Ciprofloxacin is a broad-spectrum antimicrobial drug that is prescribed to patients for various eye diseases and ENT infections. Prescribed for patients of the older age category. There are contraindications that should not be ignored to avoid adverse reactions. Before starting the course, it is recommended to take into account drug interactions.
The product is distinguished by its low cost - 40–120 rubles. The price depends on the packaging and release form. The selection of Ciprofloxacin analogs in injections, ear and eye drops, and tablets is carried out exclusively by the attending physician.
Compound
Ciprofloxacin ear and eye drops contain ciprofloxacin hydrochloride at a concentration of 3 mg/ml (in terms of pure substance), Trilon B, benzalkonium chloride, sodium chloride, purified water.
The active substance is also contained in the eye ointment at a concentration of 3 mg/ml.
Ciprofloxacin tablets: 250, 500 or 750 mg of ciprofloxacin, MCC, potato starch, corn starch, hypromellose, croscarmellose sodium, talc, magnesium stearate, colloidal anhydrous silicon dioxide, macrogol 6000, additive E171 (titanium dioxide), polysorbate 80.
The solution for infusion contains the active substance at a concentration of 2 mg/ml. Excipients: sodium chloride, disodium edetate, lactic acid, diluted hydrochloric acid , water for injection.
Ciprofloxacin or Ciprolet – which is better, what is the difference
Manufacturer: DR.
REDDIS, India Release form: tablets, eye drops, solution for infusion
Active ingredient: inidazole + ciprofloxacin
How to replace Ciprofloxacin tablets? Tsiprolet is an analogue that belongs to combination drugs. The drug has an antimicrobial effect. Has a detrimental effect on pathogenic microorganisms - bacteria. It is recommended to take according to the prescribed dosage.
There are significant contraindications, which are recommended to be familiarized with before starting a course of using ciprofloxacin solution or tablets in order to exclude adverse reactions from the body.
Pharmacodynamics and pharmacokinetics
Is ciprofloxacin an antibiotic or not?
The antibiotic Ciprofloxacin is an early fluoroquinolone (1st generation drug) and is used mainly for hospital infections . The drug penetrates well into cells and tissues (including bacterial cells and macroorganisms) and has good pharmacokinetic parameters.
Pharmacodynamics
The mechanism of action of the drug is due to the ability to inhibit DNA gyrase (an enzyme in bacterial cells) with disruption of DNA synthesis, division and growth of microorganisms.
Wikipedia states that the use of the drug does not develop resistance to other antibiotics . This makes Ciprofloxacin highly effective against bacteria resistant to penicillins , caminoglycosides , tetracyclines , cephalosporins and a number of other antibiotics .
Shows the greatest activity against Gram (-) and Gram (+) aerobes: H. influenzae, N. gonorrhoeae, Salmonella spp., P. aeruginosa, N. meningitidis, E. coli, Shigella spp.
Effective against infections caused by: strains of staphylococci (including those producing penicillinase), certain strains of enterococci , legionella , campylobacteria , chlamydia , mycoplasmas , mycobacteria .
Active against beta-lactamase-producing microflora.
Anaerobes are moderately sensitive or resistant to the drug. Therefore, in patients with mixed anaerobic and aerobic infection, treatment with ciprofloxacin should be supplemented with lincosamides or Metronidazole .
Resistant to the antibiotic are: Ureaplasma urealyticum, Streptococcus faecium, Treponema pallidum, Nocardia asteroides.
Resistance of microorganisms to the drug develops slowly.
Pharmacokinetics
After taking the tablet, the drug is quickly and completely absorbed into the gastrointestinal tract.
Main pharmacokinetic parameters:
- bioavailability - 70%;
- TCmax in blood plasma - 1–2 hours after administration;
- T½ - 4 hours
From 20 to 40% of the substance binds to plasma proteins. Ciprofloxacin is well distributed in biological fluids and tissues of the body, and its concentration in tissues and fluids can significantly exceed plasma concentrations.
