Composition and release form
The medicine is produced in several forms:
- syrup;
- drops;
- tablets (capsules).
All forms are intended for oral use and are convenient to use.
Active ingredients: castor oil, fir oil, oregano extract, peppermint oil. All components are of plant origin. It also contains Trilon-B, which is responsible for cleansing the body of heavy metal salts.
Additional ingredients in the capsule: magnesium carbonate, lactose, monohydrate, potato starch.
The auxiliary elements in the syrup are: sugar syrup, citric acid.
The tablets consist of the main active substances and Trilon-B.
Pharmacological properties of the drug Urolesan
Urolesan belongs to a group of drugs that promote the removal of urinary and gallstones. The components of essential oils included in Urolesan reduce inflammatory processes, promote increased blood supply to the kidneys and liver, have a diuretic, choleretic and bactericidal effect, form a protective colloid in the urine, and also normalize the tone (reduce spasm) of the smooth muscles of the upper urinary tract and gall bladder . Due to their high solubility and capillary activity, essential oils are easily absorbed into the blood. By stimulating renal and hepatic circulation, they cause an increase in urinary and bile excretion. Urolesan has a pronounced anti-inflammatory effect, promotes the outflow of bile, the removal of small stones from the kidneys, urinary and gall bladders. The drug also exhibits mild sedative properties, which are very important during the passage of stones. The drug is well absorbed, its effect begins 20–30 minutes after administration and lasts 4–5 hours. The maximum effect develops after 1–2 hours. It is excreted in feces and urine.
Pharmacology
Urolesan is a combined agent that has an antiseptic, bile- and diuretic, antispasmodic effect. Also has good antimicrobial activity.
In what cases is the drug prescribed?
The drug is actively taken for pathologies of the urinary system. Medicine in any form is prescribed for the following diseases:
- urolithiasis disease;
- cholelithiasis;
- unspecified kidney problems;
- gallbladder dyskinesia.
Since the composition contains only herbal components, the product is often prescribed for prevention purposes.
Stone upon stone, or a few words about urolithiasis.
Stone upon stone, or a few words about urolithiasis.
In Russia, more than 1 million people are currently registered as suffering from urolithiasis. In total, there are about 3% of patients in the world. The Nizhny Novgorod region is one of the disadvantaged regions for this disease, so the problem is urgent for us. What to do to prevent a “diamond mine” from forming in the kidneys, and what should those who do have the misfortune of “acquainting themselves” with renal colic do? Vera Alekseevna Ladygina, a urologist at the Clinical Diagnostic Center, will talk about this.
Hello, Vera Alekseevna, why do stones form in the kidneys?
There is still no consensus in the medical community on what exactly causes urolithiasis. After all, both kidneys secrete urine. But why then do stones form in one kidney and not in the other? And the composition of the urine passing through both kidneys is the same. Therefore, doctors say that urolithiasis is a disease that is manifested by increased excretion of mineral salts in the urine and the formation of stones in the urinary tract. But how this happens - there are many opinions about this, but there is still no complete and unambiguous answer to this question.
Who is more susceptible to this disease? Who is at risk?
Naturally, these are people with kidney diseases - acquired or hereditary, for example, kidney anomalies, horseshoe kidney, etc. In healthy kidneys, stones never form. Urinary tract infections and urinary tract abnormalities contribute to increased crystallization of salts in the urine. After all, urine is a saline solution, but the salts are dissolved in it, and through healthy kidneys these salts come out along with the urine, and when there are some diseases, the crystals precipitate and grow into stones. It is still not clear why these crystals linger in the kidneys, because nothing prevents them from leaving while they are still small. There may be a small stone in one kidney and a large one in the other. So the process of stone formation itself has not yet been sufficiently studied.
Does a person’s age affect the formation of stones?
Stones can form even in newborns. Moreover, they are large, and they have to be crushed immediately. This indicates that the child has a congenital disease of the genitourinary organs.
Who suffers more often from stones? Men or women?
Men. This is due to the fact that women have the hormone estrogen, which prevents crystals from sticking together into stones. I repeat, if the kidneys are healthy, stones will never form.
How does urolithiasis manifest itself?
