Sanorin nasal drops with eucalyptus oil emulsion 0.1% fl 10ml

Sanorin nasal drops with eucalyptus oil emulsion 0.1% fl 10ml

Active substance

naphazoline

ATX code

R01AA08 (Naphazoline)

Release form, packaging and composition of the drug

◊ Nasal drops 0.1%

in the form of a white, easily shaken emulsion.

[PRING] ethylenediamine, boric acid, cetyl alcohol, methylparaben, eucalyptus oil, polysorbate 80, cholesterol, liquid paraffin, purified water.

10 ml - dark glass bottles (1) with a SANO dropper and a cap - cardboard packs.

Clinical and pharmacological group

Vasoconstrictor drug for topical use in ENT practice

Pharmacotherapeutic group

Anticongestant - vasoconstrictor (alpha adrenergic agonist)

pharmachologic effect

Data on the pharmacokinetics of the drug Sanorin with eucalyptus oil are not provided.

Indications for use

• acute rhinitis;
• sinusitis;
• eustachitis;
• laryngitis;
• to facilitate rhinoscopy;
• the need to stop nosebleeds.

Dosage

For adults

Prescribe 1-3 drops in each nasal passage 2-3 times a day. Use short-term, no more than 1 week. If nasal breathing becomes easier, then the use of Sanorin with eucalyptus oil can be stopped earlier. Repeated use of the drug is possible after a few days.

The bottle must be shaken before use. An open bottle of the drug can be used for 4 weeks.

Contraindications

• chronic rhinitis;
• arterial hypertension;
• severe atherosclerosis;
• tachycardia;
• thyrotoxicosis;
• diabetes;
• simultaneous use of MAO inhibitors and a period of up to 14 days after the end of their use;
• children under 15 years of age;
• hypersensitivity to the components of the drug.

Overdose

Symptoms:

Long-term or frequent administration of the drug Sanorin with eucalyptus oil into the nasal cavity can cause swelling of the nasal mucosa and a feeling of congestion. The danger of overdose (especially if swallowed) of the drug Sanorin with eucalyptus oil occurs in young children and can cause depression of the central nervous system, the manifestations of which are drowsiness, decreased body temperature, increased sweating, slowed heart rate, increased blood pressure or its subsequent decrease, and extremely rarely - coma .

Treatment:

carrying out symptomatic therapy.

Side effects

From the digestive system:

nausea.

From the cardiovascular system:

tachycardia, increased blood pressure.

From the side of the central nervous system:

headache, irritability.

Allergic reactions:

rash.

Local reactions:

reactive hyperemia, swelling of the nasal mucosa; when used for more than 1 week - irritation, in some cases - swelling of the nasal mucosa.

Overdose

Concomitant use with MAO inhibitors and for a period of up to 14 days after the end of their use increases the risk of developing severe arterial hypertension (release of deposited catecholamines under the influence of naphazoline).

Slows down the absorption of local anesthetics.

Storage conditions

The drug should be stored out of the reach of children, protected from light at a temperature of 10° to 25°C. Shelf life – 4 years.

Conditions for dispensing from pharmacies

The drug is approved for use as a means of OTC.

Special Instructions

With long-term use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended that after 5-7 days of use in adults, take a break for several days.

The drug may have a resorptive effect.

The need to use the drug Sanorin with eucalyptus oil with other medications is determined by the doctor individually.

Sanorin (drops 0.1% 10ml with eucalyptus oil)

A country

Czech Republic
Country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.

Active substance

Naphazoline

Compound

Bottle 10 ml
Naphazoline nitrate 10 mg. Excipients: ethylenediamine, boric acid, cetyl alcohol, methylparaben, eucalyptus oil, polysorbate 80, cholesterol, liquid paraffin, purified water. Nasal drops 0.1% in the form of a white, easily shaken emulsion.

pharmachologic effect

Alpha2-adrenergic agonist. When applied topically, it has a rapid, pronounced and long-lasting vasoconstrictor effect on the vessels of the mucous membrane (reduces swelling, hyperemia, exudation). Facilitates nasal breathing during rhinitis. After 5-7 days of use, tolerance occurs.

Indications for use

- acute rhinitis; - sinusitis; - eustachitis; - laryngitis; — to facilitate rhinoscopy; - the need to stop nosebleeds.

Side effects

From the digestive system: nausea. From the cardiovascular system: tachycardia, increased blood pressure. From the central nervous system: headache, irritability. Allergic reactions: rash. Local reactions: - reactive hyperemia, swelling of the mucous membrane of the nasal cavity; - when used for more than 1 week - irritation, in some cases - swelling of the nasal mucosa.

Contraindications

- chronic rhinitis;
- arterial hypertension; - severe atherosclerosis; - tachycardia; - thyrotoxicosis; - diabetes; - simultaneous use of MAO inhibitors and a period of up to 14 days after the end of their use; - children under 15 years of age; - hypersensitivity to the components of the drug. Use during pregnancy and breastfeeding Data on the safety of the drug during pregnancy and lactation (breastfeeding) are not provided.

Use in children Contraindication: children under 15 years of age.