It penetrates the cerebrospinal fluid through the placenta, is excreted into breast milk, and high concentrations are recorded in bile. Up to 40% of the dose taken is eliminated unchanged within 24 hours by the kidneys, part of the dose is excreted in the bile.
pharmachologic effect
Manufacturer: PHARMSTANDARD+, Russia
Release form: eye drops, tablets for oral administration
Active ingredient: ciprofloxacin
The drug is an antimicrobial agent that has a bactericidal effect. The active component is active against most gram-negative pathogenic microorganisms. Penetrates inside the cell and destroys it, preventing it from spreading throughout the body.
This drug is rapidly absorbed from the gastrointestinal tract. Food intake has a slight effect on the absorption of the drug. Evenly distributed throughout tissues and organs. It is excreted from the body along with urine and bile.
Ciprofloxacin 500 tablets - is it an antibiotic or not?
Ciprofloxacin is a drug that belongs to the class of antibiotics and fights a large number of bacteria that provoke various infectious diseases. Therefore, it is recommended to take probiotics during and after the course of this remedy. They will help restore intestinal microflora and normalize the functionality of the gastrointestinal tract.
Indications for use of Ciprofloxacin
Ciprofloxacin - what are these tablets/solution for?
Ciprofloxacin is prescribed for the treatment of infectious diseases of the ENT organs, pelvic organs, bones, skin, joints, abdominal cavity, respiratory tract, urogenital and postoperative infections caused by flora sensitive to the drug.
The drug can be used in patients with immunodeficiency conditions (including conditions that develop with neutropenia , or are caused by the use of immunosuppressants ).
Ciprofloxacin (like other early fluoroquinolones) is the drug of choice for the treatment of UTIs, including but not limited to hospital-acquired infections.
Due to their ability to penetrate well into tissues and, in particular, into prostate tissue, fluoroquinolones have practically no alternative in the treatment of bacterial prostatitis .
Showing high activity against the most likely pathogens of hospital pneumonia ( Staphylococcus aureus , Enterobacteriaceae and Pseudomonas aeruginosa ), it is important for pneumonia associated with the need for artificial ventilation.
If the causative agent of the disease is P. aeruginosa, its sensitivity to ciprofloxacin should be established before prescribing the drug. This is due to the fact that in intensive care units more than a third of Pseudomonas aeruginosa are resistant to the drug.
The drug is important for intra-abdominal surgical infections and infections of the hepatobiliary system . To prevent infection, it can be prescribed to patients with pancreatic necrosis .
Fluoroquinolones are not used for CNS infections. This is due to their low penetration (penetration) into the cerebrospinal fluid. At the same time, they are effective against meningitis , the causative agents of which are Gram (-) bacteria resistant to 3rd generation cephalosplorins.
The presence of several dosage forms allows the drug to be used for step-down therapy. When switching from IV administration of Ciprofloxacin to oral administration, the oral dose should be increased in order to maintain therapeutic concentrations.
So, if a patient was prescribed 100 mg intravenously, then he should take 250 mg orally, and if 200 mg was administered intravenously, then 500 mg.
What is the medicine for in the form of eye/ear drops?
In ophthalmology it is used for superficial bacterial infections of the eye (s) and its appendages, as well as for ulcerative keratitis .
Indications for the use of Ciprofloxacin in otology: acute bacterial otitis of the external ear and acute bacterial otitis of the middle ear in patients with a tympanostomy tube .
Ciprofloxacin or Azithromycin - which is better and stronger
Manufacturer: Vertex, Russia
Release form: capsules
Active ingredient: azithromycin
What else can replace Ciprofloxacin? Azithromycin is an antibiotic that has a broad spectrum of action. Has bacteriostatic and bactericidal effects.
An analogue of Ciprofloxacin 500 mg tablets is prescribed to patients over 12 years of age in the following conditions:
- Infectious diseases of the upper and lower respiratory tract, ENT organs.
- Microbial lesions of the skin and soft tissues.
- Infectious diseases of the genitourinary system.
- Borreliosis.
- As part of combination therapy for gastrointestinal diseases caused by Helicobacter pylori.