Pain in the abdomen and lower back is an essential component of urolithiasis. There are people who are patient and do not pay attention to pain for a long time. As a result, doctors discover large stones. People don’t go to the doctor for a long time because a large stone behaves more or less calmly, sometimes giving a dull, aching pain. A small stone gives severe sharp pain in the form of renal colic. Well, the second main sign is blood in the urine. As a rule, there can be a lot of it, and the patient sees it “by eye,” which indicates that the stone is moving. The disease is diagnosed by ultrasound and based on the results of urine tests, the composition of the salts in the urine can already be used to predict the composition of the stone.
What kind of stones do Nizhny Novgorod residents have?
In our region, as in general and throughout the country, oxalates predominate (up to 75%). In second place are phosphate stones (up to 15%), then urate stones (2-7%) and cystine stones - up to 3%. They differ in composition.
How can you alleviate your condition during renal colic?
There is a good and safe medicine - Urolesan, consisting only of herbs. For patients with urolithiasis, it is always at hand. Taking this medicine will relieve the pain of renal colic, if the attack that happened is just that. This is the only thing the patient can do before the doctor arrives. The main thing is to consult a doctor immediately; prolonged presence of a kidney stone is fraught with purulent inflammation and loss of the organ.
That is, advice from the Internet - lie in a hot bath and take No-shpu - is this bad advice?
Undoubtedly. No hot bath or painkillers, because you yourself will not be able to determine the cause of the pain. What if you don’t have renal colic, but an attack of acute appendicitis? What if a woman has an ectopic pregnancy? In medical terminology, there is the concept of “acute abdomen” - this is a condition in acute appendicitis, acute cholecystitis, intestinal colic, ectopic pregnancy... In this condition, the clock counts for making a diagnosis before surgery. Pain in renal colic and in these dangerous conditions can easily be confused, so you should never engage in self-diagnosis or self-medication. Urolesan didn’t help, which means you don’t have renal colic. Let the doctor figure it out; renal colic, unlike the other above-mentioned conditions, can be observed for three days to make a diagnosis and make further decisions on treatment or surgery.
By the way, about operations. People who have not encountered the problem say that the stones are somehow “crushed.” Others say they are being operated on. Tell us what treatment methods are currently used.
Nowadays, abdominal operations are performed only when absolutely necessary. Surgical treatment has become more comfortable. Basically, minimally invasive endoscopic operations are used, when a stone is removed through a puncture in the lumbar region, or crushed by applying electrodes to it, again, through a puncture, or through the urinary tract. There is also a non-surgical method of crushing stones - lithotripsy, when a special device is aimed at the kidney area at the stone and, with the help of short pulses of energy, destroys it step by step until small particles remain from the stone, which themselves are excreted in the urine. The doctor chooses the methods himself. It happens that drug treatment is enough. And so, they split it up, observed it for two or three days, and went home. There are practically no complications when crushing stones.
If the stone is removed, can you continue to live in peace?
Unfortunately, no, with urolithiasis the likelihood of relapse is extremely high. No matter how effectively the operation is performed, it will not be possible to do without complex and individually selected drug therapy. Patients should be observed after surgery by a urologist for several years.
What should you drink and eat to avoid any stones?
A healthy person needs to drink 2-2.5 liters of fluid per day, preferably plain water. I'll explain why. Plain water does not cause digestion in the stomach. Like a shower, it passes through the entire body, internal organs, including the kidneys, washes them and leaves. If we drink other liquids - juice, compote, tea, coffee - the stomach begins to work, gastric juice, hydrochloric acid, enzymes, etc. are released. If you have been diagnosed with urolithiasis, drink 3-3.5 liters of water per day. As for taking vitamins, for example, calcium, everything should be in moderation. The diet should be rich in fiber. It is advisable to consume a lot of plant foods. Fiber, or dietary fiber, is useful in that it absorbs a lot of water and swells, stretching the stomach and preventing overeating, because. the stomach considers itself more “full”, this is a plus. The second advantage is that then this swollen lump of food, rich in fiber, cleanses the digestive tract without leaving solid mineral substances on the walls - the same ones that, being absorbed into the blood, then enter the kidneys and form crystals. Meat and fish should only be limited if you have uric acid stones. For other types of stones, these foods can be eaten.
