on applicator. Rectal suppositories are used in the acute period of the disease, 2–3 pcs. per day. After eliminating the subjective symptoms of the disease, the affected area continues to be lubricated once a day or 1 supp. 1 time per day for several days. If the drug is used to treat chronic dermatitis, then after the disappearance of skin manifestations, it is recommended to extend therapy for another 1–2 weeks. The combined use of ointments and suppositories is possible. After completing the course of treatment, to consolidate the therapeutic effect, it is advisable to use a drug (ointment or suppositories) that does not contain hydrocortisone for another 2-3 weeks.
Dosage regimen
The ointment should be applied in a thin layer to the affected area of the skin and mucous membrane in the morning and evening, as well as after each act of bowel movement. To insert the ointment deeper into the anus, you can use the screw-on applicator included with the kit.
Suppositories are used 1 in the morning and in the evening, as well as after each act of defecation.
The combined use of ointments and suppositories is possible.
The duration of treatment is 2-3 weeks.
What is the difference between Posterisan and Posterisan Forte?
These are two analogues that contain the same active ingredient - E coli bacteria. However, the amount of this component differs (per 1 g):
- “Posterizan” – 300 million units;
- “Posterizan Forte” – 500 million units.
The “Forte” variety also contains hydrocortisone in the amount of 2.5 mg per 1 g. The auxiliary components are:
- petrolatum;
- lanolin;
- phenol.
In terms of indications, contraindications, and side effects, the drugs are no different. They also have similar instructions for use. It is worth keeping in mind that Forte is used in advanced cases, when hemorrhoids, itching, anal fissures and other symptoms have been observed for a long time and in an obvious form.
As for the usual form “Posterizan”, it is used at the initial stage. If it is difficult to decide on a course of therapy on your own, it is recommended to first consult a doctor. Any self-medication carries certain risks.
Contraindications and side effects
The product can be used by almost all patients, with the exception of cases of individual intolerance to phenol, which is also included in the suppositories. During pregnancy and during breastfeeding, treatment with suppositories and ointments is possible, but only in consultation with a doctor.
Sometimes side effects associated with an allergic reaction to phenol are observed. The skin may itch and become red. In such cases, it is necessary to stop taking it and consult a doctor for a possible change in therapy.
Candles “Posterizan”: description, composition
The drug "Posterizan" is available in the form of ointments and suppositories (rectal suppositories), which are used to treat hemorrhoids. The composition includes inactive microbial cells of the E coli strain - 330 million units per 1 g. Auxiliary components are lanolin, phenol, paraffin and petroleum jelly.
Candles have a complex effect:
- counteraction to inflammatory processes;
- antipruritic effect;
- tissue restoration;
- development of both types of immunity – specific and nonspecific.
The inactivated bacteria included in the suppositories affect the T cells of the immune system. E. coli interact with the cells of the rectum and the skin of the rectal area. They increase tissue resistance to pathogenic bacteria, making recovery faster and more effective.
Also, the use of the drug in the form of ointments and suppositories increases vascular tone and reduces their esudation (the release of blood from small vessels). In addition, the active components help restore vascular permeability, which is also important for healing.
Instructions for use "Posterizan"
Suppositories are used rectally 2 times a day - in the morning immediately after sleep, and also in the late evening just before bedtime. Moreover, if there is a need, you first need to go to the toilet and only then light a candle, having previously completed a hygienic procedure.
The ointment is also applied 2 times a day to the rectal area. The principle of use is exactly the same - you first need to rinse the anal passage and wipe dry. If necessary, first go to the toilet and only then rub in the composition with gentle massage movements.
The course of treatment, regardless of the form of the drug, lasts 7 days in a row. Then a break is taken, after which, if necessary, the course can be repeated, but only in agreement with the doctor. Effective therapy often requires a change in drug.
If the described rules are followed, Posterizan ointment and suppositories are safe for health. No cases of overdose have been reported. But if an allergic reaction is observed, treatment is stopped and a specialist is consulted for additional consultation.