Before starting the course, it is recommended to take into account contraindications. The analogue can be used during pregnancy, but only after comparing the risks and benefits. Azithromycin is also used in dentistry to treat infectious diseases of the oral cavity.
Contraindications
Contraindications for systemic use:
- hypersensitivity;
- pregnancy;
- lactation;
- severe kidney/liver dysfunction ;
- indications of a history of quinolone-induced tendonitis.
Eye and ear drops are contraindicated for fungal and viral infections of the eyes/ears , intolerance to Ciprofloxacin (or other quinolones), and during pregnancy and lactation.
For children, tablets and solution for intravenous administration can be prescribed from 12 years of age, eye and ear drops - from 15 years of age.
Side effects
The drug is well tolerated. The most common side effects with intravenous administration and oral administration:
- dizziness;
- fatigue;
- headache;
- tremor;
- excitation.
The Vidal reference book reports that in isolated cases the following was recorded in patients:
- sweating;
- gait disturbances;
- peripheral sensitivity disorders;
- tides;
- intracranial hypertension;
- depression;
- feeling of fear;
- visual disturbances;
- flatulence;
- stomach ache;
- indigestion;
- nausea, vomiting;
- diarrhea;
- hepatitis;
- hepatocyte necrosis;
- tachycardia;
- arterial hypertension (rare);
- skin itching;
- the appearance of skin rashes.
Extremely rare side effects: bronchospasm , anaphylactic shock , Quincke's edema , arthralgia , Petecia , malignant exudative erythema , vasculitis , leyella syndrome , , eosinophilia, anemia , hemolytic and leukocytosis , Biliriber Biliribor , , Biliribor, Biliribor, Biliribor, Biliribor, Biliriborin. ALP, liver transaminases, creatinine .
Use in ophthalmology is accompanied by:
- often - a feeling of discomfort and/or the presence of a foreign body in the eye, the appearance of a white coating (usually in patients with ulcerative keratitis and with frequent use of drops), the formation of crystals/scales, itching and hyperemia of the conjunctiva, tingling and burning;
- in isolated cases - keratitis / keratopathy , eyelid swelling, corneal staining, hypersensitivity reactions, lacrimation, decreased visual acuity, photophobia, corneal infiltration.
Side effects that are or may be associated with the use of the drug are usually mild, harmless and go away without treatment.
In patients with ulcerative keratitis, the white plaque that appears does not have a negative effect on the treatment of the disease and visual parameters and disappears on its own. As a rule, it appears within 1-7 days after the start of the drug course and disappears immediately or within 13 days after its cessation.
Non-ophthalmological disorders when using drops: the appearance of an unpleasant taste in the mouth, in rare cases - nausea, dermatitis.
When used in otology, the following are possible:
- often - itching in the ear;
- in some cases - ringing in the ears, headache, dermatitis.
Instructions for use of Ciprofloxacin
Ciprofloxacin tablets: instructions for use
The daily dose for an adult varies from 500 mg to 1.5 g/day. It should be divided into 2 doses with an interval of 12 hours.
To prevent crystallization of salts in the urine, the antibiotic should be taken with a large volume of liquid.
A single dose is selected depending on the diagnosis:
- urogenital infections - from 2*250 to 2*500 mg for uncomplicated acute infections, from 2*500 to 2*750 mg for complicated ones;
- cystitis in women before menopause - 500 mg (once);
- respiratory tract infections (depending on the pathogen and severity of the disease) - from 2 * 500 to 2 * 750 mg;
- gonorrhea - 500 mg once for acute uncomplicated and from 2 * 500 to 2 * 750 mg mg if the patient is diagnosed with an extragenital form of the disease, as well as in cases where the disease occurs with complications;
- damage to joints and bones , severe, life-threatening, infections, septicemia, peritonitis (in particular, in the presence of Pseudomonas, Streptococcus or Staphylococcus) - 2 * 750 mg;
- gastrointestinal infections - from 2*250 to 2*500 mg;
- inhalation form of anthrax - 2*500 mg;
- prevention of invasive infections caused by N. meningitidis - 1*500 mg.