Returning to the issue of water. Our region has very hard water. Does this affect the health of Nizhny Novgorod residents?
The Volga region is indeed an unfavorable region for urolithiasis due to increased water hardness. Water must be boiled before use. But, most importantly, take care of your own health. I repeat, if your kidneys are healthy, there is nothing to be afraid of.
In addition to drinking the right amount of water and proper nutrition, it is important to avoid prolonged stressful situations, stress provokes the formation of stones. Need more rest. Physical activity is important. And then you will not face urolithiasis.
Interviewed by Danila Rezak.
What foods to look for fiber in?
These are wheat bran, bread (rye flour, Borodino, whole grain flour), porridge (buckwheat, pearl barley, oatmeal, wheat), nuts (almonds, pistachios, hazelnuts and walnuts), mushrooms, legumes (green beans, peas, lentils ). Vegetables: cabbage (Brussels sprouts, cabbage), carrots, beets, zucchini, pumpkin, tomatoes. There is also a lot of fiber in greens - parsley, dill, lettuce, green onions. And also in fruits, dried fruits and berries - such as black currants, dried apricots, dried apples, raisins, prunes, pears, oranges, bananas, apricots, raspberries, strawberries and others.
The champions in fiber content are: wheat bran, dried apricots, black currants, dried apples and raisins.
Important: The operation for remote crushing of stones (extracorporeal lithotripsy) is carried out free of charge within the framework of the “Program of state guarantees of free provision of medical care to the population of the Nizhny Novgorod region for 2021”. In particular, remote lithotripsy according to compulsory medical insurance is performed at the State Budgetary Healthcare Institution "City Clinical Hospital 13 of Nizhny Novgorod". You can find out where else such operations are carried out under compulsory medical insurance by contacting the Territorial Health Insurance Fund of the Nizhny Novgorod Region.
Article provided by the advertising and information weekly 'Arena'.
Can it be given to children?
Urolesan in the form of syrup can be given to children from the first days of life. Used to treat diseases of the urinary system. The treatment regimen is as follows: children under 2 years old can be given 3-6 ml per day, children aged 2-7 years can be prescribed up to 12 ml per day, children aged 7 to 14 years can take up to 15 ml per day.
Regardless of age, the prescribed daily dose should be divided into 3 doses. It is strictly not recommended to exceed this value. Only an experienced doctor can increase the dose if there are appropriate indications.
UROLESAN. INSTRUCTIONS FOR USE. syrup
INSTRUCTIONS FOR USE
UROLESAN
UROLESAN
Trade name of the drug: Urolesan
Release form: Syrup. 90 ml in jars or bottles; 180 ml in bottles, included in a pack along with a dosing syringe.
Compound:
100 ml of syrup contains:
Active ingredients: fir oil – 0.419 g, peppermint oil – 0.105 g, wild carrot fruit extract liquid (1:1) – 1.204 g, hop cones extract liquid (1:1) – 1.726 g, oregano herb extract liquid (1: 1) – 1.195 g;
Excipients: polysorbate-80; citric acid, monohydrate; sorbic acid; sugar syrup; disodium edetate; purified water.
Description: The liquid is light yellow in color with a greenish tint, with a specific odor. Opalescence is allowed.
Pharmacotherapeutic group: drugs used in urology.
ATX code: G04B X.
Pharmacological properties
Combined preparation of plant origin. The components of the drug Urolesan reduce inflammation in the urinary tract and kidneys, promote increased blood supply to the kidneys and liver, have a diuretic, antibacterial, choleretic effect, form a protective colloid in the urine and normalize the tone of the smooth muscles of the upper urinary tract and gall bladder.
Urolesan increases the release of urea and chlorides, promotes the removal of small stones and sand from the bladder and kidneys.
Pharmacokinetics
The drug is well absorbed, its effect begins after 20-30 minutes and lasts 4-5 hours. The maximum effect occurs after 1-2 hours. It is excreted through the digestive tract and by the kidneys.
Indications for use
Acute and chronic infections of the urinary tract and kidneys (cystitis and pyelonephritis); urolithiasis and uric acid diathesis (prevention of the formation of stones after their removal); chronic cholecystitis (including calculous), biliary dyskinesia, cholelithiasis.