Mode of application

Adults are prescribed 1-3 drops in each nasal passage 2-3 times a day. Use short-term, no more than 1 week. If nasal breathing becomes easier, then the use of Sanorin with eucalyptus oil can be stopped earlier. Repeated use of the drug is possible after a few days. The bottle must be shaken before use. An open bottle of the drug can be used for 4 weeks.

special instructions

With long-term use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended that after 5-7 days of use in adults, take a break for several days. The drug may have a resorptive effect. The need to use the drug Sanorin with eucalyptus oil with other medications is determined by the doctor individually.

Overdose

Symptoms: prolonged or frequent administration of the drug Sanorin with eucalyptus oil into the nasal cavity can cause swelling of the nasal mucosa and a feeling of congestion. The danger of overdose (especially if swallowed) of the drug Sanorin with eucalyptus oil occurs in young children and can cause depression of the central nervous system, the manifestations of which are drowsiness, decreased body temperature, increased sweating, slowed heart rate, increased blood pressure or its subsequent decrease, and extremely rarely - coma . Treatment: symptomatic therapy.

Interaction with other drugs

Concomitant use with MAO inhibitors and for a period of up to 14 days after the end of their use increases the risk of developing severe arterial hypertension (release of deposited catecholamines under the influence of naphazoline). Slows down the absorption of local anesthetics.

Sanorin 0.1% 10ml nasal spray [with menthol and eucalyptus]

pharmachologic effect

Anticongestant - alpha-adrenergic agonist.

Composition and release form Sanorin 0.1% 10ml nasal spray [with menthol and eucalyptus]

Spray - 1 ml.:

• Active ingredients: naphazoline nitrate - 1 mg;
• Excipients: boric acid - 16 mg, liquid sorbitol (non-crystallizing) - 14 mg, macrogol glyceryl hydroxystearate - 2.5 mg, levomenthol - 0.3 mg, cineole (eucalyptol) - 0.2 mg, water for injection - up to 1 ml.

10 ml - bottles (1) complete with a spray device - cardboard packs.

Description of the dosage form

Nasal spray [with menthol and eucalyptus] in the form of a clear, colorless or slightly colored liquid with a characteristic odor.

Directions for use and doses

Used intranasally and locally in ophthalmology. The dosage regimen is individual, depending on the indications and the dosage form used.

Pharmacodynamics

Alpha adrenergic agonist. When applied to the mucous membranes, it has a rapid, pronounced and long-lasting vasoconstrictor effect.

Pharmacokinetics

When applied topically, systemic absorption is low.

Indications for use Sanorin 0.1% 10ml nasal spray [with menthol and eucalyptus]

For intranasal use: acute rhinitis, allergic rhinitis, sinusitis, eustachitis, laryngitis, laryngeal edema of allergic origin, laryngeal edema due to irradiation, hyperemia of the mucous membrane after operations on the upper respiratory tract, to facilitate rhinoscopy, to stop nosebleeds, to prolong the effect local anesthetics used for superficial anesthesia.

For use in ophthalmology: symptomatic temporary relief of secondary ocular hyperemia due to mild irritants and allergic conjunctivitis.

Contraindications

Hypersensitivity to naphazoline, arterial hypertension, severe atherosclerosis, thyrotoxicosis, chronic rhinitis, atrophic rhinitis, severe eye diseases, angle-closure glaucoma, diabetes mellitus, tachycardia, concomitant use of MAO inhibitors and a period of up to 14 days after the end of their use; children's age - depending on the dosage form.

With caution: coronary artery disease, prostatic hyperplasia; pheochromocytoma; pregnancy, breastfeeding period; hyperthyroidism, diabetes mellitus, porphyria, dry rhinitis, keratoconjunctivitis sicca, glaucoma; use of other drugs that increase blood pressure.

Use of Sanorin 0.1% 10ml nasal spray [with menthol and eucalyptus] during pregnancy and breastfeeding

The use of naphazoline during pregnancy and lactation (breastfeeding) is possible only according to strict indications in cases where the expected therapeutic effect for the mother exceeds the potential risk of side effects in the fetus or child.

special instructions

Naphazoline may have a resorptive effect.

With prolonged intranasal use, the severity of the vasoconstrictor effect of naphazoline gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended to take a break for several days after 5-7 days of use. Long-term use of the product should be avoided.

If, when using eye drops, there is no improvement within 72 hours, or if irritation or redness increases, or eye pain or visual disturbances occur, you should stop using the product and consult a doctor. Direct contact of the product with contact lenses should be avoided. It is recommended to remove contact lenses before using eye drops.

Overdose

Symptoms: hypothermia, bradycardia, hyperhidrosis, drowsiness, coma.

Treatment: symptomatic.

Side effects of Sanorin 0.1% 10ml nasal spray [with menthol and eucalyptus]

Local reactions: when used in ophthalmology - burning, itching, pain in the eye area; reactive hyperemia of the conjunctiva, visual disturbances, dry nasal mucosa, mydriasis, increased intraocular pressure; with intranasal use - reactive hyperemia, swelling of the nasal mucosa, irritation of the nasal mucosa; when used for more than 1 week - swelling of the nasal mucosa, atrophic rhinitis.

Systemic reactions: possible, mainly in children and elderly patients - pallor of the skin, tachycardia, pain in the heart, increased blood pressure, increased sweating, trembling, headache, agitation, nausea, drowsiness, dizziness.

Drug interactions

Should not be used simultaneously with MAO inhibitors or within 14 days after stopping their use.

Naphazoline slows down the absorption of local anesthetics (prolongs their effect during superficial anesthesia).