Treatment is continued until clinical symptoms are relieved, and for several more days after they disappear and body temperature normalizes. In most cases, the course lasts from 5 to 15 days, in case of damage to joints and bone tissue it is extended to 4-6 weeks, in case of osteomyelitis - up to 2 months.
Patients with renal dysfunction require dose and/or interval adjustment.
Application of ampoules
Ciprofloxacin in ampoules is recommended to be administered intravenously as a drip infusion. The dose for an adult is 200-800 mg/day. The duration of the course is on average from 1 week to 10 days.
For urogenital infections , damage to joints and bones or ENT organs, the patient is administered 200-400 mg twice a day. For respiratory tract infections , intra-abdominal infections , septicemia , lesions of soft tissues and skin, a single dose for the same frequency of use is 400 mg.
For renal dysfunction, the starting dose is 200 mg, which is subsequently adjusted taking into account Clcr.
When using ampoules in a dose of 200 mg, the infusion duration is 30 minutes, when administering the drug in a dose of 400 mg - 1 hour.
Ciprofloxacin injections are not prescribed.
Ear and eye drops Ciprofloxacin: instructions for use
For ulcerative keratitis, treatment is carried out according to the following scheme:
- 1 day - in the first 6 hours, 2 drops of solution are injected into the conjunctival cavity every 15 minutes, then the intervals between instillations are increased to half an hour (the same single dose - 2 drops);
- Day 2 - 2 drops with an interval of 60 minutes between instillations;
- Days 3-14 - 2 drops with an interval of 4 hours between instillations.
Treatment for ulcerative keratitis may last longer than 14 days. The treatment regimen is selected individually by the attending physician.
For superficial bacterial infections of the eye and its appendages, the standard dose is 1-2 drops with a frequency of use of 4 times a day. In especially severe cases, in the first 48 hours the patient is instilled with 1-2 drops every 2 hours.
Treatment lasts from 7 to 14 days.
nasolacrimal occlusion is recommended to reduce systemic absorption of the drug injected into the eye .
In case of concomitant treatment with other ophthalmic drugs for topical use, 15-minute intervals should be maintained between their administration and the administration of Ciprofloxacin.
In otology, the standard dose of the drug is 4 drops into the previously cleaned ear canal of the affected ear, 2 times a day.
For patients using ear tampons, the dose is increased only when using the drug for the first time: children are given 6 drops, adults - 8 drops.
The course should not last more than 10 days. If it is necessary to extend it, the sensitivity of the local flora should be determined.
If other topical agents are used, an interval of 10-15 minutes must be maintained between their administration and the administration of Ciprofloxacin.
Dosage for children over 15 years of age: 3 drops twice a day.
The effect of renal/liver dysfunction on the pharmacokinetic parameters of the drug in the form of ear and eye drops has not been studied.
To avoid vestibular stimulation, the solution is warmed to body temperature before being introduced into the ear canal.
The patient should lie on the side opposite the affected ear. It is recommended that he remain in this position for another 5-10 minutes after instilling the solution.
It is also allowed, after local cleansing, to insert a swab made of absorbent cotton wool or gauze soaked in the solution into the ear canal for 1-2 days. To saturate the drug, it should be moistened twice a day.
To avoid contamination of the tip of the dropper bottle and solution, do not touch the dropper to the eyelids, auricle, external auditory canal, adjacent areas and any other surfaces.
Additionally
There is no fundamental difference in how to take drugs from different manufacturers: the instructions for use of Ciprofloxacin-AKOS are similar to the instructions for Ciprofloxacin-FPO , Ciprofloxacin-Promed , Vero-Ciprofloxacin or Ciprofloxacin-Teva .
For children and adolescents under 18 years of age, it is recommended to prescribe the drug only if the pathogen is resistant to other chemotherapeutic agents.
Overdose
There are no specific symptoms for an overdose of Ciprofloxacin. The patient is advised to lavage the stomach, take emetics, create an acidic urine reaction, and administer a large volume of fluid. All activities should be carried out against the background of maintaining the function of vital systems and organs.