Directions for use and doses
The drug is taken orally before meals.
Recommended doses for adults: 1 teaspoon (5 ml) of syrup 3 times a day. For acute conditions (including renal and hepatic colic), the duration of the course of therapy is from 5 to 7 days, for chronic conditions - from 7 days to 1 month. If renal and hepatic colic occur, the single dose can be increased once to 2 teaspoons (10 ml), then at the next dose return to the usual single dose (5 ml).
Recommended doses for children: 1-2 years – 1-2 ml 3 times a day; 2-7 years – 2-4 ml 3 times a day; 7-14 years – 4-5 ml 3 times a day. Dosage is carried out using a dosing syringe.
Side effects
Urolesan is usually well tolerated. When using the drug the following are possible:
– from the digestive tract: dyspeptic symptoms (nausea, vomiting);
– allergic reactions: itching, facial redness, skin rash, angioedema (sore throat, difficulty breathing, swelling of the face, tongue);
– from the central and peripheral nervous system: dizziness, general weakness;
– from the cardiovascular system: arterial hypertension, hypotension.
Contraindications.
– Hypersensitivity to the components of the drug;
– gastritis, peptic ulcer of the stomach and duodenum.
Drug interactions
Not studied.
special instructions
Do not use the drug if the diameter of the stones exceeds 3 mm.
Patients with diabetes mellitus, as well as patients with high blood glucose levels, need to be careful when using Urolesan (the drug contains sugar syrup).
Use during pregnancy or breastfeeding. The use of the drug during pregnancy or lactation has not been studied.
The ability to influence the reaction rate when driving a vehicle or working with other mechanisms. No messages.
Children. The drug is not used in children under 1 year of age.
The drug should not be used after the expiration date and should be stored out of the reach of children.
Overdose
In case of overdose, possible: nausea, dizziness.
Treatment: plenty of warm drinks, rest, activated carbon, atropine sulfate (0.0005-0.001 g).
Storage conditions
In original packaging at temperatures from 8°C to 15°C. After opening, store for no more than 28 days at a temperature of 8°C to 15°C.
Best before date
2 years
Conditions for dispensing from pharmacies
Over the counter.
Manufacturer's name and address.
JSC "Galichfarm", Ukraine, 79024, Lvov, st. Opryshkovskaya, 6/8.
special instructions
Interaction with other drugs has not been established.
The drops contain more than 50% ethyl alcohol, and, therefore, they cannot be prescribed for alcoholism, and it is also worth avoiding parallel use with alcoholic beverages.
Drops and syrup are stored for 24 months, capsules - 36 months.
The syrup should be stored in a dark place at a temperature of 10-15 degrees. From the moment of opening it can be stored for no more than a month.
Drops and capsules are stored at a temperature of no more than 25 degrees in a place out of direct sunlight and out of reach of children.
Urolesan 25ml drops for oral administration
pharmachologic effect
Antiseptic, metabolic. Antispasmodic agent of plant origin.
Composition and release form Urolesan 25ml drops for oral administration
Drops for oral administration - 100 g:
- fir oil - 8 g; peppermint oil - 2 g; castor oil - 11 g; alcoholic extract of wild carrot seeds - 23 g; alcoholic extract of hop cones - 32.995 g; alcoholic extract of oregano herb - 23 g; Trilon B - 0.005 g.
In dark glass bottles of 15 ml, complete with a dropper stopper; 1 set in a cardboard pack or in dark glass dropper bottles of 15 or 25 ml; 1 bottle in a cardboard pack.
Description of the dosage form
The liquid is greenish-brown to brown in color, with a characteristic mint odor.
Characteristic
Antispasmodic agent of plant origin.
Directions for use and doses
Take 8-10 drops orally on a piece of sugar 3 times a day before meals.
The duration of treatment depends on the severity of the disease and ranges from 5 to 30 days. For renal and hepatic colic, the single dose can be increased to 15-20 drops. Increasing the single dose, duration and repeating the course of treatment is possible only on the recommendation of a doctor.
Pharmacodynamics
It has antiseptic (disinfecting) properties, increases diuresis (urination), acidifies urine, increases the secretion of urea and chlorides, enhances bile formation and bile secretion, improves hepatic blood flow.