Posterisan forte
Instructions for medical use of the drug
Posterisan® forte
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Registration certificate No. P N014065/01 dated 05/14/2010, P N014065/02 dated 01/12/2010
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Dosage form:
– ointment for rectal and external use,
– rectal suppositories.
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Composition and release form
The active components of the drug are corpuscular components and metabolic products of Escherichia coli and hydrocortisone.
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Ointment: 1 g of ointment contains phenol-inactivated microbial cells of E. coli (500 million), hydrocortisone 2.5 mg.
Excipients: lanolin, petroleum jelly, phenol (preservative).
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Suppositories: 1 suppository contains phenol-inactivated microbial cells of E. coli (1000 million), hydrocortisone 5 mg.
Excipients: acetylcysteine, α-tocopherol, disodium edetate, macrogol-glycerol, hydroxystearate, solid fat, phenol (preservative).
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Description
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The ointment is homogeneous from yellowish to light brown in color with a characteristic smell of phenol.
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Suppositories are torpedo-shaped suppositories from white to yellowish in color with a characteristic smell of phenol.
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Pharmacotherapeutic group
Antihemorrhoidal drugs for topical use, combination.
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CODE ATH C05AX03
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Biological properties
Cell wall antigens and metabolic products of Escherichia coli upon contact with the rectal mucosa and skin of the anogenital area increase local tissue resistance to the effects of pathogenic microflora. The drug stimulates the T-system of immunity, the phagocytic activity of leukocytes and cells of the reticuloendothelial system, nonspecific immune factors, reduces exudation during inflammation, normalizes the permeability and tone of blood vessels, and stimulates the regeneration of damaged tissues.
Hydrocortisone, when applied topically, has anti-inflammatory and antiallergic effects. When applied to the affected surface, it reduces swelling, hyperemia, and itching.
,
Indications for use
,
The ointment is prescribed to adults for the following diseases:
– persistent hemorrhoids,
– perianal dermatitis,
– anal itching, especially resistant to other medications,
– anopapillitis,
- anal fissure.
,
Suppositories are prescribed to adults for the following diseases:
– persistent hemorrhoids,
– anal itching, especially resistant to other medications,
– anopapillitis,
- anal fissure.
Directions for use and dosage
,
The ointment is applied in a thin layer to the affected area of the skin and mucous membrane in the morning and evening, as well as after each bowel movement. For deeper introduction of the ointment into the anal canal, you can use the screw-on applicator included with the kit.
,
Rectal suppositories are used in the morning and evening, as well as after each bowel movement. The combined use of ointments and suppositories is possible.
The course of treatment lasts 2–3 weeks.
,
Side effect
Phenol is used as a preservative in the drug, so allergic reactions are possible in patients with hypersensitivity to this component.
,
Contraindications
Hypersensitivity to hydrocortisone or other components of the drug.
Bacterial diseases in the area of treatment (for example, tuberculosis, syphilis, gonorrhea).
Fungal diseases in the treatment area.
,
Use during pregnancy and lactation
There is no indication that hydrocortisone from Posterizan® forte ointment or suppository enters the placenta or breast milk. To date, no information has been found indicating a damaging effect of the drug on the fetus.
At the same time, Posterisan® forte ointment or suppositories, like all medications, should
Use during pregnancy and lactation only under strict medical supervision.
,
Interaction with other drugs
With the simultaneous use of Posterisan® forte ointments or suppositories and other drugs with glucocorticoids (tablets, drops or injections), the effects or side effects may be increased.
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Please note that these instructions may also apply to recently used medicines.
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Release form
Ointment 25 g in an aluminum tube, in a cardboard pack.
Rectal suppositories, 5 pieces in a blister, 2 blisters (10 suppositories) in a cardboard pack.
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Storage conditions
In a dry place, protected from light and out of reach of children, at a temperature of 0 to 25 °C.
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Best before date
Ointment – 3 years.
Suppositories – 2 years.
Do not use after the expiration date indicated on the package!
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Conditions for dispensing from pharmacies
Over the counter.
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