Peritoneal dialysis and hemodialysis help remove 10% of the dose taken.
The drug does not have a specific antidote.
Tsifran
Manufacturer: RANBAXI, India
Release form: tablets
Active ingredient: ciprofloxacin
Zipfran is an analogue of Ciprofloxacin for children, since the drug can be taken from 5 years of age. Refers to broad-spectrum antimicrobial agents.
The analogue is recommended to be taken for the following disorders:
Infectious and inflammatory diseases of the respiratory tract, gastrointestinal tract, genitourinary system, bone system, joints, skin, ENT infections.
- infections due to immunodeficiency;
- prevention and treatment of postoperative infection.
Before starting the course, it is recommended to carefully read the contraindications in order to exclude complications and adverse reactions from the body. The analogue of Zipfran, like Ciprofloxacin, is dispensed from pharmacies only by prescription.
Substitutes for Ciprofloxacin are antibiotics, broad-spectrum antimicrobial agents. Before starting the course, it is imperative to exclude contraindications and take into account drug interactions.
Interaction
Use in combination with Theophylline helps to increase plasma concentration and increase T1/2 of the latter.
Al/Mg containing antacids help slow down the absorption of ciprofloxacin and thereby reduce its concentration in the urine and blood. Between doses of these drugs, intervals of at least 4 hours should be maintained.
Probenecid delays the elimination of the drug.
Ciprofloxacin enhances the effect of coumarin anticoagulants .
The interaction of Ciprofloxacin for use in otology and ophthalmology with other drugs has not been studied.
special instructions
Due to the likelihood of side effects from the central nervous system in patients with a history of its pathology, the drug can be used exclusively for health reasons.
Ciprofloxacin is prescribed with caution when the threshold for convulsive readiness is lowered, epilepsy , brain damage , severe cerebrosclerosis (increases the likelihood of circulatory disorders and stroke ), with serious impairment of liver/kidney function , and in old age.
During the treatment period, it is recommended to avoid UV and solar radiation and increased physical activity, control the acidity of urine and drinking regime.
of crystalluria have been reported in patients with alkaline urine . To avoid its development, it is unacceptable to exceed the therapeutic dose of the drug. In addition, the patient needs to drink plenty of fluids and maintain acidic urine.
Pain in the tendons and the appearance of signs of tenosynovitis are a signal to stop treatment, since the possibility of inflammation/rupture of the tendon cannot be excluded.
Ciprofloxacin may inhibit the speed of psychomotor reactions (especially in the presence of alcohol), which should be kept in mind by patients working with potentially dangerous devices.
If severe diarrhea , pseudomembranous colitis , because this disease is a contraindication to the use of the drug.
If simultaneous intravenous administration of barbiturates is necessary, cardiovascular function should be monitored: in particular, ECG, heart rate, and blood pressure.
The liquid ophthalmic form of the drug is not intended for intraocular injection.
Ciprofloxacin or Ofloxacin – which is better?
Manufacturer: Ozone, Russia
Release form: tablets, solution for infusion
Active ingredient: ofloxacin
Ofloxacin is an analogue of Ciprofloxacin, which is a broad-spectrum antimicrobial agent. Has bactericidal properties. The drug is quickly and completely absorbed from the gastrointestinal tract and is excreted unchanged along with urine.
An analogue is prescribed for infectious diseases of the respiratory tract, skin, genitourinary system, osteoarticular system, abdominal cavity, connective tissue, and ENT organs. Before starting a course of treatment, it is recommended to take into account contraindications, precautions, drug interactions, and possible adverse reactions from the body.
Ciprofloxacin analogs
Level 4 ATC code matches:
Norfloxacin
Synonyms: Ciprofloxacin-Teva , Basijen , Ciprofloxacin-FPO , Ificipro , Ciprofloxacin-Promed , Procipro , Ciprofloxacin-AKOS , Tsiprinol , Ciprodox , Cifran , Ecotsifol , Tseprova .