The drug has antispasmodic, anti-inflammatory, antiseptic effects, enhances bile formation and excretion, increases diuresis, acidifies urine, increases the excretion of urea and chlorides.
Pharmacokinetics
Urolesan® is a complex of biologically active components; therefore, its pharmacokinetic studies are not possible.
Indications for use Urolesan 25ml drops for oral administration
- various forms of urolithiasis and cholelithiasis;
- acute and chronic pyelonephritis (kidney disease);
- cholecystitis (inflammation of the gallbladder);
- cholangiohepatitis (combined inflammation of the liver and bile ducts) and dyskinesia (impaired mobility) of the bile ducts.
In the complex therapy of acute and chronic urinary tract and kidney infections (cystitis, pyelonephritis); urolithiasis, cholelithiasis, chronic cholecystitis, biliary dyskinesia of the hyperkinetic type.
Contraindications
- Hypersensitivity to the components of the drug;
- Lactose intolerance, lactase deficiency or glucose-galactase malabsorption;
- Hyperacid gastritis, peptic ulcer of the stomach and duodenum;
- The diameter of kidney stones exceeds 3 mm;
- Age up to 18 years.
Use of Urolesan 25ml drops for oral administration during pregnancy and breastfeeding
The use of the drug during pregnancy and breastfeeding is contraindicated (efficacy and safety have not been studied).
special instructions
Do not use the drug if the diameter of kidney stones exceeds 3 mm.
The drug contains 60% ethyl alcohol. In the maximum single dose of the drug, the content of absolute ethyl alcohol is 0.47 g, in the maximum daily dose of the drug - 1.42 g.
Impact on the ability to drive vehicles and operate machinery
In recommended doses, the drug does not affect the ability to perform potentially hazardous activities that require special attention and quick reactions.
Overdose
There may be an increase in dose-dependent side effects (including nausea, vomiting, dizziness). Treatment is symptomatic: plenty of warm drinks, rest, activated carbon, atropine sulfate (0.0005-0.001 g)
Side effects Urolesan 25ml drops for oral administration
Slight dizziness and nausea are possible. In this case, plenty of hot drinks and rest are prescribed.
- From the digestive system: dyspeptic symptoms (heartburn, nausea, vomiting, diarrhea);
- Allergic reactions: itching, redness of the face, skin rash, angioedema (sore throat, difficulty breathing, swelling of the face, tongue);
- From the central and peripheral nervous system: dizziness, general weakness;
- From the cardiovascular system: increase/decrease in blood pressure.
Drug interactions
Interaction with other drugs has not been described.
Indications for use of the drug Urolesan
Urolesan liquid : prescribed to adults and children over 7 years of age for the treatment of urinary and cholelithiasis, urinary diathesis, acute and subacute calculous pyelonephritis and chronic cholecyst, biliary dyskinesia. Urolesan syrup: acute and chronic urinary tract infections (cystitis and pyelonephritis); urolithiasis and uric acid diathesis (prevention of the formation of stones after their removal); chronic cholecystitis (including calculous), biliary dyskinesia, cholelithiasis.
Use of the drug Urolesan
Take orally before meals. Urolesan liquid , 8-10 drops on a piece of sugar under the tongue 3 times a day. Duration of treatment is 5–30 days. Repeated courses are possible if necessary. For renal and hepatic colic, the single dose can be increased to 15–20 drops. Doses for children aged 7-14 years – 5-6 drops (for sugar) 3 times a day. Urolesan syrup Doses for adults: 1 teaspoon (5 ml) of syrup 3 times a day before meals. The duration of the course of therapy is determined individually, depending on the effectiveness of treatment and, as a rule, ranges from 5 to 7 days for acute conditions and from 7 days to 1 month for chronic conditions. For renal and hepatic colic, the single dose can be increased to two teaspoons (10 ml once), and then return to the usual dose (5 ml). Doses for children: 1 - 2 years - 1 - 2 ml 3 times a day; 2-7 years - 2 - 4 ml 3 times a day; 7 - 14 years - 4 - 5 ml 3 times a day (using a dosing syringe).