Analogues of Ciprofloxacin with a similar mechanism of action: Abaktal , Gatispan , Zanotsin , Ivacin , Levotek , Levofloxacin , Moximac , Nolitsin , Ofloxacin , Oflocid , Pefloxacin , Eleflox .
For children
In children, Ciprofloxacin can be used as a 2nd and 3rd line drug for the treatment of complicated UTIs and pyelonephritis caused by E. coli (clinical studies were conducted in children 1-17 years old), to reduce the risk of developing or progressing anthrax in case of aerogenic contact with B. anthracis.
It is also prescribed for the treatment of pulmonary complications caused by P. aeruginosa in children with cystic fibrosis (clinical studies were conducted in a group of patients 5-17 years old).
During the studies, treatment was prescribed only to patients with the above diagnoses. Experience with other indications is limited.
The dosage for children is selected depending on the diagnosis.
Ciprofloxacin during pregnancy
The safety and effectiveness of the drug during pregnancy have not been established.
Animal experiments showed that the drug caused arthropathy . The use of doses exceeding 6 times the average daily dose for humans in pregnant female rats and mice did not provoke any abnormalities in fetal development.
In rabbits receiving 30 and 100 mg/kg Ciprofloxacin orally, gastrointestinal dysfunction was observed and, as a consequence, weight loss and an increase in miscarriage cases. No teratogenic effect was detected.
When the drug was administered into a vein at a dose of 20 mg/kg, there was also no teratogenic effect or toxic effect on the embryo and the mother’s body.
The use of topical Ciprofloxacin during pregnancy is possible if indicated and provided that the benefits to the mother's body outweigh the risks to the fetus.
According to the FDA classification, the drug belongs to category C.
Ciprofloxacin is excreted into milk, so nursing women must decide (taking into account the importance of the drug for the mother) to stop breastfeeding or refuse treatment with Ciprofloxacin.
Local forms are used with caution during lactation, because It is unknown whether the medicine passes into breast milk in this case.
Ciprofloxacin or Ceftriaxone – which is better?
Manufacturer: PHARMSTANDARD+, Russia
Release form: powder for the preparation of solution for injection
Active ingredient: ceftriaxone
Ceftriaxone is a less dangerous analogue of Ciprofloxacin, since the drug can be prescribed during pregnancy (2–3 trimester). The drug belongs to the cephalosporin series of 3rd generation antibiotics with a wide spectrum of action. The product has bactericidal properties. Most of it is excreted from the body unchanged along with urine, and the rest along with feces and bile.
A new generation analogue of Ciprofloxacin is prescribed to patients with infectious diseases of the respiratory tract, skin, genitourinary system, bones, joints, connective tissue, and ENT organs. The product can also be used as a prophylaxis after surgery.
Before starting a course of treatment with an analogue, it is recommended to take into account contraindications, precautions, and drug interactions. Do not exceed the specified dosage in order to exclude an adverse reaction from the body.
Reviews of Ciprofloxacin
Reviews about Ciprofloxacin tablets can be found very different: some consider the drug to be effective, others have the opposite opinion about it. Moreover, almost every review contains references to side effects that occurred during treatment with the drug.
Eye drops are rated by patients as having no disadvantages. They “really heal and heal quickly.”
According to doctors, the advantages of Ciprofloxacin are:
- high bactericidal activity;
- a wide spectrum of antimicrobial action, including Gram (-) and Gram (+) aerobes , mycoplasma , chlamydia , mycobacteria ;
- the ability to penetrate well into the cells and tissues of the macroorganism, creating concentrations there that exceed serum levels or are close to them;
- long T1/2 and the presence of a post-antibiotic effect (thanks to this, it is enough to take the drug only 2 times a day);
- proven effectiveness in the treatment of hospital-acquired and community-acquired infections of any (practically) localization (it is used for sore throat , UTI, infections of bones , skin, etc.);
- Possibility of use for severe infections (in a hospital setting) as
- empirical antibiotic therapy;
- good tolerance.
Ciprofloxacin or Levofloxacin – which is better and more effective?
Manufacturer: Vertex, Russia
Release form: eye drops, tablets, solution for infusion
Active ingredient: levofloxacin
Levofloxacin is an analogue of Ciprofloxacin eye drops. The drug has a large number of contraindications, so before starting the course it is recommended to carefully study the instructions. If the prescribed dosage is not followed, adverse reactions from the body may occur. In this case, you must stop taking the drug and seek qualified help.
A substitute for Ciprofloxacin is prescribed to patients with the following disorders and pathologies:
- Infectious diseases of the upper and lower respiratory tract (pneumonia, chronic bronchitis, sinusitis).
- Infectious lesions of the skin and soft tissues.
- Complicated and uncomplicated infectious diseases of the genitourinary system (with prostatitis).
- Intra-abdominal infection.
Both of these drugs are quite effective and strong for these diseases.
How much does Ciprofloxacin cost?
The average price of Ciprofloxacin in tablets of 500 mg in Ukraine is 22 UAH (package No. 10), the cost of an antibiotic in tablets of 250 mg (package No. 10) is 9-10 UAH. The price of Ciprofloxacin in the form of a solution for infusion therapy is on average 22.5 UAH. The price of an ampoule with eye/ear drops in Kharkov or Kyiv is 17-19 UAH.
In Russian pharmacies the cost of 500 mg tablets is from 33 rubles, 250 mg tablets are from 18 rubles. The solution can be purchased for an average of 35 rubles. The price of Ciprofloxacin eye drops is from 17 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Ciprofloxacin tablets p.p.o.
500 mg 10 pcs. Ozon LLC 39 rub. order - Ciprofloxacin tablets p.p.o. 500 mg 10 pcs. Rapharma JSC
74 RUR order
- Ciprofloxacin solution for inf. 0.2% fl. 100 ml No. 120 (for hospitals) Limited Liability Partnership “Kelun-Kazpharm” (“
RUR 3,521 order
- Ciprofloxacin eye drops 0.3% tube dropper 10 ml RenewalAO Update PFK
41 rub. order
- Ciprofloxacin-AKOS eye drops 0.3% 5ml NOT DEFINED
24 RUR order
Pharmacy Dialogue
- Ciprofloxacin-AKOS (drops 0.3% 5ml) Sintez (Kurgan) OJSC
20 rub. order
- Ciprofloxacin (tab.p.p./vol. 500 mg No. 10) Sintez (Kurgan) OJSC
49 RUR order
- Ciprofloxacin (tab.p.pl/vol. 500 mg No. 10) Ozone LLC
39 RUR order
- Ciprofloxacin bottle 2 mg/ml 100 ml Elfa NPC CJSC/Elfa Laboratories
32 RUR order
- Ciprofloxacin tablets 500 mg No. 10Teva Pharmaceutical
114 RUR order
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Pharmacy24
- Ciprofloxacin 0.2% 100 ml solution
30 UAH. order - Ciprofloxacin 0.25 No. 10 tablets PrAT "Technolog", Uman, Cherkasy region, Ukraine
15 UAH order
- Ciprofloxacin 200 mg 100 ml No. 1 solution
36 UAH order
- Ciprofloxacin 0.2% 100 ml solution
18 UAH order
- Ciprofloxacin 500 mg No. 10 tablets PrAT "Technolog", Uman, Cherkasy region, Ukraine
30 UAH order
PaniPharmacy
- Ciprofloxacin infusion Ciprofloxacin infusion solution 0.2% 100ml Ukraine, Novofarm-Biosintez LLC
18 UAH order
- Ciprofloxacin infusion Ciprofloxacin infusion solution 0.2% 100ml Ukraine, Yuria-Pharm LLC
37 UAH order
- Ciprofloxacin tablets Ciprofloxacin film-coated tablets 0.25g No. 10 Ukraine, OZ GNTsLS LLC
13 UAH order
- Ciprofloxacin tablets Ciprofloxacin film-coated tablets 0.25g No. 10 Ukraine, Tekhnolog ChAO
17 UAH order
- Ciprofloxacin liquid Ciprofloxacin h/o 0.3% 5ml Ukraine, OZ GNTsLS LLC
31 UAH order
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